By Dr Yoshiro Okubo

Journal articles

Adachi N; Matsuura M; Okubo Y; Oana Y; Takei N; Kato M; Hara T; Onuma T, 2000, 'Predictive variables of interictal psychosis in epilepsy', Neurology, 55, pp. 1310 - 1314, http://dx.doi.org/10.1212/WNL.55.9.1310

Kikuchi M; Saito K; Watanabe A; Yamada K; Shibuya H; Nankai M; Kurumaji A; Hattori E; Ishiguro H; Shimizu H; Okubo Y; Toru M; Detera-Wadleigh SD; Yoshikawa T, 2000, 'Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples', American Journal of Medical Genetics - Neuropsychiatric Genetics, 96, pp. 477

Hara K; Terasaki O; Okubo Y, 2000, 'Dipole estimation of alpha EEG during alcohol ingestion in males genotypes for ALDH2', Life Sciences, 67, pp. 1163 - 1173, http://dx.doi.org/10.1016/S0024-3205(00)00707-4

Okubo Y; Suhara T; Suzuki K; Kobayashi K; Inoue O; Terasaki O; Someya Y; Sassa T; Sudo Y; Matsushima E; Iyo M; Tateno Y; Toru M, 2000, 'Serotonin 5-HT2 receptors in schizophrenic patients studied by positron emission tomography', Life Sciences, 66, pp. 2455 - 2464, http://dx.doi.org/10.1016/S0024-3205(00)80005-3

Kurumaji A; Nomoto H; Yoshikawa T; Okubo Y; Toru M, 2000, 'An association study between two missense variations of the benzodiazepine receptor (peripheral) gene and schizophrenia in a Japanese sample', Journal of Neural Transmission, 107, pp. 491 - 500, http://dx.doi.org/10.1007/s007020070090

Matsuura M; Adachi N; Oana Y; Okubo Y; Hara T; Onuma T, 2000, 'Proposal for a New Five-Axis Classification Scheme for Psychoses of Epilepsy', Epilepsy and Behavior, 1, pp. 343 - 352, http://dx.doi.org/10.1006/ebeh.2000.0113

Someya Y; Obata T; Suhara T; Ota Y; Ikehira H; Tanada S; Hirakawa K; Okubo Y; Sasaki Y, 2000, 'Seizure frequency and bilateral temporal abnormalities: A proton magnetic resonance spectroscopy of temporal lobe epilepsy', Seizure, 9, pp. 274 - 279, http://dx.doi.org/10.1053/seiz.2000.0396

Bergström KA; Halldin C; Savonen A; Okubo Y; Hiltunen J; Nobuhara K; Swahn CG; Karlsson P; McPherson D; Knapp FF; Larsson S; Schnell PO; Farde L, 1999, 'Iodine-123 labelled Z-(R,R)-IQNP: A potential radioligand for visualization of M1 and M2 muscarinic acetylcholine receptors in Alzheimer's disease', European Journal of Nuclear Medicine, 26, pp. 1482 - 1485, http://dx.doi.org/10.1007/s002590050482

Hirai N; Uchida S; Maehara T; Okubo Y; Shimizu H, 1999, 'Beta-1 (10-20 Hz) cortical oscillations observed in the human medial temporal lobe', NeuroReport, 10, pp. 3055 - 3059, http://dx.doi.org/10.1097/00001756-199909290-00033

Hirai N; Uchida S; Maehara T; Okubo Y; Shimizu H, 1999, 'Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe', Neuroscience, 90, pp. 1149 - 1155, http://dx.doi.org/10.1016/S0306-4522(98)00513-2

Sudo Y; Suhara T; Suzuki K; Okubo Y; Yoshikawa K; Uchida S; Sassa T; Okauchi T; Sasaki Y; Matsushita M, 1999, 'Muscarinic receptor occupancy by biperiden in living human brain', Life Sciences, 64, pp. PL99 - PL104, http://dx.doi.org/10.1016/S0024-3205(98)00613-4

Suhara T; Sudo Y; Okauchi T; Maeda J; Kawabe K; Suzuki K; Okubo Y; Nakashima Y; Ito H; Tanada S; Halldin C; Farde L, 1999, 'Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET', International Journal of Neuropsychopharmacology, 2, pp. 73 - 82, http://dx.doi.org/10.1017/S1461145799001431

Ito H; Okubo Y; Halldin C; Farde L, 1999, 'Mapping of central D2 dopamine receptors in man using [¹¹C]raclopride: PET with anatomic standardization technique', NeuroImage, 9, pp. 235 - 242, http://dx.doi.org/10.1006/nimg.1998.0401

Helfenbein J; Sandell J; Halldin C; Chalon S; Emond P; Okubo Y; Chou YH; Frangin Y; Douziech L; Gareau L; Swahn CG; Besnard JC; Farde L; Guilloteau D, 1999, 'PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter', Nuclear Medicine and Biology, 26, pp. 491 - 499, http://dx.doi.org/10.1016/S0969-8051(99)00004-9

