By Mr Arnold Reynaldi

Journal articles

Cromer D; Reynaldi A; Mitchell A; Schlub TE; Juno JA; Wheatley AK; Kent SJ; Khoury DS; Davenport MP, 2024, 'Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-52194-9

Kent SJ; Li S; Amarasena TH; Reynaldi A; Lee WS; Leeming MG; O’Connor DH; Nguyen J; Kent HE; Caruso F; Juno JA; Wheatley AK; Davenport MP; Ju Y, 2024, 'Blood Distribution of SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine in Humans', ACS Nano, 18, pp. 27077 - 27089, http://dx.doi.org/10.1021/acsnano.4c11652

Lee WS; Audsley J; Trieu MC; Reynaldi A; Aurelia LC; Mehta PH; Patterson J; Kent HE; Nguyen J; Amarasena T; Esterbauer R; Haycroft ER; Ramanathan P; Davenport MP; Schlub TE; Sasadeusz J; Wheatley AK; Chung AW; Juno JA; Selva KJ; Kent SJ, 2024, 'Randomized controlled trial reveals no benefit to a 3-month delay in COVID-19 mRNA booster vaccine', Journal of Clinical Investigation, 134, http://dx.doi.org/10.1172/JCI181244

Underwood AP; Gupta M; Wu BR; Eltahla AA; Boo I; Wang JJ; Agapiou D; Abayasingam A; Reynaldi A; Keoshkerian E; Zhao Y; Brasher N; Walker MR; Bukh J; Maher L; Gordon T; Davenport MP; Luciani F; Drummer HE; Lloyd AR; Bull RA, 2024, 'B-cell characteristics define HCV reinfection outcome', Journal of Hepatology, 81, pp. 415 - 428, http://dx.doi.org/10.1016/j.jhep.2024.04.004

Wagstaffe HR; Thwaites RS; Reynaldi A; Sidhu JK; McKendry R; Ascough S; Papargyris L; Collins AM; Xu J; Lemm NM; Siggins MK; Chain BM; Killingley B; Kalinova M; Mann A; Catchpole A; Davenport MP; Openshaw PJM; Chiu C, 2024, 'Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults', Science Immunology, 9, http://dx.doi.org/10.1126/sciimmunol.adj9285

Cromer D; Steain M; Reynaldi A; Schlub TE; Khan SR; Sasson SC; Kent SJ; Khoury DS; Davenport MP, 2023, 'Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis', Nature Communications, 14, pp. 1633, http://dx.doi.org/10.1038/s41467-023-37176-7

Lee WS; Tan HX; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent HE; Aggarwal A; Turville SG; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson DA; Cromer D; Davenport MP; Kent SJ; Juno JA; Khoury DS; Wheatley AK, 2023, 'Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.adg5301

Koutsakos M; Reynaldi A; Lee WS; Nguyen J; Amarasena T; Taiaroa G; Kinsella P; Liew KC; Tran T; Kent HE; Tan HX; Rowntree LC; Nguyen THO; Thomas PG; Kedzierska K; Petersen J; Rossjohn J; Williamson DA; Khoury D; Davenport MP; Kent SJ; Wheatley AK; Juno JA, 2023, 'SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses', Immunity, 56, pp. 879 - 892.e4, http://dx.doi.org/10.1016/j.immuni.2023.02.017

Habel JR; Chua BY; Kedzierski L; Selva KJ; Damelang T; Haycroft ER; Nguyen THO; Koay HF; Nicholson S; McQuilten HA; Jia X; Allen LF; Hensen L; Zhang W; van de Sandt CE; Neil JA; Pragastis K; Lau JSY; Jumarang J; Allen EK; Amanant F; Krammer F; Wragg KM; Juno JA; Wheatley AK; Tan HX; Pell G; Walker S; Audsley J; Reynaldi A; Thevarajan I; Denholm JT; Subbarao K; Davenport MP; Hogarth PM; Godfrey DI; Cheng AC; Tong SYC; Bond K; Williamson DA; McMahon JH; Thomas PG; Pannaraj PS; James F; Holmes NE; Smibert OC; Trubiano JA; Gordon CL; Chung AW; Whitehead CL; Kent SJ; Lappas M; Rowntree LC; Kedzierska K, 2023, 'Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations', JCI Insight, 8, http://dx.doi.org/10.1172/jci.insight.167157

