By Dr Tim Murphy

Journal articles

Kotsonis P; Murphy T; Majewski H, 1997, 'Determinants of the biological effects of phorbol esters: Neurotransmitter release', Proceedings of the Western Pharmacology Society, 40, pp. 155

Majewski H; Murphy T; Binko J, 1997, 'Sex hormones and nitric oxide vasodilator pathways', Proceedings of the Western Pharmacology Society, 40, pp. 142 - 143

Majewski H; Kotsonis P; Murphy TV; Barrington M, 1997, 'Noradrenaline release and the effect of endogenous activation of the phospholipase C/protein kinase C signalling pathway in rat atria', British Journal of Pharmacology, 121, pp. 1196 - 1202, http://dx.doi.org/10.1038/sj.bjp.0701236

Stoyanovsky D; Murphy T; Anno PR; Kim YM; Salama G, 1997, 'Nitric oxide activates skeletal and cardiac ryanodine receptors', Cell Calcium, 21, pp. 19 - 29, http://dx.doi.org/10.1016/S0143-4160(97)90093-2

Majewski H; Kotsonis P; Iannazzo L; Murphy TV; Musgrave IF, 1997, 'Protein kinase C and transmitter release', Clinical and Experimental Pharmacology and Physiology, 24, pp. 619 - 623, http://dx.doi.org/10.1111/j.1440-1681.1997.tb02102.x

Murphy TV; Broad LM; Garland CJ, 1995, 'Characterisation of inositol 1,4,5-trisphosphate binding sites in rabbit aortic smooth muscle', European Journal of Pharmacology: Molecular Pharmacology, 290, pp. 145 - 150, http://dx.doi.org/10.1016/0922-4106(95)90027-6

Murphy TV; Garland CJ, 1995, 'Specific accumulation of inositol 1,4,5-trisphosphate in rabbit basilar artery in response to noradrenaline but not 5-hydroxytryptamine', European Journal of Pharmacology: Molecular Pharmacology, 290, pp. 141 - 144, http://dx.doi.org/10.1016/0922-4106(95)90026-8

Seager JM; Murphy TV; Garland CJ, 1994, 'Importance of inositol (1,4,5)‐trisphosphate, intracellular Ca²⁺ release and myofilament Ca²⁺ sensitization in 5‐hydroxytryptamine‐evoked contraction of rabbit mesenteric artery', British Journal of Pharmacology, 111, pp. 525 - 532, http://dx.doi.org/10.1111/j.1476-5381.1994.tb14769.x

Murphy TV; Cross KML; Dunning PM; Garland CJ, 1994, 'Phorbol esters impair endothelium-dependent and independent relaxation in rat aortic rings', General Pharmacology, 25, pp. 581 - 588, http://dx.doi.org/10.1016/0306-3623(94)90218-6

Murphy TV; Foucart S; Majewski H, 1992, 'Prejunctional α2‐adrenoceptors in mouse atria function through G‐proteins which are sensitive to N‐ethylmaleimide, but not pertussis toxin', British Journal of Pharmacology, 106, pp. 871 - 876, http://dx.doi.org/10.1111/j.1476-5381.1992.tb14427.x

Murphy TV; Majewski H, 1990, 'Pertussis toxin differentiates between angiotensin II and β-adrenoceptor mediated facilitation of [³H]noradrenaline release from rat kidney slices', European Journal of Pharmacology, 183, pp. 1485 - 1486, http://dx.doi.org/10.1016/0014-2999(90)94632-8

Murphy TV; Majewski H, 1990, 'Pertussis toxin differentiates between α1- and α2-adrenoceptor-mediated inhibition of noradrenaline release from rat kidney cortex', European Journal of Pharmacology, 179, pp. 435 - 439, http://dx.doi.org/10.1016/0014-2999(90)90185-9

Murphy TV; Majewski H, 1990, 'PERTUSSIS TOXIN ATTENUATES ANGIOTENSIN II BUT NOT β‐ADRENOCEPTOR FACILITATION OF NORADRENALINE RELEASE FROM RAT KIDNEY CORTEX', Clinical and Experimental Pharmacology and Physiology, 17, pp. 521 - 526, http://dx.doi.org/10.1111/j.1440-1681.1990.tb01352.x

Foucart S; Murphy TV; Majewski H, 1990, 'Prejunctional β-adrenoceptors, angiotensin II and neuropeptide Y receptors on sympathetic nerves in mouse atria are linked to N-ethylmaleimide-susceptible G-proteins', Journal of the Autonomic Nervous System, 30, pp. 221 - 232, http://dx.doi.org/10.1016/0165-1838(90)90253-F

