By Professor David Simar

Journal articles

Batten K; Van Doorn N; McManus C; Jones B; Simar D; Broderick C; Bhattacharya K, 2026, 'An exercise intervention in children and young adults with McArdle disease: feasibility, acceptability, and clinical outcomes', Orphanet Journal of Rare Diseases, 21, http://dx.doi.org/10.1186/s13023-026-04222-8

Alqahtani QM; Mizrahi D; Ha L; Fardell JE; Wakefield CE; Simar D; Cohn RJ; Bray P; Docking K; Dylke E, 2026, 'Self-reported physical fitness domains and perceptions of exercise and fatigue among childhood cancer survivors', Jsams Plus, 7, http://dx.doi.org/10.1016/j.jsampl.2026.100140

Ha L; Singleton D; Wakefield CE; Cohn RJ; Simar D; Signorelli C, 2026, 'Structured and Unstructured Physical Activity, Screen Time and Quality of Life in Childhood Cancer Survivors', Cancers, 18, http://dx.doi.org/10.3390/cancers18050752

Macdonald ER; Rose G; Simar D; McCarthy AL; Ford C; Warton K; Hayes S; Clifford BK, 2026, 'Evaluating the utility of circulating cell-free DNA in the context of endometrial cancer: a systematic scoping review', International Journal of Gynecological Cancer, 36, pp. 104767, http://dx.doi.org/10.1016/j.ijgc.2026.104767

Desai I; Pandit A; Smith-Ryan AE; Simar D; Candow DG; Kaakoush NO; Hagstrom AD, 2025, 'The Effect of Creatine Supplementation on Lean Body Mass with and Without Resistance Training', Nutrients, 17, http://dx.doi.org/10.3390/nu17061081

Macdonald ER; Signorelli C; Clifford BK; Simar D; Ward RE, 2024, 'Ballet after breast cancer: A qualitative evaluation of a novel 16-week ballet intervention for women after breast cancer', Jsams Plus, 4, http://dx.doi.org/10.1016/j.jsampl.2024.100076

Macdonald ER; Amorim NML; Hagstrom AD; Markovic K; Simar D; Ward RE; Clifford BK, 2024, 'Evaluating the effect of upper-body morbidity on quality of life following primary breast cancer treatment: a systematic review and meta-analysis', Journal of Cancer Survivorship, 18, pp. 1517 - 1547, http://dx.doi.org/10.1007/s11764-023-01395-0

Desai I; Wewege MA; Jones MD; Clifford BK; Pandit A; Kaakoush NO; Simar D; Hagstrom AD, 2024, 'The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-analysis', Journal of Strength and Conditioning Research, http://dx.doi.org/10.1519/JSC.0000000000004862

Ha L; Wakefield CE; Diaz C; Mizrahi D; Signorelli C; Yacef K; Simar D, 2023, 'Patterns of physical activity and sedentary behavior in child and adolescent cancer survivors assessed using wrist accelerometry: A cluster analysis approach', Health Informatics Journal, 29, http://dx.doi.org/10.1177/14604582231212525

Clifford BK; Amorim NML; Kaakoush NO; Boysen L; Tedla N; Goldstein D; Hardeman EC; Simar D, 2023, 'Irradiation-Induced Dysbiosis: The Compounding Effect of High-Fat Diet on Metabolic and Immune Functions in Mice.', Int J Mol Sci, 24, http://dx.doi.org/10.3390/ijms24065631

Batten K; Bhattacharya K; Simar D; Broderick C, 2023, 'Exercise testing and prescription in patients with inborn errors of muscle energy metabolism.', J Inherit Metab Dis, 46, pp. 763 - 777, http://dx.doi.org/10.1002/jimd.12644

Clifford BK; Kaakoush NO; Tedla N; Goldstein D; Simar D, 2023, 'The effect of exercise intensity on the inflammatory profile of cancer survivors: A randomised crossover study.', Eur J Clin Invest, 53, pp. e13984, http://dx.doi.org/10.1111/eci.13984

Ha L; Wakefield CE; Mizrahi D; Diaz C; Cohn RJ; Signorelli C; Yacef K; Simar D, 2022, 'A Digital Educational Intervention With Wearable Activity Trackers to Support Health Behaviors Among Childhood Cancer Survivors: Pilot Feasibility and Acceptability Study.', JMIR Cancer, 8, pp. e38367, http://dx.doi.org/10.2196/38367

