Select Publications

Journal articles

Dawes IW; Perrone GG, 2020, 'Stress and ageing in yeast', FEMS Yeast Research, vol. 20, http://dx.doi.org/10.1093/femsyr/foz085

Carmona-Gutierrez D; Bauer MA; Zimmermann A; Aguilera A; Austriaco N; Ayscough K; Balzan R; Bar-Nun S; Barrientos A; Belenky P; Blondel M; Braun RJ; Breitenbach M; Burhans WC; Büttner S; Cavalieri D; Chang M; Cooper KF; Côrte-Real M; Costa V; Cullin C; Dawes I; Dengjel J; Dickman MB; Eisenberg T; Fahrenkrog B; Fasel N; Fröhlich KU; Gargouri A; Giannattasio S; Goffrini P; Gourlay CW; Grant CM; Greenwood MT; Guaragnella N; Heger T; Heinisch J; Herker E; Herrmann JM; Hofer S; Jiménez-Ruiz A; Jungwirth H; Kainz K; Kontoyiannis DP; Ludovico P; Manon S; Martegani E; Mazzoni C; Megeney LA; Meisinger C; Nielsen J; Nyström T; Osiewacz HD; Outeiro TF; Park HO; Pendl T; Petranovic D; Picot S; Polčic P; Powers T; Ramsdale M; Rinnerthaler M; Rockenfeller P; Ruckenstuhl C; Schaffrath R; Segovia M; Severin FF; Sharon A; Sigrist SJ; Sommer-Ruck C; Sousa MJ; Thevelein JM; Thevissen K; Titorenko V; Toledano MB; Tuite M; Vögtle FN; Westermann B; Winderickx J; Wissing S; Wölfl S; Zhang ZJ; Zhao RY; Zhou B; Galluzzi L; Kroemer G; Madeo F, 2018, 'Guidelines and recommendations on yeast cell death nomenclature', Microbial Cell, vol. 5, pp. 4 - 31, http://dx.doi.org/10.15698/mic2018.01.607

Dawes IW, 2016, 'Ian dawes-the third pope-lucky to be a researcher', FEMS Yeast Research, vol. 16, pp. 1 - 8, http://dx.doi.org/10.1093/femsyr/fow040

Qi Y; Kapterian TS; Du X; Ma Q; Fei W; Zhang Y; Huang X; Dawes IW; Yang H, 2016, 'CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development', Journal of Lipid Research, vol. 57, pp. 767 - 780, http://dx.doi.org/10.1194/jlr.M060574

Andrisic L; Collinson EJ; Tehlivets O; Perak E; Zarkovic T; Dawes IW; Zarkovic N; Cipak Gasparovic A, 2014, 'Transcriptional and antioxidative responses to endogenous polyunsaturated fatty acid accumulation in yeast', Molecular and Cellular Biochemistry, http://dx.doi.org/10.1007/s11010-014-2229-6

Nair S; Traini M; Dawes IW; Perrone GG, 2014, 'Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: Importance of lipid homeostasis', Molecular Biology of the Cell, vol. 25, pp. 2235 - 2249, http://dx.doi.org/10.1091/mbc.E13-04-0216

Smethurst DGJ; Dawes IW; Gourlay CW, 2014, 'Actin - a biosensor that determines cell fate in yeasts', FEMS Yeast Research, vol. 14, pp. 89 - 95, http://dx.doi.org/10.1111/1567-1364.12119

Jarolim S; Ayer A; Pillay B; Gee AC; Phrakaysone A; Perrone GG; Breitenbach M; Dawes IW, 2013, 'Saccharomyces cerevisiae genes involved in survival of heat shock', G3: Genes, Genomes, Genetics, vol. 3, pp. 2321 - 2333, http://dx.doi.org/10.1534/g3.113.007971

Ayer A; Dawes IW; Gourlay CW, 2013, 'Cellular redox homeostasis, reactive oxygen species and replicative ageing in Saccharomyces cerevisiae', FEMS Yeast Research, vol. 14, pp. 60 - 72, http://dx.doi.org/10.1111/1567-1364.12114

Lee JC; Tsoi AM; Kornfeld GD; Dawes IW, 2013, 'Cellular responses to L-serine in Saccharomyces cerevisiae: roles of general amino acid control, compartmentalization and aspartate synthesis', FEMS Yeast Research, vol. 13, pp. 618 - 634, http://dx.doi.org/10.1111/1567-1364.12063