MAJEWSKI H; COSTA M; FOUCART S; MURPHY TV; MUSGRAVE IF, 1990, 'Second Messengers Are Involved in Facilitatory but Not Inhibitory Receptor Actions at Sympathetic Nerve Endings', Annals of the New York Academy of Sciences, 604, pp. 266 - 275, http://dx.doi.org/10.1111/j.1749-6632.1990.tb31999.x

Murphy TV; Majewski H, 1989, 'Modulation of noradrenaline release in slices of rat kidney cortex through α1- and α2-adrenoceptors', European Journal of Pharmacology, 169, pp. 285 - 295, http://dx.doi.org/10.1016/0014-2999(89)90026-5

Majewski H; Murphy TV, 1989, 'Beta-adrenoceptor blockade and sympathetic neurotransmission in the pithed rat', Journal of Hypertension, 7, pp. 991 - 996, http://dx.doi.org/10.1097/00004872-198912000-00010

Conference Papers

Drimousis S; Markus I; Murphy T; Liu L, 2018, 'Modulation of tachykinin NK2 receptor expression and activity by sex hormones in the colon', in NEUROGASTROENTEROLOGY AND MOTILITY, WILEY, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000440928700056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Murphy TV; Saunders SL; Britton FC; Sandow SL; Wright SE, 2018, 'Beta₃-Adrenergic Receptors in the Rat Cremaster Muscle Artery', in Proceedings for Annual Meeting of The Japanese Pharmacological Society, Japanese Pharmacological Society, http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po2-3-13

Kerr PM; Wei R; Lunn SE; Gust SL; Classen B; Murphy TV; Sandow SL; Plane F, 2017, 'The Functional Contribution Of Myoendothelial Feedback To Arterial Tone Is Determined By The Nature Of The Vasoconstricion', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, IL, Chicago, presented at Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting, IL, Chicago, 22 April 2017 - 26 April 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000405986505412&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sandow SL; Jones NM; Nguyen HL; Ellinsworth D; Grayson TH; Grimley R; Dettrick A; Murphy TV, 2015, 'Endothelial BKCa, but not TRPV4 activity is altered in focal cerebral ischemic stroke', in Allen DG; Davey DF (ed.), Proceedings of the Australian Physiology Society, Australian Physiology Society, Hobart, pp. 59P - 59P, presented at Australian Physiology Society Meeting 2015, Hobart, 29 November 2015 - 02 December 2015, http://aups.org.au/Proceedings/46/59P/

Sandow SL; Hinkley V; Leader L; Grayson TH; Murphy TV, 2015, 'IKCa-IP3R myoendothelial microdomains in the uterine radial arteriole are present in normal, and absent in gestational and pre-eclamptic hypertensive pregnancies: Targets for therapy?', in Allen DG; Davey DF (ed.), Proceedings of the Australian Physiology Society, Australian Physiology Society, Hobart, pp. 122P - 122P, presented at Australian Physiology Society Conference 2015, Hobart, 29 November 2015 - 02 December 2015, http://aups.org.au/Proceedings/46/122P

Sandow SL; Jones NM; Nguyen HL; Grayson TH; Murphy TV, 2014, 'Acute hypoxia and focal cerebral ischemia result in endothelial BKCaα and β1 protein expression in intact adult rat middle cerebral artery endothelium', in Morris B (ed.), State of the Heart 2014, International Society of cardiovascular Pharmacotherapy, Adelaide, pp. 105 - 105, presented at Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy, Adelaide, 26 November 2014 - 28 November 2014, http://www.hbprca.com.au/wp-content/uploads/SoTH_Workbook_FINAL_lowRes.pdf

Sandow S; Jones NM; Nguyen HL; Grayson TH; Murphy T, 2014, 'Focal cerebral ischemia and acute hypoxia increase the expression of endothelial BKCa alpha and beta 1 protein in intact middle cerebral artery of the adult rat', in JOURNAL OF VASCULAR RESEARCH, KARGER, Banff, CANADA, pp. 122 - 122, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, Banff, CANADA, 07 September 2014 - 11 September 2014