Zhao RR; Mavros Y; Meiklejohn J; Anderberg KA; Singh N; Kay S; Baker MK; Wang Y; Climstein M; O'Sullivan A; De Vos N; Baune BT; Blair SN; Simar D; Fiatarone Singh MA, 2022, 'Effect of High-Intensity Power Training on Cognitive Function in Older Adults With Type 2 Diabetes: Secondary Outcomes of the GREAT2DO Study', JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, http://dx.doi.org/10.1093/gerona/glac090

Macdonald ER; Clifford BK; Simar D; Ward RE, 2022, 'Ballet after breast cancer: investigating the feasibility and acceptability of a novel 16-week classical ballet intervention for breast cancer survivors.', Support Care Cancer, 30, pp. 9909 - 9919, http://dx.doi.org/10.1007/s00520-022-07420-9

Ha L; Wakefield CE; Fardell J; Cohn RJ; Simar D; Signorelli C; Mizrahi D, 2022, 'Parent perceptions of their child's and their own physical activity after treatment for childhood cancer.', Support Care Cancer, 30, pp. 8947 - 8957, http://dx.doi.org/10.1007/s00520-022-07288-9

Clifford BK; Jones MD; Simar D; Barry BK; Goldstein D, 2021, 'The effect of exercise intensity on exercise-induced hypoalgesia in cancer survivors: A randomized crossover trial', Physiological Reports, 9, pp. e15047, http://dx.doi.org/10.14814/phy2.15047

Mosalman Haghighi M; Mavros Y; Kay S; Simpson KA; Baker MK; Wang Y; Zhao RR; Meiklejohn J; Climstein M; O'Sullivan AJ; De Vos N; Baune BT; Blair SN; Simar D; Singh N; Schlicht J; Fiatarone Singh MA, 2021, 'The Effect of High-Intensity Power Training on Habitual, Intervention and Total Physical Activity Levels in Older Adults with Type 2 Diabetes: Secondary Outcomes of the GREAT2DO Randomized Controlled Trial.', Geriatrics (Basel), 6, http://dx.doi.org/10.3390/geriatrics6010015

Ha L; Mizrahi D; Cohn RJ; Simar D; Wakefield CE; Signorelli C, 2021, 'Accuracy of perceived physical activity and fitness levels among childhood cancer survivors.', Pediatr Blood Cancer, 68, pp. e29134, http://dx.doi.org/10.1002/pbc.29134

Tapio S; Little MP; Kaiser JC; Impens N; Hamada N; Georgakilas AG; Simar D; Salomaa S, 2021, 'Ionizing radiation-induced circulatory and metabolic diseases.', Environ Int, 146, pp. 106235, http://dx.doi.org/10.1016/j.envint.2020.106235

Ha L; Mizrahi D; Wakefield CE; Cohn RJ; Simar D; Signorelli C, 2021, 'The Use of Activity Trackers in Interventions for Childhood Cancer Patients and Survivors: A Systematic Review.', J Adolesc Young Adult Oncol, 10, pp. 1 - 14, http://dx.doi.org/10.1089/jayao.2020.0099

Mizrahi D; Fardell JE; Cohn RJ; Partin RE; Howell CR; Hudson MM; Robison LL; Ness KK; McBride J; Field P; Wakefield CE; Simar D, 2020, 'The 6-minute walk test is a good predictor of cardiorespiratory fitness in childhood cancer survivors when access to comprehensive testing is limited.', Int J Cancer, 147, pp. 847 - 855, http://dx.doi.org/10.1002/ijc.32819

Mizrahi D; Wakefield CE; Simar D; Ha L; McBride J; Field P; Cohn RJ; Fardell JE, 2020, 'Barriers and enablers to physical activity and aerobic fitness deficits among childhood cancer survivors.', Pediatr Blood Cancer, 67, pp. e28339, http://dx.doi.org/10.1002/pbc.28339

Bellamy J; Broderick C; Hardy LL; Simar D; Puusepp-Benazzouz H; Ong N; Silove N, 2020, 'Feasibility of a school-based exercise intervention for children with intellectual disability to reduce cardio-metabolic risk.', J Intellect Disabil Res, 64, pp. 7 - 17, http://dx.doi.org/10.1111/jir.12690

Amorim NML; Kee A; Coster ACF; Lucas C; Bould S; Daniel S; Weir JM; Mellett NA; Barbour J; Meikle PJ; Cohn RJ; Turner N; Hardeman EC; Simar D, 2020, 'Irradiation impairs mitochondrial function and skeletal muscle oxidative capacity: significance for metabolic complications in cancer survivors.', Metabolism, 103, pp. 154025, http://dx.doi.org/10.1016/j.metabol.2019.154025

