By Professor Kerry-Anne Rye

Journal articles

Matsuo Y; Miura S; Kiya Y; Uehara Y; Imaizumi S; Rye KA; Saku K, 2006, 'Th-P15:197 Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation', Atherosclerosis Supplements, 7, pp. 536 - 536, http://dx.doi.org/10.1016/s1567-5688(06)82156-2

Heather AK; McGrath KC-Y; Puranik R; Tsatralis T; Celermajer D; Barter P; Rye K, 2006, 'Tu-P7:218 HDL exerts novel anti-inflammatory effects on endothelial cells via the suppression on NFKB', Atherosclerosis Supplements, 7, pp. 232 - 232, http://dx.doi.org/10.1016/s1567-5688(06)80922-0

Rye K-A; Puranik R; Nobecourt E; Bao S; Nicholls SJ; Barter PJ, 2006, 'Tu-W16:1 HDL and the inhibition of inflammation in vivo', Atherosclerosis Supplements, 7, pp. 152 - 152, http://dx.doi.org/10.1016/s1567-5688(06)80597-0

Barrett PHR; Kee P; Caiazza D; Rye KA; Morehouse LA; Barter PJ, 2006, 'We-W38:5 Effect of inhibiting cholesteryl ester transfer protein on the kinetics of HDL cholesteryl ester transport in plasma: In vivo studies in rabbits', Atherosclerosis Supplements, 7, pp. 322 - 322, http://dx.doi.org/10.1016/s1567-5688(06)81285-7

Jahangiri A; Rader DJ; Marchadier D; Curtiss LK; Bonnet DJ; Rye KA, 2005, 'Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I', Journal of Lipid Research, 46, pp. 896 - 903, http://dx.doi.org/10.1194/jlr.M400212-JLR200

Nicholls SJ; Cutri B; Worthley SG; Kee P; Rye KA; Bao S; Barter PJ, 2005, 'Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits', Arteriosclerosis Thrombosis and Vascular Biology, 25, pp. 2416 - 2421, http://dx.doi.org/10.1161/01.ATV.0000184760.95957.d6

Jänis MT; Metso J; Lankinen H; Strandin T; Olkkonen VM; Rye KA; Jauhiainen M; Ehnholm C, 2005, 'Apolipoprotein E activates the low-activity form of human phospholipid transfer protein', Biochemical and Biophysical Research Communications, 331, pp. 333 - 340, http://dx.doi.org/10.1016/j.bbrc.2005.03.164

Nicholls SJ; Dusting GJ; Cutri B; Bao S; Drummond GR; Rye KA; Barter PJ, 2005, 'Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits', Circulation, 111, pp. 1543 - 1550, http://dx.doi.org/10.1161/01.CIR.0000159351.95399.50

Nicholls SJ; Rye KA; Barter PJ, 2005, 'High-density lipoproteins as therapeutic targets', Current Opinion in Lipidology, 16, pp. 345 - 349, http://dx.doi.org/10.1097/01.mol.0000169356.58513.25

Gelissen I; Packianathan M; Rye K; Harris ML; Quinn CM; Kritharides L; Jessup W, 2005, 'ABCG1 mediated cholesterol efflux from cells', Atherosclerosis Supplements, 6, pp. 55 - 55

Grewal T; Evans R; Rentero C; Tebar F; Cubells L; de Diego I; Kirchhoff M; Hughes WE; Heeren J; Rye K; Rinninger F; Daly RJ; Pol A; Enrich C, 2005, 'Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity', Oncogene, 24, pp. 5809 - 5820

Raftery MJ; Campbell R; Glaros EN; Rye K; Halliday GM; Jessup W; Garner B, 2005, 'Phosphorylation of apolipoprotein-E at an atypical protein kinase CK2 PSD/E site in vitro.', Biochemistry, 44, pp. 7346 - 7353

Barter PJ; Nicholls S; Rye KA; Anantharamaiah GM; Navab M; Fogelman AM, 2004, 'Antiinflammatory properties of HDL', Circulation Research, 95, pp. 764 - 772, http://dx.doi.org/10.1161/01.RES.0000146094.59640.13

Hime NJ; Drew KJ; Hahn C; Barter PJ; Rye KA, 2004, 'Apolipoprotein E enhances hepatic lipase-mediated hydrolysis of reconstituted high-density lipoprotein phospholipid and triacylglycerol in an isoform-dependent manner', Biochemistry, 43, pp. 12306 - 12314, http://dx.doi.org/10.1021/bi036305i

Caiazza D; Jahangiri A; Rader DJ; Marchadier D; Rye KA, 2004, 'Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted high-density lipoproteins', Biochemistry, 43, pp. 11898 - 11905, http://dx.doi.org/10.1021/bi049776t

Wadham C; Albanese N; Roberts J; Wang L; Bagley CJ; Gamble JR; Rye KA; Barter PJ; Vadas MA; Xia P, 2004, 'High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity', Circulation, 109, pp. 2116 - 2122, http://dx.doi.org/10.1161/01.CIR.0000127419.45975.26

