By Professor David Simon Ziegler

Journal articles

Geoerger B; Marshall LV; Nysom K; Makin G; Bouffet E; Defachelles AS; Amoroso L; Aerts I; Leblond P; Barahona P; Van-Vlerken K; Fu E; Solca F; Lorence RM; Ziegler DS, 2023, 'Afatinib in paediatric patients with recurrent/refractory ErbB-dysregulated tumours: Results of a phase I/expansion trial', European Journal of Cancer, 188, pp. 8 - 19, http://dx.doi.org/10.1016/j.ejca.2023.04.007

Daly R; Hetherington K; Hazell E; Wadling BR; Tyrrell V; Tucker KM; Marshall GM; Ziegler DS; Lau LMS; Trahair TN; O’Brien TA; Collins K; Gifford AJ; Haber M; Pinese M; Malkin D; Cowley MJ; Karpelowsky J; Drew D; Jacobs C; Wakefield CE, 2023, 'Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 13, http://dx.doi.org/10.3390/jpm13071033

Staunton J; Robertson PA; Harris A; Mayoh C; Wong M; Rumford M; Fuentes-Bolanos N; Cowley M; Lau L; Ziegler DS; Barahona P; Manoharan N, 2023, 'HGG-20. NOVEL PAEDIATRIC CASE OF A SPINAL HIGH-GRADE ASTROCYTOMA WITH PILOID FEATURES IN A PATIENT WITH NOONAN SYNDROME', Neuro-Oncology, 25, pp. i44 - i44, http://dx.doi.org/10.1093/neuonc/noad073.169

Kilburn L; Khuong-Quang D-A; Nysom K; Landi D; Ziegler D; Driever PH; Leary S; Bailey S; Van der Lugt J; Perreault S; Waanders A; Baxter P; Witt O; Hargrave D; McCowage G; Zhao X; Da Costa D; Cox M; Manley P; Hansford J, 2023, 'LGG-09. CLINICAL ACTIVITY OF PAN-RAF INHIBITOR TOVORAFENIB IN THE REGISTRATIONAL PEDIATRIC LOW-GRADE GLIOMA ARM OF THE PHASE 2 FIREFLY-1 (PNOC026) STUDY', Neuro-Oncology, 25, pp. i57 - i57, http://dx.doi.org/10.1093/neuonc/noad073.219

Kilburn LB; Khuong-Quang D-A; Nysom K; Landi DB; Ziegler DS; Hernáiz Driever P; Leary S; Bailey S; van der Lugt J; Perreault S; Waanders AJ; Baxter PA; Witt O; Hargrave DR; McCowage GB; Zhao X; Da Costa D; Cox MC; Manley P; Hansford J, 2023, 'Clinical activity of pan-RAF inhibitor tovorafenib in the registrational pediatric low-grade glioma arm of the phase 2 FIREFLY-1 (PNOC026) study.', Journal of Clinical Oncology, 41, pp. 10004 - 10004, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.10004

van Tilburg CM; Kilburn LB; Crotty E; Smith AA; Perreault S; Franson AF; Jabado N; Hoffman LM; Schmidt R; Schouten-van Meeteren AYN; Sehestedt A; Opocher E; Hernáiz Driever P; Avula S; Ziegler DS; Qiu J; Tsao L-P; Manley P; Hargrave DR; Witt O, 2023, 'LOGGIC/FIREFLY-2: A phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.', Journal of Clinical Oncology, 41, pp. TPS10067 - TPS10067, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.tps10067

Gonzales-Aloy E; Ahmed-Cox A; Tsoli M; Ziegler DS; Kavallaris M, 2023, 'From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer', Advanced Drug Delivery Reviews, 196, http://dx.doi.org/10.1016/j.addr.2023.114777

Sun CX; Daniel P; Bradshaw G; Shi H; Loi M; Chew N; Parackal S; Tsui V; Liang Y; Koptyra M; Adjumain S; Sun C; Chong WC; Fernando D; Drinkwater C; Tourchi M; Habarakada D; Sooraj D; Carvalho D; Storm PB; Baubet V; Sayles LC; Fernandez E; Nguyen T; Pörksen M; Doan A; Crombie DE; Panday M; Zhukova N; Dun MD; Ludlow LE; Day B; Stringer BW; Neeman N; Rubens JA; Raabe EH; Vinci M; Tyrrell V; Fletcher JI; Ekert PG; Dumevska B; Ziegler DS; Tsoli M; Syed Sulaiman NF; Loh AHP; Low SYY; Sweet-Cordero EA; Monje M; Resnick A; Jones C; Downie P; Williams B; Rosenbluh J; Gough D; Cain JE; Firestein R, 2023, 'Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities', Cancer Cell, 41, pp. 660 - 677.e7, http://dx.doi.org/10.1016/j.ccell.2023.03.007

