By Professor John Allan Eisman

Journal articles

Eisman JA; Geusens P; van den Bergh J, 2018, 'The Emperor's New Clothes: What Randomized Controlled Trials Don't Cover', Journal of Bone and Mineral Research, 33, pp. 1394 - 1396, http://dx.doi.org/10.1002/jbmr.3539

Shrosbree JE; Elder GJ; Eisman JA; Center JR, 2018, 'Acute hypocalcaemia following denosumab in heart and lung transplant patients with osteoporosis', Internal Medicine Journal, 48, pp. 681 - 687, http://dx.doi.org/10.1111/imj.13744

van Geel TACM; Bliuc D; Geusens PPM; Center JR; Dinant GJ; Tran T; van den Bergh JPW; McLellan AR; Eisman JA, 2018, 'Reduced mortality and subsequent fracture risk associated with oral bisphosphonate recommendation in a fracture liaison service setting: A prospective cohort study', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0198006

Chen W; Simpson JM; March LM; Blyth FM; Bliuc D; Tran T; Nguyen TV; Eisman JA; Center JR, 2018, 'Comorbidities Only Account for a Small Proportion of Excess Mortality After Fracture: A Record Linkage Study of Individual Fracture Types', Journal of Bone and Mineral Research, 33, pp. 795 - 802, http://dx.doi.org/10.1002/jbmr.3374

Alajlouni D; Bliuc D; Tran T; Pocock N; Nguyen TV; Eisman JA; Center JR, 2018, 'Nonstandard Lumbar Region in Predicting Fracture Risk', Journal of Clinical Densitometry, 21, pp. 220 - 226, http://dx.doi.org/10.1016/j.jocd.2017.05.014

Nguyen TV; Eisman JA, 2018, 'Assessment of Fracture Risk: Population Association Versus Individual Prediction', Journal of Bone and Mineral Research, 33, pp. 386 - 388, http://dx.doi.org/10.1002/jbmr.3367

Alonso N; Estrada K; Albagha OME; Herrera L; Reppe S; Olstad OK; Gautvik KM; Ryan NM; Evans KL; Nielson CM; Hsu YH; Kiel DP; Markozannes G; Ntzani EE; Evangelou E; Feenstra B; Liu X; Melbye M; Masi L; Brandi ML; Riches P; Daroszewska A; Olmos JM; Valero C; Castillo J; Riancho JA; Husted LB; Langdahl BL; Brown MA; Duncan EL; Kaptoge S; Khaw KT; Usategui-Martín R; Del Pino-Montes J; González-Sarmiento R; Lewis JR; Prince RL; D'Amelio P; Garciá-Giralt N; Nogués X; Mencej-Bedrac S; Marc J; Wolstein O; Eisman JA; Oei L; Medina-Gómez C; Schraut KE; Navarro P; Wilson JF; Davies G; Starr J; Deary I; Tanaka T; Ferrucci L; Gianfrancesco F; Gennari L; Lucas G; Elosua R; Uitterlinden AG; Rivadeneira F; Ralston SH, 2018, 'Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density', Annals of the Rheumatic Diseases, 77, pp. 378 - 385, http://dx.doi.org/10.1136/annrheumdis-2017-212469

Htet TD; Eisman JA; Elder GJ; Center JR, 2018, 'Worsening of soft tissue dystrophic calcification in an osteoporotic patient treated with teriparatide', Osteoporosis International, 29, pp. 517 - 518, http://dx.doi.org/10.1007/s00198-017-4330-7

Haifer C; Lucas RM; Clarke MW; Lawrance I; Hart PH; Center JR; Eisman JA; Ghaly S, 2018, 'P120 Vitamin D deficiency in Crohn’s disease', Journal of Crohn's and Colitis, 12, pp. S152 - S153, http://dx.doi.org/10.1093/ecco-jcc/jjx180.247

