By Professor David Simar

Book Chapters

Simar D; Caillaud C, 2014, 'Antioxidant supplementation in the elderly and leukocytes', in Preedy VR (ed.), Aging: oxidative stress and dietary antioxidants, Academic Press, pp. 277 - 286, http://www.store.elsevier.com/

Simar D; Caillaud C, 2014, 'Chapter 26 Antioxidant Supplementation in the Elderly and Leukocytes', in Aging, Elsevier, pp. 277 - 287, http://dx.doi.org/10.1016/b978-0-12-405933-7.00026-3

Simar D; Malatesta D; Caillaud C, 2010, 'Ageing', in Connes P; Hue O; Perrey S (ed.), Exercise Physiology: from a cellular to an integrative approach, IOS Press, Amsterdam, The Netherlands, pp. 654 - 670, http://dx.doi.org/10.3233/978-1-60750-497-9-654

Caillaud C; Simar D, 2004, 'Aptitude physique aerobie et age', in Jeandel C; Bernard PL; Seynnes O (ed.), Aptitude physique, sante et vieillissement, Sauramps Medical, Montpellier, France, pp. 57 - 63

Simar D; Malatesta D, 2004, 'Mesure de l'aptitude physique aerobie chez les sujets ages', in Seynnes O; Jeandel C; Bernard PL (ed.), Aptitude physique, sante et vieillissement, Sauramps Medical, Montpellier, France, pp. 65 - 71

Journal articles

Ha L; Wakefield CE; Diaz C; Mizrahi D; Signorelli C; Yacef K; Simar D, 2023, 'Patterns of physical activity and sedentary behavior in child and adolescent cancer survivors assessed using wrist accelerometry: A cluster analysis approach', Health Informatics Journal, 29, http://dx.doi.org/10.1177/14604582231212525

Batten K; Bhattacharya K; Simar D; Broderick C, 2023, 'Exercise testing and prescription in patients with inborn errors of muscle energy metabolism', Journal of Inherited Metabolic Disease, 46, pp. 763 - 777, http://dx.doi.org/10.1002/jimd.12644

Clifford BK; Kaakoush NO; Tedla N; Goldstein D; Simar D, 2023, 'The effect of exercise intensity on the inflammatory profile of cancer survivors: A randomised crossover study', European Journal of Clinical Investigation, 53, pp. e13984, http://dx.doi.org/10.1111/eci.13984

Macdonald E; Amorim N; Hagstrom A; Markovic K; Simar D; Ward R; Clifford B; Hagstrom M, 2023, 'Evaluating the effect of upper-body morbidity on quality of life following primary breast cancer treatment: a systematic review and meta-analysis', Journal of Cancer Survivorship, http://dx.doi.org/10.1007/s11764-023-01395-0

Clifford BK; Amorim N; Kaakoush N; Boysen L; Tedla N; Goldstein D; Hardeman E; Simar D, 2023, 'Irradiation-Induced Dysbiosis: The Compounding Effect ofHigh-Fat Diet on Metabolic and Immune Functions in Mice', International Journal of Molecular Sciences, 24, pp. 5631 - 5631, http://dx.doi.org/10.3390/ijms24065631

Macdonald ER; Clifford BK; Simar D; Ward RE, 2022, 'Ballet after breast cancer: investigating the feasibility and acceptability of a novel 16-week classical ballet intervention for breast cancer survivors', Supportive Care in Cancer, 30, pp. 9909 - 9919, http://dx.doi.org/10.1007/s00520-022-07420-9

Ha L; Wakefield CE; Fardell J; Cohn RJ; Simar D; Signorelli C; Mizrahi D, 2022, 'Parent perceptions of their child’s and their own physical activity after treatment for childhood cancer', Supportive Care in Cancer, 30, pp. 8947 - 8957, http://dx.doi.org/10.1007/s00520-022-07288-9

Ha L; Wakefield CE; Mizrahi D; Diaz C; Cohn RJ; Signorelli C; Yacef K; Simar D, 2022, 'A Digital Educational Intervention With Wearable Activity Trackers to Support Health Behaviors Among Childhood Cancer Survivors: Pilot Feasibility and Acceptability Study', JMIR Cancer, 8, pp. e38367, http://dx.doi.org/10.2196/38367

Zhao RR; Mavros Y; Meiklejohn J; Anderberg KA; Singh N; Kay S; Baker MK; Wang Y; Climstein M; O'Sullivan A; De Vos N; Baune BT; Blair SN; Simar D; Fiatarone Singh MA, 2022, 'Effect of High-Intensity Power Training on Cognitive Function in Older Adults With Type 2 Diabetes: Secondary Outcomes of the GREAT2DO Study', JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 77, http://dx.doi.org/10.1093/gerona/glac090

