By Professor Kate Louise Seib

Journal articles

Blakeway LV; Tan A; Peak IR; Atack JM; Seib KL, 2020, 'Proteome of a Moraxella catarrhalis Strain under Iron-Restricted Conditions', Microbiology Resource Announcements, 9, http://dx.doi.org/10.1128/MRA.00064-20

Blakeway LV; Tan A; Jurcisek JA; Bakaletz LO; Atack JM; Peak IR; Seib KL, 2019, 'The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media', BMC Microbiology, 19, http://dx.doi.org/10.1186/s12866-019-1660-y

Tan A; Li WS; Verderosa AD; Blakeway LV; D. Mubaiwa T; Totsika M; Seib KL, 2019, 'Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-39374-0

Atack JM; Murphy TF; Pettigrew MM; Seib KL; Jennings MP, 2019, 'Non-typeable Haemophilus influenzae isolates from patients with chronic obstructive pulmonary disease contain new phase-variable modA methyltransferase alleles controlling phasevarions', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-52429-6

Seib KL; Haag AF; Oriente F; Fantappiè L; Borghi S; Semchenko EA; Schulz BL; Ferlicca F; Taddei AR; Giuliani MM; Pizza M; Delany I, 2019, 'The meningococcal vaccine antigen GNA2091 is an analogue of YraP and plays key roles in outer membrane stability and virulence', FASEB Journal, 33, pp. 12324 - 12335, http://dx.doi.org/10.1096/fj.201900669R

Semchenko EA; Tan A; Borrow R; Seib KL, 2019, 'The Serogroup B Meningococcal Vaccine Bexsero Elicits Antibodies to Neisseria gonorrhoeae', Clinical Infectious Diseases, 69, pp. 1101 - 1111, http://dx.doi.org/10.1093/cid/ciy1061

Phillips ZN; Tram G; Seib KL; Atack JM, 2019, 'Phase-variable bacterial loci: How bacteria gamble to maximise fitness in changing environments', Biochemical Society Transactions, 47, pp. 1131 - 1141, http://dx.doi.org/10.1042/BST20180633

Atack JM; Murphy TF; Pettigrew MM; Seib KL; Jennings MP, 2019, 'Transcriptome sequencing data sets for determining gene expression changes mediated by phase-variable DNA methyltransferases in nontypeable haemophilus influenzae strains isolated from patients with chronic obstructive pulmonary disease', Microbiology Resource Announcements, 8, http://dx.doi.org/10.1128/MRA.00526-19

Semchenko EA; Everest-Dass AV; Jen FEC; Mubaiwa TD; Day CJ; Seib KL, 2019, 'Glycointeractome of neisseria gonorrhoeae: Identification of host glycans targeted by the gonococcus to facilitate adherence to cervical and urethral epithelial cells', Mbio, 10, http://dx.doi.org/10.1128/mBio.01339-19

Day CJ; Hartley-Tassell LE; Seib KL; Tiralongo J; Bovin N; Savino S; Masignani V; Jennings MP, 2019, 'Lectin activity of Pseudomonas aeruginosa vaccine candidates PSE17-1, PSE41-5 and PSE54', Biochemical and Biophysical Research Communications, 513, pp. 287 - 290, http://dx.doi.org/10.1016/j.bbrc.2019.03.092

Phillips ZN; Brizuela C; Jennison AV; Staples M; Grimwood K; Seib KL; Jennings MP; Atack JM, 2019, 'Analysis of invasive nontypeable Haemophilus influenzae isolates reveals selection for the expression state of particular phase-variable lipooligosaccharide biosynthetic genes', Infection and Immunity, 87, http://dx.doi.org/10.1128/IAI.00093-19

Jayasundara P; Regan DG; Seib KL; Jayasundara D; Wood JG, 2019, 'Modelling the in-host dynamics of Neisseria gonorrhoeae infection', Pathogens and Disease, 77, http://dx.doi.org/10.1093/femspd/ftz008

Hartley-Tassell LE; Awad MM; Seib KL; Scarselli M; Savino S; Tiralongo J; Lyras D; Day CJ; Jennings MP, 2019, 'Lectin activity of the TcdA and TcdB toxins of Clostridium difficile', Infection and Immunity, 87, http://dx.doi.org/10.1128/IAI.00676-18