Hayden E; Franshaw L; Upton D; Liu J; Nguyen H; Joshi S; Tsoli M; Dolman E; Rayner B; Ziegler D, 2023, 'Abstract 1561: Preclinical examination of PLK1 inhibitors for the treatment of diffuse midline gliomas', Cancer Research, 83, pp. 1561 - 1561, http://dx.doi.org/10.1158/1538-7445.am2023-1561

Trinder SM; McKay C; Power P; Topp M; Chan B; Valvi S; McCowage G; Govender D; Kirby M; Ziegler DS; Manoharan N; Hassall T; Kellie S; Heath J; Alvaro F; Wood P; Laughton S; Tsui K; Dodgshun A; Eisenstat DD; Endersby R; Luen SJ; Koh ES; Sim HW; Kong B; Gottardo NG; Whittle JR; Khuong-Quang DA; Hansford JR, 2023, 'BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience', Frontiers in Oncology, 13, http://dx.doi.org/10.3389/fonc.2023.1154246

Whitehouse JP; Hii H; Mayoh C; Wong M; Ajuyah P; Barahona P; Cui L; Dholaria H; White CL; Buntine MK; Byrne J; Rodrigues da Silva K; Howlett M; Girard EJ; Tsoli M; Ziegler DS; Dyke JM; Lee S; Ekert PG; Cowley MJ; Gottardo NG; Endersby R, 2023, 'In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma', Frontiers in Oncology, 13, http://dx.doi.org/10.3389/fonc.2023.1123492

Ehteda A; Khan A; Rajakumar G; Vanniasinghe AS; Gopalakrishnan A; Liu J; Tsoli M; Ziegler DS, 2023, 'Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas', Molecular Cancer Therapeutics, 22, pp. 1413 - 1421, http://dx.doi.org/10.1158/1535-7163.MCT-23-0179

Lilly JV; Rokita JL; Mason JL; Patton T; Stefankiewiz S; Higgins D; Trooskin G; Larouci CA; Arya K; Appert E; Heath AP; Zhu Y; Brown MA; Zhang B; Farrow BK; Robins S; Morgan AM; Nguyen TQ; Frenkel E; Lehmann K; Drake E; Sullivan C; Plisiewicz A; Coleman N; Patterson L; Koptyra M; Helili Z; Van Kuren N; Young N; Kim MC; Friedman C; Lubneuski A; Blackden C; Williams M; Baubet V; Tauhid L; Galanaugh J; Boucher K; Ijaz H; Cole KA; Choudhari N; Santi M; Moulder RW; Waller J; Rife W; Diskin SJ; Mateos M; Parsons DW; Pollack IF; Goldman S; Leary S; Caporalini C; Buccoliero AM; Scagnet M; Haussler D; Hanson D; Firestein R; Cain J; Phillips JJ; Gupta N; Mueller S; Grant G; Monje-Deisseroth M; Partap S; Greenfield JP; Hashizume R; Smith A; Zhu S; Johnston JM; Fangusaro JR; Miller M; Wood MD; Gardner S; Carter CL; Prolo LM; Pisapia J; Pehlivan K; Franson A; Niazi T; Rubin J; Abdelbaki M; Ziegler DS; Lindsay HB; Stucklin AG; Gerber N; Vaske OM; Quinsey C; Rood BR; Nazarian J; Raabe E; Jackson EM; Stapleton S; Lober RM; Kram DE; Koschmann C; Storm PB; Lulla RR; Prados M; Resnick AC; Waanders AJ, 2023, 'The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science', Neoplasia (United States), 35, http://dx.doi.org/10.1016/j.neo.2022.100846

Lehmann R; Rayner BS; Ziegler DS, 2022, 'Resistance mechanisms in BRAF^V600E paediatric high-grade glioma and current therapeutic approaches', Frontiers in Oncology, 12, http://dx.doi.org/10.3389/fonc.2022.1031378