Clifford BK; Jones MD; Simar D; Barry BK; Goldstein D, 2021, 'The effect of exercise intensity on exercise-induced hypoalgesia in cancer survivors: A randomized crossover trial', Physiological Reports, 9, pp. e15047, http://dx.doi.org/10.14814/phy2.15047

Ha L; Mizrahi D; Cohn RJ; Simar D; Wakefield CE; Signorelli C, 2021, 'Accuracy of perceived physical activity and fitness levels among childhood cancer survivors', Pediatric Blood and Cancer, 68, pp. e29134, http://dx.doi.org/10.1002/pbc.29134

Ha L; Mizrahi D; Wakefield CE; Cohn RJ; Simar D; Signorelli C, 2021, 'The Use of Activity Trackers in Interventions for Childhood Cancer Patients and Survivors: A Systematic Review', Journal of Adolescent and Young Adult Oncology, 10, pp. 1 - 14, http://dx.doi.org/10.1089/jayao.2020.0099

Tapio S; Little MP; Kaiser JC; Impens N; Hamada N; Georgakilas AG; Simar D; Salomaa S, 2021, 'Ionizing radiation-induced circulatory and metabolic diseases', Environment International, 146, pp. 106235, http://dx.doi.org/10.1016/j.envint.2020.106235

Mosalman Haghighi M; Mavros Y; Kay S; Simpson KA; Baker MK; Wang Y; Zhao RR; Meiklejohn J; Climstein M; O’Sullivan AJ; De Vos N; Baune BT; Blair SN; Simar D; Singh N; Schlicht J; Fiatarone Singh MA; O'Sullivan A, 2021, 'The effect of high-intensity power training on habitual, intervention and total physical activity levels in older adults with type 2 diabetes: Secondary outcomes of the great2do randomized controlled trial', Geriatrics (Switzerland), 6, pp. 1 - 14, http://dx.doi.org/10.3390/geriatrics6010015

Mizrahi D; Fardell JE; Cohn RJ; Partin RE; Howell CR; Hudson MM; Robison LL; Ness KK; McBride J; Field P; Wakefield CE; Simar D, 2020, 'The 6-minute walk test is a good predictor of cardiorespiratory fitness in childhood cancer survivors when access to comprehensive testing is limited', International Journal of Cancer, 147, pp. 847 - 855, http://dx.doi.org/10.1002/ijc.32819

Mizrahi D; Wakefield CE; Simar D; Ha L; McBride J; Field P; Cohn RJ; Fardell JE, 2020, 'Barriers and enablers to physical activity and aerobic fitness deficits among childhood cancer survivors', Pediatric Blood and Cancer, 67, pp. e28339, http://dx.doi.org/10.1002/pbc.28339

Amorim NML; Kee A; Coster ACF; Lucas C; Bould S; Daniel S; Weir JM; Mellett NA; Barbour J; Meikle PJ; Cohn RJ; Turner N; Hardeman EC; Simar D, 2020, 'Irradiation impairs mitochondrial function and skeletal muscle oxidative capacity: significance for metabolic complications in cancer survivors', Metabolism: Clinical and Experimental, 103, pp. 154025, http://dx.doi.org/10.1016/j.metabol.2019.154025

Bellamy J; Broderick C; Hardy LL; Simar D; Puusepp-Benazzouz H; Ong N; Silove N, 2020, 'Feasibility of a school-based exercise intervention for children with intellectual disability to reduce cardio-metabolic risk', Journal of Intellectual Disability Research, 64, pp. 7 - 17, http://dx.doi.org/10.1111/jir.12690

Hiam D; Simar D; Laker R; Altintas A; Gibson-Helm M; Fletcher E; Moreno-Asso A; Trewin AJ; Barres R; Stepto NK, 2019, 'Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function', The Journal of Clinical Endocrinology & Metabolism, 104, pp. 6155 - 6170, http://dx.doi.org/10.1210/jc.2019-01015

Alzahrani J; Hussain T; Simar D; Palchaudhuri R; Abdel-Mohsen M; Crowe SM; Mbogo GW; Palmer CS, 2019, 'Inflammatory and immunometabolic consequences of gut dysfunction in HIV: Parallels with IBD and implications for reservoir persistence and non-AIDS comorbidities', EBioMedicine, 46, pp. 522 - 531, http://dx.doi.org/10.1016/j.ebiom.2019.07.027