Palmu AA; Ware RS; Lambert SB; Sarna M; Bialasiewicz S; Seib KL; Atack JM; Nissen MD; Grimwood K, 2019, 'Nasal swab bacteriology by PCR during the first 24-months of life: A prospective birth cohort study', Pediatric Pulmonology, 54, pp. 289 - 296, http://dx.doi.org/10.1002/ppul.24231

Hare KM; Seib KL; Chang AB; Harris TM; Spargo JC; Smith-Vaughan HC, 2019, 'Antimicrobial susceptibility and impact of macrolide antibiotics on moraxella catarrhalis in the upper and lower airways of children with chronic endobronchial suppuration', Journal of Medical Microbiology, 68, pp. 1140 - 1147, http://dx.doi.org/10.1099/jmm.0.001033

Brown P; Zhou Y; Tan AC; El-Esawi MA; Liehr T; Blanck O; Gladue DP; Almeida GMF; Cernava T; Sorzano CO; Yeung AWK; Engel MS; Chandrasekaran AR; Muth T; Staege MS; Daulatabad SV; Widera D; Zhang J; Meule A; Honjo K; Pourret O; Yin CC; Zhang Z; Cascella M; Flegel WA; Goodyear CS; van Raaij MJ; Bukowy-Bieryllo Z; Campana LG; Kurniawan NA; Lalaouna D; Hüttner FJ; Ammerman BA; Ehret F; Cobine PA; Tan EC; Han H; Xia W; McCrum C; Dings RPM; Marinello F; Nilsson H; Nixon B; Voskarides K; Yang L; Costa VD; Bengtsson-Palme J; Bradshaw W; Grimm DG; Kumar N; Martis E; Prieto D; Sabnis SC; Amer SEDR; Liew AWC; Perco P; Rahimi F; Riva G; Zhang C; Devkota HP; Ogami K; Basharat Z; Fierz W; Siebers R; Tan KH; Boehme KA; Brenneisen P; Brown JAL; Dalrymple BP; Harvey DJ; Ng G; Werten S; Bleackley M; Dai Z; Dhariwal R; Gelfer Y; Hartmann MD; Miotla P; Tamaian R; Govender P; Gurney-Champion OJ; Kauppila JH; Zhang X; Echeverría N; Subhash S; Sallmon H; Tofani M; Bae T; Bosch O; Cuív PO; Danchin A; Diouf B; Eerola T; Evangelou E; Filipp F; Klump H; Kurgan L; Smith SS; Terrier O; Tuttle N; Kohonen-Corish M; Lovell N; Webster R; Nakagawa-Lagisz M; Tahir N; Rouet R; Sharma S; Seib KL; Litfin T, 2019, 'Large expert-curated database for benchmarking document similarity detection in biomedical literature search', Database, 2019, pp. 1 - 67, http://dx.doi.org/10.1093/database/baz085

Phillips ZN; Husna AU; Jennings MP; Seib KL; Atack JM, 2019, 'Phasevarions of bacterial pathogens-phase-variable epigenetic regulators evolving from restriction-modification systems', Microbiology United Kingdom, 165, pp. 917 - 928, http://dx.doi.org/10.1099/mic.0.000805

Seib KL; Peak IR, 2019, 'Preface', Methods in Molecular Biology, 1969, pp. v - vii

Jen FEC; Seib KL; Tan A, 2019, 'Screening DNA repeat tracts of phase variable genes by fragment analysis', , 1969, pp. 93 - 104, http://dx.doi.org/10.1007/978-1-4939-9202-7_6

Zhan J; Jia H; Semchenko EA; Bian Y; Zhou AM; Li Z; Yang Y; Wang J; Sarkar S; Totsika M; Blanchard H; Jen FEC; Ye Q; Haselhorst T; Jennings MP; Seib KL; Zhou Y, 2019, 'Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: A new strategy to generate antimicrobial peptides', FASEB Journal, 33, pp. 2095 - 2104, http://dx.doi.org/10.1096/fj.201700613RR

Jen FEC; Semchenko EA; Day CJ; Seib KL; Jennings MP, 2019, 'The Neisseria gonorrhoeae methionine sulfoxide reductase (MsrA/B) is a surface exposed, immunogenic, vaccine candidate', Frontiers in Immunology, 10, http://dx.doi.org/10.3389/fimmu.2019.00137

Mubaiwa TD; Hartley-Tassell LE; Semchenko EA; Day CJ; Jennings MP; Seib KL, 2018, 'The Bexsero Neisseria meningitidis serogroup B vaccine antigen NHBA is a high-affinity chondroitin sulfate binding protein', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-24639-x

