By Dr Therese Maria Becker

Journal articles

Pang TCY; Xu Z; Pothula S; Becker T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2017, 'Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research', Carcinogenesis, 38, pp. 588 - 591, http://dx.doi.org/10.1093/carcin/bgx030

Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, 18, http://dx.doi.org/10.3390/ijms18051047

Brungs D; Chen J; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2017, 'The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis', Oncotarget, 8, pp. 23099 - 23109, http://dx.doi.org/10.18632/oncotarget.15485

Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, 17, http://dx.doi.org/10.3390/ijms17081264

Brungs D; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2016, 'Gastric cancer stem cells: evidence, potential markers, and clinical implications', Journal of Gastroenterology, http://dx.doi.org/10.1007/s00535-015-1125-5

Tognela A; Spring KJ; Becker T; Caixeiro NJ; Bray VJ; Yip PY; Chua W; Lim SH; de Souza P, 2015, 'Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective', Critical Reviews in Oncology/Hematology, 93, pp. 90 - 102, http://dx.doi.org/10.1016/j.critrevonc.2014.10.001

Lim SHS; Becker TM; Chua W; Ng WL; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer', Journal of Clinical Pathology, 67, pp. 848 - 853, http://dx.doi.org/10.1136/jclinpath-2014-202499

Becker TM; Caixeiro NJ; Lim SH; Tognela A; Kienzle N; Scott KF; Spring KJ; De Souza P, 2014, 'New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use', International Journal of Cancer, 134, pp. 2523 - 2533, http://dx.doi.org/10.1002/ijc.28516

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; de Souza P; Becker TM, 2014, 'Circulating tumour cells-a bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-014-9502-8

Lim SH; Becker TM; Chua W; Caixeiro NJ; Ng WL; Kienzle N; Tognela A; Lumba S; Rasko JEJ; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer', Cancer Letters, 346, pp. 24 - 33, http://dx.doi.org/10.1016/j.canlet.2013.12.019

Rizos H; Menzies AM; Pupo GM; Carlino MS; Fung C; Hyman J; Haydu LE; Mijatov B; Becker TM; Boyd SC; Howle J; Saw R; Thompson JF; Kefford RF; Scolyer RA; Long GV, 2014, 'BRAF inhibitor resistance mechanisms in metastatic melanoma: Spectrum and clinical impact', Clinical Cancer Research, 20, pp. 1965 - 1977, http://dx.doi.org/10.1158/1078-0432.CCR-13-3122

Becker TM; Boyd SC; Mijatov B; Gowrishankar K; Snoyman S; Pupo GM; Scolyer RA; Mann GJ; Kefford RF; Zhang XD; Rizos H, 2014, 'Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor', ONCOGENE, 33, pp. 1158 - 1166, http://dx.doi.org/10.1038/onc.2013.45

Todd JR; Scurr LL; Becker TM; Kefford RF; Rizos H, 2014, 'The MAPK pathway functions as a redundant survival signal that reinforces the PI3K cascade in c-Kit mutant melanoma', ONCOGENE, 33, pp. 236 - 245, http://dx.doi.org/10.1038/onc.2012.562

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; De Souza P; Becker TM, 2014, 'Circulating tumour cells - A bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, 33, pp. 747 - 756, http://dx.doi.org/10.1007/s10555-014-9502-8

Carlino MS; Gowrishankar K; Saunders CAB; Pupo GM; Snoyman S; Zhang XD; Saw R; Becker TM; Kefford RF; Long GV; Rizos H, 2013, 'Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma', MOLECULAR CANCER THERAPEUTICS, 12, pp. 1332 - 1342, http://dx.doi.org/10.1158/1535-7163.MCT-13-0011

Todd JR; Becker TM; Kefford RF; Rizos H, 2013, 'Secondary c-Kit mutations confer acquired resistance to RTK inhibitors in c-Kit mutant melanoma cells', PIGMENT CELL & MELANOMA RESEARCH, 26, http://dx.doi.org/10.1111/pcmr.12107

