By Professor Bruce Neal

Journal articles

Oshima M; Jardine MJ; Agarwal R; Bakris G; Cannon CP; Charytan DM; de Zeeuw D; Edwards R; Greene T; Levin A; Lim SK; Mahaffey KW; Neal B; Pollock C; Rosenthal N; Wheeler DC; Zhang H; Zinman B; Perkovic V; Heerspink HJL, 2021, 'Insights from CREDENCE trial indicate an acute drop in estimated glomerular filtration rate during treatment with canagliflozin with implications for clinical practice', Kidney International, 99, pp. 999 - 1009, http://dx.doi.org/10.1016/j.kint.2020.10.042

Lam D; Nadkarni G; Neal B; Mahaffey K; Rosenthal N; Hansen M; COCA S; Heerspink H, 2021, 'POS-223 Clinical Utility of KidneyIntelX in Patients with Early Stages of Diabetic Kidney Disease in CANVAS Participants', Kidney International Reports, 6, pp. s93 - s94, http://dx.doi.org/10.1016/j.ekir.2021.03.237

Sarraju A; Li JW; Cannon CP; Chang TI; Agarwal R; Bakris G; Charytan DM; de Zeeuw D; Greene T; Heerspink HJL; Levin A; Neal B; Pollock C; Wheeler DC; Yavin Y; Zhang H; Zinman B; Perkovic V; Jardine M; Mahaffey KW, 2021, 'Effects of canagliflozin on cardiovascular, renal, and safety outcomes in participants with type 2 diabetes and chronic kidney disease according to history of heart failure: Results from the CREDENCE trial', American Heart Journal, 233, pp. 141 - 148, http://dx.doi.org/10.1016/j.ahj.2020.12.008

Yu J; Zhou Z; Mahaffey KW; Matthews DR; Neuen BL; Heerspink HJL; Jardine MJ; Li JW; Perkovic V; Neal B; Arnott C, 2021, 'An exploration of the heterogeneity in effects of SGLT2 inhibition on cardiovascular and all-cause mortality in the EMPA-REG OUTCOME, CANVAS Program, DECLARE-TIMI 58, and CREDENCE trials', International Journal of Cardiology, 324, pp. 165 - 172, http://dx.doi.org/10.1016/j.ijcard.2020.09.050

Yin X; Tian M; Neal B, 2021, 'Sodium Reduction: How Big Might the Risks and Benefits Be?', Heart Lung and Circulation, 30, pp. 180 - 185, http://dx.doi.org/10.1016/j.hlc.2020.07.011

Neuen BL; Arnott C; Perkovic V; Figtree G; de Zeeuw D; Fulcher G; Jun M; Jardine MJ; Zoungas S; Pollock C; Mahaffey KW; Neal B; Heerspink HJL, 2021, 'Sodium-glucose co-transporter-2 inhibitors with and without metformin: A meta-analysis of cardiovascular, kidney and mortality outcomes', Diabetes, Obesity and Metabolism, 23, pp. 382 - 390, http://dx.doi.org/10.1111/dom.14226

Dunford EK; Farrand C; Huffman MD; Raj TS; Shahid M; Ni Mhurchu C; Neal B; Johnson C, 2021, 'Availability, healthiness, and price of packaged and unpackaged foods in India: A cross-sectional study', Nutrition and Health, 28, pp. 571 - 579, http://dx.doi.org/10.1177/02601060211039124

Januzzi JL; Butler J; Sattar N; Xu J; Shaw W; Rosenthal N; Pfeifer M; Mahaffey KW; Neal B; Hansen MK, 2021, 'Insulin-Like Growth Factor Binding Protein 7 Predicts Renal and Cardiovascular Outcomes in the Canagliflozin Cardiovascular Assessment Study', Diabetes Care, 44, pp. 210 - 216, http://dx.doi.org/10.2337/dc20-1889

