By Professor Lei Zhang

Journal articles

Wirawan GBS; Schimdt HM; Chan C; Fraser D; Ong JJ; Cassell M; Zhang L; Tieosapjaroen W; Phanuphak N; Tang W; Suwandi N; Green KA; Dobbins T; Bavinton BR, 2025, 'PrEP use and willingness cascades among GBMSM in 15 Asian countries/territories: an analysis of the PrEP APPEAL survey', Journal of the International AIDS Society, 28, pp. e26438, http://dx.doi.org/10.1002/jia2.26438

Lu F; She B; Ji F; Zhang L, 2025, 'Re-Assessing the Non-Linear Trends in the Burden of Metabolic Dysfunction-Associated Steatotic Liver Disease From 1990 to 2021', Liver International, 45, http://dx.doi.org/10.1111/liv.16195

Liu H; Zou M; Shen M; Kamarulzaman A; Chen S; Li J; Li R; Liu H; Zou Z; Zhang L, 2025, 'HPV vaccination is highly effective and cost-effective for cervical cancer prevention in women living with HIV in China: A cost-effectiveness analysis', International Journal of Cancer, 156, pp. 1225 - 1235, http://dx.doi.org/10.1002/ijc.35242

Soe NN; Latt PM; King A; Lee D; Phillips TR; Fairley CK; Zhang L; Ong JJ, 2025, 'What Do People Want from an AI-Assisted Screening App for Sexually Transmitted Infection-Related Anogenital Lesions: A Discrete Choice Experiment', Patient, 18, pp. 131 - 143, http://dx.doi.org/10.1007/s40271-024-00720-8

Zhang Z; Hu C; Shi F; Zhang L; Wang Y; Zhang Y; Zhang X; She J, 2025, 'Low transthyretin is associated with the poor prognosis of colorectal cancer', Frontiers in Oncology, 15, pp. 1397019, http://dx.doi.org/10.3389/fonc.2025.1397019

Wu H; Shi F; Hu C; Zhang L; Qu P; She J, 2025, 'Association between 5-item modified frailty index and clinical outcomes in elderly rectal cancer patients after radical surgery', Scientific Reports, 15, pp. 4262, http://dx.doi.org/10.1038/s41598-025-88726-6

Liu J; Shen M; Zhuang G; Zhang L, 2025, 'Age-Period-Cohort Analysis of Diabetes Incidence and Mortality in China and Globally, 1990–2019', Journal of Diabetes, 17, http://dx.doi.org/10.1111/1753-0407.70051

Dong W; Liu Y; Bai R; Zhang L; Zhou M, 2025, 'The prevalence and associated disability burden of mental disorders in children and adolescents in China: a systematic analysis of data from the Global Burden of Disease Study', Lancet Regional Health Western Pacific, 55, http://dx.doi.org/10.1016/j.lanwpc.2025.101486

Liu Y; She B; Zhao R; Li G; Hu Y; Lu F; Su S; Zhang L, 2025, 'Exploring the diversity of sexual acts in Chinese men who have sex with men and its impacts on the risk of HIV and sexually transmitted infections', Public Health, 238, pp. 37 - 44, http://dx.doi.org/10.1016/j.puhe.2024.11.011

Zhang Y; Deng H; Zu J; Deng Y; Tan J; Yang Z; Jiao Y; Cui X; Zhang L; Ji F; Wang Y, 2025, 'Global spatiotemporal trends and influencing factors of type 2 diabetes mellitus mortality: estimates and predictions from 1990 to 2040', Frontiers in Endocrinology, 16, http://dx.doi.org/10.3389/fendo.2025.1601089

Lu F; She B; Zhao R; Li G; Hu Y; Liu Y; Zhao M; Zhang L, 2025, 'Identifying High-Risk Populations for Sexually Transmitted Infections in Chinese Men Who Have Sex With Men: A Cluster Analysis', Open Forum Infectious Diseases, 12, http://dx.doi.org/10.1093/ofid/ofae754

Yusufu M; Friedman DS; Kang M; Padhye A; Shang X; Zhang L; Shi D; He M, 2025, 'Retinal vascular fingerprints predict incident stroke: findings from the UK Biobank cohort study', Heart, 111, pp. 306 - 313, http://dx.doi.org/10.1136/heartjnl-2024-324705

