By Professor David Thomas

Journal articles

Thomas DM; Wilhelm M; Cleton-Jansen A-M; Dirksen U; Entz-Werle N; Gelderblom H; Hassan B; Juergens H; Koster J; Kovar H; Lankester AC; Lewis IJ; Myklebost O; Nathrath MHM; Picci P; Whelan JS; Hogendoorn PCW; Bielack SS, 2011, 'Workshop Report on the European Bone Sarcoma Networking Meeting: Integration of Clinical Trials with Tumor Biology', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, 1, pp. 118 - 123, http://dx.doi.org/10.1089/jayao.2012.0005

Clark JCM; Akiyama T; Thomas DM; Labrinidis A; Evdokiou A; Galloway SJ; Kim HS; Dass CR; Choong PFM, 2011, 'RECK in osteosarcoma: A novel role in tumour vasculature and inhibition of tumorigenesis in an orthotopic model', Cancer, 117, pp. 3517 - 3528, http://dx.doi.org/10.1002/cncr.25757

Blanke CD; Bot BM; Thomas DM; Bleyer A; Kohne CH; Seymour MT; De Gramont A; Goldberg RM; Sargent DJ, 2011, 'Impact of young age on treatment efficacy and safety in advanced colorectal cancer: A pooled analysis of patients from nine first-line phase III chemotherapy trials', Journal of Clinical Oncology, 29, pp. 2781 - 2786, http://dx.doi.org/10.1200/JCO.2010.33.5281

Thomas DM, 2011, 'Lessons from the deep study of rare tumours', Journal of Pathology, 224, pp. 306 - 308, http://dx.doi.org/10.1002/path.2928

Blay J; Chawla SP; Martin Broto J; Choy E; Dominkus M; Engellau J; Grimer R; Henshaw RM; Palmerini E; Reichardt P; Rutkowski P; Skubitz KM; Thomas DM; Zhao Y; Qian Y; Jacobs IA, 2011, 'Denosumab safety and efficacy in giant cell tumor of bone (GCTB): Interim results from a phase II study.', Journal of Clinical Oncology, 29, pp. 10034 - 10034, http://dx.doi.org/10.1200/jco.2011.29.15_suppl.10034

Thomas D; Moore A, 2011, 'Counterpoints in cancer: The somatic mutation theory under attack', BioEssays, 33, pp. 313 - 314, http://dx.doi.org/10.1002/bies.201190016

Thomas DM; Conyers R; Young S, 2011, 'Liposarcoma: Molecular genetics and therapeutics', Sarcoma, 2011, http://dx.doi.org/10.1155/2011/483154

Newnham GM; Conron M; McLachlan SA; Dobrovic A; Do H; Li J; Opeskin K; Thompson N; Wright GM; Thomas DM, 2011, 'Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer', BMC Cancer, 11, http://dx.doi.org/10.1186/1471-2407-11-93

Aubin S; Barr R; Rogers P; Schacter B; Bielack SS; Ferrari A; Manchester RA; McMaster K; Morgan S; Patterson M; Petrilli AS; Ribera J-M; Shaw P; Thomas DM; Treadgold C, 2011, 'What Should the Age Range Be for AYA Oncology?', JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY, 1, pp. 3 - 10, http://dx.doi.org/10.1089/jayao.2011.1505

Ito M; Barys L; O'Reilly T; Young S; Gorbatcheva B; Monahan J; Zumstein-Mecker S; Choong PF; Dickinson I; Crowe P; Hemmings C; Desai J; Thomas DM; Lisztwan J, 2011, 'Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis', Clinical Cancer Research, 17, pp. 416 - 426, http://dx.doi.org/10.1158/1078-0432.CCR-10-2050

Neilsen PM; Pishas KI; Callen DF; Thomas DM, 2011, 'Targeting the p53 pathway in Ewing Sarcoma', Sarcoma, 2011, http://dx.doi.org/10.1155/2011/746939

Lockwood WW; Stack D; Morris T; Grehan D; O'Keane C; Stewart GL; Cumiskey J; Lam WL; Squire JA; Thomas DM; O'Sullivan MJ, 2011, 'Cyclin E1 is amplified and overexpressed in osteosarcoma', Journal of Molecular Diagnostics, 13, pp. 289 - 296, http://dx.doi.org/10.1016/j.jmoldx.2010.11.020

Collins IM; Thomas DM, 2011, 'Novel approaches to treatment of leiomyosarcomas', Current Oncology Reports, 13, pp. 316 - 322, http://dx.doi.org/10.1007/s11912-011-0173-0

Kuhn DM; Angoa-Perez M; Thomas DM, 2011, 'Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity', ILAR JOURNAL, 52, pp. 352 - 365, http://dx.doi.org/10.1093/ilar.52.3.352

