By Emeritus Professor Ian William Dawes

Journal articles

Tsoi BM; Beckhouse AG; Gelling CL; Raftery MJ; Chiu J; Tsoi AM; Lauterbach L; Rogers PL; Higgins VJ; Dawes IW, 2009, 'Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae', The Journal of Biological Chemistry, 284, pp. 11205 - 11215

Tang BMP; Mclean AS; Dawes IW; Huang SJ; Lin RC, 2009, 'Gene-expression profiling of peripheral blood mononuclear cells in sepsis', Critical Care Medicine, 37, pp. 2324

Thorsen M; Perrone G; Kristiansson E; Traini M; Ye T; Dawes IW; Nerman O; Tamas M, 2009, 'Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae', BMC Genomics, 10

Tay CY; Mitchell HM; Dong Q; Goh K; Dawes IW; Lan R, 2009, 'Population structure of Helicobacter pylori among ethnic groups in Malaysia: Recent acquisition of the bacterium by the Malay population', BMC Microbiology, 9, pp. 126, http://dx.doi.org/10.1186/1471-2180-9-126

Chen AK; Gelling CL; Rogers PL; Dawes IW; Rosche B, 2009, 'Response of Saccharomyces cerevisiae to stress-free acidification', Journal of Microbiology, 47, pp. 1 - 8, http://dx.doi.org/10.1007/s12275-008-0167-2

Victoria JG; Beckhouse AG; Victoria L; Eric JB; Rogers PJ; Dawes IW; Higgins VJ, 2009, 'Zinc starvation induces a stress response in Saccharomyces cerevisiae that is mediated by the Msn2p and Msn4p transcriptional activators.', FEMS Yeast Research, 9, pp. 1187 - 1195, http://dx.doi.org/10.1111/j.1567-1364.2009.00557.x

Ng CH; Tan S; Perrone G; Thorpe GW; Higgins VJ; Dawes IW, 2008, 'Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: The role of NADPH-generating systems and the SKN7 transcription factor', Free Radical Biology and Medicine, 44, pp. 1131 - 1145, http://dx.doi.org/10.1016/j.freeradbiomed.2007.12.008

Low C; Shui G; Liew L; Buttner S; Madeo F; Dawes IW; Wenk M; Yang H, 2008, 'Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast', Journal of Cell Science, 121, pp. 2671 - 2684, http://dx.doi.org/10.1242/jcs.028977

Tang B; McLean A; Dawes IW; Huang SJ; Cowley MJ; Lin RC, 2008, 'Gene-expression profiling of Gram-positive and Gram-negative sepsis in critically ill patients', Critical Care Medicine, 36, pp. 1125 - 1128, http://dx.doi.org/10.1097/CCM.0b0013e3181692c0b

Dilda P; Perrone G; Philp A; Lock RB; Dawes IW; Hogg PJ, 2008, 'Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid', International Journal of Biochemistry and Cell Biology, 40, pp. 1016 - 1029, http://dx.doi.org/10.1016/j.biocel.2007.11.002

Gelling CL; Dawes IW; Richhardt N; Lill R; Muhlenhoff U, 2008, 'Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes', Molecular and Cellular Biology, 28, pp. 1851 - 1861, http://dx.doi.org/10.1128/MCB.01963-07

Fong C; Temple MD; Alic N; Chiu II; Durchdewald M; Thorpe GW; Higgins VJ; Dawes IW, 2008, 'Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor', FEMS Yeast Research, 8, pp. 386 - 399, http://dx.doi.org/10.1111/j.1567-1364.2007.00349.x

Herst P; Perrone G; Dawes IW; Bircham P; Berridge M, 2008, 'Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits', FEMS Yeast Research, 8, pp. 897 - 905

Perrone G; Tan S; Dawes IW, 2008, 'Reactive oxygen species and yeast apoptosis', Biochimica et Biophysica ACTA - Molecular Cell Research, 1783, pp. 1354 - 1368

Chiu II; Tillett D; Dawes IW; March PE, 2008, 'Site-directed, Ligase-Independent Mutagenesis (SLIM) for highly efficient mutagenesis of plasmids greater than 8kb', Journal of Microbiological Methods, 73, pp. 195 - 198, http://dx.doi.org/10.1016/j.mimet.2008.02.013