Ayer A; Sanwald J; Pillay B; Meyer AJ; Perrone G; Dawes IW, 2013, 'Distinct redox regulation in subcellular compartments in response to various stress conditions', PLoS ONE, vol. 8, pp. Article number e65240, http://dx.doi.org/10.1371/journal.pone.0065240

Aung-Htut MT; Lam YT; Lim YL; Rinnerthaler M; Gelling CL; Breitenbach M; Yang H; Dawes IW, 2013, 'Maintenance of mitochondrial morphology by autophagy and its role in high glucose effects on chronological lifespan of Saccharomyces cerevisiae', Oxidative Medicine and Cellular Longevity, vol. 2013, pp. 1 - 13, http://dx.doi.org/10.1155/2013/636287

Breitenbach M; Ralser M; Perrone G; Iglseder B; Rinnerthaler M; Dawes IW, 2013, 'Oxidative stress and neurodegeneration: the yeast model system', Frontiers in Bioscience, vol. 18, pp. 1174 - 1193, http://dx.doi.org/10.2741/4171

Thorpe GW; Reodica M; Davies MJ; Heeren G; Jarolim S; Pillay B; Breitenbach M; Higgins VJ; Dawes IW, 2013, 'Superoxide radicals have a protective role during H2O2 stress', Molecular Biology of the Cell, vol. 24, pp. 2876 - 2884, http://dx.doi.org/10.1091/mbc.E13-01-0052

Du X; Kazim AS; Dawes IW; Brown AJ; Yang H, 2013, 'The AAA ATPase VPS4/SKD1 regulates endosomal cholesterol trafficking independently of ESCRT-III.', Traffic, vol. 14, pp. 107 - 119, http://dx.doi.org/10.1111/tra.12015

Gelling CL; Dawes IW; Perlmutter DH; Fisher EA; Brodsky JL, 2012, 'The Endosomal protein-sorting receptor sortilin has a role in trafficking α-1 antitrypsin', Genetics, vol. 192, pp. 889 - 903, http://dx.doi.org/10.1534/genetics.112.143487

Ayer A; Fellermeier S; Li SS; Fife C; Smits G; Meyer AJ; Dawes IW; Perrone G; Fife CM, 2012, 'A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis', PLoS ONE, vol. 7, pp. e44278, http://dx.doi.org/10.1371/journal.pone.0044278

Gelling CL; Dawes IW; Perlmutter DH; Fisher EA; Brodsky JL, 2012, 'A yeast genome-wide screen reveals a role for the endosomal sorting receptor sortilin in trafficking alpha-1 antitrypsin', Genetics, vol. 192, pp. 889 - 903

Ta MT; Kapterian T; Fei W; Du X; Brown AJ; Dawes IW; Yang H, 2012, 'Accumulation of squalene is associated with the clustering of lipid droplets.', FEBS Journal, vol. 279, pp. 4231 - 4244, http://dx.doi.org/10.1111/febs.12015

Chiu J; Dawes IW, 2012, 'Redox control of cell proliferation', Trends in Cell Biology, vol. 22, pp. 592 - 601, http://dx.doi.org/10.1016/j.tcb.2012.08.002

Fei W; Shui G; Zhang Y; Krahmer N; Ferguson C; Kapterian T; Lin RCY; Dawes IW; Brown AJ; Li P; Huang X; Parton R; Wenk M; Walther TC; Yang H, 2011, 'A role for phosphatidic acid in the formation of “supersized” lipid droplets', PLOS Genetics, vol. 7, pp. e1002201 1 - e1002201 11, http://dx.doi.org/10.1371/journal.pgen.1002201

Wu MJ; O'Doherty PJ; Fernandez HR; Victoria L; Rogers PJ; Dawes IW; Higgins VJ, 2011, 'An antioxidant screening assay based on oxidant-induced cell cycle arrest in Saccharomyces cerevisiae.', FEMS Yeast Research, vol. 11, pp. 379 - 387, http://dx.doi.org/10.1111/j.1567-1364.2011.00726.x

Chiu J; Tactacan CM; Tan S; Lin RCY; Wouters MA; Dawes IW, 2011, 'Cell cycle sensing of oxidative stress in Saccharomyces cerevisiae by oxidation of a specific cysteine residue in the transcription factor Swi6p', The Journal of Biological Chemistry, vol. 286, pp. 5204 - 5214, http://dx.doi.org/10.1074/jbc.M110.172973