Rye KA; Barter PJ, 2004, 'Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I', Arteriosclerosis Thrombosis and Vascular Biology, 24, pp. 421 - 428, http://dx.doi.org/10.1161/01.ATV.0000104029.74961.f5

Kockx M; Rye K; Gaus K; Quinn CM; Wright J; Sloane T; Sviridov D; Fu YL; Sullivan D; Burnett J; Rust S; Assmann G; Anantharamaiah G; Palgunachari M; Katz S; Phillips MA; Dean R; Jessup W; Kritharides L, 2004, 'Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux', The Journal of Biological Chemistry, 279, pp. 25966 - 25977

Wadham C; Albanese N; Roberts J; Wang L; Bagley C; Gamble J; Rye K-A; Barter P; Vadas M; Xia P, 2004, 'HIGH-DENSITY LIPOPROTEINS NEUTRALISE C-REACTIVE PROTEIN PROINFLAMMATORY ACTIVITY', Cardiovascular Pathology, 13, pp. 31 - 31, http://dx.doi.org/10.1016/j.carpath.2004.03.085

Heeren J; Grewal T; Laatsch A; Becker NG; Rinninger F; Rye K; Beisiegel U, 2004, 'Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation', The Journal of Biological Chemistry, 279, pp. 55483 - 55492

Duong MN; Psaltis M; Rader DJ; Marchadier D; Barter PJ; Rye KA, 2003, 'Evidence That Hepatic Lipase and Endothelial Lipase Have Different Substrate Specificities for High-Density Lipoprotein Phospholipids', Biochemistry, 42, pp. 13778 - 13785, http://dx.doi.org/10.1021/bi034990n

Rye KA; Wee K; Curtiss LK; Bonnet DJ; Barter PJ, 2003, 'Apolipoprotein A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation', Journal of Biological Chemistry, 278, pp. 22530 - 22536, http://dx.doi.org/10.1074/jbc.M213250200

Hime N; Drew K; Hahn C; Rye K-A, 2003, '3P-0730 Influence of apolipoprotein E isoforms on hepatic lipase-mediated phospholipid and triacylglycerol hydrolysis in reconstituted high density lipoproteins', Atherosclerosis Supplements, 4, pp. 222 - 222, http://dx.doi.org/10.1016/s1567-5688(03)90949-4

Hime N; Wee K; Barter P; Rye K-A, 2003, '3P-0731 In vivo formation of high density lipoproteins containing both apolipoprotein A-I and apolipoprotein A-II in the rabbit', Atherosclerosis Supplements, 4, pp. 222 - 222, http://dx.doi.org/10.1016/s1567-5688(03)90950-0

Jahangiri A; Rader D; Marchadier D; Rye KA, 2003, 'Apolipoproteins regulate the remodelling of high density lipoproteins by endothelial lipase', ATHEROSCLEROSIS SUPPLEMENTS, 4, pp. 300 - 300, http://dx.doi.org/10.1016/S1567-5688(03)91283-9

Kee P; Rye KA; Taylor JL; Barrett PHR; Barter PJ, 2002, 'Metabolism of ApoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: Studies in wild-type and hepatic lipase transgenic rabbits', Arteriosclerosis Thrombosis and Vascular Biology, 22, pp. 1912 - 1917, http://dx.doi.org/10.1161/01.ATV.0000038485.94020.7F

Barter PJ; Baker PW; Rye KA, 2002, 'Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells', Current Opinion in Lipidology, 13, pp. 285 - 288, http://dx.doi.org/10.1097/00041433-200206000-00008

Rye K; Duong M; Psaltis MK; Curtiss LK; Bonnet DJ; Stocker R; Barter P, 2002, 'Evidence that Phospholipids Play a Key Role in Pre-B ApoA-I Formation and High-Density Lipoprotein Remodeling', Biochemistry, 41, pp. 12538 - 12545

Barter PJ; Rye KA, 2001, 'Cholesteryl ester transfer protein, high density lipoprotein and arterial disease', Current Opinion in Lipidology, 12, pp. 377 - 382, http://dx.doi.org/10.1097/00041433-200108000-00002

Settasatian N; Duong MN; Curtiss LK; Ehnholm C; Jauhiainen M; Huuskonen J; Rye KA, 2001, 'The Mechanism of the Remodeling of High Density Lipoproteins by Phospholipid Transfer Protein', Journal of Biological Chemistry, 276, pp. 26898 - 26905, http://dx.doi.org/10.1074/jbc.M010708200

Clay MA; Pyle DH; Rye KA; Vadas MA; Gamble JR; Barter PJ, 2001, 'Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins', Atherosclerosis, 157, pp. 23 - 29, http://dx.doi.org/10.1016/S0021-9150(00)00659-6