Beckhouse AG; Grant CM; Rogers PJ; Dawes IW; Higgins VJ, 2008, 'The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors', FEMS Yeast Research, 8, pp. 1214 - 1222

Dawes IW; Kornfeld GD; Perrone G, 2007, 'Functional genomics in yeast', Microbiology Australia, 28, pp. 51 - 54

Stefani M; Markus MA; Lin RC; Dawes IW; Morris B, 2007, 'The effect of resveratrol on a cell model of human aging.', Annals of the New York Academy of Sciences, 1114, pp. 407 - 418

Tang BMP; McLean AS; Dawes IW; Huang SJ; Lin RCY, 2007, 'The use of gene-expression profiling to identify candidate genes in human sepsis', American Journal of Respiratory and Critical Care Medicine, 176, pp. 676 - 684

Lam YT; Temple MD; Suarna C; Stocker RC; Dawes IW, 2006, 'Effects of Antioxidants on yeast cell replicative ageing', Free Radical Research, 40, pp. S82 - S82

Trotter EW; Collinson EJ; Dawes IW; Grant CM, 2006, 'Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae', Applied and Environmental Microbiology, 72, pp. 4885 - 4892

Morris BJ; Stefani M; Markus MA; Pinese M; Lin RCY; Dawes IW, 2006, 'Resveratrol induces expression of genes beneficial to health of mortal human fibroblasts in culture.', Journal of Hypertension, 24, pp. 396

Cipak A; Hasslacher M; Tehlivets O; Collinson EJ; Zivkovic M; Matijevic T; Wonisch W; Waeg G; Dawes IW; Zarkovic N; Kohlwein S, 2006, 'Saccharomyces cerevisiae strain expressing a plant fatty acid desaturase produces polyunsaturated fatty acids and is susceptible to oxidative stress induced by lipid peroxidation', Free Radical Biology and Medicine, 40, pp. 897 - 906

Ng C; Dawes IW, 2006, 'The role of sumoylation in oxidative and other stress responses in the yeast, Saccharomyces cerevisae', Free Radical Research, 40, pp. S158 - S158

Temple MD; Perrone G; Dawes IW, 2005, 'Complex cellular responses to reactive oxygen species', Trends in Cell Biology, 15, pp. 319 - 326

Perrone G; Grant CM; Dawes IW, 2005, 'Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae', Molecular Biology of the Cell, 16, pp. 218 - 230

Drakulic T; Temple MD; Guido R; Jarolim S; Breitenbach M; Attfield P; Dawes IW, 2005, 'Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae', FEMS Yeast Research, 5, pp. 1215 - 1228

Dilda P; Don AS; Tanabe K; Higgins VJ; Allen JA; Dawes IW; Hogg PJ, 2005, 'Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains', Journal of the National Cancer Institute, 97, pp. 1539 - 1547

Park J; Collinson EJ; Grant CM; Dawes IW, 2005, 'Rom2p, the Rho1 GTP/GDP exchange factor of Saccharomyces cerevisiae,can mediate stress responses via the Ras-cAMP pathway', The Journal of Biological Chemistry, 280, pp. 2529 - 2535

Park J; Grant CM; Dawes IW, 2005, 'The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses', Biochemical and Biophysical Research Communications, 327, pp. 311 - 319, http://www.sciencedirect.com/science/article/B6WBK-4F1GN4P-9/2/6821613e5fe421bce6c6aa58fa8c4113

Thorpe GW; Fong C; Alic N; Higgins VJ; Dawes IW, 2004, 'Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 6564 - 6569

Tran N; Raponi M; Dawes IW; Arndt G, 2004, 'Control of specific gene expression in mammalian cells by co-expressionof long complementary RNAs', FEBS Letters, 573, pp. 127 - 134

Alic N; Felder T; Temple MD; Gloeckner C; Higgins VJ; Briza P; Dawes IW, 2004, 'Genome-wide transcriptional responses to a lipid hydroperoxide:Adaptation occurs without induction of oxidant defenses', Free Radical Biology and Medicine, 37, pp. 23 - 35

