By Professor Kerry-Anne Rye

Journal articles

Tso C; Rye K; Barter P, 2013, 'Effects of Low-Density Lipoproteins on Endothelium-Generation from Human Peripheral Blood Mononuclear Cells', Heart, Lung and Circulation, 22, pp. S16 - S16, http://dx.doi.org/10.1016/j.hlc.2013.05.034

Bisoendial R; Roediger B; Jain R; Cavanagh L; Tak P-P; Rye K-A; Weninger W, 2013, 'THU0096 Targeting Lymphatic Dysfunction in Rheumatoid Arthritis by High-Density Lipoprotein', Annals of the Rheumatic Diseases, 72, pp. A195.2 - A195, http://dx.doi.org/10.1136/annrheumdis-2013-eular.624

Ong KL; Rye KA; O'Connell R; Jenkins AJ; Brown C; Xu A; Sullivan DR; Barter PJ; Keech AC, 2012, 'Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes', Journal of Clinical Endocrinology and Metabolism, 97, pp. 4701 - 4708, http://dx.doi.org/10.1210/jc.2012-2267

Barter PJ; Rye KA; Beltangady MS; Ports WC; Duggan WT; Boekholdt SM; DeMicco DA; Kastelein JJP; Shear CL, 2012, 'Relationship between atorvastatin dose and the harm caused by torcetrapib', Journal of Lipid Research, 53, pp. 2436 - 2442, http://dx.doi.org/10.1194/jlr.P026328

Barter PJ; Rye KA, 2012, 'Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk', Journal of Lipid Research, 53, pp. 1755 - 1766, http://dx.doi.org/10.1194/jlr.R024075

Ismael F; Hadfield KA; Pattison DI; Rye KA; Davies MJ; Hawkins CL, 2012, 'Role of lipoprotein modification by the myeloperoxidase-derived oxidant HOSCN in the formation of foam cells in atherosclerosis', FREE RADICAL BIOLOGY AND MEDICINE, 53, pp. S130 - S131, http://dx.doi.org/10.1016/j.freeradbiomed.2012.08.273

Borthwick F; Warnakula S; Mangat R; Uwiera RR; Russell JC; Kelly SE; Lee CY; Hryshko L; Mamo JCL; Rye KA; Lopaschuk GD; Proctor SD, 2012, 'ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance', Atherosclerosis, 222, pp. 402 - 408, http://dx.doi.org/10.1016/j.atherosclerosis.2012.03.006

Rye KA; Barter PJ, 2012, 'The inhibition of cholesteryl ester transfer protein: A long and winding road', Journal of Lipid Research, 53, pp. 1039 - 1041, http://dx.doi.org/10.1194/jlr.E027334

Huijgen R; Boekholdt SM; Arsenault BJ; Bao W; Davaine JM; Tabet F; Petrides F; Rye KA; Demicco DA; Barter PJ; Kastelein JJP; Lambert G, 2012, 'Plasma PCSK9 levels and clinical outcomes in the TNT (Treating to New Targets) trial: A nested case-control study', Journal of the American College of Cardiology, 59, pp. 1778 - 1784, http://dx.doi.org/10.1016/j.jacc.2011.12.043

Tso C; Rye KA; Barter P, 2012, 'Phenotypic and functional changes in blood monocytes following adherence to endothelium', PLoS ONE, 7, http://dx.doi.org/10.1371/journal.pone.0037091

Drew BG; Rye KA; Duffy SJ; Barter P; Kingwell BA, 2012, 'The emerging role of HDL in glucose metabolism', Nature Reviews Endocrinology, 8, pp. 237 - 245, http://dx.doi.org/10.1038/nrendo.2011.235

Gao X; Gu H; Li G; Rye KA; Zhang DW, 2012, 'Identification of an amino acid residue in ATP-binding cassette transport G1 critical for mediating cholesterol efflux', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1821, pp. 552 - 559, http://dx.doi.org/10.1016/j.bbalip.2011.07.012

Rye KA; Barter PJ, 2012, 'Predictive value of different HDL particles for the protection against or risk of coronary heart disease', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1821, pp. 473 - 480, http://dx.doi.org/10.1016/j.bbalip.2011.10.012