Trajanoska K; Morris JA; Oei L; Zheng HF; Evans DM; Kiel DP; Ohlsson C; Richards JB; Rivadeneira F; Forgett V; Leong A; Ahmad OS; Laurin C; Mokry LE; Ross S; Elks CE; Bowden J; Warrington NM; Kleinman A; Willems SM; Wright D; Day FR; Murray A; Ruth KS; Tsilidis KK; Ackert-Bicknell CL; Bassett JHD; van der Eerden BCJ; Gautvik K; Reppe S; Williams GR; Medina-Gómez C; Estrada K; Amin N; Bis JC; Breda S; Chasman ; Demissie S; Enneman AW; Hsu YH; Ingvarsson T; Kähönen M; Kammerer C; Lacroix AZ; Li G; Liu CT; Liu Y; Lorentzon M; Mägi R; Mihailov E; Mlani L; Moayyeri A; Nielson CM; Nerea A; Sham PC; Siggeirsdotir K; Sigurdsson G; Thorsteinsdottir U; Trompet S; Thorleifsson G; Vandenput L; van der Velde N; Viikari J; Xiao SM; Hua Zhao J; Akesson KE; Andersen M; Atanasovska B; Balcells S; Eriksson J; Formosa MM; Garcia-Ibarbia C; Gonzalez-Macias J; Garcia-Giralt N; Hallmans G; Karlsson M; Khusainova R; Kim ; Lee SH; Leung PC; Mallmin H; Kwok TCY; Masi L; Melin BS; Mencej-Bedrac S; Nethander M; Olmos JM; Kollia P; Prezelj J; Van Schoor ; Svensson O; Szulc P; Valero C; Woo J; Brandi M; Cheng S; Chapurlat R; Christiansen C; Cooper C; Dedoussis G, 2018, 'Assessment of the genetic and clinical determinants of fracture risk: Genome wide association and mendelian randomisation study', The BMJ, 362, http://dx.doi.org/10.1136/bmj.k3225

Sheu A; Lopes LBA; Eisman J; Center JR, 2017, 'Osteoporosis management in 2017: still thin and fragmented', Internal Medicine Journal, 47, pp. 1329 - 1330, http://dx.doi.org/10.1111/imj.13598

Tran T; Bliuc D; van Geel T; Adachi JD; Berger C; van den Bergh J; Eisman JA; Geusens P; Goltzman D; Hanley DA; Josse RG; Kaiser SM; Kovacs CS; Langsetmo L; Prior JC; Nguyen TV; Center JR, 2017, 'Population-Wide Impact of Non-Hip Non-Vertebral Fractures on Mortality', Journal of Bone and Mineral Research, 32, pp. 1802 - 1810, http://dx.doi.org/10.1002/jbmr.3118

Nguyen TV; Eisman JA, 2017, 'Fracture Risk Assessment: From Population to Individual', Journal of Clinical Densitometry, 20, pp. 368 - 378, http://dx.doi.org/10.1016/j.jocd.2017.06.023

Binkley N; Blank RD; Leslie WD; Lewiecki EM; Eisman JA; Bilezikian JP, 2017, 'Osteoporosis in Crisis: It's Time to Focus on Fracture', Journal of Bone and Mineral Research, 32, pp. 1391 - 1394, http://dx.doi.org/10.1002/jbmr.3182

Pham HM; Nguyen SC; Ho-Le TP; Center JR; Eisman JA; Nguyen TV, 2017, 'Association of Muscle Weakness With Post-Fracture Mortality in Older Men and Women: A 25-Year Prospective Study', Journal of Bone and Mineral Research, 32, pp. 698 - 707, http://dx.doi.org/10.1002/jbmr.3037

Ho-Le TP; Center JR; Eisman JA; Nguyen HT; Nguyen TV, 2017, 'Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling', Journal of Bone and Mineral Research, 32, pp. 285 - 293, http://dx.doi.org/10.1002/jbmr.2998

Pereira L; Bliuc D; Stanford P; Eisman JA; Center JR, 2017, 'More-than-minimal-trauma fractures are associated with low bone density: an 8-year prospective study', Osteoporosis International, 28, pp. 103 - 110, http://dx.doi.org/10.1007/s00198-016-3739-8