Bartlett AL; Lane A; Chaney B; Escorza NY; Black K; Cochrane A; Minturn J; Bartels U; Warren K; Hansford J; Ziegler D; Diez B; Goldman S; Packer R; Kieran M; DeWire-Schottmiller M; Erker C; Monje-Deisseroth M; Wagner L; Koschmann C; Dorris K; Shih CS; Hassall T; Samson Y; Fisher P; Wang SS; Tsui K; Sevlever G; Zhu X; Dexheimer P; Asher A; Fuller C; Drissi R; Jones B; Leach J; Fouladi M, 2022, 'Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry', Neuro-Oncology, 24, pp. 2190 - 2199, http://dx.doi.org/10.1093/neuonc/noac123

Burke MJ; Ziegler DS; Bautista F; Attarbaschi A; Gore L; Locatelli F; M. O'Brien M; Pauly M; Kormany WN; Tian S; Morris CL; Baruchel A, 2022, 'Phase 1b study of carfilzomib with induction chemotherapy in pediatric relapsed/refractory acute lymphoblastic leukemia', Pediatric Blood and Cancer, 69, http://dx.doi.org/10.1002/pbc.29999

van Tilburg C; Jones DT; Schmidt R; Avula S; van Meeteren AS; Sehested A; Opocher E; Driever PH; Witt R; Ziegler D; Blackman S; Zhao X; Tsao L-P; Cox M; Hargrave D; Witt O, 2022, 'CTNI-30. LOGGIC/FIREFLY-2: A PHASE 3, RANDOMIZED TRIAL OF TOVORAFENIB VS. CHEMOTHERAPY IN PEDIATRIC PATIENTS WITH NEWLY DIAGNOSED LOW-GRADE GLIOMA HARBORING AN ACTIVATING RAF ALTERATION', Neuro-Oncology, 24, pp. vii77 - vii78, http://dx.doi.org/10.1093/neuonc/noac209.295

Whitlock JA; Malvar J; Dalla-Pozza L; Goldberg JM; Silverman LB; Ziegler DS; Attarbaschi A; Brown PA; Gardner RA; Gaynon PS; Hutchinson R; Huynh VT; Jeha S; Marcus L; Messinger Y; Schultz KR; Cassar J; Locatelli F; Zwaan CM; Wood BL; Sposto R; Gore L, 2022, 'Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR)', Pediatric Blood and Cancer, 69, http://dx.doi.org/10.1002/pbc.29901

Gereis J; Hetherington K; Ha L; Robertson EG; Ziegler DS; Barlow-Stewart K; Tucker KM; Marron JM; Wakefield CE, 2022, 'Parents’ understanding of genome and exome sequencing for pediatric health conditions: a systematic review', European Journal of Human Genetics, 30, pp. 1216 - 1225, http://dx.doi.org/10.1038/s41431-022-01170-2

Hetherington K; Wakefield CE; Kunalan KPK; Donoghoe MW; McGill BC; Fardell JE; Daly R; Deyell RJ; Ziegler DS, 2022, 'Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer', Cancers, 14, http://dx.doi.org/10.3390/cancers14215310

Gargett T; Ebert LM; Truong NTH; Kollis PM; Sedivakova K; Yu W; Yeo ECF; Wittwer NL; Gliddon BL; Tea MN; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler DS; Pitson SM; Brown MP, 2022, 'GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma', Journal for ImmunoTherapy of Cancer, 10, http://dx.doi.org/10.1136/jitc-2022-005187

Tsai JW; Cejas P; Wang DK; Patel S; Wu DW; Arounleut P; Wei X; Zhou N; Syamala S; Dubois FPB; Crane A; Pelton K; Vogelzang J; Sousa C; Baguette A; Chen X; Condurat AL; Dixon-Clarke SE; Zhou KN; Lu SD; Gonzalez EM; Chacon MS; Digiacomo JJ; Kumbhani R; Novikov D; Hunter J; Tsoli M; Ziegler DS; Dirksen U; Jager N; Balasubramanian GP; Kramm CM; Nathrath M; Bielack S; Baker SJ; Zhang J; McFarland JM; Getz G; Aguet F; Jabado N; Witt O; Pfister SM; Ligon KL; Hovestadt V; Kleinman CL; Long H; Jones DTW; Bandopadhayay P; Phoenix TN, 2022, 'FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits', Cancer Research, 82, pp. 2980 - 3001, http://dx.doi.org/10.1158/0008-5472.CAN-22-0671