Seib K, 2018, 'Report from ASM 2018', Microbiology Australia, 39, pp. 173 - 175, http://dx.doi.org/10.1071/ma18051

Atack JM; Tan A; Bakaletz LO; Jennings MP; Seib KL, 2018, 'Phasevarions of Bacterial Pathogens: Methylomics Sheds New Light on Old Enemies', Trends in Microbiology, 26, pp. 715 - 726, http://dx.doi.org/10.1016/j.tim.2018.01.008

Atack JM; Murphy TF; Bakaletz LO; Seib KL; Jennings MP, 2018, 'Closed complete genome sequences of two nontypeable haemophilus influenzae strains containing novel modA alleles from the sputum of patients with chronic obstructive pulmonary disease', Microbiology Resource Announcements, 7, http://dx.doi.org/10.1128/MRA.00821-18

Edwards JL; Jennings MP; Seib KL, 2018, 'Neisseria gonorrhoeae vaccine development: Hope on the horizon?', Current Opinion in Infectious Diseases, 31, pp. 246 - 250, http://dx.doi.org/10.1097/QCO.0000000000000450

Atack JM; Yang Y; Seib KL; Zhou Y; Jennings MP, 2018, 'A survey of Type III restriction-modification systems reveals numerous, novel epigenetic regulators controlling phase-variable regulons; phasevarions', Nucleic Acids Research, 46, pp. 3532 - 3542, http://dx.doi.org/10.1093/NAR/GKY192

Seib KL; Jennings MP; Day CJ, 2018, 'Characterizing the meningococcal glycointeractome: What is new?', Future Microbiology, 13, pp. 279 - 282, http://dx.doi.org/10.2217/fmb-2017-0222

Blakeway LV; Tan A; Lappan R; Ariff A; Pickering JL; Peacock CS; Blyth CC; Kahler CM; Chang BJ; Lehmann D; Kirkham LAS; Murphy TF; Jennings MP; Bakaletz LO; Atack JM; Peak IR; Seib KL, 2018, 'Moraxella catarrhalis Restriction–Modification Systems Are Associated with Phylogenetic Lineage and Disease', Genome Biology and Evolution, 10, pp. 2932 - 2946, http://dx.doi.org/10.1093/gbe/evy226

Day CJ; Paton AW; Harvey RM; Hartley-Tassell LE; Seib KL; Tiralongo J; Bovin N; Savino S; Masignani V; Paton JC; Jennings MP, 2017, 'Lectin activity of the pneumococcal pilin proteins', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-17850-9

Mubaiwa TD; Hartley-Tassell LE; Semchenko EA; Jen FEC; Srikhanta YN; Day CJ; Jennings MP; Seib KL, 2017, 'The glycointeractome of serogroup B Neisseria meningitidis strain MC58', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-05894-w

Blakeway LV; Tan A; Peak IRA; Seib KL, 2017, 'Virulence determinants of moraxella catarrhalis: Distribution and considerations for vaccine development', Microbiology United Kingdom, 163, pp. 1371 - 1384, http://dx.doi.org/10.1099/mic.0.000523

Seib KL, 2017, 'Gonorrhoea vaccines: a step in the right direction', Lancet, 390, pp. 1567 - 1569, http://dx.doi.org/10.1016/S0140-6736(17)31605-7

Seib KL; Jen FEC; Scott AL; Tan A; Jennings MP, 2017, 'Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria', Pathogens and Disease, 75, http://dx.doi.org/10.1093/femspd/ftx080

Mubaiwa TD; Semchenko EA; Hartley-Tassell LE; Day CJ; Jennings MP; Seib KL, 2017, 'The sweet side of the pathogenic Neisseria: The role of glycan interactions in colonisation and disease', Pathogens and Disease, 75, http://dx.doi.org/10.1093/femspd/ftx063

Tan A; Blakeway LV; Bakaletz LO; Boitano M; Clark TA; Korlach J; Jennings MP; Peak IR; Seib KL, 2017, 'Complete genome sequence of Moraxella catarrhalis strain CCRI- 195ME, isolated from the middle ear', Genome Announcements, 5, http://dx.doi.org/10.1128/genomeA.00384-17

Semchenko EA; Day CJ; Seib KL, 2017, 'MetQ of Neisseria gonorrhoeae is a surfaceexpressed antigen that elicits bactericidal and functional blocking antibodies', Infection and Immunity, 85, http://dx.doi.org/10.1128/IAI.00898-16