Hemmings C; Miles C; Slavin J; Bonar SF; Graf N; Austen L; Thomas D; Desai J; Barry P, 2011, 'Optimising the management of soft tissue tumours', Pathology, 43, pp. 295 - 301, http://dx.doi.org/10.1097/PAT.0b013e3283464427

Roudier M; Blay* JY; Chawla S; Manivel C; Nelson SD; Thomas D; Woody L; Soriano R; Jun S; Jacobs I, 2011, 'Denosumab decreases proliferation in giant cell tumor of bone (GCTB)', Bone, 48, pp. S15 - S15, http://dx.doi.org/10.1016/j.bone.2010.10.039

Thomas DM; Albritton KH; Ferrari A, 2010, 'Adolescent and young adult oncology: An emerging field', Journal of Clinical Oncology, 28, pp. 4781 - 4782, http://dx.doi.org/10.1200/JCO.2010.30.5128

Ferrari A; Thomas D; Franklin ARK; Hayes-Lattin BM; Mascarin M; Van Der Graaf W; Albritton KH, 2010, 'Starting an Adolescent and Young Adult Program: Some success stories and some obstacles to overcome', Journal of Clinical Oncology, 28, pp. 4850 - 4857, http://dx.doi.org/10.1200/JCO.2009.23.8097

Thomas DM, 2010, 'Importance of molecular genetics of sarcomas', Cancer Forum, 34, pp. 154 - 156

Thomas D, 2010, 'The hard and soft sides of cancer programming', BioEssays, 32, pp. 837 - 838, http://dx.doi.org/10.1002/bies.201090036

Sargent DJ; Yothers GA; Green E; Blanke CD; O'Connell MJ; Labianca R; Bleyer A; De Gramont A; Thomas DM, 2010, 'Benefits and adverse events (AEs) in younger (Y) (age <50) versus older patients (pts) receiving adjuvant chemotherapy (AT) for colon cancer (CC): Findings from the 33,574 pt ACCENT dataset.', Journal of Clinical Oncology, 28, pp. 3523 - 3523, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.3523

Cassier PA; Stacchiotti S; Gelderblom H; Thomas DM; Van Der Graaf W; Seddon BM; Julien D; Wagner AJ; Blay J, 2010, 'Imatinib mesylate for the treatment of locally advanced and/or metastatic pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT).', Journal of Clinical Oncology, 28, pp. 10012 - 10012, http://dx.doi.org/10.1200/jco.2010.28.15_suppl.10012

Thomas D, 2010, 'Checkpoint Responses in Cancer Therapy', CANCER FORUM, 34, pp. 60 - 60, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000213401900015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomas D; Henshaw R; Skubitz K; Chawla S; Staddon A; Blay JY; Roudier M; Smith J; Ye Z; Sohn W; Dansey R; Jun S, 2010, 'Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study', The Lancet Oncology, 11, pp. 275 - 280, http://dx.doi.org/10.1016/S1470-2045(10)70010-3

Thomas D, 2010, 'MRI of Bone and Soft Tissue Sarcomas and Tumorlike Lesions', CANCER FORUM, 34, pp. 61 - 61, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000213401900018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Thomas D; Carriere P; Jacobs I, 2010, 'Safety of denosumab in giant-cell tumour of bone', The Lancet Oncology, 11, pp. 815, http://dx.doi.org/10.1016/S1470-2045(10)70170-4

Thomas DM; Wagner AJ, 2010, 'Specific targets in sarcoma and developmental therapeutics', JNCCN Journal of the National Comprehensive Cancer Network, 8, pp. 677 - 685, http://dx.doi.org/10.6004/jnccn.2010.0050

Thomas DM, 2010, 'Wnts, bone and cancer', Journal of Pathology, 220, pp. 1 - 4, http://dx.doi.org/10.1002/path.2635

Conyers R; Thomas D, 2010, 'Review of “Cancer – basic science and clinical aspects”', BioEssays, 32, pp. 914 - 916, http://dx.doi.org/10.1002/bies.201000084

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S31 - S31, http://dx.doi.org/10.1097/01268031-201042001-00063

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S12 - S12, http://dx.doi.org/10.1097/01268031-201042001-00014

Garsed DW; Holloway AJ; Thomas DM, 2009, 'Cancer-associated neochromosomes: A novel mechanism of oncogenesis', BioEssays, 31, pp. 1191 - 1200, http://dx.doi.org/10.1002/bies.200800208

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ (Cancer Research (2009) 69, (7473-7479))', Cancer Research, 69, pp. 8832, http://dx.doi.org/10.1158/0008-5472.CAN-09-3870