Mizrahi D; Wakefield CE; Ha LJ; Cohn R; Simar DE; Fardell J, 2019, 'Satisfaction with an exercise physiology consultation after treatment for childhood cancer: An opportunity for healthy lifestyle education', Heart and Mind, 3, pp. 77 - 106, http://dx.doi.org/10.4103/hm.hm_47_19

Mizrahi D; Fardell JE; Wakefield CE; Simar D; Maguire AM; Hubbard G; Cohn RJ; Fardell J; Foreman T; Girgis A; Signorelli C; Ellis S, 2019, 'How physically active do Australian and New Zealander childhood cancer survivors perceive themselves? A report from the ANZCHOG survivorship study', Complementary Therapies in Medicine, 44, pp. 196 - 203, http://dx.doi.org/10.1016/j.ctim.2019.04.020

Hiam D; Patten R; Gibson-Helm M; Moreno-Asso A; McIlvenna L; Levinger I; Harrison C; Moran LJ; Joham A; Parker A; Shorakae S; Simar D; Stepto N, 2019, 'The effectiveness of high intensity intermittent training on metabolic, reproductive and mental health in women with polycystic ovary syndrome: Study protocol for the iHIT- randomised controlled trial', Trials, 20, pp. 221, http://dx.doi.org/10.1186/s13063-019-3313-8

Poupeau A; Garde C; Sulek K; Citirikkaya K; Treebak JT; Arumugam M; Simar D; Olofsson LE; Bäckhed F; Barres R, 2019, 'Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice', The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, pp. 2719 - 2731, http://dx.doi.org/10.1096/fj.201800787R

Daniel S; Nylander V; Ingerslev LR; Zhong L; Fabre O; Clifford B; Johnston K; Cohn R; Barres R; Simar D, 2018, 'T-cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors', Clinical Epigenetics, 10, pp. 138 - 138, http://dx.doi.org/10.1186/s13148-018-0561-5

Fabre O; Ingerslev LR; Garde C; Donkin I; Simar D; Barres R, 2018, 'Exercise training alters the genomic response to acute exercise in human adipose tissue', Epigenomics, 10, pp. 1033 - 1050, http://dx.doi.org/10.2217/epi-2018-0039

Clifford BK; Mizrahi D; Sandler CX; Barry BK; Simar D; Wakefield CE; Goldstein D, 2018, 'Barriers and facilitators of exercise experienced by cancer survivors: a mixed methods systematic review', Supportive Care in Cancer, 26, pp. 685 - 700, http://dx.doi.org/10.1007/s00520-017-3964-5

Andersen E; Ingerslev LR; Fabre O; Donkin I; Altintas A; Versteyhe S; Kristiansen VB; Bisgaard T; Simar D; Barres R, 2018, 'Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function', International Journal of Obesity, 43, pp. 306 - 318, http://dx.doi.org/10.1038/s41366-018-0031-3

Mizrahi D; Wakefield CE; Fardell JE; Quinn VF; Lim Q; Clifford BK; Simar D; Ness KK; Cohn RJ, 2017, 'Distance-delivered physical activity interventions for childhood cancer survivors: A systematic review and meta-analysis', Critical Reviews in Oncology/Hematology, 118, pp. 27 - 41, http://dx.doi.org/10.1016/j.critrevonc.2017.08.008

Palmer CS; Duette GA; Wagner MCE; Henstridge DC; Saleh S; Pereira C; Zhou J; Simar D; Lewin SR; Febbraio MA; Ostrowski M; McCune JM; Crowe SM, 2017, 'Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection', FEBS Letters, 591, pp. 3319 - 3332, http://dx.doi.org/10.1002/1873-3468.12843

Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The microbiota and epigenetic regulation of t helper 17/regulatory T cells: In search of a balanced immune system', Frontiers in Immunology, 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417

Ying Lim M; Simar D; Chow S; Hsu K; R. Lewis C; L. Geczy C; S. Thomas P, 2017, 'S100A8, S100A9 and S100A12 Expression in Myeloid Cells from Whole Blood from Patients with Common Lung Diseases', Pulmonary and Critical Care Medicine, 1, pp. 1 - 10, http://dx.doi.org/10.15761/PCCM.1000123

Nylander V; Ingerslev LR; Andersen E; Fabre O; Garde C; Rasmussen M; Citirikkaya K; Bæk J; Christensen GL; Aznar M; Specht L; Simar D; Barrès R, 2016, 'Ionizing radiation potentiates high-fat diet-induced insulin resistance and reprograms skeletal muscle and adipose progenitor cells', Diabetes, 65, pp. 3573 - 3584, http://dx.doi.org/10.2337/db16-0364