Hime NJ; Barter PJ; Rye KA, 2001, 'Evidence that apolipoprotein A-I facilitates hepatic lipase-mediated phospholipid hydrolysis in reconstituted HDL containing apolipoprotein A-II', Biochemistry, 40, pp. 5496 - 5505, http://dx.doi.org/10.1021/bi0016671

Ashby D; Gamble J; Vadas M; Fidge N; Siggins S; Rye KA; Barter PJ, 2001, 'Lack of effect of serum amyloid A (SAA) on the ability of high-density lipoproteins to inhibit endothelial cell adhesion molecule expression', Atherosclerosis, 154, pp. 113 - 121, http://dx.doi.org/10.1016/S0021-9150(00)00437-8

Curtiss LK; Bonnet DJ; Rye KA, 2000, 'The conformation of apolipoprotein A-I in high-density lipoproteins is influenced by core lipid composition and particle size: A surface plasmon resonance study', Biochemistry, 39, pp. 5712 - 5721, http://dx.doi.org/10.1021/bi992902m

Clay MA; Pyle DH; Rye KA; Barter PJ, 2000, 'Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase', Journal of Biological Chemistry, 275, pp. 9019 - 9025, http://dx.doi.org/10.1074/jbc.275.12.9019

Rye KA; My Ngan Duong , 2000, 'Influence of phospholipid depletion on the size, structure, and remodeling of reconstituted high density lipoproteins', Journal of Lipid Research, 41, pp. 1640 - 1650, http://dx.doi.org/10.1016/s0022-2275(20)31997-0

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 2000, 'Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression', Journal of Lipid Research, 41, pp. 1261 - 1267, http://dx.doi.org/10.1016/s0022-2275(20)33434-9

Settasatian N; Curtiss LK; Ehnholm C; Jauhiainen M; Rye K-A, 2000, 'Influence of triglyceride enrichment on the remodelling of high density lipoproteins by PLTP', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80823-0

Baker PW; Rye K-A; Gamble JR; Vadas MA; Barter PJ, 2000, 'Inhibition of endothelial cell adhesion molecule expression by reconstituted high-density lipoproteins: Determinants and characteristics', Atherosclerosis, 151, pp. 190 - 190, http://dx.doi.org/10.1016/s0021-9150(00)80865-5

Panzenbock U; Kritharides L; Raftery MJ; Rye K; Stocker R, 2000, 'Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I', The Journal of Biological Chemistry, pp. 19536 - 19544

Panzenböck U; Raftery M; Kritharides L; Rye K-A; Perry R; Francis G; Stocker R, 2000, 'Oxidation of specific Met residues does not decrease anti-atherogenic activities of apolipoprotein A-I', Atherosclerosis, 151, pp. 165 - 165, http://dx.doi.org/10.1016/s0021-9150(00)80748-0

Hime NJ; Barter PJ; Rye K-A, 2000, 'The influence of apolipoproteins on hepatic lipase-mediated phospholipid hydrolysis in reconstituted high density lipoproteins', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80824-2

Duong M; Rye KA, 2000, 'The influence of phospholipid acyl chain composition on the hepatic lipase-mediated hydrolysis of HDL phospholipids', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80822-9

Xia P; Vadas MA; Rye KA; Barter PJ; Gamble JR, 1999, 'High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against a therosclerosis by HDL', Journal of Biological Chemistry, 274, pp. 33143 - 33147, http://dx.doi.org/10.1074/jbc.274.46.33143

Rye KA; Clay MA; Barter PJ, 1999, 'Remodelling of high density lipoproteins by plasma factors', Atherosclerosis, 145, pp. 227 - 238, http://dx.doi.org/10.1016/S0021-9150(99)00150-1

Panzenboeck U; Rye KA; Kritharides L; Stocker R, 1999, 'Selective oxidation of methionine residues enhances rather than decreases potential anti-atherogenic properties of apolipoprotein AI', ATHEROSCLEROSIS, 144, pp. 6 - 6, http://dx.doi.org/10.1016/S0021-9150(99)80017-3

Clay MA; Cehic DA; Pyle DH; Rye KA; Barter PJ, 1999, 'Formation of apolipoprotein-specific high-density lipoprotein particles from lipid-free apolipoproteins A-I and A-II', Biochemical Journal, 337, pp. 445 - 451, http://dx.doi.org/10.1042/0264-6021:3370445

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 1999, 'Ability of reconstituted high density lipoproteins to inhibit cytokine- induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells', Journal of Lipid Research, 40, pp. 345 - 353, http://dx.doi.org/10.1016/s0022-2275(20)33375-7

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1999, 'Oxysterol efflux from macrophage foam cells: The essential role of acceptor phospholipid', Journal of Lipid Research, 40, pp. 1636 - 1646, http://dx.doi.org/10.1016/s0022-2275(20)33409-x

Xia P; Gamble JR; Rye KA; Wang L; Hii CST; Cockerill P; Khew-Goodall Y; Bert AG; Barter PJ; Vadas MA, 1998, 'Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 14196 - 14201, http://dx.doi.org/10.1073/pnas.95.24.14196

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