By Professor Kerry-Anne Rye

Journal articles

Hime NJ; Drew KJ; Hahn C; Barter PJ; Rye KA, 2004, 'Apolipoprotein E enhances hepatic lipase-mediated hydrolysis of reconstituted high-density lipoprotein phospholipid and triacylglycerol in an isoform-dependent manner', Biochemistry, 43, pp. 12306 - 12314, http://dx.doi.org/10.1021/bi036305i

Caiazza D; Jahangiri A; Rader DJ; Marchadier D; Rye KA, 2004, 'Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted high-density lipoproteins', Biochemistry, 43, pp. 11898 - 11905, http://dx.doi.org/10.1021/bi049776t

Wadham C; Albanese N; Roberts J; Wang L; Bagley CJ; Gamble JR; Rye KA; Barter PJ; Vadas MA; Xia P, 2004, 'High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity', Circulation, 109, pp. 2116 - 2122, http://dx.doi.org/10.1161/01.CIR.0000127419.45975.26

Rye KA; Barter PJ, 2004, 'Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I', Arteriosclerosis, Thrombosis, and Vascular Biology, 24, pp. 421 - 428, http://dx.doi.org/10.1161/01.ATV.0000104029.74961.f5

Kockx M; Rye K; Gaus K; Quinn CM; Wright J; Sloane T; Sviridov D; Fu YL; Sullivan D; Burnett J; Rust S; Assmann G; Anantharamaiah G; Palgunachari M; Katz S; Phillips MA; Dean R; Jessup W; Kritharides L, 2004, 'Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux', The Journal of Biological Chemistry, 279, pp. 25966 - 25977

Wadham C; Albanese N; Roberts J; Wang L; Bagley C; Gamble J; Rye K-A; Barter P; Vadas M; Xia P, 2004, 'HIGH-DENSITY LIPOPROTEINS NEUTRALISE C-REACTIVE PROTEIN PROINFLAMMATORY ACTIVITY', Cardiovascular Pathology, 13, pp. 31 - 31, http://dx.doi.org/10.1016/j.carpath.2004.03.085

Heeren J; Grewal T; Laatsch A; Becker NG; Rinninger F; Rye K; Beisiegel U, 2004, 'Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation', The Journal of Biological Chemistry, 279, pp. 55483 - 55492

Duong MN; Psaltis M; Rader DJ; Marchadier D; Barter PJ; Rye KA, 2003, 'Evidence That Hepatic Lipase and Endothelial Lipase Have Different Substrate Specificities for High-Density Lipoprotein Phospholipids', Biochemistry, 42, pp. 13778 - 13785, http://dx.doi.org/10.1021/bi034990n

Rye KA; Wee K; Curtiss LK; Bonnet DJ; Barter PJ, 2003, 'Apolipoprotein A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation', Journal of Biological Chemistry, 278, pp. 22530 - 22536, http://dx.doi.org/10.1074/jbc.M213250200

Hime N; Drew K; Hahn C; Rye K-A, 2003, '3P-0730 Influence of apolipoprotein E isoforms on hepatic lipase-mediated phospholipid and triacylglycerol hydrolysis in reconstituted high density lipoproteins', Atherosclerosis Supplements, 4, pp. 222 - 222, http://dx.doi.org/10.1016/s1567-5688(03)90949-4

Hime N; Wee K; Barter P; Rye K-A, 2003, '3P-0731 In vivo formation of high density lipoproteins containing both apolipoprotein A-I and apolipoprotein A-II in the rabbit', Atherosclerosis Supplements, 4, pp. 222 - 222, http://dx.doi.org/10.1016/s1567-5688(03)90950-0

Jahangiri A; Rader D; Marchadier D; Rye K-A, 2003, '4P-1026 Apolipoproteins regulate the remodelling of high density lipoproteins by endothelial lipase', Atherosclerosis Supplements, 4, pp. 300 - 300, http://dx.doi.org/10.1016/s1567-5688(03)91283-9

Kee P; Rye KA; Taylor JL; Barrett PHR; Barter PJ, 2002, 'Metabolism of ApoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: Studies in wild-type and hepatic lipase transgenic rabbits', Arteriosclerosis, Thrombosis, and Vascular Biology, 22, pp. 1912 - 1917, http://dx.doi.org/10.1161/01.ATV.0000038485.94020.7F

Barter PJ; Baker PW; Rye KA, 2002, 'Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells', Current Opinion in Lipidology, 13, pp. 285 - 288, http://dx.doi.org/10.1097/00041433-200206000-00008

Rye K; Duong M; Psaltis MK; Curtiss LK; Bonnet DJ; Stocker R; Barter P, 2002, 'Evidence that Phospholipids Play a Key Role in Pre-B ApoA-I Formation and High-Density Lipoprotein Remodeling', Biochemistry, 41, pp. 12538 - 12545