Okubo Y; Olsson H; Ito H; Lofti M; Suhara T; Halldin C; Farde L, 1999, 'PET mapping of extrastriatal D2-like dopamine receptors in the human brain using an anatomic standardization technique and [¹¹C]FLB 457', NeuroImage, 10, pp. 666 - 674, http://dx.doi.org/10.1006/nimg.1999.0502

Ishiguro H; Ohtsuki T; Toru M; Itokawa M; Aoki J; Shibuya H; Kurumaji A; Okubo Y; Iwawaki A; Ota K; Shimizu H; Hamaguchi H; Arinami T, 1998, 'Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia', Neuroscience Letters, 257, pp. 45 - 48, http://dx.doi.org/10.1016/S0304-3940(98)00797-6

Suhara T; Sudo Y; Yoshida K; Okubo Y; Fukuda H; Obata T; Yoshikawa K; Suzuki K; Sasaki Y, 1998, 'Lung as reservoir for antidepressants in pharmacokinetic drug interactions', Lancet, 351, pp. 332 - 335, http://dx.doi.org/10.1016/S0140-6736(97)07336-4

Nyberg S; Nilsson U; Okubo Y; Halldin C; Farde L, 1998, 'Implications of brain imaging for the management of schizophrenia', International Clinical Psychopharmacology, 13, http://dx.doi.org/10.1097/00004850-199803003-00003

Sudo Y; Suhara T; Honda Y; Nakajima T; Okubo Y; Suzuki K; Nakashima Y; Yoshikawa K; Okauchi T; Sasaki Y; Matsushita M, 1998, 'Muscarinic cholinergic receptors in human narcolepsy: A PET study', Neurology, 51, pp. 1297 - 1302, http://dx.doi.org/10.1212/WNL.51.5.1297

Okubo Y; Suhara T; Suzuki K; Kobayashi K; Inoue O; Terasaki O; Someya Y; Sassa T; Sudo Y; Matsushima E; Iyo M; Tateno Y; Toru M, 1997, 'Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET', Nature, 385, pp. 634 - 635, http://dx.doi.org/10.1038/385634a0

Yana K; Mizuta H; Kawachi K; Yoshida H; Iida K; Okubo Y; Tohru M; Okuyama F, 1997, 'Decision support for psychiatric diagnosis based on a simple questionnaire', Methods of Information in Medicine, 36, pp. 349 - 351, http://dx.doi.org/10.1055/s-0038-1636858

Okubo Y; Suhara T; Sudo Y; Toru M, 1997, 'Possible role of dopamine D1 receptors in schizophrenia', Molecular Psychiatry, 2, pp. 291 - 292, http://dx.doi.org/10.1038/sj.mp.4000281

Koyama K; Hirasawa H; Okubo Y; Karasawa A, 1997, 'Quantitative EEG Correlates of Normal Aging in the Elderly', Clinical EEG and Neuroscience, 28, pp. 160 - 165, http://dx.doi.org/10.1177/155005949702800308

Nagase Y; Okubo Y; Toru M, 1996, 'Electroencephalography in schizophrenic patients: Comparison between neuroleptic-naive state and after treatment', Biological Psychiatry, 40, pp. 452 - 456, http://dx.doi.org/10.1016/0006-3223(96)00304-6

Okubo Y; Matsuura M; Asai T; Asai K; Kato M; Kojima T; Toru M, 1994, 'Epileptiform EEG Discharges in Healthy Children: Prevalence, Emotional and Behavioral Correlates, and Genetic Influences', Epilepsia, 35, pp. 832 - 841, http://dx.doi.org/10.1111/j.1528-1157.1994.tb02520.x

Nagase Y; Terasaki O; Okubo Y; Matsuura M; Toru M, 1994, 'Lower Interhemispheric Coherence in a Case of Agenesis of the Corpus Callosum', Clinical EEG and Neuroscience, 25, pp. 36 - 39, http://dx.doi.org/10.1177/155005949402500110

Terasaki O; Okubo Y; Matsuura M; Toru M; He Y; Hou Y; Shen Y, 1993, 'A quantitative study on the stationarity of EEGs of schizophrenics by a locally stationary autoregressive model', Neurology Psychiatry and Brain Research, 1, pp. 181 - 185

Matsuura M; Okubo Y; Toru M; Kojima T; He Y; Shen Y; Kyoon Lee C, 1993, 'A cross-national EEG study of children with emotional and behavioral problems: A WHO collaborative study in the Western Pacific region', Biological Psychiatry, 34, pp. 59 - 65, http://dx.doi.org/10.1016/0006-3223(93)90257-E

Matsuura M; Okubo Y; Kojima T; Takahashi R; Wang Y; Shen Y; Lee CK, 1993, 'A Cross‐National Prevalence Study of Children with Emotional and Behavioural Problems—A WHO Collaborative Study in the Western Pacific Region', Journal of Child Psychology and Psychiatry, 34, pp. 307 - 315, http://dx.doi.org/10.1111/j.1469-7610.1993.tb00994.x

