Select Publications
Journal articles
1992, 'Subclassification of Class I antiarrhythmic drugs: Enhanced relevance after CAST', Cardiovascular Drugs and Therapy, 6, pp. 519 - 528, http://dx.doi.org/10.1007/BF00055611
,1992, 'Recent developments in the pharmacotherapy of cardiac failure', Medical Journal of Australia, 157, pp. 292 - 294, http://dx.doi.org/10.5694/j.1326-5377.1992.tb137175.x
,1992, 'Treatment of atrial fibrillation: time for change?', Medical Journal of Australia, 157, pp. 78 - 80, http://dx.doi.org/10.5694/j.1326-5377.1992.tb137029.x
,1991, 'DIFFERENTIAL EFFECTS ON ACTION POTENTIAL DURATION OF CLASS IA, B AND C ANTIARRHYTHMIC DRUGS: MODULATION BY STIMULATION RATE AND EXTRACELLULAR K+ CONCENTRATION', Clinical and Experimental Pharmacology and Physiology, 18, pp. 533 - 541, http://dx.doi.org/10.1111/j.1440-1681.1991.tb01488.x
,1991, 'Effects of hyperkalemia, acidosis, and hypoxia on the depression of maximum rate of depolarization by class I antiarrhythmic drugs in guinea pig myocardium: Differential actions of class Ib and Ic agents', Journal of Cardiovascular Pharmacology, 18, pp. 51 - 60, http://dx.doi.org/10.1097/00005344-199107000-00008
,1990, 'Proarrhythmic actions of antiarrhythmic drugs: a review', Australian and New Zealand Journal of Medicine, 20, pp. 275 - 282, http://dx.doi.org/10.1111/j.1445-5994.1990.tb01039.x
,1990, 'SELECTIVE DEPRESSION OF MAXIMUM RATE OF DEPOLARIZATION OF GUINEA‐PIG VENTRICULAR ACTION POTENTIALS BY AMIODARONE AND LIGNOCAINE IN SIMULATED ISCHAEMIA: COMPARISON WITH ENCAINIDE', Clinical and Experimental Pharmacology and Physiology, 17, pp. 135 - 145, http://dx.doi.org/10.1111/j.1440-1681.1990.tb01296.x
,1989, 'Characteristics of cardiac action potentials in marsupials', Journal of Comparative Physiology B, 158, pp. 759 - 762, http://dx.doi.org/10.1007/BF00693014
,1989, 'Cardiac electrophysiological actions of captopril: Lack of direct antiarrhythmic effects', British Journal of Pharmacology, 98, pp. 192 - 196, http://dx.doi.org/10.1111/j.1476-5381.1989.tb16881.x
,1989, 'Depression of maximum rate of depolarization of guinea-pig ventricular action potentials by metabolites of encainide', British Journal of Pharmacology, 97, pp. 619 - 625, http://dx.doi.org/10.1111/j.1476-5381.1989.tb11994.x
,1988, 'SELECTIVE DEPRESSION OF CONDUCTION-VELOCITY OF PREMATURE ACTION-POTENTIALS IN CANINE PURKINJE-FIBERS BY CLASS IB ANTIARRHYTHMIC DRUGS - COMPARISON WITH IA AND IC DRUGS', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 18, pp. 389 - 389, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1988N917000179&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,1988, 'Flecainide compared with a combination of digoxin and disopyramide for acute atrial arrhythmias after cardiopulmonary bypass', Heart, 60, pp. 497 - 501, http://dx.doi.org/10.1136/hrt.60.6.497
,1988, 'Selective depression of conduction of premature action potentials in canine purkinje fibres by class lb antiarrhythmic drugs: Comparison with la and ic drugs', Cardiovascular Research, 22, pp. 171 - 178, http://dx.doi.org/10.1093/cvr/22.3.171
,1987, 'A POSSIBLE ROLE FOR FREE RADICALS IN CARDIAC REPERFUSION PHENOMENA', Australian and New Zealand Journal of Medicine, 17, pp. 459 - 460, http://dx.doi.org/10.1111/j.1445-5994.1987.tb00095.x
,1987, 'Cellular electrophysiological effects of d‐and dl‐sotalol in guinea‐pig sinoatrial node, atrium and ventricle and human atrium: differential tissue sensitivity', British Journal of Pharmacology, 90, pp. 593 - 599, http://dx.doi.org/10.1111/j.1476-5381.1987.tb11210.x
,1987, 'Differing electrophysiological effects of class IA, IB and IC antiarrhythmic drugs on guinea‐pig sinoatrial node', British Journal of Pharmacology, 91, pp. 395 - 401, http://dx.doi.org/10.1111/j.1476-5381.1987.tb10294.x
