By Professor Hongyuan (Robert) Yang

Journal articles

Kristiana I; Yang H; Brown AJ, 2008, 'Different kinetics of cholesterol delivery to components of the cholesterol homeostatic machinery: Implications for cholesterol trafficking to the endoplasmic reticulum', Biochimica et Biophysica ACTA - Molecular and Cell Biology of Lipids, 1781, pp. 724 - 730

Fei W; Shui G; Gaeta BA; Du XR; Kuerschner L; Liu P; Brown AJ; Wenk M; Parton R; Yang H, 2008, 'Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast', Journal of Cell Biology, 180, pp. 473 - 482, http://dx.doi.org/10.1083/icb.200711136

Fei W; Alfaro G; Muthusamy B; Klaassen Z; Graham T; Yang H; Beh C, 2008, 'Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae', Eukaryotic Cell, pp. 401 - 414

Low C; Yang H, 2008, 'Programmed cell death in fission yeast Schizosaccharomyces pombe', Biochimica et Biophysica ACTA - Molecular Cell Research, 1783, pp. 1335 - 1349

Toh SK; Gong J; Du GG; Li J; Yang S; Ye JM; Yao H; Zhang Y; Xue B; Li Q; Yang H; Wen Z; Li P, 2008, 'Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of Fsp27 deficient mice', PLoS One, 3, pp. 2890 - 2891

Chen X; Hu ZP; Yang XX; Huang M; Gao Y; Tang W; Chan SY; Dai X; Ye J; Ho PCL; Duan W; Yang HY; Zhu YZ; Zhou SF, 2006, 'Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer', International Immunopharmacology, 6, pp. 499 - 508, http://dx.doi.org/10.1016/j.intimp.2005.08.026

Zhang J; Huang M; Guan S; Bi HC; Pan Y; Duan W; Chan SY; Chen X; Hong YH; Bian JS; Yang H; Zhou S, 2006, 'A mechanistic study of the intestinal absorption of Cryptotanshinone, the major active constituent of Salvia miltiorrhiza', Journal of Pharmacology and Experimental Therapeutics, 317, pp. 1285 - 1294

Yang H, 2006, 'Nonvesicular sterol transport: two protein families and a sterol sensor?', Trends in Cell Biology, 16, pp. 427 - 432

Tian Q; Zhang J; Chan SY; Tan T; Duan W; Huang M; Zhu Y; Chan E; Yu Q; Nie YQ; Ho P; Li Q; Ng K; Yang H; Wei HE; Bian JS; Zhou S, 2006, 'Topotecan is a substrate for multidrug resistance associated protein 4', Current Drug Metabolism, 7, pp. 105 - 118

Low CP; Liew LP; Pervaiz S; Yang H, 2005, 'Apoptosis and lipoapoptosis in the fission yeast Schizosaccharomyces pombe', FEMS Yeast Research, 5, pp. 1199 - 1206, http://dx.doi.org/10.1016/j.femsyr.2005.07.004

Zhou S; Huang M; Xu A; Yang H; Duan W; Paxton JW, 2005, 'Prediction of herb-drug metabolic interactions: A simulation study', Phytotherapy Research, 19, pp. 464 - 471, http://dx.doi.org/10.1002/ptr.1559

Gao Y; Gao H; Chan E; Tang W; Xu A; Yang H; Huang M; Lan J; Li X; Duan W; Xu C; Zhou S, 2005, 'Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from ganoderma lucidum, in mice', Immunological Investigations, 34, pp. 171 - 198, http://dx.doi.org/10.1081/IMM-200055813

Wang P; Zhang Y; Li H; Chieu HK; Munn AL; Yang H, 2005, 'AAA ATPases regulate membrane association of yeast oxysterol binding proteins and cellular sterol metabolism', European Molecular Biology Organization, 24, pp. 2989 - 2999