Deblois S; Zhu L; Mastropasqua B; Thibaudeau S; Ziegler D; Pomp A, 2022, 'The clinical effectiveness and safety of intravenous unfractionated heparin following digital replantation and revascularization: A narrative systematic review', Microsurgery, 42, pp. 622 - 630, http://dx.doi.org/10.1002/micr.30895

Lazow MA; Nievelstein MT; Lane A; Bandopadhayhay P; DeWire-Schottmiller M; Fouladi M; Glod JW; Greiner RJ; Hoffman LM; Hummel TR; Kilburn L; Leary S; Minturn JE; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach JL, 2022, 'Volumetric endpoints in diffuse intrinsic pontine glioma: p correlations in the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 1598 - 1608, http://dx.doi.org/10.1093/neuonc/noac037

Sacks E; Finlayson K; Brizuela V; Crossland N; Ziegler D; Sauvé C; Langlois ÉV; Javadi D; Downe S; Bonet M, 2022, 'Factors that influence uptake of routine postnatal care: Findings on women’s perspectives from a qualitative evidence synthesis', PLoS ONE, 17, http://dx.doi.org/10.1371/journal.pone.0270264

Hunter JD; Robertson EG; Hetherington K; Ziegler DS; Marshall GM; Kirk J; Marron JM; Denburg AE; Barlow-Stewart K; Warby M; Tucker KM; Lee BM; O’Brien TA; Wakefield CE; O'Brien T, 2022, 'What’s in a Name? Parents’ and Healthcare Professionals’ Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes', Journal of Personalized Medicine, 12, pp. 1327, http://dx.doi.org/10.3390/jpm12081327

Lamoureux A-A; Fisher M; Lemelle L; Pfaff E; Kramm C; De Wilde B; Kazanowska B; Hutter C; Pfister SM; Sturm D; Jones D; Orbach D; Pierron G; Raskin S; Drilon A; Diamond E; Harada G; Zapotocky M; Ellezam B; Weil AG; Venne D; Barritault M; Leblond P; Coltin H; Hammad R; Tabori U; Hawkins C; Hansford JR; Meyran D; Erker C; McFadden K; Sato M; Gottardo NG; Dholaria H; Nørøxe DS; Goto H; Ziegler DS; Lin FY; Parsons DW; Lindsay H; Wong T-T; Liu Y-L; Wu K-S; Franson AF; Hwang E; Aguilar-Bonilla A; Cheng S; Cacciotti C; Massimino M; Schiavello E; Wood P; Hoffman LM; Cappellano A; Lassaletta A; Van Damme A; Llort A; Gerber NU; Ceruso MS; Bendel AE; Skrypek M; Hamideh D; Mushtaq N; Walter A; Jabado N; Alsahlawi A; Farmer J-P; Abadi CC; Mueller S; Mazewski C; Aguilera D; Robison N; O’Halloran K; Abbou S; Berlanga P; Geoerger B; Øra I; Moertel CL; Razis ED; Vernadou A; Doz F; Laetsch TW; Perreault S, 2022, 'HGG-11. Clinical characteristics and clinical evolution of a large cohort of pediatric patients with primary central nervous system (CNS) tumors and tropomyosin receptor kinase (TRK) fusion.', Neuro-Oncology, 24, pp. i61 - i62, http://dx.doi.org/10.1093/neuonc/noac079.226

Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Nguyen H; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'MODL-17. The Childhood Brain Cancer Cell Line Atlas: A Resource for Biomarker Identification and Therapeutic Development', Neuro-Oncology, 24, pp. i172 - i172, http://dx.doi.org/10.1093/neuonc/noac079.640

Kong BY; Carter C; Nowak AK; Hovey E; Lwin Z; Haghighi N; Gan HK; Sim HW; Ziegler DS; Barton K; Parkinson J; Leonard R; Khasraw M; Foote M, 2022, 'Barriers and potential solutions to international collaboration in neuro-oncology clinical trials: Challenges from the Australian perspective', Asia-Pacific Journal of Clinical Oncology, 18, pp. 259 - 266, http://dx.doi.org/10.1111/ajco.13606

Doz F; Van Tilburg CM; Geoerger B; Højgaard M; Øra I; Boni V; Capra M; Chisholm J; Chung HC; Dubois SG; Gallego-Melcon S; Gerber NU; Goto H; Grilley-Olson JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Nysom K; Thorwarth A; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2022, 'Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors', Neuro-Oncology, 24, pp. 997 - 1007, http://dx.doi.org/10.1093/neuonc/noab274