Selva KJ; Ramanathan P; Haycroft ER; Reynaldi A; Cromer D; Tan CW; Wang LF; Wines BD; Hogarth PM; Downie LE; Davis SK; Purcell RA; Kent HE; Juno JA; Wheatley AK; Davenport MP; Kent SJ; Chung AW, 2023, 'Preexisting immunity restricts mucosal antibody recognition of SARS-CoV-2 and Fc profiles during breakthrough infections', JCI Insight, 8, http://dx.doi.org/10.1172/jci.insight.172470

Underwood AP; Gupta M; Wu B-R; Eltahla AA; Boo I; Wang JJ; Agapiou D; Abayasingam A; Reynaldi A; Keoshkerian E; Zhao Y; Brasher N; Walker MR; Bukh J; Maher L; Gordon T; Davenport M; Luciani F; Drummer HE; Lloyd AR; Bull RA, 2023, 'B Cell Signatures and Antibody Imprinting Define HCV Reinfection Outcome', , http://dx.doi.org/10.2139/ssrn.4418620

Tabilas C; Iu DS; Daly CWP; Yee Mon KJ; Reynaldi A; Wesnak SP; Grenier JK; Davenport MP; Smith NL; Grimson A; Rudd BD, 2022, 'Early microbial exposure shapes adult immunity by altering CD8+ T cell development', Proceedings of the National Academy of Sciences of the United States of America, 119, http://dx.doi.org/10.1073/pnas.2212548119

Koutsakos M; Lee WS; Reynaldi A; Tan HX; Gare G; Kinsella P; Liew KC; Taiaroa G; Williamson DA; Kent HE; Stadler E; Cromer D; Khoury DS; Wheatley AK; Juno JA; Davenport MP; Kent SJ, 2022, 'The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants', Immunity, 55, pp. 1316 - 1326.e4, http://dx.doi.org/10.1016/j.immuni.2022.05.018

Cromer D; Reynaldi A; Steain M; Triccas JA; Davenport MP; Khoury DS, 2022, 'Relating in Vitro Neutralization Level and Protection in the CVnCoV (CUREVAC) Trial', Clinical Infectious Diseases, 75, pp. E878 - E879, http://dx.doi.org/10.1093/cid/ciac075

Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397, http://dx.doi.org/10.1038/s41577-022-00716-1

Goel RR; Painter MM; Lundgreen KA; Apostolidis SA; Baxter AE; Giles JR; Mathew D; Pattekar A; Reynaldi A; Khoury DS; Gouma S; Hicks P; Dysinger S; Hicks A; Sharma H; Herring S; Korte S; KC W; Oldridge DA; Erickson RI; Weirick ME; McAllister CM; Awofolaju M; Tanenbaum N; Dougherty J; Long S; D'Andrea K; Hamilton JT; McLaughlin M; Williams JC; Adamski S; Kuthuru O; Drapeau EM; Davenport MP; Hensley SE; Bates P; Greenplate AR; Wherry EJ, 2022, 'Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine', Cell, 185, pp. 1875 - 1887.e8, http://dx.doi.org/10.1016/j.cell.2022.04.009

Stern J; Solomon A; Dantanarayana A; Pascoe R; Reynaldi A; Davenport MP; Milush J; Deeks SG; Hartogensis W; Hecht FM; Cockerham L; Roche M; Lewin SR, 2022, 'Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy', Journal of Infectious Diseases, 225, pp. 1721 - 1730, http://dx.doi.org/10.1093/infdis/jiab533

Wragg KM; Lee WS; Koutsakos M; Tan HX; Amarasena T; Reynaldi A; Gare G; Konstandopoulos P; Field KR; Esterbauer R; Kent HE; Davenport MP; Wheatley AK; Kent SJ; Juno JA, 2022, 'Establishment and recall of SARS-CoV-2 spike epitope-specific CD4⁺ T cell memory', Nature Immunology, 23, pp. 768 - 780, http://dx.doi.org/10.1038/s41590-022-01175-5

