By Professor Emad El-Omar

Journal articles

Grant AM; Wileman SM; Ramsay CR; Mowat NA; Krukowski ZH; Heading RC; Thursz MR; Campbell MK; Mowat A; El-Omar E; Phull P; Sinclair T; Swan L; Clements B; Collins J; Kennedy A; Lawther H; Bennett D; Davies N; Toop S; Winwood P; Alderson D; Barham P; Green K; Mittal R; Asante M; El Hasani S; De Beaux A; Meekison L; Paterson-Brown S; Barkell H; Ferns G; Bailey M; Karanjia N; Rockall TA; Skelly L; Dakkak M; Royston C; Sedman P; Gordon K; Potts LF; Smith C; Zentler-Munro PL; Munro A; Dexter S; Moayeddi P; Lloyd DM; Loh V; Thursz M; Darzi A; Ahmed A; Greaves R; Sawyerr A; Wellwood J; Taylor T; Hosking S; Lowrey S; Snook J; Goggin P; Johns T; Quine A; Somers S; Toh S; Bancewicz J; Greenhalgh M; Rees W; Cheruvu CVN; Deakin M; Evans S; Green J; Leslie F; Baxter JN; Duane P; Rahman MM; Thomas M; Williams J; Maxton D; Sigurdsson A; Smith MSH; Townson G; Buckley C; Gore S; Kennedy RH; Khan ZH; Knight J; Alexander D; Miller G; Parker D; Turnbull A; Turvill J, 2009, 'Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial', BMJ (Online), 338, pp. 81 - 83, http://dx.doi.org/10.1136/bmj.a2664

Mbulaiteye SM; Hisada M; El-Omar EM, 2009, 'Helicobacter Pylori associated global gastric cancer burden', Frontiers in Bioscience, 14, pp. 1490 - 1504, http://dx.doi.org/10.2741/3320

Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'W1180 Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', Gastroenterology, 136, pp. A - 671, http://dx.doi.org/10.1016/s0016-5085(09)63093-6

Grant AM; Wileman SM; Ramsay CR; Mowat NA; Krukowski ZH; Heading RC; Thursz MR; Campbell MK; REFLUX Trial Group , 2008, 'Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial.', BMJ, 337, pp. a2664, http://dx.doi.org/10.1136/bmj.a2664

Mahajan R; El-Omar EM; Lissowska J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Sobin LH; Zatonski W; Channock SJ; Chow WH; Hou L, 2008, 'Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a polish population', Japanese Journal of Clinical Oncology, 38, pp. 626 - 633, http://dx.doi.org/10.1093/jjco/hyn075

Argent RH; Hale JL; El-Omar EM; Atherton JC, 2008, 'Differences in Helicobacter pylori CagA tyrosine phosphorylation motif patterns between western and East Asian strains, and influences on interleukin-8 secretion', Journal of Medical Microbiology, 57, pp. 1062 - 1067, http://dx.doi.org/10.1099/jmm.0.2008/001818-0

Grant A; Wileman S; Ramsay C; Boike L; Epstein D; Sculpher M; Macran S; Kilonzo M; Vale L; Francis J; Mowat A; Krukowski Z; Heading R; Thursz M; Russell I; Campbell M, 2008, 'The effectiveness and cost-effectiveness of minimal access surgery amongst people with gastro-oesophageal reflux disease - a UK collaborative study. The REFLUX trial', HEALTH TECHNOLOGY ASSESSMENT, 12, pp. 1 - +, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000267608400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McNamara D; El-Omar E, 2008, 'Helicobacter pylori infection and the pathogenesis of gastric cancer: A paradigm for host-bacterial interactions', Digestive and Liver Disease, 40, pp. 504 - 509, http://dx.doi.org/10.1016/j.dld.2008.02.031

McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2008, 'COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics', Histopathology, 52, pp. 806 - 815, http://dx.doi.org/10.1111/j.1365-2559.2008.03038.x

Snaith A; El-Omar EM, 2008, 'Helicobacter pylori: Host genetics and disease outcomes', Expert Review of Gastroenterology and Hepatology, 2, pp. 577 - 585, http://dx.doi.org/10.1586/17474124.2.4.577