Jardine M; Zhou Z; Lambers Heerspink HJ; Hockham C; Li Q; Agarwal R; Bakris GL; Cannon CP; Charytan DM; Greene T; Levin A; Li JW; Neuen BL; Neal B; Oh R; Oshima M; Pollock C; Wheeler DC; de Zeeuw D; Zhang H; Zinman B; Mahaffey KW; Perkovic V, 2021, 'Kidney, cardiovascular, and safety outcomes of canagliflozin according to baseline albuminuria a credence secondary analysis', Clinical Journal of the American Society of Nephrology, 16, pp. 384 - 395, http://dx.doi.org/10.2215/CJN.15260920

Neuen BL; Ohkuma T; Neal B; Matthews DR; de Zeeuw D; Mahaffey KW; Fulcher G; Blais J; Li Q; Jardine MJ; Perkovic V; Wheeler DC, 2021, 'Relative and Absolute Risk Reductions in Cardiovascular and Kidney Outcomes With Canagliflozin Across KDIGO Risk Categories: Findings From the CANVAS Program', American Journal of Kidney Diseases, 77, pp. 23 - 34.e1, http://dx.doi.org/10.1053/j.ajkd.2020.06.018

Li C; Zhou Z; Neuen BL; Yu J; Huang Y; Young T; Li J; Li L; Perkovic V; Jardine MJ; Keay L; Markoulli M; Rosenthal N; Capuano G; Yavin Y; Neal B; Arnott C, 2021, 'Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis', Diabetes, Obesity and Metabolism, 23, pp. 252 - 257, http://dx.doi.org/10.1111/dom.14197

Chow CK; Atkins ER; Billot L; Chalmers J; Hillis GS; Hay P; Neal B; Nelson M; Patel A; Reid CM; Schlaich M; Usherwood T; Webster R; Rodgers A, 2021, 'Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol', American Heart Journal, 231, pp. 56 - 67, http://dx.doi.org/10.1016/j.ahj.2020.09.017

Li JW; Guo YT; Di Tanna GL; Neal B; Chen YD; Schutte AE, 2021, 'Vital signs during the COVID-19 outbreak: A retrospective analysis of 19,960 participants in Wuhan and four nearby capital cities in China', Global Heart, 16, pp. 47, http://dx.doi.org/10.5334/GH.913

Yin X; Liu H; Webster J; Trieu K; Huffman MD; Miranda JJ; Marklund M; Wu JHY; Cobb LK; Li KC; Pearson S-A; Neal B; Tian M, 2021, 'Availability, Formulation, Labeling, and Price of Low-sodium Salt Worldwide: Environmental Scan (Preprint)', JMIR Public Health and Surveillance, 7, http://dx.doi.org/10.2196/27423

Yu J; Barraclough J; Neal B; Figtree G; Arnott C, 2021, 'Canagliflozin and Cardiovascular Outcomes in Patients With and Without Peripheral Artery Disease At Baseline: Data from the CANVAS Program and CREDENCE Trials', Heart Lung and Circulation, 30, pp. s215, http://dx.doi.org/10.1016/j.hlc.2021.06.263

Darshi M; Tefera E; Gao B; Weidner-Wells M; Reilly DF; Coorey C; Tang O; Yang J; Neal B; Arnott CG; Mahaffey KW; Perkovic V; Hansen MK; Ferrannini E; Figtree G, 2021, 'Circulating Metabolites to Predict Renal Outcomes in CANVAS Type 2 Diabetes Mellitus Population', Journal of the American Society of Nephrology, 32, pp. 47 - 47, http://dx.doi.org/10.1681/asn.20213210s147a

Yu J; Arnott C; Neuen BL; Heersprink HL; Mahaffey KW; Cannon CP; Khan SS; Baldridge AS; Shah SJ; Huang Y; Li C; Figtree GA; Perkovic V; Jardine MJ; Neal B; Huffman MD, 2021, 'Corrigendum', ESC Heart Failure, 8, pp. 3447 - 3447, http://dx.doi.org/10.1002/ehf2.13408

Coyle D; Shahid M; Dunford E; Ni Mhurchu C; Mckee S; Santos M; Popkin B; Trieu K; Marklund M; Neal B; Wu J, 2021, 'Estimating the potential impact of Australia’s reformulation programme on households’ sodium purchases', BMJ Nutrition, Prevention & Health, 4, pp. 49 - 58, http://dx.doi.org/10.1136/bmjnph-2020-000173