Lam YT; Aung MT; Lim YL; Yang H; Dawes IW, 2011, 'Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells', Free Radical Biology and Medicine, vol. 50, pp. 963 - 970, http://dx.doi.org/10.1016/j.freeradbiomed.2011.01.013

Collinson EJ; Wimmer-Kleikamp S; Gerega SK; Yang YH; Parish CR; Dawes IW; Stocker R, 2011, 'The yeast homolog of heme oxygenase-1 affords cellular antioxidant protection via the transcriptional regulation of known antioxidant genes.', The Journal of Biological Chemistry, vol. 286, pp. 2205 - 2214, http://dx.doi.org/10.1074/jbc.M110.187062

Lin RCY; Weeks KL; Gao XM; Williams RBH; Bernardo BC; Kiriazis H; Matthews VB; Woodcock EA; Bouwman RD; Mollica JP; Speirs HJ; Dawes IW; Daly RJ; Shioi T; Izumo S; Febbraio MA; Du X; McMullen JR, 2010, 'PI3K(p110á) protects against myocardial infarction-induced heart failure: Identification of PI3K-regulated miRNAs and mRNAs', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 30, pp. 724 - 732, http://dx.doi.org/10.1161/ATVBAHA.109.201988

Klinger H; Rinnerthaler M; Lam YT; Laun P; Heeren G; Klinger H; Dickinson JR; Dawes IW; Breitenbach M, 2010, 'Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells', Experimental Gerontology, vol. 45, pp. 533 - 542, http://dx.doi.org/10.1016/j.exger.2010.03.016

Ayer A; Tan S; Grant CM; Meyer AJ; Dawes IW; Perrone G, 2010, 'The critical role of glutathione in maintenance of the mitochondrial genome', Free Radical Biology and Medicine, vol. 49, pp. 1956 - 1968, http://dx.doi.org/10.1016/j.freeradbiomed.2010.09.023

Lam YT; Stocker R; Dawes IW, 2010, 'The lipophilic antioxidants alpha-tocopherol and coenzyme Q10 reduce the replicative lifespan of Saccharomyces cerevisiae', Free Radical Biology and Medicine, vol. 49, pp. 237 - 244, http://dx.doi.org/10.1016/j.freeradbiomed.2010.04.008

Tan S; Greetham D; Raeth S; Grant CM; Dawes IW; Perrone G; Raeth S, 2010, 'The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae', The Journal of Biological Chemistry, vol. 285, pp. 6118 - 6126, http://dx.doi.org/10.1074/jbcM109.062844

Greetham D; Vickerstaff J; Shenton D; Perrone G; Dawes IW; Grant CM, 2010, 'Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae', BMC Biochemistry, vol. 11, http://dx.doi.org/10.1186/1471-2091-11-3

Tang BMP; McLean AS; Dawes IW; Huang SJ; Lin RCY, 2009, 'Gene-expression profiling of peripheral blood mononuclear cells in sepsis', Critical Care Medicine, vol. 37, pp. 882 - 888, http://dx.doi.org/10.1097/CCM.0b013e31819b52fd

Gurvitz A; Suomi F; Rottensteiner H; Hiltunen J; Dawes IW, 2009, 'Avoiding unscheduled transcription in shared promoters: Saccharomyces cerevisiae Sum1p represses the divergent gene pair SPS18-SPS19 through a midsporulation element (MSE)', FEMS Yeast Research, vol. 9, pp. 821 - 831, http://dx.doi.org/10.1111/j.1567-1364.2009.00527.x

Tan S; Teo M; Lam YT; Dawes IW; Perrone G, 2009, 'Cu, Zn superoxide dismutase and NADP(H)homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae', Molecular Biology of the Cell, vol. 20, pp. 1493 - 1508, http://dx.doi.org/10.1091/mbc.E08-07-0697

Tsoi BM; Beckhouse AG; Gelling CL; Raftery MJ; Chiu J; Tsoi AM; Lauterbach L; Rogers PL; Higgins VJ; Dawes IW, 2009, 'Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae', The Journal of Biological Chemistry, vol. 284, pp. 11205 - 11215, http://dx.doi.org/10.1074/jbc.M809225200

Tang BMP; Mclean AS; Dawes IW; Huang SJ; Lin RC, 2009, 'Gene-expression profiling of peripheral blood mononuclear cells in sepsis', Critical Care Medicine, vol. 37, pp. 2324, http://dx.doi.org/10.1097/CCM.0b013e3181a9ef74