Gelling CL; Piper M; Hong SP; Kornfeld GD; Dawes IW, 2004, 'Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae', The Journal of Biological Chemistry, 279, pp. 7072 - 7081

Heeren G; Jarolim S; Laun P; Rinnerthaler M; Stolze K; Perrone G; Kohlwein S; Nohl H; Dawes IW; Breitenbach M, 2004, 'The role of respiration, reactive oxygen species and oxidative stressin mother cell-specific ageing of yeast strains defective in the RASsignalling pathway', FEMS Yeast Research, 5, pp. 157 - 167

Alic N; Higgins VJ; Pichova A; Breitenbach M; Dawes IW, 2003, 'Lipid Hydroperoxides Activate the Mitogen-activated Protein Kinase Mpk1p in Saccharomyces cerevisiae', Journal of Biological Chemistry, 278, pp. 41849 - 41855, http://dx.doi.org/10.1074/jbc.M307760200

Higgins VJ; Rogers PJ; Dawes IW, 2003, 'Application of genome-wide expression analysis to identify molecular markers useful in monitoring industrial fermentations', Applied and Environmental Microbiology, 69, pp. 7535 - 7540

Wheeler GL; Trotter EW; Dawes IW; Grant CM, 2003, 'Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors', The Journal of Biological Chemistry, 278, pp. 49920 - 49928

Tran N; Cairns MJ; Dawes IW; Arndt G, 2003, 'Expressing functional siRNAs in mammalian cells using convergent transcription', BMC Biotechnology, 3, pp. 1 - 9

Collins BM; Cubeddu L; Naidoo N; Harrop SJ; Kornfeld GD; Dawes IW; Curmi PM; Mabbutt BC, 2003, 'Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: crystal structure of an oligomeric complex of yeast SmF', The Journal of Biological Chemistry, 278, pp. 17291 - 17298

Poljak A; Dawes IW; Ingelse BA; Duncan MW; Smythe GA; Grant CM, 2003, 'Oxidative damage to proteins in yeast cells exposed to adaptive levels of H2O2', Redox Report, 8, pp. 371 - 377

Higgins VJ; Beckhouse AG; Oliver AD; Rogers PJ; Dawes IW, 2003, 'Yeast genome-wide expression analysis identifies a strong ergosterol and oxidative stress response during the initial stages of an industrial lager fermentation', Applied and Environmental Microbiology, 69, pp. 4777 - 4787

Day RE; Higgins VJ; Rogers PJ; Dawes IW, 2002, 'Characterisation of the putative maltose transporters encoded by YDL247w and YJR160c', Yeast, 19, pp. 1015 - 1027

Quinn KA; Perrone G; Dawes IW; Grant CM, 2002, 'Glutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor', Molecular Microbiology, 2, pp. 545 - 556

Day RE; Rogers PJ; Dawes IW; Higgins VJ, 2002, 'Molecular Analysis of Maltotriose Transport and Utilisation by Saccharomyces cerevisiae', Applied and Environmental Microbiology, 68, pp. 5326 - 5335

Higgins VJ; Alic N; Thorpe GW; Breitenbach M; Dawes IW; Larsson V, 2002, 'Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress', Yeast, 19, pp. 203 - 214

Perrone G; Quinn KA; Dawes IW; Grant CM; Shenton D, 2002, 'Regulation of Protein S-Thiolation by Glutaredoxin 5 in the Yeast Saccharomyces cerevisiae', Biological Chemistry, 277, pp. 16853 - 16859

Piper M; Dawes IW; Hong S, 2002, 'Regulation of the yeast glycine cleavage genes is responsive to the availability of multiple nutrients', FEMS Yeast Research, 2, pp. 59 - 71

Tait AS; Lopez JA; Dawes IW; Chong BH; Dong J, 2002, 'Site-directed mutagenesis of platelet glycoprotein Ib-alpha demonstrating residues involved in the sulfation of tyrosines 276, 278 and 279', Blood, 99, pp. 4422 - 4427

Briza P; Bogengruber E; Dawes IW; Breitenbach M, 2002, 'Systematic analysis of sporulation phenotypes in 624 non-lethal homozygous deletion strains of Saccharomyces cerevisiae', Yeast, 19, pp. 403 - 422

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