Habel JR; Chua BY; Kedzierski L; Selva KJ; Damelang T; Haycroft ER; Nguyen THO; Koay H-F; Nicholson S; McQuilten H; Jia X; Allen LF; Hensen L; Zhang W; van de Sandt CE; Neil JA; Amanant F; Krammer F; Wragg K; Juno JA; Wheatley AK; Tan H-X; Pell G; Audsley J; Reynaldi A; Thevarajan I; Denholm J; Subbarao K; Davenport MP; Hogarth M; Godrey DI; Cheng AC; Tong SYC; Bond K; Williamson DA; James F; Holmes NE; Smibert OC; Trubiano JA; Gordon CL; Chung AW; Whitehead C; Kent SJ; Lappas M; Rowntree LC; Kedzierska K, 2022, 'Integrated immune networks in SARS-CoV-2 infected pregnant women reveal differential NK cell and unconventional T cell activation', The Journal of Immunology, 208, pp. 125.10 - 125.10, http://dx.doi.org/10.4049/jimmunol.208.supp.125.10

Cromer D; Steain M; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Kent SJ; Triccas JA; Khoury DS; Davenport MP, 2022, 'Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis', The Lancet Microbe, 3, pp. e52 - e61, http://dx.doi.org/10.1016/S2666-5247(21)00267-6

Goel RR; Painter MM; Apostolidis SA; Mathew D; Meng W; Rosenfeld AM; Lundgreen KA; Reynaldi A; Khoury DS; Pattekar A; Gouma S; Kuri-Cervantes L; Hicks P; Dysinger S; Hicks A; Sharma H; Herring S; Korte S; Baxter AE; Oldridge DA; Giles JR; Weirick ME; McAllister CM; Awofolaju M; Tanenbaum N; Drapeau EM; Dougherty J; Long S; D’Andrea K; Hamilton JT; McLaughlin M; Williams JC; Adamski S; Kuthuru O; Frank I; Betts MR; Vella LA; Grifoni A; Weiskopf D; Sette A; Hensley SE; Davenport MP; Bates P; Luning Prak ET; Greenplate AR; John Wherry E, 2021, 'mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern', Science, 374, http://dx.doi.org/10.1126/science.abm0829

Wheatley AK; Juno JA; Wang JJ; Selva KJ; Reynaldi A; Tan HX; Lee WS; Wragg KM; Kelly HG; Esterbauer R; Davis SK; Kent HE; Mordant FL; Schlub TE; Gordon DL; Khoury DS; Subbarao K; Cromer D; Gordon TP; Chung AW; Davenport MP; Kent SJ, 2021, 'Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-21444-5

Lee WS; Reynaldi A; Amarasena T; Davenport MP; Parsons MS; Kent SJ, 2021, 'Anti-Drug Antibodies in Pigtailed Macaques Receiving HIV Broadly Neutralising Antibody PGT121', Frontiers in Immunology, 12, http://dx.doi.org/10.3389/fimmu.2021.749891

Juno J; Wragg K; Lee WS; Amarasena T; Reynaldi A; Koutsakos M; Konstandopoulos P; Field K; Esterbauer R; Tan H-X; Kent H; Davenport M; Wheatley A; Kent S, 2021, 'Tracking the kinetics and phenotype of spike epitope-specific CD4 T cell immunity in the context of SARS-CoV-2 infection and vaccination', , http://dx.doi.org/10.21203/rs.3.rs-957030/v1

Khoury DS; Cromer D; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Subbarao K; Kent SJ; Triccas JA; Davenport MP, 2021, 'Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection', Nature Medicine, 27, pp. 1205 - 1211, http://dx.doi.org/10.1038/s41591-021-01377-8

Lee WS; Selva KJ; Davis SK; Wines BD; Reynaldi A; Esterbauer R; Kelly HG; Haycroft ER; Tan HX; Juno JA; Wheatley AK; Hogarth PM; Cromer D; Davenport MP; Chung AW; Kent SJ, 2021, 'Decay of Fc-dependent antibody functions after mild to moderate COVID-19', Cell Reports Medicine, 2, http://dx.doi.org/10.1016/j.xcrm.2021.100296

Cromer D; Juno JA; Khoury D; Reynaldi A; Wheatley AK; Kent SJ; Davenport MP, 2021, 'Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection', Nature Reviews Immunology, 21, pp. 395 - 404, http://dx.doi.org/10.1038/s41577-021-00550-x

Margaretha H; Reynaldi A; Sofian F; Jap L; Saputra KVI, 2021, 'A Dynamical Model of Dengue Primary and Secondary Infections with an Application to Microinsurance', International Journal of Mathematics and Computer Science, 16, pp. 1045 - 1062