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'A single nucleotide polymorphism in the TLR9 promoter (TLR9-1237T/C) increases the affinity of NF-kappa B protein binding and enhances transcriptional activity upon H-pylori infection', GASTROENTEROLOGY, 134, pp. A567 - A567, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'Role of chronic inflammation in sporadic colorectal neoplasia', GASTROENTEROLOGY, 134, pp. A293 - A294, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101502155&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Argent RH; Thomas RJ; Aviles-Jimenez F; Letley DP; Limb MC; El-Omar EM; Atherton JC, 2008, 'Toxigenic Helicobacter pylori infection precedes gastric hypochlorhydria in cancer relatives, and H. pylori virulence evolves in these families', Clinical Cancer Research, 14, pp. 2227 - 2235, http://dx.doi.org/10.1158/1078-0432.CCR-07-2022

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'Variable detection of entero-hepatic Helicobacter species in colonic mucosal pinch biopsies by different molecular techniques', GASTROENTEROLOGY, 134, pp. A655 - A655, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504599&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lochhead P; El-Omar EM, 2008, 'Gastric cancer', British Medical Bulletin, 85, pp. 87 - 100, http://dx.doi.org/10.1093/bmb/ldn007

Hold GL; El-Omar EM, 2008, 'Genetic aspects of inflammation and cancer', Biochemical Journal, 410, pp. 225 - 235, http://dx.doi.org/10.1042/BJ20071341

Amieva MR; El-Omar EM, 2008, 'Host-Bacterial Interactions in Helicobacter pylori Infection', Gastroenterology, 134, pp. 306 - 323, http://dx.doi.org/10.1053/j.gastro.2007.11.009

Rugge M; Correa P; Di Mario F; El-Omar E; Fiocca R; Geboes K; Genta RM; Graham DY; Hattori T; Malfertheiner P; Nakajima S; Sipponen P; Sung J; Weinstein W; Vieth M, 2008, 'OLGA staging for gastritis: A tutorial', Digestive and Liver Disease, 40, pp. 650 - 658, http://dx.doi.org/10.1016/j.dld.2008.02.030

El-Omar EM; Ng MT; Hold GL, 2008, 'Polymorphisms in Toll-like receptor genes and risk of cancer', Oncogene, 27, pp. 244 - 252, http://dx.doi.org/10.1038/sj.onc.1210912

McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'S1996 Role of Chronic Inflammation in Sporadic Colorectal Neoplasia', Gastroenterology, 134, http://dx.doi.org/10.1016/s0016-5085(08)61366-9

Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'T1807 A Single Nucleotide Polymorphism in the TLR9 Promoter (TLR9 −1237T/C) Increases the Affinity of NF-κB Protein Binding and Enhances Transcriptional Activity Upon H. pylori Infection', Gastroenterology, 134, pp. A - 567, http://dx.doi.org/10.1016/s0016-5085(08)62648-7

Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'W1208 Variable Detection of Entero-Hepatic Helicobacter Species in Colonic Mucosal Pinch Biopsies By Different Molecular Techniques', Gastroenterology, 134, pp. A - 655, http://dx.doi.org/10.1016/s0016-5085(08)63058-9

El-Omar EM, 2007, 'The clinician's guide to acid/peptic disorders and motility disorders of the gastrointestinal tract', Gut, 56, pp. 1487 - 1487, http://dx.doi.org/10.1136/gut.2007.121418

McNamara D; El-Omar EM, 2007, 'How accurate are fecal tests for determination of cure after Helicobacter pylori eradication therapy?: Commentary', Nature Clinical Practice Gastroenterology and Hepatology, 4, pp. 248 - 249, http://dx.doi.org/10.1038/ncpgasthep0790

Malfertheiner P; Megraud F; O'Morain CO; Bazzoli F; El-Omar E; Graham D; Hunt R; Rokkas T; Vakil N; Kuipers EJ, 2007, 'Current concepts in the management of helicobacter pylori infection - The maastricht III consensus report', Chinese Journal of Gastroenterology, 12, pp. 159

Lochhead P; El-Omar EM, 2007, 'Helicobacter pylori infection and gastric cancer', Best Practice and Research: Clinical Gastroenterology, 21, pp. 281 - 297, http://dx.doi.org/10.1016/j.bpg.2007.02.002