Bao Y; Liu H; Lu Q; Sun Y; Wang L; Su S; Lu P; Wang M; Ma T; Xie X; Wang W; Wang L; Zhai Y; Lu F; Wei Y; Li R; Ding M; Yan Y; Jia S; Zhang X; Yang J; Zhang L, 2025, 'Sex- and age-specific multimorbidity networks in middle-aged inpatients: A network-based comparative study between China and the United Kingdom', Innovation in Aging, 9, http://dx.doi.org/10.1093/geroni/igaf090

King AJ; Soe NN; Latt PM; Zhang L; Temple-Smith M; Maddaford K; Fairley CK; Chow EPF; Phillips TR, 2025, 'Sexual health service users’ perspectives on artificial intelligence applications for identification of lesions associated with sexually transmissible infections: A qualitative study', Digital Health, 11, http://dx.doi.org/10.1177/20552076251361749

Yang C; Lv M; Li Y; He Y; Zhang S; Zhang G; Lan J; Guo Z; Cheng Y; Yang Y; Sun J; Ma L; Zhang L, 2025, 'The interactions between psychological stress, gut microbiota, and fecal metabolites: A longitudinal multi-omics study in Chinese adolescents', Current Research in Microbial Sciences, 9, http://dx.doi.org/10.1016/j.crmicr.2025.100498

Shu Y; Shi Z; Wang W; Dou L; Zhang L; Wu M, 2025, 'Adverse childhood experiences, childhood socioeconomic status, and subsequent high myopia: Results from six universities in China', Child Abuse & Neglect, 169, pp. 107636, http://dx.doi.org/10.1016/j.chiabu.2025.107636

Zhao X; Zhang L; Zhang X; Liu X; Zhang Y; Liu Y; Tian X; Men X; Lv L; Feng Y; Song J; Xie T; Liu S; Zhang Y, 2025, 'Anti-CD19 chimeric antigen receptor T cell therapy achieved rapid and sustained remission in a patient with systemic lupus erythematosus-associated refractory immune thrombocytopenia.', Clinical and Experimental Rheumatology, 43, pp. 2001 - 2002, http://dx.doi.org/10.55563/clinexprheumatol/pn0yyk

Xue F; Hu Y; Yang R; Sun J; Yang L; Wang X; Yu Z; Zhu T; Zhou H; Zhou Z; Yan Z; Du X; Zheng C; Liu W; Zhou R; Dai J; Yin J; Wang H; Tang LV; Chen S; Cheng H; Zhu M; Wang S; Song Y; Zhang P; Zhang L; Society of Hematology CMAHTCCNOCOBOTAHGC, 2025, 'Chinese guidance for the clinical application of adeno-associated virus vector-based gene therapy for hemophilia B (2025)', Blood Science, 7, pp. e00257, http://dx.doi.org/10.1097/bs9.0000000000000257

Wang M; Zhang L; Novak SW; Yu J; Gallina IS; Xu LL; Lim CK; Fernandes S; Shokhirev MN; Williams AE; Saxena MD; Coorapati S; Parylak SL; Quintero C; Molina E; Andrade LR; Manor U; Gage FH, 2025, 'Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain', Nature Biotechnology, 43, pp. 52 - 62, http://dx.doi.org/10.1038/s41587-024-02157-8

Mesa RA; Gill H; Xiao Z; Komatsu N; Qin A; Tashi T; Zhang L; Jin J; Kirito K; Ohishi K; Shirane S; Shih L-Y; Lee S-E; Teo WZY; Maze D; Oh S; Sato T; Shih W; Mascarenhas J; Masarova L; Group S-ES, 2025, 'Ropeginterferon alfa-2b versus anagrelide for the treatment of essential thrombocythemia: Topline results of the phase 3 SURPASS-ET trial.', Journal of Clinical Oncology, 43, pp. 6500 - 6500, http://dx.doi.org/10.1200/jco.2025.43.16_suppl.6500

Bi J; Mo W; Liu M; Song Y; Xiao Q; Fan S; Wang W; Shi T; Zheng Y; Lian J; Liu R; Chen B; Huang X; Li P; Zhao Z; Shi J; Zhang L; Su G; Zhang N; Lu W, 2025, 'Systematic decoding of functional enhancer connectomes and risk variants in human glioma', Nature Cell Biology, 27, pp. 1838 - 1847, http://dx.doi.org/10.1038/s41556-025-01737-3