Selva KJ; Davis SK; Haycroft ER; Lee WS; Lopez E; Reynaldi A; Davenport MP; Kent HE; Juno JA; Chung AW; Kent SJ, 2021, 'Tear antibodies to SARS-CoV-2: implications for transmission', Clinical and Translational Immunology, 10, http://dx.doi.org/10.1002/cti2.1354

Cromer D; Reynaldi A; Steain M; Triccas J; Davenport M; Khoury D, 2021, 'Relating in vitro neutralisation level and protection in the CVnCoV (CUREVAC) trial', , http://dx.doi.org/10.1101/2021.06.29.21259504

Cromer D; Steain M; Reynaldi A; Schlub T; Wheatley A; Juno J; Kent S; Triccas J; Khoury D; Davenport M, 2021, 'SARS-CoV-2 variants: levels of neutralisation required for protective immunity', , http://dx.doi.org/10.1101/2021.08.11.21261876

Selva K; Davis S; Haycroft E; Lee WS; Lopez E; Reynaldi A; Davenport M; Kent H; Juno J; Chung A; Kent S, 2021, 'Tear antibodies to SARS-CoV-2: implications for transmission', , http://dx.doi.org/10.1101/2021.08.02.21261479

Khoury D; Cromer D; Reynaldi A; Schlub T; Wheatley A; Juno J; Subbarao K; Kent S; Triccas J; Davenport M, 2021, 'What level of neutralising antibody protects from COVID-19?', , http://dx.doi.org/10.1101/2021.03.09.21252641

Khoury DS; Wheatley AK; Ramuta MD; Reynaldi A; Cromer D; Subbarao K; O’Connor DH; Kent SJ; Davenport MP, 2020, 'Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models', Nature Reviews Immunology, 20, pp. 727 - 738, http://dx.doi.org/10.1038/s41577-020-00471-1

Ju Y; Kelly HG; Dagley LF; Reynaldi A; Schlub TE; Spall SK; Bell CA; Cui J; Mitchell AJ; Lin Z; Wheatley AK; Thurecht KJ; Davenport MP; Webb AI; Caruso F; Kent SJ, 2020, 'Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood', ACS Nano, 14, pp. 15723 - 15737, http://dx.doi.org/10.1021/acsnano.0c06679

Juno JA; Tan HX; Lee WS; Reynaldi A; Kelly HG; Wragg K; Esterbauer R; Kent HE; Batten CJ; Mordant FL; Gherardin NA; Pymm P; Dietrich MH; Scott NE; Tham WH; Godfrey DI; Subbarao K; Davenport MP; Kent SJ; Wheatley AK, 2020, 'Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19', Nature Medicine, 26, pp. 1428 - 1434, http://dx.doi.org/10.1038/s41591-020-0995-0

Vanderven HA; Barr I; Reynaldi A; Wheatley AK; Wines BD; Davenport MP; Hogarth PM; Kent SJ, 2020, 'Fc functional antibody responses to adjuvanted versus unadjuvanted seasonal influenza vaccination in community-dwelling older adults', Vaccine, 38, pp. 2368 - 2377, http://dx.doi.org/10.1016/j.vaccine.2020.01.066

Reynaldi A; Dent AE; Schlub TE; Ogolla S; Rochford R; Davenport MP, 2019, 'Interaction between maternally derived antibodies and heterogeneity in exposure combined to determine time-to-first Plasmodium falciparum infection in Kenyan infants', Malaria Journal, 18, pp. 19, http://dx.doi.org/10.1186/s12936-019-2657-6

Parsons MS; Lee WS; Kristensen AB; Amarasena T; Khoury G; Wheatley AK; Reynaldi A; Wines BD; Hogarth PM; Davenport MP; Kent SJ, 2019, 'Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques', Journal of Clinical Investigation, 129, pp. 182 - 191, http://dx.doi.org/10.1172/JCI122466

Deleage C; Immonen TT; Fennessey CM; Reynaldi A; Reid C; Newman L; Lipkey L; Schlub TE; Camus C; O'Brien S; Smedley J; Conway JM; Del Prete GQ; Davenport MP; Lifson JD; Estes JD; Keele BF, 2019, 'Defining early SIV replication and dissemination dynamics following vaginal transmission', Science Advances, 5, pp. eaav7116, http://dx.doi.org/10.1126/sciadv.aav7116

Reynaldi A; Smith NL; Schlub TE; Tabilas C; Venturi V; Rudd BD; Davenport MP, 2019, 'Fate mapping reveals the age structure of the peripheral T cell compartment', Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 3974 - 3981, http://dx.doi.org/10.1073/pnas.1811634116

