Researcher

Dr Selene Fernandez Valverde

Keywords

Fields of Research (FoR)

Bioinformatics and computational biology, Genomics and transcriptomics, Evolutionary biology, Plant biology

Biography

Selene is a genomic scientist & bioinformatician interested in understanding the role non-coding RNAs play in the evolution of gene regulatory landscapes within and across eukaryotes.

She is a Senior Lecturer RNA New Research Talent Program (Level C) funded by the UNSW RNA Institute. Her laboratory focuses on studying the evolution of long non-coding RNAs in various plants and animals to predict their functions better using bioinformatic tools...view more

Selene is a genomic scientist & bioinformatician interested in understanding the role non-coding RNAs play in the evolution of gene regulatory landscapes within and across eukaryotes.

She is a Senior Lecturer RNA New Research Talent Program (Level C) funded by the UNSW RNA Institute. Her laboratory focuses on studying the evolution of long non-coding RNAs in various plants and animals to predict their functions better using bioinformatic tools and genomic approaches. She is particularly interested in how these could be leveraged to impact food production and disease in crops and humans. 

Dr. Fernandez holds a BSc in Genomic Sciences from the National Autonomous University of Mexico (2007). She completed her doctorate at the University of Queensland (UQ), studying new classes of small RNAs with Prof. John Mattick in 2013. As a postdoc, she used comparative genomics to identify regulatory changes that facilitated the evolution of multicellular organisms and morphological diversity in the animal kingdom in the laboratory of Prof. Bernie Degnan, UQ (2012-2015). She then returned to her native Mexico as a Principal Investigator at the Advanced Genomics Unit of Cinvestav (2016-2023) before joining UNSW as a Senior Lecturer in mid-2023.  

Dr. Fernandez was awarded the Mexico national scholarship L’Oreal-UNESCO-AMC-CONACYT for Women in Science in 2016, the International Rising Talents Fellowship of L’Oreal-UNESCO in 2018 and the Gender Equality Award by the International Union of Immunological Societies in 2019. She is a founding member of Mas Ciencia por Mexico (More Science for Mexico), the Mexican Network of Bioinformatics (Red Mexicana de Bioinformática), and a volunteer instructor of Software Carpentry and previously Clubes de Ciencia Mexico.

She has served as a volunteer mentor at foundations such as Ekpapalek and the “Mujeres en STEM: Futuras Líderes” program of the US-Mexico Foundation. Forbes Mexico magazine selected her as one of the 100 most powerful women in Mexico in 2018. She was recently elected in the competitive female climate leadership program 'Homeward Bound' and is part of #TeamHB8. 


My Grants

  • 2021: Bioinformatics training room infrastructure upgrade: increasing bioinformatics training accessibility in Mexico CABANA Training Infrastructure Award, CABANA Innovation Fund, EMBL-EBI, UK (7,925.38 GBP)
  • 2020: Patrones de expresión alelo específicos en lupus eritematoso sistémico durante la inducción de tolerancia (Allele-specific expression patterns in systemic lupus erythematosus during tolerance induction) Convocatoria 2019 de Proyectos de Ciencia de Frontera, Modalidad de Grupo, CONACYT, Mexico ($3,149,880.30 MXN ~285,750 AUD)
  • 2018: Co-expresión tejido específica de dominios estructurales conservados en ARNs largos no codificantes (Tissue-specific co-expression of conserved structural domains in long non-coding RNAs) Convocatoria 2017-2018 de Proyectos de Investigación Científica Básica, Investigador Joven, CONACYT, Mexico ($1,418,200.00 MXN ~128,656 AUD)
  • 2018: The evolutionary dynamics of long non-coding RNAs and chromatin structure in plants. Newton Advanced Fellowship Research Fellow, The Royal Society, UK (105,500.00 GBP)

My Awards

  • 2019: Gender Equality Award. International Union of Immunological Societies (IUIS)
  • 2018: L’Oréal-UNESCO For Women In Science, International Rising Talents Fellow (15,000 euros)
  • 2016: L’Oréal-UNESCO-CONACYT-AMC Fellowship for Women in Science (Becas Para las Mujeres en la Ciencia) - Mexico ($100,000 MXN)
  • 2008-2011: UQ International Research Tuition Award (UQIRTA)
  • 2008-2011: Research Scholar scholarship from the Institute for Molecular Bioscience
  • 2006: ICE-EM International Travel Scholarship to attend the BioInfoSummer symposium at the Australian National University in Canberra ($2,500 AUD)

My Research Supervision


Supervision keywords


Areas of supervision

Genomics, Bioinformatics


Currently supervising

  • Irving Jair García (PhD candidate, based at the Advanced Genomics Unit, Cinvestav, Mexico - jointly advised with Dr. Stewart Gillmor)
  • Gabriel Martinez (MSc student, based at the Unidad Irapuato, Cinvestav, Mexico - jointly advised with Dr. Katarzyna Oktaba)

 

 

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Location

School of Biotechnology and Biomolecular Sciences
Room 220E, Level 2, Biological Science North Building (D26)
UNSW Sydney
NSW 2052 Australia

Videos

Long non-coding RNAs (lncRNAs) are prominent regulators of gene expression in eukaryotes, including plants and animals. It has been challenging to assess the functionality of the majority of lncRNAs; their rates of sequence divergence are much higher than those of protein-coding mRNAs, making it difficult to identify lncRNA conservation using traditional sequence comparison methods. To help identify functional RNAs, Selene’s group characterized the splicing conservation of lncRNAs in plants, specifically in 16 Brassica species. Our analysis revealed that 17.9% (112/627) of all intergenic lncRNAs display splicing conservation in at least one exon, which is substantially higher to previous estimates of lncRNA conservation in this group. Their findings agree with similar studies in vertebrates, demonstrating that splicing conservation can be evidence of selection. They provide evidence for the existence of evolutionary deeply conserved lncRNAs in plants.
Women in Bioinformatics & Data Science LA - Splicing conservation signals in plant non-coding RNAs
Entretien avec la chercheuse Selene Lizbeth Fernandez Valverde (Public Sénat - in french)