Hiam D; Simar D; Laker R; Altıntaş A; Gibson-Helm M; Fletcher E; Moreno-Asso A; Trewin AJ; Barres R; Stepto NK, 2019, 'Epigenetic Reprogramming of Immune Cells in Women With PCOS Impact Genes Controlling Reproductive Function.', J Clin Endocrinol Metab, 104, pp. 6155 - 6170, http://dx.doi.org/10.1210/jc.2019-01015

Mizrahi D; Wakefield CE; Ha LJ; Cohn R; Simar DE; Fardell J, 2019, 'Satisfaction with an exercise physiology consultation after treatment for childhood cancer: An opportunity for healthy lifestyle education', Heart and Mind, 3, pp. 77 - 106, http://dx.doi.org/10.4103/hm.hm_47_19

Hiam D; Patten R; Gibson-Helm M; Moreno-Asso A; McIlvenna L; Levinger I; Harrison C; Moran LJ; Joham A; Parker A; Shorakae S; Simar D; Stepto N, 2019, 'The effectiveness of high intensity intermittent training on metabolic, reproductive and mental health in women with polycystic ovary syndrome: study protocol for the iHIT- randomised controlled trial.', Trials, 20, pp. 221, http://dx.doi.org/10.1186/s13063-019-3313-8

Poupeau A; Garde C; Sulek K; Citirikkaya K; Treebak JT; Arumugam M; Simar D; Olofsson LE; Bäckhed F; Barrès R, 2019, 'Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice.', FASEB J, 33, pp. 2719 - 2731, http://dx.doi.org/10.1096/fj.201800787R

Mizrahi D; Fardell JE; Wakefield CE; Simar D; Maguire AM; Hubbard G; Cohn RJ; ANZCHOG survivorship study group , 2019, 'How physically active do Australian and New Zealander childhood cancer survivors perceive themselves? A report from the ANZCHOG survivorship study.', Complement Ther Med, 44, pp. 196 - 203, http://dx.doi.org/10.1016/j.ctim.2019.04.020

Alzahrani J; Hussain T; Simar D; Palchaudhuri R; Abdel-Mohsen M; Crowe SM; Mbogo GW; Palmer CS, 2019, 'Inflammatory and immunometabolic consequences of gut dysfunction in HIV: Parallels with IBD and implications for reservoir persistence and non-AIDS comorbidities.', EBioMedicine, 46, pp. 522 - 531, http://dx.doi.org/10.1016/j.ebiom.2019.07.027

Andersen E; Ingerslev LR; Fabre O; Donkin I; Altıntaş A; Versteyhe S; Bisgaard T; Kristiansen VB; Simar D; Barrès R, 2019, 'Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function.', Int J Obes (Lond), 43, pp. 306 - 318, http://dx.doi.org/10.1038/s41366-018-0031-3

Daniel S; Nylander V; Ingerslev LR; Zhong L; Fabre O; Clifford B; Johnston K; Cohn RJ; Barres R; Simar D, 2018, 'T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors.', Clin Epigenetics, 10, pp. 138, http://dx.doi.org/10.1186/s13148-018-0561-5

Clifford BK; Mizrahi D; Sandler CX; Barry BK; Simar D; Wakefield CE; Goldstein D, 2018, 'Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review.', Support Care Cancer, 26, pp. 685 - 700, http://dx.doi.org/10.1007/s00520-017-3964-5

Fabre O; Ingerslev LR; Garde C; Donkin I; Simar D; Barrès R, 2018, 'Exercise training alters the genomic response to acute exercise in human adipose tissue.', Epigenomics, 10, pp. 1033 - 1050, http://dx.doi.org/10.2217/epi-2018-0039

Ying Lim M; Simar D; Chow S; Hsu K; R. Lewis C; L. Geczy C; S. Thomas P, 2017, 'S100A8, S100A9 and S100A12 Expression in Myeloid Cells from Whole Blood from Patients with Common Lung Diseases', Pulmonary and Critical Care Medicine, 1, pp. 1 - 10, http://dx.doi.org/10.15761/PCCM.1000123