Gan C; Leng M; Liu Y; Zheng Z; He S; Qiao W; Xiao L; Xiao Y; Ye J; Zhou L; Zhou J; Xiao B; Zhao W; Yang J; Wu A; Zhang H; Hu H; Cen X; Qian Z; Dong H; Valencia CA; Dai L; Chow HY; Zhang L; Dong B, 2025, 'The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver', Molecular Therapy Advances, 33, pp. 101399, http://dx.doi.org/10.1016/j.omtm.2024.101399

Yang H; Yang Z; Zhang L; Yang Y; Zhou D; Li D; Zhang J; Wang Z, 2025, 'Trans-Driver: A Deep Learning Approach for Cancer Driver Gene Discovery With Multi-Omics Data', IEEE Transactions on Computational Biology and Bioinformatics, 22, pp. 3065 - 3076, http://dx.doi.org/10.1109/tcbbio.2025.3612010

Soe NN; Towns JM; Latt PM; Woodberry O; Chung M; Lee D; Ong JJ; Chow EPF; Zhang L; Fairley CK, 2024, 'Accuracy of symptom checker for the diagnosis of sexually transmitted infections using machine learning and Bayesian network algorithms', BMC Infectious Diseases, 24, http://dx.doi.org/10.1186/s12879-024-10285-4

Mahe J; Xu A; Liu L; Hua L; Tu H; Huo Y; Huang W; Liu X; Wang J; Tang J; Zhao Y; Liu Z; Hong Q; Ye R; Hu P; Jia P; Huang J; Kong X; Ge Z; Xu A; Wu L; Du C; Shi F; Cui H; Wang S; Li Z; Wang L; Zhang L; Zhang L, 2024, 'Association between weekend warrior physical activity pattern and all-cause mortality among adults living with type 2 diabetes: a prospective cohort study from NHANES 2007 to 2018', Diabetology and Metabolic Syndrome, 16, http://dx.doi.org/10.1186/s13098-024-01455-0

Sun J; She B; Latt PM; Ong JJ; Xu X; Bao Y; Fairley CK; Zhang L; Tang W; Zhang L, 2024, 'Comparing the impact of sexualised drug use with and without chemsex on sexual behaviours among men who have sex with men in China: a national multi-site cross-sectional study', Sexual Health, 21, http://dx.doi.org/10.1071/SH24173

Adawiyah RA; Bradshaw CS; Vodstrcil LA; Fairley CK; Zhang L; Ong JJ, 2024, 'Cost-effectiveness of resistance-guided therapy for Mycoplasma genitalium in Australia', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-63056-1

Zhang X; Li D; Ye S; Liu S; Ma S; Li M; Peng Q; Hu L; Shang X; He M; Zhang L, 2024, 'Decoding the genetic comorbidity network of Alzheimer's disease', Biodata Mining, 17, http://dx.doi.org/10.1186/s13040-024-00394-w

Wang Y; Liu C; Hu W; Luo L; Shi D; Zhang J; Yin Q; Zhang L; Han X; He M, 2024, 'Economic evaluation for medical artificial intelligence: accuracy vs. cost-effectiveness in a diabetic retinopathy screening case', Npj Digital Medicine, 7, http://dx.doi.org/10.1038/s41746-024-01032-9

Soe NN; Yu Z; Latt PM; Lee D; Ong JJ; Ge Z; Fairley CK; Zhang L, 2024, 'Evaluation of artificial intelligence-powered screening for sexually transmitted infections-related skin lesions using clinical images and metadata', BMC Medicine, 22, http://dx.doi.org/10.1186/s12916-024-03512-x

Zhang Y; Goh SM; Tapa J; Johnson CC; Chow EPF; Zhang L; Phillips T; Fairley CK; Ong JJ, 2024, 'Linkage to care and prevention after HIV self-testing: a systematic review and meta-analysis', Journal of the International AIDS Society, 27, http://dx.doi.org/10.1002/jia2.26388

Yang S; Liu R; Xin Z; Zhu Z; Chu J; Zhong P; Zhu Z; Shang X; Huang W; Zhang L; He M; Wang W, 2024, 'Plasma Metabolomics Identifies Key Metabolites and Improves Prediction of Diabetic Retinopathy: Development and Validation across Multinational Cohorts', Ophthalmology, 131, pp. 1436 - 1446, http://dx.doi.org/10.1016/j.ophtha.2024.07.004