Vasquez-Rios G; Nadkarni GN; Neal B; Mahaffey KW; Hansen MK; Fleming F; Heerspink HJL; Coca SG, 2021, 'KidneyIntelX as an Enrichment Tool for Clinical Trials in Early Diabetic Kidney Disease', Journal of the American Society of Nephrology, 32, pp. 263 - 263, http://dx.doi.org/10.1681/asn.20213210s1263a

Roth GA; Mensah GA; Johnson CO; Addolorato G; Ammirati E; Baddour LM; Barengo NC; Beaton A; Benjamin EJ; Benziger CP; Bonny A; Brauer M; Brodmann M; Cahill TJ; Carapetis JR; Catapano AL; Chugh S; Cooper LT; Coresh J; Criqui MH; DeCleene NK; Eagle KA; Emmons-Bell S; Feigin VL; Fernández-Sola J; Fowkes FGR; Gakidou E; Grundy SM; He FJ; Howard G; Hu F; Inker L; Karthikeyan G; Kassebaum NJ; Koroshetz WJ; Lavie C; Lloyd-Jones D; Lu HS; Mirijello A; Misganaw AT; Mokdad AH; Moran AE; Muntner P; Narula J; Neal B; Ntsekhe M; Oliveira GMM; Otto CM; Owolabi MO; Pratt M; Rajagopalan S; Reitsma MB; Ribeiro ALP; Rigotti NA; Rodgers A; Sable CA; Shakil SS; Sliwa K; Stark BA; Sundström J; Timpel P; Tleyjeh II; Valgimigli M; Vos T; Whelton PK; Yacoub M; Zuhlke LJ; Abbasi-Kangevari M; Abdi A; Abedi A; Aboyans V; Abrha WA; Abu-Gharbieh E; Abushouk AI; Acharya D; Adair T; Adebayo OM; Ademi Z; Advani SM; Afshari K; Afshin A; Agarwal G; Agasthi P; Ahmad S; Ahmadi S; Ahmed MB; Aji B; Akalu Y; Akande-Sholabi W; Aklilu A; Akunna CJ; Alahdab F; Al-Eyadhy A; Alhabib KF; Alif SM; Alipour V; Aljunid SM; Alla F; Almasi-Hashiani A; Almustanyir S; Shawon MSR; Schutte A; Iqbal U; Bhaskar S, 2020, 'Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study', Journal of the American College of Cardiology, 76, pp. 2982 - 3021, http://dx.doi.org/10.1016/j.jacc.2020.11.010

Bakris G; Oshima M; Mahaffey KW; Agarwal R; Cannon CP; Capuano G; Charytan DM; de Zeeuw D; Edwards R; Greene T; Heerspink HJL; Levin A; Neal B; Oh R; Pollock C; Rosenthal N; Wheeler DC; Zhang H; Zinman B; Jardine MJ; Perkovic V, 2020, 'Effects of canagliflozin in patients with baseline eGFR <30 ml/min per 1.73 m²: Subgroup analysis of the randomized CREDENCE trial', Clinical Journal of the American Society of Nephrology, 15, pp. 1705 - 1714, http://dx.doi.org/10.2215/CJN.10140620

Coyle DH; Shahid M; Dunford EK; Mhurchu CN; Mckee S; Santos M; Popkin BM; Trieu K; Marklund M; Taylor F; Neal B; Wu JHY, 2020, 'Correction to: Contribution of major food companies and their products to household dietary sodium purchases in Australia (International Journal of Behavioral Nutrition and Physical Activity, (2020), 17, 1, (81), 10.1186/s12966-020-00982-z)', International Journal of Behavioral Nutrition and Physical Activity, 17, pp. 159, http://dx.doi.org/10.1186/s12966-020-01064-w

Bablani L; Mhurchu CN; Neal B; Skeels CL; Staub KE; Blakely T, 2020, 'The impact of voluntary front-of-pack nutrition labelling on packaged food reformulation: A difference-in-differences analysis of the Australasian Health Star Rating scheme', PLoS Medicine, 17, pp. e1003427, http://dx.doi.org/10.1371/journal.pmed.1003427