Quek J; Boyd R; Ameer O; Murphy T; Phillips J, 2014, 'Altered structural and biomechanical properties of mesenteric resistance arteries in a rat model of cystic kidney disease', in JOURNAL OF VASCULAR RESEARCH, KARGER, CANADA, Banff, pp. 115 - 115, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, CANADA, Banff, 07 September 2014 - 11 September 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346236200097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Murphy T; Ivanov G; Senadheera S; Sandow S, 2014, 'Insulin increases IKCa expression and function in rat cremaster muscle arteries', in JOURNAL OF VASCULAR RESEARCH, KARGER, CANADA, Banff, pp. 37 - 37, presented at 11th International Symposium on Resistance Arteries from Molecular Machinery to Clinical Challenges, CANADA, Banff, 07 September 2014 - 11 September 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346236200030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Murphy TV; Kanagarajah A; Senadheera S; Sandow SL, 2013, 'TRPV4-mediated responses of the rat isolated cremaster muscle artery', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, MA, Boston, presented at Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), MA, Boston, 20 April 2013 - 24 April 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000319860504432&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Senadheera S; Kim Y; Toemoe S; Bertrand P; Kochukov MY; Murphy TV; Marrelli SP; Tare M; Sandow SL, 2011, 'TRPC3 channels facilitate K-Ca-mediated endothelial vasodilator activity in rat mesenteric artery', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, DC, Washington, presented at Experimental Biology Meeting 2011, DC, Washington, 09 April 2011 - 13 April 2011, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310708401110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Howitt L; Grayson TH; Morris MJ; Murphy TV, 2010, 'Increased NO-dependent dilation of rat arterioles in diet-induced obesity', in The FASEB Journal, Federation of American Societies for Experimental Biology, Anaheim, pp. lb537, presented at Experimental Biology 2010, Anaheim, 24 April 2010 - 28 April 2010, http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/lb537?sid=6b3bd795-96e3-4770-8453-f6e66991246f

Howitt L; Sandow SL; Grayson TH; Morris MJ; Murphy TV, 2009, 'Increased NO-dependent dilation of rat arterioles in diet-induced obesity', in Hypertension, Lippincott Williams & Wilkins, Sydney, Australia, pp. 1499 - 1499, presented at 31st Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia, Sydney, Australia, 01 December 2009 - 03 December 2009, http://dx.doi.org/10.1161/HYP.0b013e3181df4279

Howitt L; Sandow SL; Grayson TH; Morris MJ; Murphy TV; Howitt L, 2009, 'Diet-induced obesity does not alter BKCa-mediated responses in rat mid-cerebral arterioles', in Sandow SL; Wise L (ed.), Journal of Vascular Research, Karger, Basel, Switzerland, pp. 29 - 29, presented at 14th Australian and New Zealand Microcirculation Society Meeting, Queenstown, New Zealand, 25 August 2009 - 27 August 2009, http://www.karger.com/Article/Pdf/230992

Yang Y; Ella SR; Murphy TV; Grayson TH; Hwang YT; Haddock R; Peichun G; Andrew BP; Korthuis RJ; Davis MJ; Hill MA, 2009, 'Relative lack of β1-subunit-mediated regulation of BKCa in cremaster arteriolar smooth muscle', in The FASEB Journal, The Federation of American Societies for Experimental Biology, New Orleans, pp. 627.10, presented at Experimental Biology 2009, New Orleans, 18 April 2009 - 22 April 2009, http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/627.10?sid=e377dc8b-cb5c-4279-a3b3-6e7539d14737

Murphy TV; Thiyagarajan L, 2009, 'INCREASED INTRA-LUMINAL PRESSURE ALTERS BETA-ADRENOCEPTOR SIGNALLING IN ISOLATED ARTERIOLES FROM THE RAT CREMASTER MUSCLE', in Proceedings of the 2nd Workshop on Isolation and Integration in Embedded Systems, IIES`09, pp. 33 - 33

Murphy TV; Ellis Z; Howitt L; Morris MJ; Howitt L, 2008, 'Effect of diet-induced obesity on myogenic responses of arterioles from the rat cremaster muscle', in Hypertension, pp. 44 - 45, presented at *, -

Hill MA; Murphy TV; Sandow S; Triggle C, 2006, 'The microvasculature as a therapeutic target in diabetes: Possible influence of vascular heterogeneity', in ACTA Pharmacologica Sinica, ACTA Pharmacologica Sinica, Shanghai, Peoples R China

Hill MR; Sandow S; Ding H; Kotecha N; Murphy TV, 2005, 'Endothelium-smooth muscle communication in arterioles: Effect of myogenic tone', in Drug Development Research, Wiley-Liss, Hoboken, NJ, USA

Murphy TV; Kotecha N; Hill MA, 2002, 'Effect of increased myogenic tone on endothelium-dependent dilation of arterioles', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A79 - A79, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174533600441&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Murphy TV; Spurrell BE; Hill MA, 2002, 'Tyrosine phosphorylation pathways in myogenic constriction of arterioles', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A79 - A79, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000174533600442&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Murphy TV; Spurrell BE; Hill MA, 2001, 'Effect of cSrc inhibition on arteriolar myogenic responses and phosphotyrosine formation', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A41 - A41, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000167438100227&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Spurrell BE; Murphy TV; Hill MA, 2001, 'Tyrosine phosphorylation of MAP kinase following increased intraluminal pressure or epidermal growth factor in cannulated arterioles', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A43 - A43, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000167438100241&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

