Select Publications
Journal articles
, 2024, 'Increased frequency of CHEK2 germline pathogenic variants among individuals with dermatofibrosarcoma protuberans', Genetics in Medicine Open, 2, http://dx.doi.org/10.1016/j.gimo.2024.101895
, 2024, '282P Nivolumab and ipilimumab combination treatment in advanced intrahepatic cholangiocarcinoma and gallbladder cancer', Annals of Oncology, 35, pp. S119 - S119, http://dx.doi.org/10.1016/j.annonc.2024.05.288
, 2024, '998MO Nivolumab and ipilimumab combination treatment in advanced dMMR/MSI-H noncolorectal cancers: Results from the phase II MoST-CIRCUIT study', Annals of Oncology, 35, pp. S679 - S680, http://dx.doi.org/10.1016/j.annonc.2024.08.1057
, 2024, 'Computational repurposing of oncology drugs through off-target drug binding interactions from pharmacological databases', CLINICAL AND TRANSLATIONAL MEDICINE, 14, http://dx.doi.org/10.1002/ctm2.1657
, 2024, 'Nivolumab and ipilimumab combination treatment in advanced gynaecological clear cell cancers: Results from the phase II MoST-CIRCUIT trial', ANNALS OF ONCOLOGY, 35, pp. S546 - S547, http://dx.doi.org/10.1016/j.annonc.2024.08.775
, 2023, 'A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content', Npj Genomic Medicine, 8, http://dx.doi.org/10.1038/s41525-023-00369-6
, 2023, 'Precision medicine: affording the successes of science', Npj Precision Oncology, 7, http://dx.doi.org/10.1038/s41698-022-00343-y
, 2023, 'Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype', Oncogene, 42, pp. 3529 - 3541, http://dx.doi.org/10.1038/s41388-023-02864-7
, 2023, 'PATH-25. EXPLORING THE PROGNOSTIC IMPLICATIONS OF MOLECULAR ALTERATIONS IN ASTROCYTOMAS USING COMPREHENSIVE GENOMIC PROFILING (CGP)', Neuro-Oncology, 25, pp. v173 - v173, http://dx.doi.org/10.1093/neuonc/noad179.0655
, 2023, 'Modified study designs to expand treatment options in personalised oncology: a multistakeholder view', European Journal of Cancer, 194, http://dx.doi.org/10.1016/j.ejca.2023.113278
, 2023, 'Myelodysplastic syndrome and multiple solid tumours in an individual with compound heterozygous deleterious FANCM variants: A case report and review of the literature', British Journal of Haematology, 203, pp. 481 - 484, http://dx.doi.org/10.1111/bjh.19059
, 2023, 'Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials', International Journal of Cancer, 153, pp. 1413 - 1422, http://dx.doi.org/10.1002/ijc.34649
, 2023, 'Family communication and results disclosure after germline sequencing: A mixed methods study', Patient Education and Counseling, 114, http://dx.doi.org/10.1016/j.pec.2023.107800
, 2023, 'Implementation of the Australasian Teletrial Model: Translating ideas into action using implementation science frameworks', Journal of Telemedicine and Telecare, 29, pp. 641 - 647, http://dx.doi.org/10.1177/1357633X211017805
, 2023, 'A signal-seeking Phase 2 study of olaparib and durvalumab in advanced solid cancers with homologous recombination repair gene alterations', British Journal of Cancer, 129, pp. 475 - 485, http://dx.doi.org/10.1038/s41416-023-02311-0
, 2023, 'Clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials.', Journal of Clinical Oncology, 41, pp. 3101 - 3101, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.3101
, 2023, 'Genomic alterations associated with response to immune checkpoint inhibitors in rare cancers: A biomarker exploration study from the Australian Molecular Screening and Therapeutics (MoST) Program.', Journal of Clinical Oncology, 41, pp. 2594 - 2594, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.2594
, 2023, 'Genomic targetability and survival outcomes of biliary tract cancers (BTC): A retrospective cohort study of the Australian Molecular Screening and Therapeutics (MoST) program', JOURNAL OF CLINICAL ONCOLOGY, 41, http://dx.doi.org/10.1200/JCO.2023.41.16_suppl.4093
, 2023, 'Genomic therapy matching in rare and refractory cancers: Updated results from a retrospective cohort study in the Molecular Screening and Therapeutic (MoST) program', JOURNAL OF CLINICAL ONCOLOGY, 41, http://dx.doi.org/10.1200/JCO.2023.41.16_suppl.1540
, 2023, 'Long-term clinical and psychosocial outcomes of surveillance in Li Fraumeni syndrome.', Journal of Clinical Oncology, 41, pp. 10578 - 10578, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.10578
, 2023, 'Molecular tumor profiling and therapy selection in advanced gynecological cancers: A retrospective cohort analysis from the Australian Molecular Screening and Therapeutics (MoST) Program', JOURNAL OF CLINICAL ONCOLOGY, 41, http://dx.doi.org/10.1200/JCO.2023.41.16_suppl.5526
, 2023, 'Trastuzumab emtansine (T-DM1) in advanced cancers with HER2 mutations or amplification: Results from the Molecular Screening and Therapeutics (MoST) Program substudy.', Journal of Clinical Oncology, 41, pp. 3127 - 3127, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.3127
, 2023, 'Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare', American Journal of Human Genetics, 110, pp. 419 - 426, http://dx.doi.org/10.1016/j.ajhg.2023.01.018