Semchenko EA; Seib KL, 2016, 'Intractable problems require novel solutions: It's time to get serious about developing a gonorrhoea vaccine', Sexually Transmitted Infections, 92, pp. 561 - 562, http://dx.doi.org/10.1136/sextrans-2015-052378

Edwards JL; Jennings MP; Apicella MA; Seib KL, 2016, 'Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development', Critical Reviews in Microbiology, 42, pp. 928 - 941, http://dx.doi.org/10.3109/1040841X.2015.1105782

Vacca I; Del Tordello E; Gasperini G; Pezzicoli A; Di Fede M; Paccani SR; Marchi S; Mubaiwa TD; Hartley-Tassell LE; Jennings MP; Seib KL; Masignani V; Pizza M; Serruto D; Aricò B; Delany I, 2016, 'Neisserial heparin binding antigen (NHBA) contributes to the adhesion of Neisseria meningitidis to human epithelial cells', Plos One, 11, http://dx.doi.org/10.1371/journal.pone.0162878

Tan A; Hill DMC; Harrison OB; Srikhanta YN; Jennings MP; Maiden MCJ; Seib KL, 2016, 'Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: Implications for gene regulation and virulence', Scientific Reports, 6, http://dx.doi.org/10.1038/srep21015

Tan A; Atack JM; Jennings MP; Seib KL, 2016, 'The capricious nature of bacterial pathogens: Phasevarions and vaccine development', Frontiers in Immunology, 7, http://dx.doi.org/10.3389/fimmu.2016.00586

Craig AP; Gray RT; Edwards JL; Apicella MA; Jennings MP; Wilson DP; Seib KL, 2015, 'The potential impact of vaccination on the prevalence of gonorrhea', Vaccine, 33, pp. 4520 - 4525, http://dx.doi.org/10.1016/j.vaccine.2015.07.015

Seib KL; Scarselli M; Comanducci M; Toneatto D; Masignani V, 2015, 'Neisseria meningitidis factor H-binding protein fHbp: Key virulence factor and vaccine antigen', Expert Review of Vaccines, 14, pp. 841 - 859, http://dx.doi.org/10.1586/14760584.2015.1016915

Seib KL; Jen FEC; Tan A; Scott AL; Kumar R; Power PM; Chen LT; Wu HJ; Wang AHJ; Hill DMC; Luyten YA; Morgan RD; Roberts RJ; Maiden MCJ; Boitano M; Clark TA; Korlach J; Rao DN; Jennings MP, 2015, 'Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N6-adenine DNA methyltransferases of Neisseria meningitidis', Nucleic Acids Research, 43, pp. 4150 - 4162, http://dx.doi.org/10.1093/nar/gkv219

Newton HJ; Seib KL, 2015, 'Science meets Parliament 2015', MICROBIOLOGY AUSTRALIA, 36, pp. 140 - +, http://dx.doi.org/10.1071/MA15048

Blakeway LV; Power PM; Jen FEC; Worboys SR; Boitano M; Clark TA; Korlach J; Bakaletz LO; Jennings MP; Peak IR; Seib KL, 2014, 'ModM DNA methyltransferase methylome analysis reveals a potential role for Moraxella catarrhalis phasevarions in otitis media', FASEB Journal, 28, pp. 5197 - 5207, http://dx.doi.org/10.1096/fj.14-256578

Jen FEC; Seib KL; Jennings MP, 2014, 'Phasevarions mediate epigenetic regulation of antimicrobial susceptibility in Neisseria meningitidis', Antimicrobial Agents and Chemotherapy, 58, pp. 4219 - 4221, http://dx.doi.org/10.1128/AAC.00004-14

Nesta B; Valeri M; Spagnuolo A; Rosini R; Mora M; Donato P; Alteri CJ; Del Vecchio M; Buccato S; Pezzicoli A; Bertoldi I; Buzzigoli L; Tuscano G; Falduto M; Rippa V; Ashhab Y; Bensi G; Fontana MR; Seib KL; Mobley HLT; Pizza M; Soriani M; Serino L, 2014, 'SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains', Plos Pathogens, 10, http://dx.doi.org/10.1371/journal.ppat.1004124

Delany I; Rappuoli R; Seib KL, 2013, 'Vaccines, reverse vaccinology, and bacterial pathogenesis', Cold Spring Harbor Perspectives in Medicine, 3, http://dx.doi.org/10.1101/cshperspect.a012476

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