Lee P; Nair P; Eisman JA; Center JR, 2016, 'Bone Failure in Critical Illness', Critical Care Medicine, 44, pp. 2270 - 2274, http://dx.doi.org/10.1097/CCM.0000000000001874

Christoffersen T; Ahmed LA; Winther A; Nilsen OA; Furberg AS; Grimnes G; Dennison E; Center JR; Eisman JA; Emaus N, 2016, 'Fracture incidence rates in Norwegian children, The Tromsø Study, Fit Futures', Archives of Osteoporosis, 11, http://dx.doi.org/10.1007/s11657-016-0294-z

Eisman JA, 2016, '30th Anniversary Retrospective', Journal of Bone and Mineral Research, 31, pp. 1635, http://dx.doi.org/10.1002/jbmr.2865

Gulson B; Taylor A; Eisman J, 2016, 'Bone remodeling during pregnancy and post-partum assessed by metal lead levels and isotopic concentrations', Bone, 89, pp. 40 - 51, http://dx.doi.org/10.1016/j.bone.2016.05.005

Bliuc D; Tran T; Alarkawi D; Nguyen TV; Eisman JA; Center JR, 2016, 'Secular changes in postfracture outcomes over 2 decades in Australia: A time-trend comparison of excess postfracture mortality in two birth controls over two decades', Journal of Clinical Endocrinology and Metabolism, 101, pp. 2475 - 2483, http://dx.doi.org/10.1210/jc.2016-1514

Lee P; Ng C; Slattery A; Nair P; Eisman JA; Center JR, 2016, 'Preadmission bisphosphonate and mortality in critically ill patients', Journal of Clinical Endocrinology and Metabolism, 101, pp. 1945 - 1953, http://dx.doi.org/10.1210/jc.2015-3467

Alarkawi D; Bliuc D; Nguyen TV; Eisman JA; Center JR, 2016, 'Contribution of Lumbar Spine BMD to Fracture Risk in Individuals with T-Score Discordance', Journal of Bone and Mineral Research, 31, pp. 274 - 280, http://dx.doi.org/10.1002/jbmr.2611

Niu T; Liu N; Yu X; Zhao M; Choi HJ; Leo PJ; Brown MA; Zhang L; Pei YF; Shen H; He H; Fu X; Lu S; Chen XD; Tan LJ; Yang TL; Guo Y; Cho NH; Shen J; Guo YF; Nicholson GC; Prince RL; Eisman JA; Jones G; Sambrook PN; Tian Q; Zhu XZ; Papasian CJ; Duncan EL; Uitterlinden AG; Shin CS; Xiang S; Deng HW, 2016, 'Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies', Journal of Bone and Mineral Research, 31, pp. 358 - 368, http://dx.doi.org/10.1002/jbmr.2687

Styrkarsdottir U; Thorleifsson G; Gudjonsson SA; Sigurdsson A; Center JR; Lee SH; Nguyen TV; Kwok TCY; Lee JSW; Ho SC; Woo J; Leung PC; Kim BJ; Rafnar T; Kiemeney LA; Ingvarsson T; Koh JM; Tang NLS; Eisman JA; Christiansen C; Sigurdsson G; Thorsteinsdottir U; Stefansson K, 2016, 'Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms10129

Tan MZW; Ng JCF; Eisman JA; Ng DCE; Hansen L; Chandran M, 2016, 'A retrospective review of imaging and operative modalities performed in patients with primary hyperparathyroidism at a mid-volume surgical centre in Southeast Asia', Annals of the Academy of Medicine Singapore, 45, pp. 191 - 197

Pham HM; Nguyen ND; Center JR; Eisman JA; Nguyen TV, 2016, 'Contribution of Quadriceps Weakness to Fragility Fracture: A Prospective Study', Journal of Bone and Mineral Research, 31, pp. 208 - 214, http://dx.doi.org/10.1002/jbmr.2594