,1987, 'Long-term survival after counterpulsation for medically refractory heart failure complicating myocardial infarction and cardiac surgery', European Heart Journal, 8, pp. 490 - 502, http://dx.doi.org/10.1093/oxfordjournals.eurheartj.a062309
,1987, 'Proarrhythmic effects of an oxygen-derived free radical generating system on action potentials recorded from guinea pig ventricular myocardium: A possible cause of reperfusion-induced arrhythmias', Circulation Research, 61, pp. 50 - 54, http://dx.doi.org/10.1161/01.RES.61.1.50
,1987, 'Resting, and rate‐dependent depression of of guinea‐pig ventricular action potentials by amiodarone and desethylamiodarone', British Journal of Pharmacology, 92, pp. 97 - 103, http://dx.doi.org/10.1111/j.1476-5381.1987.tb11300.x
,1986, 'THE PREVALENCE OF ARRHYTHMIAS IN HYPERTROPHIC CARDIOMYOPATHY: ROLE OF AMBULATORY MONITORING AND SIGNAL‐AVERAGED ELECTROCARDIOGRAPHY', Australian and New Zealand Journal of Medicine, 16, pp. 666 - 670, http://dx.doi.org/10.1111/j.1445-5994.1986.tb00009.x
,1985, 'Cardiac arrhythmias. Mechanism and management.', Australian family physician, 14, pp. 1228 - 1232
,1985, 'ATRIAL TACHYARRHYTHMIAS AFTER CARDIAC SURGERY: RESULTS OF DISOPYRAMIDE THERAPY', Australian and New Zealand Journal of Medicine, 15, pp. 27 - 32, http://dx.doi.org/10.1111/j.1445-5994.1985.tb02726.x
,1985, 'Intravenous sotalol for the treatment of atrial fibrillation and flutter after cardiopulmonary bypass: Comparison with disopyramide and digoxin in a randomised trial', British Heart Journal, 54, pp. 86 - 90, http://dx.doi.org/10.1136/hrt.54.1.86
,1984, 'Antiarrhythmic agents', Medical Journal of Australia, 141, pp. 718 - 723, http://dx.doi.org/10.5694/j.1326-5377.1984.tb113231.x
,1983, 'Importance of physico-chemical properties in determining the kinetics of the effects of Class I antiarrhythmic drugs on maximum rate of depolarisation in the guinea-pig ventricle.', British Journal of Pharmacology, 80, pp. 33
,1983, 'Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification', Cardiovascular Research, 17, pp. 344 - 352
,1983, 'Resting and rate-dependent depression of maximum rate of depolarisation (Vmax) in guinea-pig ventricular action potentials by mexiletine, disopyramide and encainide', Journal of Cardiovascular Pharmacology, 5, pp. 291 - 296
,1983, 'Voltage-and time -dependent depression of maximum rate of depolarisation of guinea-pig ventricular action potentials of two new anti-arrhythmic drugs, flecainide and lorcainide', Cardiovascular Research, 17, pp. 251 - 258
,1982, 'Electrophysiological and other effects on rabbit hearts of CCI 22277, a new steroidal antiarrhythmic drug', British Journal of Pharmacology, 76, pp. 337 - 344
,1982, 'Electrophysiological effects of labetolol on rabbit atrial, ventricular and Purkinje cells in normoxia and hypoxia', Cardiovascular Research, 16, pp. 233 - 239
,1982, 'The effects of nadolol on various cardiac tissues in normoxia and on atrial muscle in simulated ischaemia', European Journal of Pharmacology, 83, pp. 161 - 169
,1982, 'Voltage-and time-dependent depression of maximum rate of depolarisation of guinea-pig ventricular action potentials by two steroidal anti-arrhythmic drugs, CCI 22277 and Org 6001', British Journal of Pharmacology, 77, pp. 541 - 548
,1981, 'Randomized controlled trial of intraaortic balloon counterpulsation in early myocardial infarction with acute heart failure', The American Journal of Cardiology, 47, pp. 815 - 820, http://dx.doi.org/10.1016/0002-9149(81)90179-X
,1981, 'Randomized controlled trial of intra-aortic balloon counterpulsation in early myocardial infarction with acute heart failure', American Journal of Cadiology, 47, pp. 815 - 820
,1980, 'Treatment of atrial arrhythmias after cardiac surgery with intravenous disopyramide', Australian and New Zealand Journal of Medicine, 10, pp. 394 - 395