Januzzi JL; Xu J; Li JW; Shaw W; Oh R; Pfeifer M; Butler J; Sattar N; Mahaffey KW; Neal B; Hansen MK, 2020, 'Effects of Canagliflozin on Amino-Terminal Pro–B-Type Natriuretic Peptide: Implications for Cardiovascular Risk Reduction', Journal of the American College of Cardiology, 76, pp. 2076 - 2085, http://dx.doi.org/10.1016/j.jacc.2020.09.004

Oshima M; Neuen BL; Jardine MJ; Bakris G; Edwards R; Levin A; Mahaffey KW; Neal B; Pollock C; Rosenthal N; Wada T; Wheeler DC; Perkovic V; Heerspink HJL, 2020, 'Effects of canagliflozin on anaemia in patients with type 2 diabetes and chronic kidney disease: a post-hoc analysis from the CREDENCE trial', The Lancet Diabetes and Endocrinology, 8, pp. 903 - 914, http://dx.doi.org/10.1016/s2213-8587(20)30300-4

Matthews DR; Wysham C; Davies M; Slee A; Alba M; Lee M; Perkovic V; Mahaffey KW; Neal B, 2020, 'Effects of canagliflozin on initiation of insulin and other antihyperglycaemic agents in the CANVAS Program', Diabetes, Obesity and Metabolism, 22, pp. 2199 - 2203, http://dx.doi.org/10.1111/dom.14143

Pan XF; Magliano DJ; Zheng M; Shahid M; Taylor F; Julia C; Mhurchu CN; Pan A; Shaw JE; Neal B; Wu JH, 2020, 'Seventeen-year associations between diet quality defined by the health star rating and mortality in australians: The australian diabetes, obesity and lifestyle study (ausdiab)', Current Developments in Nutrition, 4, pp. nzaa157 - nzaa157, http://dx.doi.org/10.1093/cdn/nzaa157

Arnott C; Neuen BL; Heerspink HJL; Figtree GA; Kosiborod M; Lam CS; Cannon CP; Rosenthal N; Shaw W; Mahaffey KW; Jardine MJ; Perkovic V; Neal B, 2020, 'The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program', International Journal of Cardiology, 318, pp. 126 - 129, http://dx.doi.org/10.1016/j.ijcard.2020.06.011

Oshima M; Neal B; Toyama T; Ohkuma T; Li Q; de Zeeuw D; Heerspink HJL; Mahaffey KW; Fulcher G; Canovatchel W; Matthews DR; Perkovic V, 2020, 'Different eGFR decline thresholds and renal effects of canagliflozin: Data from the CANVAS program', Journal of the American Society of Nephrology, 31, pp. 2446 - 2456, http://dx.doi.org/10.1681/ASN.2019121312

Elliott P; Muller DC; Schneider-Luftman D; Pazoki R; Evangelou E; Dehghan A; Neal B; Tzoulaki I, 2020, 'Estimated 24-Hour Urinary Sodium Excretion and Incident Cardiovascular Disease and Mortality among 398628 Individuals in UK Biobank', Hypertension, 76, pp. 683 - 691, http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14302

Li JW; Neal B; Perkovic V; de Zeeuw D; Neuen BL; Arnott C; Simpson R; Oh R; Mahaffey KW; Heerspink HJL, 2020, 'Mediators of the effects of canagliflozin on kidney protection in patients with type 2 diabetes', Kidney International, 98, pp. 769 - 777, http://dx.doi.org/10.1016/j.kint.2020.04.051

Egnell M; Neal B; Ni Mhurchu C; Rayner M; Jones A; Seconda L; Touvier M; Kesse-Guyot E; Hercberg S; Julia C, 2020, 'Prospective associations of four nutrient profiles with weigh gain, overweight and obesity risk', European Journal of Public Health, 30, pp. ckaa166.1285 - V1009, http://dx.doi.org/10.1093/eurpub/ckaa166.1285