Haferkamp S; Borst A; Adam C; Becker TM; Motschenbacher S; Windhoevel S; Hufnagel AL; Houben R; Meierjohann S, 2013, 'Vemurafenib Induces Senescence Features in Melanoma Cells', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133, pp. 1601 - 1609, http://dx.doi.org/10.1038/jid.2013.6

Boyd SC; Mijatov B; Pupo GM; Tran SL; Gowrishankar K; Shaw HM; Goding CR; Scolyer RA; Mann GJ; Kefford RF; Rizos H; Becker TM, 2013, 'Oncogenic B-RAFV(600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133, pp. 1269 - 1277, http://dx.doi.org/10.1038/jid.2012.421

Gowrishankar K; Snoyman S; Pupo GM; Becker TM; Kefford RF; Rizos H, 2013, 'Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition', Journal of Investigative Dermatology, 133, pp. 2493 - 2493, http://dx.doi.org/10.1038/jid.2013.125

Gowrishankar K; Snoyman S; Pupo GM; Becker TM; Kefford RF; Rizos H, 2012, 'Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 132, pp. 1850 - 1859, http://dx.doi.org/10.1038/jid.2012.63

Becker TM, 2012, 'Chromatin Remodeling in Carcinoma Cells', Reviews in Cell Biology and Molecular Medicine, http://dx.doi.org/10.1002/3527600906.mcb.201100031

Tran SL; Haferkamp S; Scurr LL; Gowrishankar K; Becker TM; Desilva C; Thompson JF; Scolyer RA; Kefford RF; Rizos H, 2012, 'Absence of distinguishing senescence traits in human melanocytic nevi', Journal of Investigative Dermatology, 132, pp. 2226 - 2234, http://dx.doi.org/10.1038/jid.2012.126

Scurr LL; McKenzie HA; Becker TM; Irvine M; Lai K; Mann GJ; Scolyer RA; Kefford RF; Rizos H, 2011, 'Selective loss of wild-type p16 ^INK4a expression in human nevi', Journal of Investigative Dermatology, 131, pp. 2329 - 2332, http://dx.doi.org/10.1038/jid.2011.197

Jiang CC; Lai F; Tay KH; Croft A; Rizos H; Becker TM; Yang F; Liu H; Thorne RF; Hersey P; Zhang XD, 2010, 'Apoptosis of human melanoma cells induced by inhibition of B-RAF ^V600E involves preferential splicing of bimS', Cell Death and Disease, 1, http://dx.doi.org/10.1038/cddis.2010.48

Becker TM; Philipsz S; Scurr LL; Fung C; Haferkamp S; Kefford RF; Rizos H, 2010, 'Oncogenic B-RAF(V600E) Promotes Anchorage-Independent Survival of Human Melanocytes', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, pp. 2144 - 2147, http://dx.doi.org/10.1038/jid.2010.117

McKenzie HA; Fung C; Becker TM; Irvine M; Mann GJ; Kefford RF; Rizos H, 2010, 'Predicting Functional Significance of Cancer-Associated p16(INK4a) Mutations in CDKN2A', HUMAN MUTATION, 31, pp. 692 - 701, http://dx.doi.org/10.1002/humu.21245

Zhang XD; Jiang CC; Lai F; Croft A; Tay KH; Thorne RF; Becker T; Rizos H; Hersey P, 2010, 'Abstract 1790: Apoptotic response of mutant B-RAF human melanoma cells to a B-RAF inhibitor involves increased splicing production of BimS', Cancer Research, 70, pp. 1790 - 1790, http://dx.doi.org/10.1158/1538-7445.am10-1790

Irvine M; Philipsz S; Frausto M; Mijatov B; Gallagher SJ; Fung C; Becker TM; Kefford RF; Rizos H, 2010, 'Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria', CELL CYCLE, 9, pp. 829 - 839, http://dx.doi.org/10.4161/cc.9.4.10785

Scurr LL; Pupo GM; Becker TM; Lai K; Schrama D; Haferkamp S; Irvine M; Scolyer RA; Mann GJ; Becker JC; Kefford RF; Rizos H, 2010, 'IGFBP7 Is Not Required for B-RAF-Induced Melanocyte Senescence', Cell, 141, pp. 717 - 727, http://dx.doi.org/10.1016/j.cell.2010.04.021