Barter PJ; Rye KA, 2001, 'Cholesteryl ester transfer protein, high density lipoprotein and arterial disease', Current Opinion in Lipidology, 12, pp. 377 - 382, http://dx.doi.org/10.1097/00041433-200108000-00002

Settasatian N; Duong MN; Curtiss LK; Ehnholm C; Jauhiainen M; Huuskonen J; Rye KA, 2001, 'The Mechanism of the Remodeling of High Density Lipoproteins by Phospholipid Transfer Protein', Journal of Biological Chemistry, 276, pp. 26898 - 26905, http://dx.doi.org/10.1074/jbc.M010708200

Clay MA; Pyle DH; Rye KA; Vadas MA; Gamble JR; Barter PJ, 2001, 'Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins', Atherosclerosis, 157, pp. 23 - 29, http://dx.doi.org/10.1016/S0021-9150(00)00659-6

Hime NJ; Barter PJ; Rye KA, 2001, 'Evidence that apolipoprotein A-I facilitates hepatic lipase-mediated phospholipid hydrolysis in reconstituted HDL containing apolipoprotein A-II', Biochemistry, 40, pp. 5496 - 5505, http://dx.doi.org/10.1021/bi0016671

Ashby D; Gamble J; Vadas M; Fidge N; Siggins S; Rye KA; Barter PJ, 2001, 'Lack of effect of serum amyloid A (SAA) on the ability of high-density lipoproteins to inhibit endothelial cell adhesion molecule expression', Atherosclerosis, 154, pp. 113 - 121, http://dx.doi.org/10.1016/S0021-9150(00)00437-8

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 2000, 'Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression', Journal of Lipid Research, 41, pp. 1261 - 1267

Curtiss LK; Bonnet DJ; Rye KA, 2000, 'The conformation of apolipoprotein A-I in high-density lipoproteins is influenced by core lipid composition and particle size: A surface plasmon resonance study', Biochemistry, 39, pp. 5712 - 5721, http://dx.doi.org/10.1021/bi992902m

Clay MA; Pyle DH; Rye KA; Barter PJ, 2000, 'Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase', Journal of Biological Chemistry, 275, pp. 9019 - 9025, http://dx.doi.org/10.1074/jbc.275.12.9019

Rye KA; My Ngan Duong , 2000, 'Influence of phospholipid depletion on the size, structure, and remodeling of reconstituted high density lipoproteins', Journal of Lipid Research, 41, pp. 1640 - 1650

Settasatian N; Curtiss LK; Ehnholm C; Jauhiainen M; Rye K-A, 2000, 'Influence of triglyceride enrichment on the remodelling of high density lipoproteins by PLTP', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80823-0

Baker PW; Rye K-A; Gamble JR; Vadas MA; Barter PJ, 2000, 'Inhibition of endothelial cell adhesion molecule expression by reconstituted high-density lipoproteins: Determinants and characteristics', Atherosclerosis, 151, pp. 190 - 190, http://dx.doi.org/10.1016/s0021-9150(00)80865-5

Panzenbock U; Kritharides L; Raftery MJ; Rye K; Stocker R, 2000, 'Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I', The Journal of Biological Chemistry, pp. 19536 - 19544

Panzenböck U; Raftery M; Kritharides L; Rye K-A; Perry R; Francis G; Stocker R, 2000, 'Oxidation of specific Met residues does not decrease anti-atherogenic activities of apolipoprotein A-I', Atherosclerosis, 151, pp. 165 - 165, http://dx.doi.org/10.1016/s0021-9150(00)80748-0

Hime NJ; Barter PJ; Rye K-A, 2000, 'The influence of apolipoproteins on hepatic lipase-mediated phospholipid hydrolysis in reconstituted high density lipoproteins', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80824-2

Duong M; Rye KA, 2000, 'The influence of phospholipid acyl chain composition on the hepatic lipase-mediated hydrolysis of HDL phospholipids', Atherosclerosis, 151, pp. 181 - 181, http://dx.doi.org/10.1016/s0021-9150(00)80822-9

Xia P; Vadas MA; Rye KA; Barter PJ; Gamble JR, 1999, 'High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against a therosclerosis by HDL', Journal of Biological Chemistry, 274, pp. 33143 - 33147, http://dx.doi.org/10.1074/jbc.274.46.33143

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1999, 'Oxysterol efflux from macrophage foam cells: The essential role of acceptor phospholipid', Journal of Lipid Research, 40, pp. 1636 - 1646

Rye KA; Clay MA; Barter PJ, 1999, 'Remodelling of high density lipoproteins by plasma factors', Atherosclerosis, 145, pp. 227 - 238, http://dx.doi.org/10.1016/S0021-9150(99)00150-1

Panzenboeck U; Rye KA; Kritharides L; Stocker R, 1999, 'Selective oxidation of methionine residues enhances rather than decreases potential anti-atherogenic properties of apolipoprotein AI', ATHEROSCLEROSIS, 144, pp. 6 - 6, http://dx.doi.org/10.1016/S0021-9150(99)80017-3