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ', Cancer Research, 69, pp. 7473 - 7479, http://dx.doi.org/10.1158/0008-5472.CAN-09-0194

Thomas DM; O'Sullivan B; Gronchi A, 2009, 'Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management', Expert Review of Anticancer Therapy, 9, pp. 1145 - 1157, http://dx.doi.org/10.1586/ERA.09.77

Khamly KK; Thursfield VJ; Fay M; Desai J; Toner GC; Choong PFM; Ngan SYK; Powell GJ; Thomas DM, 2009, 'Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood', International Journal of Cancer, 125, pp. 426 - 431, http://dx.doi.org/10.1002/ijc.24376

Thomas DM; Skubitz KM, 2009, 'Giant cell tumour of bone', Current Opinion in Oncology, 21, pp. 338 - 344, http://dx.doi.org/10.1097/CCO.0b013e32832c951d

Soliman H; Ferrari A; Thomas D, 2009, 'Sarcoma in the Young Adult Population: An International View', Seminars in Oncology, 36, pp. 227 - 236, http://dx.doi.org/10.1053/j.seminoncol.2009.03.006

Thomas DM; Chawla S; Skubitz K; Staddon A; Henshaw R; Blay J; Smith J; Ye Z; Roudier M; Jun S, 2009, 'Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study', Journal of Clinical Oncology, 27, pp. 10510 - 10510, http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10510

Kansara M; Tsang M; Kodjabachian L; Sims NA; Trivett MK; Ehrich M; Dobrovic A; Slavin J; Choong PFM; Simmons PJ; Dawid IB; Thomas DM, 2009, 'Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice', Journal of Clinical Investigation, 119, pp. 837 - 851, http://dx.doi.org/10.1172/JCI37175

Thomas D; Whyte S; Choong P, 2009, 'Australian Sarcona Study Group: Development and outlook', Cancer Forum, 33, pp. 25 - 28

Pires de Camargo V; van de Rijn M; de Alava E; Madoz-Gúrpide J; Pilotti S; von Mehren M; Pedeutour F; Maki RG; Rutkowski P; Thomas DM, 2009, 'Other Targetable Sarcomas', Seminars in Oncology, 36, pp. 358 - 371, http://dx.doi.org/10.1053/j.seminoncol.2009.06.008

Newnham GM; Thomas DM; McLachlan SA; Wright G; Conron M, 2008, 'Molecular Profiling of Non-Small Cell Lung Cancer: Of What Value in Clinical Practice?', Heart Lung and Circulation, 17, pp. 451 - 462, http://dx.doi.org/10.1016/j.hlc.2007.11.144

Gutierrez GM; Kong E; Sabbagh Y; Brown NE; Lee JS; Demay MB; Thomas DM; Hinds PW, 2008, 'Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1^-/- mice', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 18402 - 18407, http://dx.doi.org/10.1073/pnas.0805925105

Alvaro F; Young A; Goldstein D; Thomas D; McJannett M; Dillon R, 2008, 'Clinical oncological society of Australia: Adolescent and young adult cancer forum', Cancer Forum, 32, pp. 116 - 119

Thomas D; Chawla SP; Skubitz K; Staddon AP; Henshaw R; Blay JY; Smith J; Ye Z; Roudier M; Jun S, 2008, 'Denosumab treatment of giant cell tumor of bone: Interim analysis of an open-label phase II study', Journal of Clinical Oncology, 26, pp. 10500 - 10500, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.10500

Thomas DM; Francescutti-Verbeem DM; Kuhn DM, 2008, 'The newly synthesized pool of dopamine determines the severity of methamphetamine-induced neurotoxicity', JOURNAL OF NEUROCHEMISTRY, 105, pp. 605 - 616, http://dx.doi.org/10.1111/j.1471-4159.2007.05155.x

Bleyer A; Barr R; Hayes-Lattin B; Thomas D; Ellis C; Anderson B, 2008, 'The distinctive biology of cancer in adolescents and young adults', Nature Reviews Cancer, 8, pp. 288 - 298, http://dx.doi.org/10.1038/nrc2349

Khamly KK; Hicks RJ; McArthur GA; Thomas DM, 2008, 'The promise of PET in clinical management and as a sensitive test for drug cytotoxicity in sarcomas', Expert Review of Molecular Diagnostics, 8, pp. 105 - 119, http://dx.doi.org/10.1586/14737159.8.1.105

Clark JCM; Thomas DM; Choong PFM; Dass CR, 2007, 'RECK - A newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer', Cancer and Metastasis Reviews, 26, pp. 675 - 683, http://dx.doi.org/10.1007/s10555-007-9093-8

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