Haferkamp S; Scurr LL; Becker TM; Frausto M; Kefford RF; Rizos H, 2009, 'Oncogene-Induced Senescence Does Not Require the p16(INK4a) or p14ARF Melanoma Tumor Suppressors', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 129, pp. 1983 - 1991, http://dx.doi.org/10.1038/jid.2009.5

Haferkamp S; Tran SL; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'The relative contributions of the p53 and pRb pathways in oncogene induced melanocyte senescence', AGING-US, 1, pp. 542 - 556, http://dx.doi.org/10.18632/aging.100051

McKenzie H; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'Wild type and melanoma-associated mutant p16(INK4a) proteins do not oligomerize in vivo', PIGMENT CELL & MELANOMA RESEARCH, 22, pp. 131 - 133, http://dx.doi.org/10.1111/j.1755-148X.2008.00530.x

Becker TM; Haferkamp S; Dijkstra MK; Scurr LL; Frausto M; Diefenbach E; Scolyer RA; Reisman DN; Mann GJ; Kefford RF; Rizos H, 2009, 'The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)', MOLECULAR CANCER, 8, http://dx.doi.org/10.1186/1476-4598-8-4

Haferkamp S; Becker TM; Scurr LL; Kefford RF; Rizos H, 2008, 'p16(INK4a)-induced senescence is disabled by melanoma-associated mutations', AGING CELL, 7, pp. 733 - 745, http://dx.doi.org/10.1111/j.1474-9726.2008.00422.x

Rizos H; McKenzie HA; Ayub AL; Woodruff S; Becker TM; Scurr LL; Stahl J; Kefford RF, 2006, 'Physical and functional interaction of the p14(ARF) tumor suppressor with ribosomes', JOURNAL OF BIOLOGICAL CHEMISTRY, 281, pp. 38080 - 38088, http://dx.doi.org/10.1074/jbc.M609405200

Becker TM; Ayub AL; Kefford RF; Mann GJ; Rizos H, 2005, 'The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired', INTERNATIONAL JOURNAL OF CANCER, 117, pp. 569 - 573, http://dx.doi.org/10.1002/ijc.21265

Becker TM; Rizos H; de la Pena A; Leclercq IA; Woodruff S; Kefford RF; Mann GJ, 2005, 'Impaired inhibition of NF-kappa B activity by melanoma-associated p16INK4a mutations', BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 332, pp. 873 - 879, http://dx.doi.org/10.1016/j.bbrc.2005.05.032

Rizos H; Diefenbach E; Badhwar P; Woodruff S; Becker TM; Rooney RJ; Kefford RF, 2003, 'Association of p14(ARF) with the p120(E4F) transcriptional repressor enhances cell cycle inhibition', JOURNAL OF BIOLOGICAL CHEMISTRY, 278, pp. 4981 - 4989, http://dx.doi.org/10.1074/jbc.M210978200

Fung DCY; Holland EA; Becker TM; Hayward NK; Bressac-de Paillerets B; Mann GJ, 2003, 'eMelanoBase: an online locus-specific variant database for familial melanoma', Human Mutation, 21, pp. 2 - 7, http://dx.doi.org/10.1002/humu.10149

Becker TM; Rizos H; Kefford RF; Mann GJ, 2001, 'Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding', CLINICAL CANCER RESEARCH, 7, pp. 3282 - 3288, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000171574600046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Rizos H; Becker TM; Holland EA; Kefford RF; Mann GJ, 1997, 'Differential expression of p16(INK4a) and p16 beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations', ONCOGENE, 15, pp. 515 - 523, http://dx.doi.org/10.1038/sj.onc.1201217

Holland EA; Becker TM; Kefford RF; Mann GJ, 1997, 'Mutation analysis of CDKN2A and CDK4 in familial melanoma', Melanoma Research, 7, pp. S133 - S133, http://dx.doi.org/10.1097/00008390-199706001-00463

Holland EA; Beaton SC; Becker TM; Grulet OMC; Peters BA; Rizos H; Kefford RF; Mann GJ, 1995, 'Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds', Oncogene, 11, pp. 2288 - 2294

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