Lazow MA; Fuller C; Dewire M; Lane A; Bandopadhayay P; Bartels U; Bouffet E; Cheng S; Cohen KJ; Cooney TM; Coven SL; Dholaria H; Diez B; Dorris K; El-Ayadi M; El-Sheikh A; Fisher PG; Fonseca A; Garcia Lombardi M; Greiner RJ; Goldman S; Gottardo N; Gururangan S; Hansford JR; Hassall T; Hawkins C; Kilburn L; Koschmann C; Leary SE; Ma J; Minturn JE; Monje-Deisseroth M; Packer R; Samson Y; Sandler ES; Sevlever G; Tinkle CL; Tsui K; Wagner LM; Zaghloul M; Ziegler DS; Chaney B; Black K; Asher A; Drissi R; Fouladi M; Jones BV; Leach JL, 2022, 'Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry', Neuro-Oncology, 24, pp. 821 - 833, http://dx.doi.org/10.1093/neuonc/noab245

Pommert L; Schafer ES; Malvar J; Gossai N; Florendo E; Pulakanti K; Heimbruch K; Stelloh C; Chi YY; Sposto R; Rao S; Huynh VT; Brown P; Chang BH; Colace SI; Hermiston ML; Heym K; Hutchinson RJ; Kaplan JA; Mody R; O'Brien TA; Place AE; Shaw PH; Ziegler DS; Wayne A; Bhojwani D; Burke MJ, 2022, 'Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium', American Journal of Hematology, 97, pp. 613 - 622, http://dx.doi.org/10.1002/ajh.26510

Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM; Trahair T, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. e14608, http://dx.doi.org/10.15252/emmm.202114608

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682

Erker C; Lane A; Chaney B; Leary S; Minturn JE; Bartels U; Packer RJ; Dorris K; Gottardo NG; Warren KE; Broniscer A; Kieran MW; Zhu X; White P; Dexheimer PJ; Black K; Asher A; Dewire M; Hansford JR; Gururangan S; Nazarian J; Ziegler DS; Sandler E; Bartlett A; Goldman S; Shih CS; Hassall T; Dholaria H; Bandopadhayay P; Samson Y; Monje M; Fisher PG; Dodgshun A; Parkin S; Chintagumpala M; Tsui K; Gass D; Larouche V; Broxson E; Garcia Lombardi M; Wang SS; Ma J; Hawkins C; Hamideh D; Wagner L; Koschmann C; Fuller C; Drissi R; Jones BV; Leach J; Fouladi M, 2022, 'Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry', Neuro-Oncology, 24, pp. 141 - 152, http://dx.doi.org/10.1093/neuonc/noab140

Das A; Sudhaman S; Morgenstern D; Coblentz A; Chung J; Stone SC; Alsafwani N; Liu ZA; Karsaneh OAA; Soleimani S; Ladany H; Chen D; Zatzman M; Cabric V; Nobre L; Bianchi V; Edwards M; Sambira Nahum LC; Ercan AB; Nabbi A; Constantini S; Dvir R; Yalon-Oren M; Campino GA; Caspi S; Larouche V; Reddy A; Osborn M; Mason G; Lindhorst S; Bronsema A; Magimairajan V; Opocher E; De Mola RL; Sabel M; Frojd C; Sumerauer D; Samuel D; Cole K; Chiaravalli S; Massimino M; Tomboc P; Ziegler DS; George B; Van Damme A; Hijiya N; Gass D; McGee RB; Mordechai O; Bowers DC; Laetsch TW; Lossos A; Blumenthal DT; Sarosiek T; Yen LY; Knipstein J; Bendel A; Hoffman LM; Luna-Fineman S; Zimmermann S; Scheers I; Nichols KE; Zapotocky M; Hansford JR; Maris JM; Dirks P; Taylor MD; Kulkarni AV; Shroff M; Tsang DS; Villani A; Xu W; Aronson M; Durno C; Shlien A; Malkin D; Getz G; Maruvka YE; Ohashi PS; Hawkins C; Pugh TJ; Bouffet E; Tabori U, 2022, 'Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency', Nature Medicine, 28, pp. 125 - 135, http://dx.doi.org/10.1038/s41591-021-01581-6

Fischer M; Moreno L; Ziegler DS; Marshall LV; Zwaan CM; Irwin MS; Casanova M; Sabado C; Wulff B; Stegert M; Wang L; Hurtado FK; Branle F; Geoerger B; Schulte JH, 2021, 'Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study', The Lancet Oncology, 22, pp. 1764 - 1776, http://dx.doi.org/10.1016/S1470-2045(21)00536-2