Stern J; Roche M; Solomon A; Dantanarayana A; Reynaldi A; Davenport M; Deeks SG; Hartogenesis W; Hecht FM; Cockerham L; Lewin SR, 2019, 'Cell-associated HIV RNA and the ratio of HIV RNA to DNA have circadian cycles in HIV-positive individuals on antiretoviral therapy', Journal of Virus Eradication, 5, pp. 10 - 10, http://dx.doi.org/10.1016/s2055-6640(20)31037-2

Pino M; King C; Shim I; Wang H; Nguyen K; Samer S; Harper J; Lifson J; Reynaldi A; Deleage C; Padhan K; Cervasi B; Davenport MP; Petrovas C; Lederman MM; Paiardini M, 2019, 'Fingolimod treatment at ART initiation delays SIV rebound after ART interruption', Journal of Virus Eradication, 5, pp. 3 - 3, http://dx.doi.org/10.1016/s2055-6640(20)31078-5

Smith NL; Patel RK; Reynaldi A; Grenier JK; Wang J; Watson NB; Nzingha K; Yee Mon KJ; Peng SA; Grimson A; Davenport MP; Rudd BD, 2018, 'Developmental Origin Governs CD8⁺ T Cell Fate Decisions during Infection', Cell, 174, pp. 117 - 130.e14, http://dx.doi.org/10.1016/j.cell.2018.05.029

Lloyd SB; Niven KP; Kiefel BR; Montefiori DC; Reynaldi A; Davenport MP; Kent SJ; Winnall WR, 2017, 'Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV', Human Vaccines and Immunotherapeutics, 13, pp. 2726 - 2737, http://dx.doi.org/10.1080/21645515.2017.1368935

Lee WS; Kristensen AB; Rasmussen TA; Tolstrup M; Østergaard L; Søgaard OS; Wines BD; Mark Hogarth P; Reynaldi A; Davenport MP; Emery S; Amin J; Cooper DA; Kan VL; Fox J; Gruell H; Parsons MS; Kent SJ, 2017, 'Anti-HIV-1 ADCC antibodies following latency reversal and treatment interruption', Journal of Virology, 91, pp. 10.1128/jvi.00603 - 10.1128/jvi.00617, http://dx.doi.org/10.1128/JVI.00603-17

Vanderven HA; Liu L; Ana-Sosa-Batiz F; Nguyen THO; Wan Y; Wines B; Mark Hogarth P; Tilmanis D; Reynaldi A; Parsons MS; Hurt AC; Davenport MP; Kotsimbos T; Cheng AC; Kedzierska K; Zhang X; Xu J; Kent SJ, 2017, 'Fc functional antibodies in humans with severe H7N9 and seasonal influenza', Journal of Clinical Investigation, 2, pp. e92750, http://dx.doi.org/10.1172/jci.insight.92750

Fennessey CM; Pinkevych M; Immonen TT; Reynaldi A; Venturi V; Nadella P; Reid C; Newman L; Lipkey L; Oswald K; Bosche WJ; Trivett MT; Ott DE; Estes JD; Del Prete GQ; Lifson JD; Davenport MP; Keele BF, 2017, 'Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy', PLoS Pathogens, 13, pp. e1006359, http://dx.doi.org/10.1371/journal.ppat.1006359

Lee WS; Kristensen AB; Tolstrup M; Østergaard L; Søgaard OS; Wines BD; Hogarth PM; Reynaldi A; Davenport M; Emery S; Amin J; Cooper DA; Kan V; Fox J; Grüll H; Parsons MS; Kent SJ; Rasmussen TA, 2017, '13 HIV-1-specific ADCC following anti-latency therapy and analytical treatment interruption', Journal of Virus Eradication, 3, pp. 10 - 10, http://dx.doi.org/10.1016/s2055-6640(20)30718-4

Reynaldi A; Schlub TE; Piriou E; Ogolla S; Sumba OP; Moormann AM; Rochford R; Davenport MP, 2016, 'Modeling of EBV Infection and Antibody Responses in Kenyan Infants with Different Levels of Malaria Exposure Shows Maternal Antibody Decay is a Major Determinant of Early EBV Infection', Journal of Infectious Diseases, 214, pp. 1390 - 1398, http://dx.doi.org/10.1093/infdis/jiw396

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