Keywords
Fields of Research (FoR)
Animal Cell and Molecular BiologyBiography
Dr Kaidonis is a Senior Post-doctoral Scientist at the Victor Chang Cardiac Research Institute. She is dedicated to understanding cardiac biology in two key areas: (i) perturbations in biochemical pathways that contribute to spontaneous coronary artery dissection, and (ii) changing biochemical pathways involved in cardiomyocyte maturation.
My Qualifications
Bachelor of Biomedical Science (The University of...view more
Dr Kaidonis is a Senior Post-doctoral Scientist at the Victor Chang Cardiac Research Institute. She is dedicated to understanding cardiac biology in two key areas: (i) perturbations in biochemical pathways that contribute to spontaneous coronary artery dissection, and (ii) changing biochemical pathways involved in cardiomyocyte maturation.
My Qualifications
Bachelor of Biomedical Science (The University of Adelaide)
Bachelor of Science Honours (The University of Adelaide)
Doctor of Philosophy (The University of Adelaide)
My Research Activities
Interrogating spontaneous coronary artery dissection-predisposing genetic variants
Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic acute coronary syndrome, predominantly affecting otherwise healthy women. We have identified a number of potential predisposing genetic variants that may contribute to SCAD and are now interrogating these to understand how they impact vascular structure and function to contribute to disease.
Understanding biochemical changes during cardiac development and repair
The ability of the heart to repair after injury is lost as the heart grows and matures. Our investigation into developmental changes in cardiomyocyte biochemistry has been used to provide insights into pathways that can be targeted so that regeneration can be enhanced after cardiac injury in adults. This work has led us to probe a number of proteins-of-interest that may be targets for cardiac repair.
My Research Supervision
Areas of supervision
Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic acute coronary syndrome, predominantly affecting otherwise healthy women. We have identified potentially predisposing genetic variants that may contribute to SCAD and are now interrogating these to understand how they impact vascular structure and function to contribute to disease. Projects investigating the impact of variants on protein localisation and function, as well as their role in vivo on vascular developmement, physiology, and response to vascular stressors, are available for ILP, honours, and HDR students.
Location
Level 5, 405 Liverpool St,
Darlinghurst, NSW, 2010