Ando T; Goto Y; Ishiguro K; Maeda O; Watanabe O; Ohmiya N; Niwa Y; Hamajima N; El-Omar E; Goto H, 2007, 'The interaction of host genetic factors and Helicobacter pylori infection', Inflammopharmacology, 15, pp. 10 - 14, http://dx.doi.org/10.1007/s10787-006-1556-y

Hold GL; Rabkin CS; Chow WH; Smith MG; Gammon MD; Risch HA; Vaughan TL; McColl KEL; Lissowska J; Zatonski W; Schoenberg JB; Blot WJ; Mowat NAG; Fraumeni JF; El-Omar EM, 2007, 'A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors', Gastroenterology, 132, pp. 905 - 912, http://dx.doi.org/10.1053/j.gastro.2006.12.026

Malfertheiner P; Mégraud F; O’Morain C; Bazzoli F; El-Omar E; Graham DY; Hunt R; Rokkas T; Vakil N; Kuipers EJ; Andersen L; Atherton J; Asaka M; Bytzer P; Chan F; Coelho LGV; De Wit N; Delchier JC; Di Mario F; Fock KM; Forman D; Fujioka T; Gasbarrini G; Genta R; Goh KL; Hirschl A; Hungin P; Isakov VA; Jones R; Kist M; Koletzko S; Kupcinskas L; Ladas S; Lanas A; Machado J; McColl KEL; Michetti P; Moayyedi P; Pilotto A; Quina M; Sharma P; Simsek Y; Sipponen P; Sollano J; Stockbrügger R; Sugano K; Vaira D; Vieth M; Xiao S, 2007, 'Current concepts in the management of helicobacter pylori infection: The maastricht III consensus report', Gut, 56, pp. 772 - 781, http://dx.doi.org/10.1136/gut.2006.101634

Hale JL; Argent RH; El-Omar EM; Atherton JC, 2007, 'Helicobacter pylori microevolution changing CagA tyrosine phosphorylation motif-C number affects the level of IL-8 release from gastric epithelial cells', ZOONOSES AND PUBLIC HEALTH, 54, pp. 90 - 91, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000250519200306&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hou L; El-Omar EM; Chen J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Chanock SJ; Zatonski W; Sobin LH; Lissowska J; Fraumeni JF; Chow WH, 2007, 'Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer', Carcinogenesis, 28, pp. 118 - 123, http://dx.doi.org/10.1093/carcin/bgl130

, 2007, '8th Advanced Medicine Symposium : Sultan Qaboos University, Sultanate of Oman5th - 8th March 2007', Sultan Qaboos University medical journal, 7, pp. 179 - 184

Hou L; El-Omar EM; Chen J; Grillo P; Rabkin CS; Baccarelli A; Yeager M; Chanock SJ; Zatonski W; Sobin LH; Lissowska J; Fraumeni JF; Chow WH, 2007, 'Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer', CARCINOGENESIS, 28, pp. 118 - 123, http://dx.doi.org/10.1093/carcin/bgl130

Derakhshan MH; El-Omar E; Oien K; Gillen D; Fyfe V; Crabtree JE; McColl KEL, 2006, 'Gastric histology, serological markers and age as predictors of gastric acid secretion in patients infected with Helicobacter pylori', Journal of Clinical Pathology, 59, pp. 1293 - 1299, http://dx.doi.org/10.1136/jcp.2005.036111

Baccarelli A; Hou L; Chen J; Lissowska J; El-Omar EM; Grillo P; Giacomini SM; Yaeger M; Bernig T; Zatonski W; Fraumeni JF; Chanock SJ; Chow WH, 2006, 'Mannose-binding lectin-2 genetic variation and stomach cancer risk', International Journal of Cancer, 119, pp. 1970 - 1975, http://dx.doi.org/10.1002/ijc.22075

Tseng FC; Brown EE; Maiese EM; Yeager M; Welch R; Gold BD; Owens M; Cranston B; Hanchard B; El-Omar E; Hisada M, 2006, 'Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children', Helicobacter, 11, pp. 425 - 430, http://dx.doi.org/10.1111/j.1523-5378.2006.00433.x