Jin A; Liu K; Labarthe DR; Feng X; Zhang R; Wang H; Qiao Q; Li H; Li J; Gao P; Fang H; Duan P; Wang Y; Zhang H; Cao L; Neal B; Chen J; Wu Y, 2020, 'Impact of salt substitute and stepwise reduction of salt supply on blood pressure in residents in senior residential facilities: Design and rationale of the DECIDE-Salt trial', American Heart Journal, 226, pp. 198 - 205, http://dx.doi.org/10.1016/j.ahj.2020.05.013

Thout SR; Yu J; Tian M; Huffman MD; Arnott C; Li Q; Devarsetty P; Johnson C; Pettigrew S; Neal B; Wu JHY, 2020, 'Rationale, design, and baseline characteristics of the Salt Substitute in India Study (SSiIS): The protocol for a double-blinded, randomized-controlled trial', Journal of Clinical Hypertension, 22, pp. 1504 - 1512, http://dx.doi.org/10.1111/jch.13947

Li JW; Han TW; Woodward M; Anderson CS; Zhou H; Chen YD; Neal B, 2020, 'The impact of 2019 novel coronavirus on heart injury: A Systematic review and Meta-analysis', Progress in Cardiovascular Diseases, 63, pp. 518 - 524, http://dx.doi.org/10.1016/j.pcad.2020.04.008

Badve SV; Pascoe EM; Tiku A; Boudville N; Brown FG; Cass A; Clarke P; Dalbeth N; Day RO; De Zoysa JR; Douglas B; Faull R; Harris DC; Hawley CM; Jones GRD; Kanellis J; Palmer SC; Perkovic V; Rangan GK; Reidlinger D; Robison L; Walker RJ; Walters G; Johnson DW; Neal B, 2020, 'Effects of allopurinol on the progression of chronic kidney disease', New England Journal of Medicine, 382, pp. 2504 - 2513, http://dx.doi.org/10.1056/NEJMoa1915833

Coyle DH; Shahid M; Dunford EK; Mhurchu CN; McKee S; Santos M; Popkin BM; Trieu K; Marklund M; Taylor F; Neal B; Wu JHY, 2020, 'Contribution of major food companies and their products to household dietary sodium purchases in Australia', International Journal of Behavioral Nutrition and Physical Activity, 17, pp. 81, http://dx.doi.org/10.1186/s12966-020-00982-z

LI J; JARDINE MJ; NEAL B; HEERSPINK HL; CANNON C; AGARWAL R; BAKRIS G; CHARYTAN DM; ZEEUW DD; EDWARDS R; GREENE TOM; LEVIN A; POLLOCK CA; ROSENTHAL N; WHEELER DC; ZHANG H; ZINMAN B; PERKOVIC V; MAHAFFEY KW; ARNOTT C, 2020, '27-OR: Effect of Canagliflozin on Total Hospitalization for Heart Failure Events in Patients with Type 2 Diabetes and Chronic Kidney Disease', Diabetes, 69, http://dx.doi.org/10.2337/db20-27-or

Neal B; Marklund M, 2020, 'Is salt substitution ready for prime time?', Nature Reviews Cardiology, 17, pp. 325 - 326, http://dx.doi.org/10.1038/s41569-020-0365-0

Kang A; Neuen B; Heerspink HL; Di Tanna GL; Neal B; Zhang H; Hockham C; Agarwal R; Bakris G; Charytan DM; De Zeeuw D; Greene T; Levin A; Pollock C; Wheeler D; Zinman B; Mahaffey KW; Perkovic V; Jardine M; Lambers Heerspink H, 2020, 'P1013CANAGLIFLOZIN AND RISK OF GENITAL INFECTIONS AND URINARY TRACT INFECTIONS IN PEOPLE WITH DIABETES MELLITUS AND KIDNEY DISEASE- A POST-HOC ANALYSIS OF THE CREDENCE TRIAL', Nephrology Dialysis Transplantation, 35, pp. gfaa142.p1013, http://dx.doi.org/10.1093/ndt/gfaa142.p1013