MURPHY TV; FOUCART S; MAJEWSKI H, 1990, 'N-ETHYLMALEIMIDE (NEM) ATTENUATES ALPHA-2-ADRENOCEPTOR INHIBITION OF [H-3] NORADRENALINE RELEASE FROM MOUSE ATRIA', in BLOOD VESSELS, KARGER, pp. 50 - 50, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1990DY75800066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations

Sandow SL; Nguyen HL; Ellinsworth DC; Grayson TH; Jones NM; Murphy TV, 2016, 'Increased BKCa and TRPV4 expression, and decreased caveolae density in distal middle cerebral artery endothelium and smooth muscle in focal cerebral ischemic stroke', presented at Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, 07 December 2016 - 10 December 2016

Sandow SL; Lucque N; Nguyen HL; Grayson TH; Russell FD; Hinkley V; Jones NM; Murphy TV, 2016, 'Ischemic stroke results in loss of cerebral artery endothelial and smooth muscle connexin (Cx) 37, and altered expression of Cx40, but not Cxs32 and 43', presented at Joint meeting of the Australian Vascular Biology and Atherosclerosis Societies and High Blood Pressure Research Council, Hobart, 07 December 2016 - 10 December 2016

Sandow SL; Jones NM; Nguyen HL; Ellinsworth D; Grayson TH; Grimley R; Dettrick A; Murphy TV, 2015, 'Focal cerebral ischemic stroke results in endothelial BKCa expression and altered function, with no change in TRPV4 function, in middle cerebral artery', presented at Proceedings of the World Congress for Microcirculation, Kyoto, 25 September 2015 - 27 September 2015

Sandow SL; Jones NM; Nguyen HL; Grayson TH; Murphy TV, 2014, 'Acute hypoxia and focal cerebral ischemia result in endothelial BKCaα and β1 protein expression in intact adult rat middle cerebral artery endothelium.', presented at Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy, Adelaide, 26 November 2014 - 28 November 2014, http://www.hbprca.com.au/wp-content/uploads/SoTH_Workbook_FINAL_lowRes.pdf

Conference Abstracts

Murphy TV; Perry MA; Ulman LG; Marden NA; Daniel B; Hanna G; Housley GD, 2022, 'Microvascular anatomy and physiology laboratory class using the Australian cane toad', in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36, http://dx.doi.org/10.1096/fasebj.2022.36.S1.0R828

Murphy T; Wu L; Sandow S; Das A; Naim H, 2020, 'Effect of Dietary Nicotinamide Mononucleotide (NMN) on Function and Mechanics of Skeletal Muscle Arteries from Aged Mice', in FASEB JOURNAL, WILEY, CA, San Diego, Vol. 34, presented at Annual Meeting on Experimental Biology, CA, San Diego, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.04752

Murphy TV; Kanagarajah A; Toemoe S; Bertrand PP; Grayson TH; Britton FC; Leader L; Senadheera S; Sandow SL, 2016, 'TRPV3 control of uterine blood vessels', in ASCEPT-MPGPCR Book of Oral Abstracts, ASCEPT ASM, Melbourne, Vol. 413, pp. 70 - 70, presented at Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and Molecular Pharmacology of GPCRs Joint Scientific Meeting, Melbourne, 27 November 2016 - 30 November 2016, http://www.asceptasm.com/wp-content/uploads/2016/11/ASCEPT-MPGPCR-Book-of-oral-abstracts-final-2.pdf

Murphy TV; Nguyen HL; Grayson TH; Jones NM; Sandow SL, 2016, 'Effect of focal cerebral ischemia on BKCa and TRPV4 in rat middle cerebral artery', in The FASEB Journal, Federation of American Societies for Experimental Biology, San Diego, Vol. 40, pp. 1275.6 - 1275.6, presented at Experimental Biology 2016 Meeting, San Diego, 02 April 2016 - 06 April 2016, http://dx.doi.org/10.1096/fj.1530-6860

Phillips JK; Quek KJ; Boyd R; Ameer OZ; Murphy T, 2014, 'HIGH BLOOD PRESSURE AS A DRIVER OF STRUCTURAL AND BIOMECHANICAL CHANGES IN MESENTERIC RESISTANCE ARTERIES IN CHRONIC KIDNEY DISEASE', in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, AUSTRALIA, Adelaide, Vol. 65, pp. E39 - E40, presented at 36th Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia (HBPRCA), AUSTRALIA, Adelaide, 26 November 2014 - 28 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352490400059&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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