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Researcher

Dr Rebecca Lehmann

Biography

Dr. Rebecca Lehmann is currently a postdoctoral researcher in the Brain Tumour group at the Children's Cancer Institute, under the supervision of Dr. Ben Rayner and Prof. David Ziegler. Rebecca graduated from a Bachelor of Biomedical Science in 2013 from the University of Adelaide with First Class Honours, and received her PhD from the University of Adelaide in 2019. During her PhD candidature, Rebecca investigated the mechanisms underlying...view more

Dr. Rebecca Lehmann is currently a postdoctoral researcher in the Brain Tumour group at the Children's Cancer Institute, under the supervision of Dr. Ben Rayner and Prof. David Ziegler. Rebecca graduated from a Bachelor of Biomedical Science in 2013 from the University of Adelaide with First Class Honours, and received her PhD from the University of Adelaide in 2019. During her PhD candidature, Rebecca investigated the mechanisms underlying the severe neurological pathology of the paediatric neurodegenerative disease, Mucopolysaccharidosis, examining the effects of increased heparan sulphate content and aberrant sulphation patterning on stem cell differentiation. In 2019, following completion of her PhD, Rebecca started as a postdoctoral researcher in the Brain Tumour Group at the Children's Cancer Institute. Her work focuses on identifying new treatments for children with the universally lethal brain tumour, Diffuse Midline Glioma, and other hard to treat childhood brain tumours. 


My Grants

Perpetual IMPACT Philanthropy Grant (2023 - 2024): A better treatment for drug-resistant childhood brain cancer


My Qualifications

Bachelor of Science (BiomedSc), University of Adelaide, 2010-2012

Bachelor of Science (Hons), University of Adelaide, 2013

PhD, University of Adelaide, 2015-2019

 

 


My Awards

2023    Cancer Institute NSW Travel Grant

2023    Kids Cancer Alliance (KCA) Childhood Cancer Symposium ECR Oral Presentation First Prize

2023    Australian Society for Medical Research (ASMR) National Conference EMCR Poster Award

2022    Children's Cancer Institute Research Symposium Outstanding ECR Poster Presentation Award

2021    University of Adelaide AMS/Biomedicine Publication Award

2018    Fresh Science Competition South Australian Finalist

2018    Hospital Research Foundation BioMed City Travel Award 

2018    National Stem Cell Foundation of Australia Travel Award

2018    Walter and Dorothy Duncan Trust Travel Grant 

2017    Australian and New Zealand Society for Cell and Developmental Biology (ANZSCDB) Outstanding Student Oral Presentation Prize

2017    Australasian Society of Stem Cell Research (ASSCR) Travel Award

2015    Matrix Biology Society of Australia and New Zealand (MBSANZ) Travel Award

2015    Australian Postgraduate Award (PhD Scholarship)

2013    University of Adelaide Molecular and Biomedical Science Honours Scholarship


My Research Activities

1. Determining the efficacy of CDK4/6 inhibitor combination treatments for Diffuse Midline Glioma

2. Identifying new treatments for BRAF/MEK inhibitor resistant paediatric brain tumours

 


My Research Supervision


Areas of supervision

Honours and PhD Projects currently available:

- Drug resistance in paediatric high-grade glioma

Drug resistance is a constant obstacle to developing effective treatments in paediatric high-grade glioma. This project will focus on developing novel treatments against BRAF-inhibitor resistant paediatric high-grade glioma and determining their efficacy in vitro and in vivo

- Cell cycle inhibitors in diffuse midline glioma

The cell cycle is frequently dysregulated in diffuse midline glioma, the most lethal paediatric brain tumour. This project focuses on identifying new therapies which target cell cycle dysregulation, both in vitro and in vivo

 


Currently supervising

Honours Students:

2022

Joshua Zhu

Project: Overcoming drug resistance in BRAFV600E mutant paediatric high-grade gliomas

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Location

Children's Cancer Institute