Baker PW; Rye KA; Gamble JR; Vadas MA; Barter PJ, 1999, 'Ability of reconstituted high density lipoproteins to inhibit cytokine- induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells', Journal of Lipid Research, 40, pp. 345 - 353

Clay MA; Cehic DA; Pyle DH; Rye KA; Barter PJ, 1999, 'Formation of apolipoprotein-specific high-density lipoprotein particles from lipid-free apolipoproteins A-I and A-II', Biochemical Journal, 337, pp. 445 - 451, http://dx.doi.org/10.1042/0264-6021:3370445

Xia P; Gamble JR; Rye KA; Wang L; Hii CST; Cockerill P; Khew-Goodall Y; Bert AG; Barter PJ; Vadas MA, 1998, 'Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 14196 - 14201, http://dx.doi.org/10.1073/pnas.95.24.14196

Hime NJ; Barter PJ; Rye KA, 1998, 'The influence of apolipoproteins on the hepatic lipase-mediated hydrolysis of high density lipoprotein phospholipid and triacylglycerol', Journal of Biological Chemistry, 273, pp. 27191 - 27198, http://dx.doi.org/10.1074/jbc.273.42.27191

Garner B; Waldeck AR; Witting PK; Rye KA; Stocker R, 1998, 'Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII', Journal of Biological Chemistry, 273, pp. 6088 - 6095, http://dx.doi.org/10.1074/jbc.273.11.6088

Rye KA; Jauhiainen M; Barter PJ; Ehnholm C, 1998, 'Triglyceride-enrichment of high density lipoproteins enhances their remodelling by phospholipid transfer protein', Journal of Lipid Research, 39, pp. 613 - 622

Ashby DT; Rye KA; Clay MA; Vadas MA; Gamble JR; Barter PJ, 1998, 'Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells', Arteriosclerosis, Thrombosis, and Vascular Biology, 18, pp. 1450 - 1455, http://dx.doi.org/10.1161/01.ATV.18.9.1450

James MJ; Van Reyk D; Rye KA; Dean RT; Cleland LG; Barter PJ; Jessup W, 1998, 'Low density lipoprotein of synovial fluid in inflammatory joint disease is mildly oxidized', Lipids, 33, pp. 1115 - 1121, http://dx.doi.org/10.1007/s11745-998-0313-8

Gelissen IC; Rye KA; Brown AJ; Dean RT; Jessup W, 1997, 'Phospholipid association with apo A-I stimulates oxysterol efflux from macrophage foam cells', ATHEROSCLEROSIS, 134, pp. 367 - 367, http://dx.doi.org/10.1016/S0021-9150(97)89866-8

Rye KA; Hime NJ; Barter PJ, 1997, 'Evidence that cholesteryl ester transfer protein-mediated reductions in reconstituted high density lipoprotein size involve particle fusion', Journal of Biological Chemistry, 272, pp. 3953 - 3960, http://dx.doi.org/10.1074/jbc.272.7.3953

Vadas MA; Gamble JR; Rye K; Barter P, 1997, 'Regulation of leucocyte-endothelial interactions of special relevance to atherogenesis', Clinical and Experimental Pharmacology and Physiology, 24, pp. a33 - a35, http://dx.doi.org/10.1111/j.1440-1681.1997.tb03052.x

Hime NJ; Barter PJ; Rye K-A, 1997, '1.P.41 The influence of apolipoprotein composition on hepatic lipase-mediated phospholipid and triacylglycerol hydrolysis in reconstituted high density lipoproteins', Atherosclerosis, 134, pp. 25 - 25, http://dx.doi.org/10.1016/s0021-9150(97)88220-2

Barter PJ; Rye K-A; Clay MA; Ashby D; Baker P; Xia P; Gamble JR; Vadas MA, 1997, '4.C.4 Anti-atherogenic effects of high density lipoproteins: Mechanisms', Atherosclerosis, 134, pp. 285 - 285, http://dx.doi.org/10.1016/s0021-9150(97)89485-3

Ashby DT; Gamble JR; Vadas MA; Rye K-A; Barter PJ, 1997, '4.P.374 Inhibition of endothelial cell adhesion molecule expression by high density lipoprotein subfractions', Atherosclerosis, 134, pp. 375 - 375, http://dx.doi.org/10.1016/s0021-9150(97)89901-7

Clay MA; Cehic D; Rye K-A; Barter PJ, 1997, '4.P.377 Formation of high density lipoprotein particles containing both apolipoproteins A-I and A-II during incubation in vitro', Atherosclerosis, 134, pp. 376 - 376, http://dx.doi.org/10.1016/s0021-9150(97)89907-8

Liang HQ; Rye KA; Barter PJ, 1996, 'Remodelling of reconstituted high density lipoproteins by lecithin:cholesterol acyltransferase', Journal of Lipid Research, 37, pp. 1962 - 1979

Back to profile page