Wu BJ; Chen K; Barter PJ; Rye KA, 2012, 'Niacin inhibits vascular inflammation via the induction of heme oxygenase-1', Circulation, 125, pp. 150 - 158, http://dx.doi.org/10.1161/CIRCULATIONAHA.111.053108

Zhang L; Yan F; Zhang S; Lei D; Charles MA; Cavigiolio G; Oda M; Krauss RM; Weisgraber KH; Rye KA; Pownall HJ; Qiu X; Ren G, 2012, 'Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein', Nature Chemical Biology, 8, pp. 342 - 349, http://dx.doi.org/10.1038/nchembio.796

Charlton F; Xu B; Makris A; Rye K-A; Hennessy A, 2012, '977 HIGH DENSITY LIPOPROTEIN (HDL) AND ITS COMPONENTS protect normal integration of the trophoblast into endothelial cellular networks in an in vitro model of Preeclampsia', Journal of Hypertension, 30, pp. e277 - e277, http://dx.doi.org/10.1097/01.hjh.0000420924.18289.dc

Charlton F; Xu B; Makris A; Rye K-A; Hennessy A, 2012, '978 Molecular changes underlying apolipoprotein (apo)A-I protection of normal integration of the trophoblast into endothelial cellular networks in an in vitro model of preeclampsia', Journal of Hypertension, 30, pp. e282 - e283, http://dx.doi.org/10.1097/01.hjh.0000420923.10665.61

Cakan Y; Tabet F; Lau E; Celermajer DS; Barter PJ; Rye K-A, 2012, 'Abstract 106: Corticosteroid Treatment Induces Structural and Functional Changes in High-Density Lipoproteins', Arteriosclerosis, Thrombosis, and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a106

Bisoendial R; Weninger W; Petrides F; Tabet F; Tak PP; Rye KA, 2012, 'Abstract 305: HDL Antagonizes the Defects in the Lymphatic System that Contribute to the Pathogenesis of Rheumatoid Arthritis', Arteriosclerosis, Thrombosis, and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a305

Cochran BJ; Rye K-A, 2012, 'Abstract 34: Apolipoprotein A-I Increases Insulin Secretion from β-cells via a Protein Kinase A Dependent Mechanism', Arteriosclerosis, Thrombosis, and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a34

Ren G; Zhang L; Yan F; Zhang S; Lei D; Charles MA; Cavigiolio G; Oda M; Krauss RM; Weisgraber KH; Rye K-A; Pownall HJ; Qiu X, 2012, 'Abstract 46: Cholesteryl Ester Transfer Protein Interactions with Lipoproteins: Insights into Mechanisms by Electron Microscopy and Molecular Dynamics Simulation', Arteriosclerosis, Thrombosis, and Vascular Biology, 32, http://dx.doi.org/10.1161/atvb.32.suppl_1.a46

Charlton F; Xu B; Makris A; Hennessy A; Rye K-A, 2012, 'OS041. Apolipoprotein A-I protects normal integration of the trophoblast into endothelial cellular networks in an in vitro model of preeclampsia.', Pregnancy Hypertens, 2, pp. 198 - 199, http://dx.doi.org/10.1016/j.preghy.2012.04.042

Tso C; Rye K; Barter P, 2012, 'The Effects of ApoA-I, A-II and A-IV on Endothelium-generation from Human Peripheral Blood Mononuclear Cells', Heart, Lung and Circulation, 21, pp. S24 - S24, http://dx.doi.org/10.1016/j.hlc.2012.05.064

Barter P; Rye KA, 2011, 'Cholesteryl ester transfer protein inhibition to reduce cardiovascular risk: Where are we now?', Trends in Pharmacological Sciences, 32, pp. 694 - 699, http://dx.doi.org/10.1016/j.tips.2011.07.004

Ong KL; Barter PJ; Rye KA, 2011, 'Response to statin use and serum bilirubin levels', Atherosclerosis, 219, pp. 392, http://dx.doi.org/10.1016/j.atherosclerosis.2011.09.007

Di Bartolo BA; Vanags LZ; Tan JT; Bao S; Rye KA; Barter PJ; Bursill CA, 2011, 'The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit.', Lipids in health and disease, 10, pp. 224, http://dx.doi.org/10.1186/1476-511X-10-224