Robinson PC; Leo PJ; Pointon JJ; Harris J; Cremin K; Bradbury LA; Donnelly P; Barroso I; Blackwell JM; Bramon E; Brown MA; Casas JP; Corvin A; Deloukas P; Duncanson A; Jankowski J; Markus HS; Mathew CG; Palmer CNA; Plomin R; Rautanen A; Sawcer SJ; Trembath RC; Viswanathan AC; Wood NW; Spencer CCA; Band G; Bellenguez C; Freeman C; Hellenthal G; Giannoulatou E; Pirinen M; Pearson R; Strange A; Su Z; Vukcevic D; Langford C; Hunt SE; Edkins S; Gwilliam R; Blackburn H; Bumpstead SJ; Dronov S; Gillman M; Gray E; Hammond N; Jayakumar A; McCann OT; Liddle J; Potter SC; Ravindrarajah R; Ricketts M; Waller M; Weston P; Widaa S; Whittaker P; Mathew CG; Brown MA; McCloskey E; Eisman J; Jones G; Nicholson G; Eastell R; Sambrook P; Prince R; Dennison E; Reid I; Wark J; Stebbings S; Harrison AA; Evans DM; Duncan EL; Wordsworth BP, 2016, 'The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis', Genes and Immunity, 17, pp. 46 - 51, http://dx.doi.org/10.1038/gene.2015.49

Styrkarsdottir U; Thorleifsson G; Eiriksdottir B; Gudjonsson SA; Ingvarsson T; Center JR; Nguyen TV; Eisman JA; Christiansen C; Thorsteinsdottir U; Sigurdsson G; Stefansson K, 2016, 'Two Rare Mutations in the COL1A2 Gene Associate with Low Bone Mineral Density and Fractures in Iceland', Journal of Bone and Mineral Research, 31, pp. 173 - 179, http://dx.doi.org/10.1002/jbmr.2604

Omsland TK; Eisman JA; Næss Ø; Center JR; Gjesdal CG; Tell GS; Emaus N; Meyer HE; Søgaard AJ; Holvik K; Schei B; Forsmo S; Magnus JH, 2015, 'Educational Inequalities in Post-Hip Fracture Mortality: A NOREPOS Studys', Journal of Bone and Mineral Research, 30, pp. 2221 - 2228, http://dx.doi.org/10.1002/jbmr.2579

Reppe S; Wang Y; Thompson WK; McEvoy LK; Schork AJ; Zuber V; LeBlanc M; Bettella F; Mills IG; Desikan RS; Djurovic S; Gautvik KM; Dale AM; Andreassen OA; Estrada K; Styrkarsdottir U; Evangelou E; Hsu YH; Duncan EL; Ntzani EE; Oei L; Albagha OME; Amin N; Kemp JP; Koller DL; Li G; Liu CT; Minster RL; Moayyeri A; Vandenput L; Willner D; Xiao SM; Yerges-Armstrong LM; Zheng HF; Alonso N; Eriksson J; Kammerer CM; Kaptoge SK; Leo PJ; Thorleifsson G; Wilson SG; Wilson JF; Aalto V; Alen M; Aragaki AK; Aspelund T; Center JR; Dailiana Z; Duggan DJ; Garcia M; Garcia-Giralt N; Giroux S; Hallmans G; Hocking LJ; Husted LB; Jameson KA; Khusainova R; Kim GS; Kooperberg C; Koromila T; Kruk M; Laaksonen M; Lacroix AZ; Lee SH; Leung PC; Lewis JR; Masi L; Mencej-Bedrac S; Nguyen TV; Nogues X; Patel MS; Prezelj J; Rose LM; Scollen S; Siggeirsdottir K; Smith AV; Svensson O; Trompet S; Trummer O; Van Schoor NM; Woo J; Zhu K; Balcells S; Brandi ML; Buckley BM; Cheng S; Christiansen C; Cooper C; Dedoussis G; Ford I; Frost M; Goltzman D; González-Macías J; Kähönen M; Karlsson M; Khusnutdinova E; Koh JM; Kollia P; Langdahl BL; Leslie WD, 2015, 'Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0144531