Manoharan N; Ajuyah P; Senapati A; Wong M; Mullins A; Rodriguez M; Doyle H; McCowage G; Lau LMS; Ekert PG; Ziegler DS, 2021, 'Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis', Acta Neuropathologica Communications, 9, http://dx.doi.org/10.1186/s40478-021-01248-w

Khan A; Gamble LD; Upton DH; Ung C; Yu DMT; Ehteda A; Pandher R; Mayoh C; Hébert S; Jabado N; Kleinman CL; Burns MR; Norris MD; Haber M; Tsoli M; Ziegler DS, 2021, 'Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas', Nature Communications, 12, pp. 971, http://dx.doi.org/10.1038/s41467-021-20896-z

Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', npj Precision Oncology, 5, http://dx.doi.org/10.1038/s41698-021-00145-8

Goudie C; Witkowski L; Cullinan N; Reichman L; Schiller I; Tachdjian M; Armstrong L; Blood KA; Brossard J; Brunga L; Cacciotti C; Caswell K; Cellot S; Clark ME; Clinton C; Coltin H; Felton K; Fernandez CV; Fleming AJ; Fuentes-Bolanos N; Gibson P; Grant R; Hammad R; Harrison LW; Irwin MS; Johnston DL; Kane S; Lafay-Cousin L; Lara-Corrales I; Larouche V; Mathews N; Meyn MS; Michaeli O; Perrier R; Pike M; Punnett A; Ramaswamy V; Say J; Somers G; Tabori U; Thibodeau ML; Toupin AK; Tucker KM; Van Engelen K; Vairy S; Waespe N; Warby M; Wasserman JD; Whitlock JA; Sinnett D; Jabado N; Nathan PC; Shlien A; Kamihara J; Deyell RJ; Ziegler DS; Nichols KE; Dendukuri N; Malkin D; Villani A; Foulkes WD, 2021, 'Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes', JAMA Oncology, 7, pp. 1806 - 1814, http://dx.doi.org/10.1001/jamaoncol.2021.4536

Hayden E; Holliday H; Lehmann R; Khan A; Tsoli M; Rayner BS; Ziegler DS, 2021, 'Therapeutic targets in diffuse midline gliomas—an emerging landscape', Cancers, 13, http://dx.doi.org/10.3390/cancers13246251

Doz F; van Tilburg CM; Geoerger B; Nysom K; Øra I; Boni V; Chisholm J; Chung HC; DuBois SG; Melcón SG; Gerber NU; Goto H; Grilley-Olsen JE; Hansford JR; Hong DS; Italiano A; Kang HJ; Capra M; Schulte JH; Stefanowicz J; Tahara M; Ziegler DS; Gavrilovic IT; Norenberg R; Dima L; De La Cuesta E; Laetsch TW; Drilon A; Perreault S, 2021, 'CTNI-58. EFFICACY AND SAFETY OF LAROTRECTINIB IN ADULT AND PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS', Neuro-Oncology, 23, pp. vi73 - vi74, http://dx.doi.org/10.1093/neuonc/noab196.283

Lazow M; Nievelstein M; Lane A; Bandopadhayay P; DeWire-Schottmiller M; Fouladi M; Glod J; Greiner R; Hoffman L; Hummel T; Kilburn L; Leary S; Minturn J; Packer R; Ziegler DS; Chaney B; Black K; de Blank P; Leach J, 2021, 'NIMG-11. VOLUMETRIC ENDPOINTS IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): COMPARISON TO CROSS-SECTIONAL MEASURES AND CORRELATION WITH OUTCOMES', Neuro-Oncology, 23, pp. vi129 - vi130, http://dx.doi.org/10.1093/neuonc/noab196.511

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Meyran D; Terry RL; Zhu JJ; Haber M; Ziegler DS; Ekert PG; Trapani JA; Darcy PK; Neeson PJ, 2021, 'Early-phenotype CAR-T cells for the treatment of pediatric cancers', Annals of Oncology, 32, pp. 1366 - 1380, http://dx.doi.org/10.1016/j.annonc.2021.07.018

Terry RL; Meyran D; Fleuren EDG; Mayoh C; Zhu J; Omer N; Ziegler DS; Haber M; Darcy PK; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Chimeric antigen receptor t cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma', Cancers, 13, pp. 4704, http://dx.doi.org/10.3390/cancers13184704

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