Raghuraman S; Donkin I; Versteyhe S; Barres R; Simar D, 2016, 'The Emerging Role of Epigenetics in Inflammation and Immunometabolism', Trends in Endocrinology and Metabolism, http://dx.doi.org/10.1016/j.tem.2016.06.008

Simpson KA; Mavros Y; Kay S; Meiklejohn J; de Vos N; Wang Y; Guo Q; Zhao R; Climstein M; Baune BT; Blair S; O'Sullivan AJ; Simar D; Singh N; Fiatarone Singh MA, 2015, 'Graded Resistance Exercise And Type 2 Diabetes in Older adults (The GREAT2DO study): methods and baseline cohort characteristics of a randomized controlled trial', Trials, 16, pp. 512 - 512, http://dx.doi.org/10.1186/s13063-015-1037-y

Chan YL; Saad S; Simar D; Oliver B; McGrath K; Reyk DV; Bertrand PP; Gorrie C; Pollock C; Chen H, 2015, 'Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams', International Journal of Developmental Neuroscience, 46, pp. 67 - 75, http://dx.doi.org/10.1016/j.ijdevneu.2015.05.009

Jacobsen MJ; Mentzel CMJ; Olesen AS; Huby T; Jorgensen CB; Barres R; Fredholm M; Simar D, 2015, 'Altered methylation profile of lymphocytes is concordant with perturbation of lipids metabolism and inflammatory response in obesity', Journal of Diabetes Research, 2016, pp. 8539057 - 8539057, http://dx.doi.org/10.1155/2016/8539057

Caillaud C; Mechta M; Ainge H; Madsen AN; Ruell P; Mas E; Bisbal C; Mercier J; Twigg S; Mori TA; Simar D; Barres R, 2015, 'Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats', Journal of Endocrinology, 225, pp. 77 - 88, http://dx.doi.org/10.1530/JOE-15-0010

Simar D; Versteyhe S; Donkin I; Liu J; Hesson L; Nylander V; Fossum A; Barres R, 2014, 'DNA Methylation Is Altered In B And NK Lymphocytes In Obese And Type 2 Diabetic Human', Metabolism: clinical and experimental, 63, pp. 1188 - 1197, http://dx.doi.org/10.1016/j.metabol.2014.05.014

Ruell, PA ; Simar D; Periard, JD ; Best, S ; Caillaud, C ; Thompson, MW , 2014, 'Plasma and lymphocyte Hsp72 responses to exercise in athletes with prior exertional heat illness', Amino Acids, 46, pp. 1491 - 1499, http://dx.doi.org/10.1007/s00726-014-1721-3

Martinez D; Palmer C; Simar D; Cameron B; Nguyen N; Aggarwal V; Lloyd A; Zekry A, 2014, 'Characterization of the cytokine milieu associated with the upregulation of IL-6 and suppressor of cytokine 3 in chronic hepatitis C treatment non-responders', Liver International, http://dx.doi.org/10.1111/liv.12473

Chen H; Simar D; Morris MJ, 2014, 'Maternal obesity impairs brain glucose metabolism and neural response to hyperglycemia in male rat offspring', Journal of Neurochemistry, 129, pp. 297 - 303, http://dx.doi.org/10.1111/jnc.12623

Mavros Y; Kay S; Simpson KA; Baker MK; Wang Y; Zhao RR; Meiklejohn J; Climstein M; O'Sullivan AJ; de Vos N; Baune BT; Blair SN; Simar D; Rooney K; Singh NA; Fiatarone Singh MA, 2014, 'Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training', Journal of Cachexia, Sarcopenia and Muscle, 5, pp. 111 - 120, http://dx.doi.org/10.1007/s13539-014-0134-1

Chen H; Simar D; Pegg K; Saad S; Palmer C; Morris MJ, 2014, 'Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents', Diabetologia, 57, pp. 614 - 622, http://dx.doi.org/10.1007/s00125-013-3132-5

Mavros Y; Anderberg K; Baker M; Wang Y; Zhao R; Meiklejohn J; Climstein M; O Sullivan AJ; De Vos N; Baune B; Simar D; Rooney K; Singh N; Fiatarone Singh M; Kay S; O'Sullivan A, 2013, 'Changes in Insulin Resistance and HbA1c Are Related to Exercise-Mediated Changes in Body Composition in Older Adults With Type 2 Diabetes', Diabetes Care, 36, pp. 2372 - 2379, http://dx.doi.org/10.2337/dc12-2196

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