Bone HG; Dempster DW; Eisman JA; Greenspan SL; McClung MR; Nakamura T; Papapoulos S; Shih WJ; Rybak-Feiglin A; Santora AC; Verbruggen N; Leung AT; Lombardi A, 2015, 'Erratum to: Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial (Osteoporosis International, 10.1007/s00198-014-2944-6)', Osteoporosis International, 26, pp. 2721, http://dx.doi.org/10.1007/s00198-015-3274-z

Zheng HF; Forgetta V; Hsu YH; Estrada K; Rosello-Diez A; Leo PJ; Dahia CL; Park-Min KH; Tobias JH; Kooperberg C; Kleinman A; Styrkarsdottir U; Liu CT; Uggla C; Evans DS; Nielson CM; Walter K; Pettersson-Kymmer U; McCarthy S; Eriksson J; Kwan T; Jhamai M; Trajanoska K; Memari Y; Min J; Huang J; Danecek P; Wilmot B; Li R; Chou WC; Mokry LE; Moayyeri A; Claussnitzer M; Cheng CH; Cheung W; Medina-Gómez C; Ge B; Chen SH; Choi K; Oei L; Fraser J; Kraaij R; Hibbs MA; Gregson CL; Paquette D; Hofman A; Wibom C; Tranah GJ; Marshall M; Gardiner BB; Cremin K; Auer P; Hsu L; Ring S; Tung JY; Thorleifsson G; Enneman AW; Van Schoor NM; De Groot LCPGM; Van Der Velde N; Melin B; Kemp JP; Christiansen C; Sayers A; Zhou Y; Calderari S; Van Rooij J; Carlson C; Peters U; Berlivet S; Dostie J; Uitterlinden AG; Williams SR; Farber C; Grinberg D; LaCroix AZ; Haessler J; Chasman DI; Giulianini F; Rose LM; Ridker PM; Eisman JA; Nguyen TV; Center JR; Nogues X; Garcia-Giralt N; Launer LL; Gudnason V; Mellström D; Vandenput L; Amin N; Van Duijn CM; Karlsson MK; Ljunggren Ö; Svensson O; Hallmans G; Rousseau F; Giroux S; Bussière J; Arp PP, 2015, 'Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture', Nature, 526, pp. 112 - 117, http://dx.doi.org/10.1038/nature14878

Bone HG; Dempster DW; Eisman JA; Greenspan SL; McClung MR; Nakamura T; Papapoulos S; Shih WJ; Rybak-Feiglin A; Santora AC; Verbruggen N; Leung AT; Lombardi A, 2015, 'Erratum to: Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial', Osteoporosis International, http://dx.doi.org/10.1007/s00198-015-3274-z

Tran TS; Center JR; Seibel MJ; Eisman JA; Kushnir MM; Rockwood AL; Nguyen TV, 2015, 'Relationship between serum testosterone and fracture risk in men: A comparison of RIA and LC-MS/MS', Clinical Chemistry, 61, pp. 1182 - 1190, http://dx.doi.org/10.1373/clinchem.2015.242339

Tangvik RJ; Tell GS; Guttormsen AB; Eisman JA; Henriksen A; Nilsen RM; Ranhoff AH, 2015, 'Nutritional risk profile in a university hospital population', Clinical Nutrition, 34, pp. 705 - 711, http://dx.doi.org/10.1016/j.clnu.2014.08.001

Yang S; Center JR; Eisman JA; Nguyen TV, 2015, 'Erratum to: Association between fat mass, lean mass, and bone loss: the Dubbo osteoporosis epidemiology study, (Osteoporosis International, 10.1007/s00198-014-3009-6)', Osteoporosis International, 26, pp. 1865 - 1866, http://dx.doi.org/10.1007/s00198-015-3101-6

Horowitz M; Morris H; Need A; Seeman E; Prince R; Eisman J; Seibel M; Gallagher JC, 2015, 'In Memoriam: B E Christopher Nordin', JOURNAL OF BONE AND MINERAL RESEARCH, 30, pp. 949 - 950, http://dx.doi.org/10.1002/jbmr.2505