El-Omar EM, 2006, 'Role of host genes in sporadic gastric cancer', Best Practice and Research: Clinical Gastroenterology, 20, pp. 675 - 686, http://dx.doi.org/10.1016/j.bpg.2006.04.006

Smith MG; Hold GL; Tahara E; El-Omar EM, 2006, 'Cellular and molecular aspects of gastric cancer', World Journal of Gastroenterology, 12, pp. 2979 - 2990, http://dx.doi.org/10.3748/wjg.v12.i19.2979

McLeman L; McKinlay AW; El-Omar EM, 2006, 'GP management of dyspepsia', Practitioner, 250, pp. 134 - 146

El-Omar EM, 2006, 'What is the optimal therapy for the eradication of Helicobacter pylori? Commentary', Nature Clinical Practice Gastroenterology and Hepatology, 3, pp. 126 - 127, http://dx.doi.org/10.1038/ncpgasthep0422

Ando T; El-Omar EM; Goto Y; Nobata K; Watanabe O; Maeda O; Ishiguro K; Minami M; Hamajima N; Goto H, 2006, 'Interleukin 1B proinflammatory genotypes protect against gastro-oesophageal reflux disease through induction of corpus atrophy', Gut, 55, pp. 158 - 164, http://dx.doi.org/10.1136/gut.2005.072942

El-Omar EM, 2006, 'Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection', Gut, 55, pp. 144 - 146, http://dx.doi.org/10.1136/gut.2005.071779

Goto Y; Ando T; Yamamoto K; Tamakoshi A; El-Omar E; Goto H; Hamajima N, 2006, 'Association between serum pepsinogens and polymorphism of PTPN11 encoding SHP-2 among Helicobacter pylori seropositive Japanese', International Journal of Cancer, 118, pp. 203 - 208, http://dx.doi.org/10.1002/ijc.21338

Ando T; Minami M; Mizuno T; Watanabe O; Ishiguro K; Ina K; Kusugami K; Nobata K; Nishiwaki T; Tsuzuki T; Shimada M; El-Omar E; Goto H, 2005, 'Long-term follow-up after eradication of Helicobacter pylori with omeprazole, clarithromycin, and tinidazole (OCT regimen) in a Japanese population', Helicobacter, 10, pp. 379 - 384, http://dx.doi.org/10.1111/j.1523-5378.2005.00344.x

Macarthur M; Sharp L; Hold GL; Little J; El-Omar EM, 2005, 'The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the Northeast of Scotland', Cancer Epidemiology Biomarkers and Prevention, 14, pp. 1613 - 1618, http://dx.doi.org/10.1158/1055-9965.EPI-04-0878

Garza-González E; Bosques-Padilla FJ; El-Omar E; Hold G; Tijerina-Menchaca R; Maldonado-Garza HJ; Pérez-Pérez GI, 2005, 'Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico', International Journal of Cancer, 114, pp. 237 - 241, http://dx.doi.org/10.1002/ijc.20718

Hope ME; Hold GL; Kain R; El-Omar EM, 2005, 'Sporadic colorectal cancer - Role of the commensal microbiota', FEMS Microbiology Letters, 244, pp. 1 - 7, http://dx.doi.org/10.1016/j.femsle.2005.01.029

HOU L; ELOMAR E; GRILLO P; RABKIN C; BACCARELLI A; YEAGER M; CHANOCK S; ZATONSKI W; CHEN J; LISSOWSKA J, 2005, 'Polymorphisms in genes involved in Th1-type cell-mediated response and the risk of gastric cancer', Annals of Epidemiology, 15, pp. 660 - 660, http://dx.doi.org/10.1016/j.annepidem.2005.07.039

Ando T; Tsuzuki T; Mizuno T; Minami M; Ina K; Kusugami K; Takamatsu J; Adachi K; El-Omar E; Ohta M; Goto H, 2004, 'Characteristics of Helicobacter pylori-induced gastritis and the effect of H. pylori eradication in patients with chronic idiopathic thrombocytopenic purpura', Helicobacter, 9, pp. 443 - 452, http://dx.doi.org/10.1111/j.1083-4389.2004.00261.x

El-Omar EM, 2004, 'The role of interleukin-1 beta in Helicobacter pylori-associated disease', Netherlands Journal of Medicine, 62, pp. 47 - 52

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