Thorsen M; Perrone G; Kristiansson E; Traini M; Ye T; Dawes IW; Nerman O; Tamas M, 2009, 'Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae', BMC Genomics, vol. 10, http://dx.doi.org/10.1186/1471-2164-10-105

Tay CY; Mitchell HM; Dong Q; Goh K; Dawes IW; Lan R, 2009, 'Population structure of Helicobacter pylori among ethnic groups in Malaysia: Recent acquisition of the bacterium by the Malay population', BMC Microbiology, vol. 9, pp. 126, http://dx.doi.org/10.1186/1471-2180-9-126

Chen AK; Gelling CL; Rogers PL; Dawes IW; Rosche B, 2009, 'Response of Saccharomyces cerevisiae to stress-free acidification', Journal of Microbiology, vol. 47, pp. 1 - 8, http://dx.doi.org/10.1007/s12275-008-0167-2

Victoria JG; Beckhouse AG; Victoria L; Eric JB; Rogers PJ; Dawes IW; Higgins VJ, 2009, 'Zinc starvation induces a stress response in Saccharomyces cerevisiae that is mediated by the Msn2p and Msn4p transcriptional activators.', FEMS Yeast Research, vol. 9, pp. 1187 - 1195, http://dx.doi.org/10.1111/j.1567-1364.2009.00557.x

Ng CH; Tan S; Perrone G; Thorpe GW; Higgins VJ; Dawes IW, 2008, 'Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: The role of NADPH-generating systems and the SKN7 transcription factor', Free Radical Biology and Medicine, vol. 44, pp. 1131 - 1145, http://dx.doi.org/10.1016/j.freeradbiomed.2007.12.008

Low C; Shui G; Liew L; Buttner S; Madeo F; Dawes IW; Wenk M; Yang H, 2008, 'Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast', Journal of Cell Science, vol. 121, pp. 2671 - 2684, http://dx.doi.org/10.1242/jcs.028977

Tang B; McLean A; Dawes IW; Huang SJ; Cowley MJ; Lin RC, 2008, 'Gene-expression profiling of Gram-positive and Gram-negative sepsis in critically ill patients', Critical Care Medicine, vol. 36, pp. 1125 - 1128, http://dx.doi.org/10.1097/CCM.0b0013e3181692c0b

Dilda P; Perrone G; Philp A; Lock RB; Dawes IW; Hogg PJ, 2008, 'Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid', International Journal of Biochemistry and Cell Biology, vol. 40, pp. 1016 - 1029, http://dx.doi.org/10.1016/j.biocel.2007.11.002

Gelling CL; Dawes IW; Richhardt N; Lill R; Muhlenhoff U, 2008, 'Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes', Molecular and Cellular Biology, vol. 28, pp. 1851 - 1861, http://dx.doi.org/10.1128/MCB.01963-07

Fong C; Temple MD; Alic N; Chiu II; Durchdewald M; Thorpe GW; Higgins VJ; Dawes IW, 2008, 'Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor', FEMS Yeast Research, vol. 8, pp. 386 - 399, http://dx.doi.org/10.1111/j.1567-1364.2007.00349.x

Herst P; Perrone G; Dawes IW; Bircham P; Berridge M, 2008, 'Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits', FEMS Yeast Research, vol. 8, pp. 897 - 905, http://dx.doi.org/10.1111/j.1567-1364.2008.00418.x

Perrone G; Tan S; Dawes IW, 2008, 'Reactive oxygen species and yeast apoptosis', Biochimica et Biophysica ACTA - Molecular Cell Research, vol. 1783, pp. 1354 - 1368, http://dx.doi.org/10.1016/j.bbamcr.2008.01.023

Chiu II; Tillett D; Dawes IW; March PE, 2008, 'Site-directed, Ligase-Independent Mutagenesis (SLIM) for highly efficient mutagenesis of plasmids greater than 8kb', Journal of Microbiological Methods, vol. 73, pp. 195 - 198, http://dx.doi.org/10.1016/j.mimet.2008.02.013

Beckhouse AG; Grant CM; Rogers PJ; Dawes IW; Higgins VJ, 2008, 'The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors', FEMS Yeast Research, vol. 8, pp. 1214 - 1222, http://dx.doi.org/10.1111/j.1567-1364.2008.00439.x


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