Professor Gary David Housley

Professor Gary David Housley

Fields of research: Neurology and Neuromuscular Diseases, Animal Physiology - Cell, Central Nervous System, Peripheral Nervous System, Autonomic Nervous System
Campus: Kensington
Tags: Ageing and Older People, Expanding Knowledge in the Medical and Health Sciences

Research Interests: Director of the Translational Neuroscience Facility, School of Medical Sciences, UNSW Australia.   Research program is broadly within molecular, cellular and systems physiology in the nervous system, to establish new platforms for treatment of neurological disorders. The focus is on neuroprotection and repair processes, including synaptic plasticity with development and aging. A principal area of research concerns the molecular and cellular basis of hearing loss...

Research Interests: Director of the Translational Neuroscience Facility, School of Medical Sciences, UNSW Australia.   Research program is broadly within molecular, cellular and systems physiology in the nervous system, to establish new platforms for treatment of neurological disorders. The focus is on neuroprotection and repair processes, including synaptic plasticity with development and aging. A principal area of research concerns the molecular and cellular basis of hearing loss (auditory neuroscience), where we investigate cell signalling that contributes to sensory hair cell and neuronal death due to noise and aging. Study of neural development and synaptic plasticity in the auditory system informs on gene-targets for neural repair. This research has an applied arm with respect to bionics such as the cochlear implant, and more broadly in developing neural interfaces with the brain.  The reserach has led to development of an innovative gene delivery platform in combination with medical bionics.

Within the brain, we are investigating neural plasticity associated with driven input ( e.g. via the cochlear implant) and mechanisms for protection and repair of the nervous system (such as ischaemic brain injury, a model of stroke). Hearing loss is the most prominent sensory disability in our society. Stroke is the third highest killer and the most disabling for survivors. Our work is supported by national and international collaborations and funding.

Broad Research Areas:
Physiology, Neuroscience, ENT, Neurology, Neurodegenerative Diseases, Bionics,  Gene Therapy, Photonics,

Society Memberships & Professional Activities:
Assoc. Editor Positions:, - Autonomic Neuroscience Basic & Clinical (2010 - 2013), - Journal of the Association for Research in Otolaryngology (JARO)(2005 - 2007), , Guest Editor Positions:, - Purinergic Signalling(2010), , Editorial Boards:, - Purinergic Signalling (2004 - present), - Audiology & Neuro-Otology (1998 - present ), - Current Opinion in Central and Peripheral Nervous System Drugs (1998 - 2001), , Society Membership:, Australian Neuroscience Society, Australian Physiological Society, Society for Neuroscience (U.S.A, Association for Research in Otolaryngology (U.S.A.), Collegium Otorhinolarngologicium Amicitiae Sacrum (CORLAS)

Specific Research Keywords:
Brain Sciences, Neuroscience, Sensory Mechanisms, Stroke, Hearing, Gene Therapy, Bionics, Brain Injury.

Contact

+61 2 9385 1057

Videos

Bionic ear delivers DNA to regrow auditory nerve cells
Bionics-based gene delivery in the cochlea - a breakthrough from the Translational Neuroscience Facility to enhance to cochlear implant; Science Translational Medicine publication (Pinyon et al, 2014)

Research Activities

Link to Translational Neuroscience Facility

Link to Translational Neuroscience Facility

Translational Neuroscience Facility