He X; Lu Y; Saha N; Yang H; Heng CK, 2005, 'Acyl-CoA: Cholesterol acyltransferase-2 gene polymorphisms and their association with plasma lipids and coronary artery disease risks', Human Genetics, 118, pp. 393 - 403

Low C; Liew L; Pervaiz S; Yang H, 2005, 'Apoptosis and lipoapoptosis in yeast', Human Genetics, 5, pp. 1199 - 1206

Wang Q; Ting WL; Yang H; Wong PT, 2005, 'High doses of simavastatin upregulate dopamine D(1) and D(2) receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase', British Journal of Pharmacology, 144, pp. 933 - 939

Tian Q; Zhang J; Tan T; Chan E; Duan W; Chan S; Boelsterli UA; Ho P; Yang H; Bian JS; Huang M; Zhu Y; Xiong W; Li XR; Zhou S, 2005, 'Human multidrug resistance associated protein 4 confers resistance to camptothecins', Pharmaceutical Research, 22, pp. 1837 - 1853

Tian Q; Zhang J; Tan TMC; Chan E; Duan W; Chan SY; Boelsterli UA; Ho PC-L; Yang H; Bian J-S; Huang M; Zhu Y-Z; Xiong W; Li X; Zhou S, 2005, 'Human multidrug resistance associated protein 4 confers resistance to camptothecins.', Pharm Res, 22, pp. 1837 - 1853, http://dx.doi.org/10.1007/s11095-005-7595-z

Wang P; Duan W; Munn AL; Yang H, 2005, 'Molecular characterization of Oshop, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae', FEBS Journal, 272, pp. 4703 - 4715

Hu Z; Yang XQ; Ho P; Chan E; Chan S; Xu C; Li XR; Zhu YZ; Duan W; Chen X; Huang M; Yang H; Zhou S, 2005, 'St John`s Wort modulates the toxicities and pharmacokinetics of CPT-11 (irinotecan) in rats', Pharmaceutical Research, 22, pp. 902 - 914

Lim G; Zhu Y; Wang C; Tan B; Armstrong J; Dokland T; Yang H; Zhu YZ, 2005, 'The last five amino acid residues at the C-terminus of PRK1/PKN are essential for full lipid responsiveness', Cellular Signalling, 17, pp. 1084 - 1097

Armstrong JS; Whiteman M; Yang H; Jones DP; Sternberg P, 2004, 'Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells', Investigative Ophthalmology and Visual Science, 45, pp. 4183 - 4189, http://dx.doi.org/10.1167/iovs.04-0570

Zhang SP; Ren J; Zhang Q; Armstrong J; Munn AL; Yang H, 2004, 'Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells', Traffic (Malden), 5, pp. 1017 - 1030

Armstrong J; Yang H; Duan W; Whiteman M, 2004, 'Cytochrome bc1 regulates the mitochondrial permeability transition by two distinct pathways', The Journal of Biological Chemistry, 279, pp. 50420 - 50428

Kim K; Shin YK; Park J; Kim JH; Yang H; Han DM; Paik Y, 2004, 'Molecular cloning and biochemical characterization of Candida albicans acyl-CoA:sterol acyltransferase, a potential target of antifungal agents', Biochemical and Biophysical Research Communications, 2319, pp. 911 - 919

Zhang SP; Ren J; Zhang Q; Munn AL; Armstrong J; Yang H, 2004, 'Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport.', Traffic (Malden), 5, pp. 1017 - 1030

Armstrong J; Whiteman M; Yang H; Jones DP, 2004, 'The redox regulation of intermediary metabolism by a superoxide-acontase rheostat', BioEssays, 26, pp. 894 - 900

Tan JH; Low PS; Tan YS; Tong MC; Saha N; Yang H; Heng CK, 2003, 'ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore', Human Genetics, 113, pp. 106 - 117

Zhang Q; Chieu HK; Low C; Zhang SP; Heng CK; Yang H, 2003, 'Schizosaccharomyces pombe cells deficient in Triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase', The Journal of Biological Chemistry, 278, pp. 47145 - 47155