Okubo Y; Matsuura M; Asai T; Asai K; Kato M; Kojima T; Toru M, 1993, 'A follow-up study of healthy children with epileptiform EEG discharges', Journal of Epilepsy, 6, pp. 250 - 256, http://dx.doi.org/10.1016/0896-6974(93)90010-8

Matsuura M; Senzaki A; Terasaki O; Ohbayashi S; Matsushima E; Okubo Y; Toru M, 1993, 'Classification of the Clinical Course of Delusional and/or Hallucinatory States in Epilepsy', Psychiatry and Clinical Neurosciences, 47, pp. 363 - 365, http://dx.doi.org/10.1111/j.1440-1819.1993.tb02107.x

Senzaki A; Okubo Y; Abe T; Matsuura M; Moriiwa M; Asai K; Toru M, 1993, 'Quantitative magnetic resonance imaging in patients with temporal lobe epilepsy', Journal of Epilepsy, 6, pp. 243 - 249, http://dx.doi.org/10.1016/0896-6974(93)90009-Y

Nagase Y; Okubo Y; Matsuura M; Kojima T; Toru M, 1992, 'EEG coherence in unmedicated schizophrenic patients: Topographical study of predominantly never medicated cases', Biological Psychiatry, 32, pp. 1028 - 1034, http://dx.doi.org/10.1016/0006-3223(92)90064-7

Nagase Y; Okubo Y; Matsuura M; Kojima T, 1992, 'Topographical changes in alpha power in medicated and unmedicated schizophrenics during digits span reverse matching test', Biological Psychiatry, 32, pp. 870 - 879, http://dx.doi.org/10.1016/0006-3223(92)90176-Z

Okubo Y; Komiyama M; Nakane Y; Takahashi T; Yamashita I; Nishizono M; Takahashi R, 1992, 'Collaborative Multicenter Field Trial of the Draft of ICD‐10 in Japan ––– Interdiagnostician Reliability and Disagreement: A Report from the WHO Project on “Field Trials of ICD‐10, Chapter V”', Psychiatry and Clinical Neurosciences, 46, pp. 23 - 35, http://dx.doi.org/10.1111/j.1440-1819.1992.tb00816.x

Senzaki A; Asai K; Okubo Y; Matsuura M; Moriiwa M; Kojima T; Toru M, 1991, 'Social Adjustment of Epileptic Patients with Psychiatric Symptoms', Psychiatry and Clinical Neurosciences, 45, pp. 490 - 492, http://dx.doi.org/10.1111/j.1440-1819.1991.tb02530.x

Semba J; Nankai M; Okubo Y; Kato M; Matsuura M; Takahashi R, 1990, 'Neuroendocrinological Effects of L‐Threo‐3, 4‐Dihydroxyphenylserine (DOPS), a Putative Norepinephrine Precursor, on Healthy Volunteers', Psychiatry and Clinical Neurosciences, 44, pp. 73 - 78, http://dx.doi.org/10.1111/j.1440-1819.1990.tb00443.x

Matsuura M; Okubo Y; Kato M; Kojima T; Takahashi R; Asai K; Asai T; Endo T; Yamada S; Nakane A; Kimura K; Suzuki M, 1989, 'An epidemiological investigation of emotional and behavioural problems in primary school children in Japan - The report of the first phase of a WHO collaborative study in Western Pacific Region', Social Psychiatry and Psychiatric Epidemiology, 24, pp. 17 - 22, http://dx.doi.org/10.1007/BF01788195

Kato M; Matsuura M; Okubo Y; Uesugi S; Moriiwa M; Kojima T; Takahashi R; Suzuki H; Ogiso M; Iwakawa Y; Shimazono Y, 1987, 'A Clinicoelectroencephalographic Study of Children with and without Seizures Showing Rolandic Discharge in their EEGs', Psychiatry and Clinical Neurosciences, 41, pp. 453 - 454, http://dx.doi.org/10.1111/j.1440-1819.1987.tb01724.x

Okubo Y; Matsuura M; Kato M; Uesugi H; Moriiwa M; Kojima T; Takahashi R; Asai K; Asai T; Shimazono Y, 1987, 'A Study of Healthy Children Showing Epileptiform Discharges in their EEGs', Psychiatry and Clinical Neurosciences, 41, pp. 459 - 460, http://dx.doi.org/10.1111/j.1440-1819.1987.tb01727.x

Matsuura M; Yamamoto K; Fukuzawa H; Okubo Y; Uesugi H; Moriiwa M; Kojima T; Shimazono Y, 1985, 'Age development and sex differences of various EEG elements in healthy children and adults - Quantification by a computerized wave form recognition method', Electroencephalography and Clinical Neurophysiology, 60, pp. 394 - 406, http://dx.doi.org/10.1016/0013-4694(85)91013-2

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