Mizrahi D; Wakefield CE; Fardell JE; Quinn VF; Lim Q; Clifford BK; Simar D; Ness KK; Cohn RJ, 2017, 'Distance-delivered physical activity interventions for childhood cancer survivors: A systematic review and meta-analysis.', Crit Rev Oncol Hematol, 118, pp. 27 - 41, http://dx.doi.org/10.1016/j.critrevonc.2017.08.008

Palmer CS; Duette GA; Wagner MCE; Henstridge DC; Saleh S; Pereira C; Zhou J; Simar D; Lewin SR; Ostrowski M; McCune JM; Crowe SM, 2017, 'Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection.', FEBS Lett, 591, pp. 3319 - 3332, http://dx.doi.org/10.1002/1873-3468.12843

Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The Microbiota and Epigenetic Regulation of T Helper 17/Regulatory T Cells: In Search of a Balanced Immune System.', Front Immunol, 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417

Jacobsen MJ; Mentzel CMJ; Olesen AS; Huby T; Jørgensen CB; Barrès R; Fredholm M; Simar D, 2016, 'Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity', Journal of Diabetes Research, 2016, pp. 1 - 11, http://dx.doi.org/10.1155/2016/8539057

Nylander V; Ingerslev LR; Andersen E; Fabre O; Garde C; Rasmussen M; Citirikkaya K; Bæk J; Christensen GL; Aznar M; Specht L; Simar D; Barrès R, 2016, 'Ionizing Radiation Potentiates High-Fat Diet-Induced Insulin Resistance and Reprograms Skeletal Muscle and Adipose Progenitor Cells.', Diabetes, 65, pp. 3573 - 3584, http://dx.doi.org/10.2337/db16-0364

Raghuraman S; Donkin I; Versteyhe S; Barrès R; Simar D, 2016, 'The Emerging Role of Epigenetics in Inflammation and Immunometabolism.', Trends Endocrinol Metab, 27, pp. 782 - 795, http://dx.doi.org/10.1016/j.tem.2016.06.008

Simpson KA; Mavros Y; Kay S; Meiklejohn J; de Vos N; Wang Y; Guo Q; Zhao R; Climstein M; Baune BT; Blair S; O'Sullivan AJ; Simar D; Singh N; Singh MAF, 2015, 'Graded Resistance Exercise And Type 2 Diabetes in Older adults (The GREAT2DO study): methods and baseline cohort characteristics of a randomized controlled trial.', Trials, 16, pp. 512, http://dx.doi.org/10.1186/s13063-015-1037-y

Martinez D; Palmer C; Simar D; Cameron BA; Nguyen N; Aggarwal V; Lloyd AR; Zekry A, 2015, 'Characterisation of the cytokine milieu associated with the up-regulation of IL-6 and suppressor of cytokine 3 in chronic hepatitis C treatment non-responders.', Liver Int, 35, pp. 463 - 472, http://dx.doi.org/10.1111/liv.12473

Caillaud C; Mechta M; Ainge H; Madsen AN; Ruell P; Mas E; Bisbal C; Mercier J; Twigg S; Mori TA; Simar D; Barrès R, 2015, 'Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats.', J Endocrinol, 225, pp. 77 - 88, http://dx.doi.org/10.1530/JOE-15-0010

Chan YL; Saad S; Simar D; Oliver B; McGrath K; Reyk DV; Bertrand PP; Gorrie C; Pollock C; Chen H, 2015, 'Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams.', Int J Dev Neurosci, 46, pp. 67 - 75, http://dx.doi.org/10.1016/j.ijdevneu.2015.05.009

Simar D; Versteyhe S; Donkin I; Liu J; Hesson L; Nylander V; Fossum A; Barrès R, 2014, 'DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human.', Metabolism, 63, pp. 1188 - 1197, http://dx.doi.org/10.1016/j.metabol.2014.05.014

Chen H; Simar D; Pegg K; Saad S; Palmer C; Morris MJ, 2014, 'Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents.', Diabetologia, 57, pp. 614 - 622, http://dx.doi.org/10.1007/s00125-013-3132-5

Chen H; Simar D; Morris MJ, 2014, 'Maternal obesity impairs brain glucose metabolism and neural response to hyperglycemia in male rat offspring.', J Neurochem, 129, pp. 297 - 303, http://dx.doi.org/10.1111/jnc.12623

Ruell PA; Simar D; Périard JD; Best S; Caillaud C; Thompson MW, 2014, 'Plasma and lymphocyte Hsp72 responses to exercise in athletes with prior exertional heat illness.', Amino Acids, 46, pp. 1491 - 1499, http://dx.doi.org/10.1007/s00726-014-1721-3

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