Woo WH; Yang H; Wong KP; Halliwell B, 2003, 'Sulphite oxidase gene expression in human brain and in other human and rat tissues', Biochemical and Biophysical Research Communications, 305, pp. 619 - 623

Yeo SC; Xu LL; Ren J; Boulton VJ; Wagle MD; Liu CF; Ren G; Wong P; Zahn DR; Sasajala P; Yang H; Piper RD; Munn AL, 2003, 'Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae', Journal of Cell Science, 116, pp. 3957 - 3970

Li T; Duan W; Yang H; Lee MK; Bte Mustafa F; Lee BH; Teo TS, 2001, 'Identification of two proteins, S14 and UIP1, that interact with UCH37', FEBS Letters, 488, pp. 201 - 205, http://dx.doi.org/10.1016/S0014-5793(00)02436-4

Li T; Naqvi NI; Yang H; Teo TS, 2000, 'Identification of a 26S proteasome-associated UCH in fission yeast', Biochemical and Biophysical Research Communications, 272, pp. 270 - 275, http://dx.doi.org/10.1006/bbrc.2000.2767

Liang JS; Wu X; Jiang H; Zhou M; Yang H; Angkeow P; Huang LS; Sturley SL; Ginsberg H, 1998, 'Translocation efficiency, susceptibility to proteasomal degradation, and lipid responsiveness of apolipoprotein B are determined by the presence of β sheet domains', Journal of Biological Chemistry, 273, pp. 35216 - 35221, http://dx.doi.org/10.1074/jbc.273.52.35216

Yang H; Cromley D; Wang H; Billheimer JT; Sturley SL, 1997, 'Functional expression of a cDNA to human acyl-coenzyme A:cholesterol acyltransferase in yeast. Species-dependent substrate specificity and inhibitor sensitivity', Journal of Biological Chemistry, 272, pp. 3980 - 3985, http://dx.doi.org/10.1074/jbc.272.7.3980

Arthington-Skaggs BA; Crowell DN; Yang H; Sturley SL; Bard M, 1996, 'Positive and negative regulation of a sterol biosynthetic gene (ERG3) in the post-squalene portion of the yeast ergosterol pathway', FEBS Letters, 392, pp. 161 - 165, http://dx.doi.org/10.1016/0014-5793(96)00807-1

Yang H; Bard M; Bruner DA; Gleeson A; Deckelbaum RJ; Aljinovic G; Pohl TM; Rothstein R; Sturley SL, 1996, 'Sterol esterification in yeast: A two-gene process', Science, 272, pp. 1353 - 1356, http://dx.doi.org/10.1126/science.272.5266.1353

Piper RC; Cooper AA; Yang H; Stevens TH, 1995, 'VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae', Journal of Cell Biology, 131, pp. 603 - 617, http://dx.doi.org/10.1083/jcb.131.3.603

Yan R; Qian H; Lukmantara I; Gao M; Du X; Yan N; Yang H, 'Human SEIPIN Binds Anionic Phospholipids', Dev. Cell, 47, pp. 248 - 256

Preprints

Wu J; Gao M; Wu X; Liu Y; Du X; Liang Y; Ma C; Li P; Chen F-J; Yang H, 2024, PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis, http://dx.doi.org/10.1101/2024.08.22.609036

Coates H; Olzomer E; Du X; Farrell R; Yang H; Byrne F; Brown A, 2022, Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase, http://dx.doi.org/10.1101/2022.08.18.504470

Amanda Tan RP; Kozlova I; Su F; Sah S; Keable R; Hagan W; Bustamante S; Du X; Osborne B; Turner N; Clemens K; Begg D; Phelps E; Yang H; Leshchyns’ka I; Sytnyk V, 2022, Neuronal growth regulator 1 (NEGR1) promotes synaptic targeting of glutamic acid decarboxylase 65 (GAD65), http://dx.doi.org/10.1101/2022.02.08.479601

Back to profile page