,1980, 'Treatment of atrial arrhythmias after cardiac surgery with intravenous disopyramide', Australian and New Zealand Journal of Medicine, 10, pp. 644 - 649
,1979, 'Nifedipine in the treatment of life threatening Prinzmetal angina', Australian and New Zealand Journal of Medicine, 9, pp. 293 - 294
,1976, 'Contact cholangiography', The American Journal of Surgery, 132, pp. 562-564
,1973, 'Intrinsic contractility of lymphatics in sheep and in dogs.', Quarterly Journal of Experimental Physiology, 58, pp. 207 - 217
,Conference Papers
2002, 'NCC27 (CLIC1) interacts with artifical bylayer in a pH dependent manner to form chloride ion channels', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 244A - 244A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000173252701198&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2001, 'Modification of HERG channel properties under conditions of simulated myocardial ischemia', in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, pp. 114A - 115A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166914400526&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,1999, 'Effect of Dofetilide and Sotalol on echocardiographic parameters after cardioversion from atrial fibrillation and flutter', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. I-287 - I-276, presented at 72nd Scientific Session Conference, Atlanta, Georgia USA, 07 November 1999 - 10 November 1999
,1999, 'Oral Dofetilide improves quality of life: An EMERALD substudy', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. I-286 - I286, presented at 72nd Scientific Session Conference, Atlanta, Georgia USA, 07 November 1999 - 10 November 1999
,1999, 'Potential cellular mechanism for the antifibrillatory properties of fish oils: potent blockade of the Kv4.3 current (Ito)', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. I-279 - I-279, presented at 72nd Scientific Session Conference, Atlanta, Georgia USA, 07 November 1999 - 10 November 1999
,1999, 'Modulation of antiarrhythmic actions by myocardial ischaemia', in Proceedings of the Australian Physiological and Pharmacological Society, University of Newcastle, NSW, pp. 125P - 125P, presented at 67th Meeting of Physiology and Pharmacology Society, University of Newcastle, NSW, 27 September 1999 - 29 September 1999
,1999, 'The EMERALD (European and Australian Multicenter Evaluative Research on Atrial Fibrillation Dofetilide) Study Group', in Journal of the American College of Cardiology, Elsevier Science Inc, New York, NY, USA, pp. 132A - 132A, presented at 48th Annual Scientific Session of American College of Cardiology, New Orleans, Louisiana, USA, 07 March 1999 - 10 March 1999
,1999, 'Potential cellular mechanism for the antifibrillatory properties of fish oils: potent blockade of the Kv4.3 encoded transient outward current.', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 575 - 575, presented at European Society of Cardiology, Barcelona, Spain, -
,1999, 'After one year treatment on dofetilide patients with longer post-cardioversion QT (QTc) interval are more likely to remain in sinus rhythm', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 587 - 587, presented at European Society of Cardiology, Barcelona, Spain
,1999, 'Blockade of the human ether-a-go-go-related gene (HERG) potassium channel by amitriptyline: Another mechanism for cardiotoxicity', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 329 - 329, presented at European Society of Cardiology, Barcelona, Spain
,1999, 'Dofetilide improves quality of life', in European Heart Journal, W B Saunders Company Ltd, London, England, pp. 587 - 587, presented at European Society of Cardiology, Barcelona, Spain
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