Ong KL; Tso AWK; Xu A; Law LSC; Li M; Wat NMS; Rye KA; Lam TH; Cheung BMY; Lam KSL, 2011, 'Evaluation of the combined use of adiponectin and C-reactive protein levels as biomarkers for predicting the deterioration in glycaemia after a median of 5.4 years', Diabetologia, 54, pp. 2552 - 2560, http://dx.doi.org/10.1007/s00125-011-2227-0

Barter PJ; Rye KA; Tardif JC; Waters DD; Matthijs BS; Breazna A; Kastelein JJP, 2011, 'Effect of torcetrapib on glucose, insulin, and hemoglobin a1c in subjects in the investigation of lipid level management to understand its impact in atherosclerotic events (Illuminate) Trial', Circulation, 124, pp. 555 - 562, http://dx.doi.org/10.1161/CIRCULATIONAHA.111.018259

Di Bartolo BA; Nicholls SJ; Bao S; Rye KA; Heather AK; Barter PJ; Bursill C, 2011, 'The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins', Atherosclerosis, 217, pp. 395 - 400, http://dx.doi.org/10.1016/j.atherosclerosis.2011.04.001

Kitajima K; Miura SI; Yamauchi T; Uehara Y; Kiya Y; Rye KA; Kadowaki T; Saku K, 2011, 'Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells', Biochemical and Biophysical Research Communications, 411, pp. 305 - 311, http://dx.doi.org/10.1016/j.bbrc.2011.06.131

Reimers GJ; Jackson CL; Rickards J; Chan PY; Cohn JS; Rye KA; Barter PJ; Rodgers KJ, 2011, 'Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I', Cardiovascular Research, 91, pp. 37 - 44, http://dx.doi.org/10.1093/cvr/cvr057

Wood P; Mulay V; Darabi M; Chan KC; Heeren J; Pol A; Lambert G; Rye KA; Enrich C; Grewal T, 2011, 'Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI', Journal of Biological Chemistry, 286, pp. 23077 - 23092, http://dx.doi.org/10.1074/jbc.M111.236398

Tabet F; Lambert G; Cuesta Torres LF; Hou L; Sotirchos I; Touyz RM; Jenkins AJ; Barter PJ; Rye KA, 2011, 'Lipid-free apolipoprotein A-I and discoidal reconstituted high-density lipoproteins differentially inhibit glucose-induced oxidative stress in human macrophages', Arteriosclerosis, Thrombosis, and Vascular Biology, 31, pp. 1192 - 1200, http://dx.doi.org/10.1161/ATVBAHA.110.222000

Wu Z; Gogonea V; Lee X; May RP; Pipich V; Wagner MA; Undurti A; Tallant TC; Baleanu-Gogonea C; Charlton F; Ioffe A; DiDonato JA; Rye KA; Hazen SL, 2011, 'The low resolution structure of ApoA1 in spherical high density lipoprotein revealed by small angle neutron scattering', Journal of Biological Chemistry, 286, pp. 12495 - 12508, http://dx.doi.org/10.1074/jbc.M110.209130

Ong KL; Wu BJ; Cheung BMY; Barter PJ; Rye KA, 2011, 'Association of lower total bilirubin level with statin usage: The United States National Health and Nutrition Examination Survey 1999-2008', Atherosclerosis, 219, pp. 728 - 733, http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.094

Zhang L; Song J; Cavigiolio G; Ishida BY; Zhang S; Kane JP; Weisgraber KH; Oda MN; Rye KA; Pownall HJ; Ren G, 2011, 'Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy', Journal of Lipid Research, 52, pp. 175 - 184, http://dx.doi.org/10.1194/jlr.D010959

Elliott DA; Tsoi K; Holinkova S; Chan LL; Kim WS; Halliday GM; Rye K; Garner B, 2011, 'Isoform-specific proteolysis of apolipoprotein-E in the brain', Neurobiology of Aging, 32, pp. 257 - 271, http://dx.doi.org/10.1016/j.neurobiolaging.2009.02.006

Tso C; Rye K; Barter P, 2011, 'Lipid-free Apolipoprotein A-I Enhances Endothelium generation from Human Blood Monocytes', Heart, Lung and Circulation, 20, pp. S15 - S15, http://dx.doi.org/10.1016/j.hlc.2011.05.038