Kang A; Smyth B; Neuen B; Lambers Heerspink H; Di Tanna GL; Neal B; Zhang H; Hockham C; Agarwal R; Bakris G; Charytan DM; De Zeeuw D; Greene T; Levin A; Pollock C; Wheeler D; Zinman B; Mahaffey KW; Perkovic V; Jardine M, 2020, 'P1019CANAGLIFLOZIN AND RISK OF SKIN AND SOFT TISSUE INFECTIONS IN PEOPLE WITH DIABETES MELLITUS AND KIDNEY DISEASE - A POST-HOC ANALYSIS OF THE CREDENCE TRIAL', Nephrology Dialysis Transplantation, 35, http://dx.doi.org/10.1093/ndt/gfaa142.p1019

Coyle DH; Wu JHY; Di Tanna GL; Shahid M; Taylor F; Neal B; Trevena H, 2020, 'The effects of a supermarket-based intervention on the nutritional quality of private-label foods: A prospective study', Nutrients, 12, pp. 1 - 16, http://dx.doi.org/10.3390/nu12061692

Shahid M; Neal B; Jones A, 2020, 'Uptake of australia’s health star rating system 2014–2019', Nutrients, 12, pp. 1 - 13, http://dx.doi.org/10.3390/nu12061791

Arnott C; Huang Y; Neuen BL; Di Tanna GL; Cannon CP; Oh R; Edwards R; Kavalam M; Rosenthal N; Perkovic V; Jardine MJ; Mahaffey K; Neal B, 2020, 'The effect of canagliflozin on amputation risk in the CANVAS program and the CREDENCE trial.', Diabetes Obes Metab, 22, pp. 1753 - 1766, http://dx.doi.org/10.1111/dom.14091

Bhat S; Marklund M; Henry ME; Appel LJ; Croft KD; Neal B; Wu JHY, 2020, 'A Systematic Review of the Sources of Dietary Salt Around the World', Advances in Nutrition, 11, pp. 677 - 686, http://dx.doi.org/10.1093/advances/nmz134

Jardine MJ; Zhou Z; Mahaffey KW; Oshima M; Agarwal R; Bakris G; Bajaj HS; Bull S; Cannon CP; Charytan DM; De Zeeuw D; Di Tanna GL; Greene T; Heerspink HJL; Levin A; Neal B; Pollock C; Qiu R; Sun T; Wheeler DC; Zhang H; Zinman B; Rosenthal N; Perkovic V, 2020, 'Renal, cardiovascular, and safety outcomes of canagliflozin by baseline kidney function: A secondary analysis of the CREDENCE randomized trial', Journal of the American Society of Nephrology, 31, pp. 1128 - 1139, http://dx.doi.org/10.1681/ASN.2019111168

Heerspink HJL; Li JW; Neal B; de Zeeuw D, 2020, 'Reply: Mediators of the Effects of Canagliflozin on Heart Failure: Central Role of the Cardiorenal Axis', JACC: Heart Failure, 8, pp. 427, http://dx.doi.org/10.1016/j.jchf.2020.02.005

Grimes CA; Khokhar D; Bolton KA; Trieu K; Potter J; Davidson C; Dunford EK; Jan S; Woodward M; Bolam B; Neal B; Nowson C; Webster J, 2020, 'Salt-related knowledge, attitudes and behaviors (KABS) among victorian adults following 22-months of a consumer awareness campaign', Nutrients, 12, pp. 1216, http://dx.doi.org/10.3390/nu12051216

Clemens KK; Woodward M; Neal B; Zinman B, 2020, 'Sex disparities in cardiovascular outcome trials of populations with diabetes: A Systematic Review and Meta-analysis', Diabetes Care, 43, pp. 1157 - 1163, http://dx.doi.org/10.2337/dc19-2257

Marklund M; Singh G; Greer R; Cudhea F; Matsushita K; Micha R; Brady T; Zhao D; Huang L; Tian M; Cobb L; Neal B; Appel LJ; Mozaffarian D; Wu JHY, 2020, 'Estimated population wide benefits and risks in China of lowering sodium through potassium enriched salt substitution: Modelling study', The BMJ, 369, pp. m824, http://dx.doi.org/10.1136/bmj.m824

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