Kon E; Filardo G; Shani J; Altschuler N; Levy A; Zaslav K; Eisman JE; Robinson D, 2015, 'Osteochondral regeneration with a novel aragonite-hyaluronate biphasic scaffold: Up to 12-month follow-up study in a goat model', Journal of Orthopaedic Surgery and Research, 10, http://dx.doi.org/10.1186/s13018-015-0211-y

Niu T; Liu N; Zhao M; Xie G; Zhang L; Li J; Pei YF; Shen H; Fu X; He H; Lu S; Chen XD; Tan LJ; Yang TL; Guo Y; Leo PJ; Duncan EL; Shen J; Guo YF; Nicholson GC; Prince RL; Eisman JA; Jones G; Sambrook PN; Hu X; Das PM; Tian Q; Zhu XZ; Papasian CJ; Brown MA; Uitterlinden AG; Wang YP; Xiang S; Deng HW, 2015, 'Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies', Human Molecular Genetics, 24, pp. 4710 - 4727, http://dx.doi.org/10.1093/hmg/ddv144

Bliuc D; Nguyen ND; Alarkawi D; Nguyen TV; Eisman JA; Center JR, 2015, 'Accelerated bone loss and increased post-fracture mortality in elderly women and men', Osteoporosis International, 26, pp. 1331 - 1339, http://dx.doi.org/10.1007/s00198-014-3014-9

Yang S; Center JR; Eisman JA; Nguyen TV, 2015, 'Association between fat mass, lean mass, and bone loss: the Dubbo osteoporosis epidemiology study', Osteoporosis International, 26, pp. 1381 - 1386, http://dx.doi.org/10.1007/s00198-014-3009-6

Bliuc D; Alarkawi D; Nguyen TV; Eisman JA; Center JR, 2015, 'Risk of subsequent fractures and mortality in elderly women and men with fragility fractures with and without osteoporotic bone density: The dubbo osteoporosis epidemiology study', Journal of Bone and Mineral Research, 30, pp. 637 - 646, http://dx.doi.org/10.1002/jbmr.2393

Søgaard AJ; Holvik K; Omsland TK; Tell GS; Dahl C; Schei B; Falch JA; Eisman JA; Meyer HE, 2015, 'Abdominal obesity increases the risk of hip fracture. A population-based study of 43 000 women and men aged 60-79 years followed for 8 years. Cohort of Norway', Journal of Internal Medicine, 277, pp. 306 - 317, http://dx.doi.org/10.1111/joim.12230

Bone HG; Dempster DW; Eisman JA; Greenspan SL; McClung MR; Nakamura T; Papapoulos S; Shih WJ; Rybak-Feiglin A; Santora AC; Verbruggen N; Leung AT; Lombardi A, 2015, 'Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial', Osteoporosis International, 26, pp. 699 - 712, http://dx.doi.org/10.1007/s00198-014-2944-6

Brzozowska MM; Sainsbury A; Eisman JA; Baldock PA; Center JR, 2014, 'Bariatric Surgery and Bone Loss: Do We Need to Be Concerned?', Clinical Reviews in Bone and Mineral Metabolism, 12, pp. 207 - 227, http://dx.doi.org/10.1007/s12018-014-9162-9

Selecki Y; Eisman JA, 2014, 'Osteoporosis and fragility fractures A practical approach', Medicine Today, 15, pp. 18 - 27

Chan MY; Frost SA; Center JR; Eisman JA; Nguyen TV, 2014, 'Relationship between body mass index and fracture risk is mediated by bone mineral density', Journal of Bone and Mineral Research, 29, pp. 2327 - 2335, http://dx.doi.org/10.1002/jbmr.2288

Johansson H; Kanis JA; Odén A; Leslie WD; Fujiwara S; Glüer CC; Kroger H; LaCroix AZ; Lau E; Melton LJ; Eisman JA; O’Neill TW; Goltzman D; Reid DM; McCloskey E, 2014, 'Impact of Femoral Neck and Lumbar Spine BMD Discordances on FRAX Probabilities in Women: A Meta-analysis of International Cohorts', Calcified Tissue International, 95, pp. 428 - 435, http://dx.doi.org/10.1007/s00223-014-9911-2

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