Hadfield KA; Pattison DI; Rye K-A; Davies MJ; Hawkins CL, 2011, 'Oxidation of Lipid-Free Apolipoprotein A-I by Thiocyanate-Derived Oxidants Compromises its Ability To Efflux Cholesterol', Free Radical Biology and Medicine, 51, pp. S41 - S41, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.100

Bursill CA; Castro ML; Beattie DT; Nakhla S; Van Der Vorst E; Heather AK; Barter PJ; Rye KA, 2010, 'High-density lipoproteins suppress chemokines and chemokine receptors in vitro and in vivo', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, pp. 1773 - 1778, http://dx.doi.org/10.1161/ATVBAHA.110.211342

Wu BJ; Yan L; Charlton F; Witting P; Barter PJ; Rye KA, 2010, 'Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, pp. 968 - 975, http://dx.doi.org/10.1161/ATVBAHA.109.201129

Imaizumi S; Kiya Y; Miura SI; Zhang B; Matsuo Y; Uehara Y; Rye KA; Saku K, 2010, 'Pharmacological intervention using reconstituted high-density lipoprotein changes in the lipid profile in spontaneously hypersensitive rats', Clinical and Experimental Hypertension, 32, pp. 202 - 208, http://dx.doi.org/10.3109/10641960903265196

Nobécourt E; Tabet F; Lambert G; Puranik R; Bao S; Yan L; Davies MJ; Brown BE; Jenkins AJ; Dusting GJ; Bonnet DJ; Curtiss LK; Barter PJ; Rye KA, 2010, 'Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, pp. 766 - 772, http://dx.doi.org/10.1161/ATVBAHA.109.201715

de Souza JA; Vindis C; Nègre-Salvayre A; Rye KA; Couturier M; Therond P; Chantepie S; Salvayre R; Chapman MJ; Kontush A, 2010, 'Small, dense HDL 3 particles attenuate apoptosis in endothelial cells: Pivotal role of apolipoprotein A-I', Journal of Cellular and Molecular Medicine, 14, pp. 608 - 620, http://dx.doi.org/10.1111/j.1582-4934.2009.00713.x

Chan DC; Hamilton SJ; Rye KA; Chew GT; Jenkins AJ; Lambert G; Watts GF, 2010, 'Fenofibrate concomitantly decreases serum proprotein convertase subtilisin/kexin type 9 and very-low-density lipoprotein particle concentrations in statin-treated type 2 diabetic patients', Diabetes, Obesity and Metabolism, 12, pp. 752 - 756, http://dx.doi.org/10.1111/j.1463-1326.2010.01229.x

Tabet F; Remaley AT; Segaliny AI; Millet J; Yan L; Nakhla S; Barter PJ; Rye KA; Lambert G, 2010, 'The 5A apolipoprotein A-I mimetic peptide displays antiinflammatory and antioxidant properties in vivo and in vitro', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, pp. 246 - 252, http://dx.doi.org/10.1161/ATVBAHA.109.200196

Zhang L; Cavigiolio G; Oda M; Rye K-A; Ren G, 2010, 'A Method to Study the Time-Dependent Remodeling of High Density Lipoproteins by Individual-Particle Electron Cryo-Tomography', Biophysical Journal, 98, pp. 440a - 440a, http://dx.doi.org/10.1016/j.bpj.2009.12.2390

Patel S; Di bartolo B; Nakhla S; Heather A; Mitchell T; Jessup W; Celermajer D; Barter P; Rye K, 2010, 'Anti-inflammatory effects of apolipoprotein A-I in the rabbit', Atherosclerosis, 212, pp. 392 - 397

Ren G; Zhang S; Cavigiolio G; Lei D; Oda M; Weisgraber KH; Rye K-A; Pownall HJ; Qiu X, 2010, 'Cholesteryl Ester Transfer Protein Penetrates Lipoproteins For Cholesteryl Ester Transfer', Biophysical Journal, 98, pp. 36a - 36a, http://dx.doi.org/10.1016/j.bpj.2009.12.212

Fryirs MA; Barter P; Appavoo M; Tuch BE; Tabet F; Heather AK; Rye K, 2010, 'Effects of High-Density Lipoproteins on Pancreatic -Cell Insulin Secretion', Arteriosclerosis, Thrombosis and Vascular Biology, 30, pp. 1642 - 1648

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