, 2023, 'Early circulating tumor DNA dynamics as a pan-tumor biomarker for long-term clinical outcome in patients treated with durvalumab and tremelimumab', Molecular Oncology, 17, pp. 298 - 311, http://dx.doi.org/10.1002/1878-0261.13349
, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', Science, 379, pp. 253 - 260, http://dx.doi.org/10.1126/science.abj4784
, 2022, 'Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients with Cancer: A Narrative Review', JAMA Oncology, 8, pp. 1830 - 1839, http://dx.doi.org/10.1001/jamaoncol.2022.4457
, 2022, 'Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers', Asia Pacific Journal of Clinical Oncology, 18, pp. 660 - 668, http://dx.doi.org/10.1111/ajco.13745
, 2022, 'Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-30496-0
, 2022, 'Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments', Cancer Treatment Reviews, 110, http://dx.doi.org/10.1016/j.ctrv.2022.102455
, 2022, 'Effective and Efficient Delivery of Genome-Based Testing-What Conditions Are Necessary for Health System Readiness?', Healthcare Switzerland, 10, http://dx.doi.org/10.3390/healthcare10102086
, 2022, 'Return of comprehensive tumour genomic profiling results to advanced cancer patients: a qualitative study', Supportive Care in Cancer, 30, pp. 8201 - 8210, http://dx.doi.org/10.1007/s00520-022-07272-3
, 2022, 'Using whole-genome sequencing to characterize clinically significant blood groups among healthy older Australians', Blood Advances, 6, pp. 4593 - 4604, http://dx.doi.org/10.1182/bloodadvances.2022007505
, 2022, 'Preferences for return of germline genome sequencing results for cancer patients and their genetic relatives in a research setting', European Journal of Human Genetics, 30, pp. 930 - 937, http://dx.doi.org/10.1038/s41431-022-01069-y
, 2022, 'Psychological impact of comprehensive tumor genomic profiling results for advanced cancer patients', Patient Education and Counseling, 105, pp. 2206 - 2216, http://dx.doi.org/10.1016/j.pec.2022.01.011
, 2022, 'Challenges of Conducting Value Assessment for Comprehensive Genomic Profiling', International Journal of Technology Assessment in Health Care, 38, http://dx.doi.org/10.1017/S026646232200040X
, 2022, 'Psychological predictors of cancer patients' and their relatives’ attitudes towards the return of genomic sequencing results', European Journal of Medical Genetics, 65, http://dx.doi.org/10.1016/j.ejmg.2022.104516
, 2022, 'Unlocking Access to Broad Molecular Profiling: Benefits, Barriers, and Policy Solutions', Public Health Genomics, 25, pp. 70 - 79, http://dx.doi.org/10.1159/000520000
, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. emmm202114608, http://dx.doi.org/10.15252/emmm.202114608
, 2022, 'Population DNA screening for medically actionable disease risk in adults', Medical Journal of Australia, 216, pp. 278 - 280, http://dx.doi.org/10.5694/mja2.51454
, 2022, 'Delivering precision oncology to patients with cancer', Nature Medicine, 28, pp. 658 - 665, http://dx.doi.org/10.1038/s41591-022-01717-2
, 2022, 'Cancer patient knowledge about and behavioral intentions after germline genome sequencing', Patient Education and Counseling, 105, pp. 707 - 718, http://dx.doi.org/10.1016/j.pec.2021.07.004
, 2022, 'Psychological predictors of advanced cancer patients’ preferences for return of results from comprehensive tumor genomic profiling', American Journal of Medical Genetics Part A, 188, pp. 725 - 734, http://dx.doi.org/10.1002/ajmg.a.62563
, 2022, 'Effectively communicating comprehensive tumor genomic profiling results: Mitigating uncertainty for advanced cancer patients', Patient Education and Counseling, 105, pp. 452 - 459, http://dx.doi.org/10.1016/j.pec.2021.05.018
, 2022, 'Rare germline variants in childhood cancer patients suspected of genetic predisposition to cancer', Genes Chromosomes and Cancer, 61, pp. 81 - 93, http://dx.doi.org/10.1002/gcc.23006
, 2022, 'Value of whole-genome sequencing to Australian cancer patients and their first-degree relatives participating in a genomic sequencing study', Journal of Genetic Counseling, 31, pp. 96 - 108, http://dx.doi.org/10.1002/jgc4.1455
, 2022, 'Clinical Response to Seribantumab, an Anti-Human Epidermal Growth Factor Receptor-3 Immunoglobulin 2 Monoclonal Antibody, in a Patient With Metastatic Pancreatic Ductal Adenocarcinoma Harboring an NRG1 Fusion', JCO PRECISION ONCOLOGY, 6, http://dx.doi.org/10.1200/PO.22.00263
, 2022, 'Psychological Outcomes in Advanced Cancer Patients After Receiving Genomic Tumor Profiling Results', Health Psychology, 41, pp. 396 - 408, http://dx.doi.org/10.1037/hea0001181
, 2022, '1487MO A pan-sarcoma investigation of genetic alterations associated with high telomeric content', Annals of Oncology, 33, pp. S1226 - S1227, http://dx.doi.org/10.1016/j.annonc.2022.07.1590
, 2022, 'Questioning the ethics of evidence-based practice for Indigenous health and social settings in Australia', BMJ GLOBAL HEALTH, 7, http://dx.doi.org/10.1136/bmjgh-2022-009167
, 2021, 'ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data', Genome Medicine, 13, pp. 32, http://dx.doi.org/10.1186/s13073-021-00841-x