Professor Poole-Warren leads a research group focussed on design and development of novel materials for neural electrodes and other soft-tissue interfaces, and on 3D engineered neural tissue models. A key theme of her work is on design of new biosynthetic materials and understanding of  material and device interactions with cells and tissues. Throughout her career, she has worked in academia, industry, and government bodies. She was a research professor at the New Jersey Centre for Biomaterials based at Rutgers University in the USA and a preclinical scientist in the biomedical industry working on development of wound dressings and embolic agents for cancer treatment from 1999 to 2001. She also served from 2003 to 2013 as a member of the Australian Government Therapeutic Goods Administration (TGA) statutory expert committee on the safety of medical devices. Between 2005 and 2018, Laura held various leadership appointments at UNSW including Faculty of Engineering Associate Dean Research, Pro Vice-Chancellor, Dean of Graduate Research and Chair of the inaugural Athena SWAN self assessement team (SAT). She was the inaugural Chair of the Australian Council for Graduate Research (ACGR), as well as being the Australian representative on the International Union of Societies of Biomaterials Science and Engineering. Laura was awarded honours in January 2020 as a Member of the Order of Australia (AM) for service to Biomedical Engineering and education, is a Fellow of four academies, ATSE, AIMBE, IUSBSE and the Royal Society of NSW. She is an Associate Editor of Biomaterials, and on the editorial board of the Journal of Neural Engineering.