Latt PM; Soe NN; King AJ; Lee D; Phillips TR; Xu X; Chow EPF; Fairley CK; Zhang L; Ong JJ, 2024, 'Preferences for attributes of an artificial intelligence-based risk assessment tool for HIV and sexually transmitted infections: a discrete choice experiment', BMC Public Health, 24, http://dx.doi.org/10.1186/s12889-024-20688-2

Ye S; Ma S; Liu S; Huang Y; Li D; Li M; Su T; Luo J; Zhang C; Shi D; Hu L; Zhang L; Yu H; He M; Shang X; Zhang X, 2024, 'Shared whole environmental etiology between Alzheimer’s disease and age-related macular degeneration', Npj Aging, 10, http://dx.doi.org/10.1038/s41514-024-00162-4

Li M; Liu S; Ma S; Shang X; Zhang X; Jason H; Huang Y; Kiburg K; Zhao K; Hu G; Zhang L; Yu H; He M; Zhang X, 2024, 'Network-based hub biomarker discovery for glaucoma', BMJ Open Ophthalmology, 9, http://dx.doi.org/10.1136/bmjophth-2024-001915

Fu R; Liu X; Qu X; Xue F; Liu W; Chen Y; Sun T; Ju M; Dong H; Gu W; Dai X; Yang R; Zhang L, 2024, 'A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia', Blood, 144, pp. 5438 - 5438, http://dx.doi.org/10.1182/blood-2024-204932

Feng X; Meng M; Sun Z; Zhang X; Zhang L; Zhang M, 2024, 'Cytokine Patterns for Secondary HLH: Experiences from a Single Center', Blood, 144, pp. 4375 - 4375, http://dx.doi.org/10.1182/blood-2024-207671

Yan Z; Zou D; Qian W; Lu Y; Li Y; Ji D; Zhu X; Mei H; Li P; Qu C; Zhang L; Zhou K; Jing H; Niu T; Ji C; Li L; Yang H; Li F; Wang W; Xu K; Zhao J; Wu D; Hu Y; Zhao W, 2024, 'Efficacy and Safety of Axicabtagene Ciloleucel (Axi-cel) for the Treatment of Relapse/Refractory Non-Hodgkin's Lymphoma: Real-World Data in Chinese Population', Blood, 144, pp. 5115 - 5115, http://dx.doi.org/10.1182/blood-2024-207186

Kuter DJ; Ghanima W; Cooper N; Liebman HA; Zhang L; Hu Y; Miyakawa Y; Morales Galindo LE; Basquiera AL; Tan CW; Saydam G; Hütter-Krönke ML; Chai-Adisaksopha C; Gomez-Almaguer D; Tran H; Shin H-J; Pascual Izquierdo MC; Kirgner I; Lucchini E; Kuzmina G; Audia S; Cordoba M; Diab R; Yao M; Lee MJ; Daak A, 2024, 'Efficacy and Safety of Oral Bruton Tyrosine Kinase Inhibitor (BTKi) Rilzabrutinib in Adults with Previously Treated Immune Thrombocytopenia (ITP): A Phase 3, Placebo-Controlled, Parallel-Group, Multicenter Study (LUNA 3)', Blood, 144, pp. 5 - 5, http://dx.doi.org/10.1182/blood-2024-199718

Zhang J; Chen J; Yang R; Zhang L, 2024, 'Machine Learning Analysis Was Conducted to Construct a Novel Model for Modulating the Clinical Manifestations and Predicting the Response to Glucocorticoids in Immune Thrombocytopenia', Blood, 144, pp. 2570 - 2570, http://dx.doi.org/10.1182/blood-2024-203542

Yang Y; Li H; Liu X; Wang H; Zhang L; Yang R, 2024, 'Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia', Blood, 144, pp. 2553 - 2553, http://dx.doi.org/10.1182/blood-2024-203209

Chen Y; Sun T; Gao D; Wang W; Zhou Z; Gao G; Wang Y; Zhou H; Song Y; Lai Y; Yan Z; Yan J; Bai J; Zhang L, 2024, 'Optimized Recombinant Human Thrombopoietin(rhTPO) Regimen Versus Eltrombopag for Pre-Treated Patients with Primary Immune Thrombocytopenia: Interim Results from a Prospective, Multicenter, Randomized Trial (TE-ITP study)', Blood, 144, pp. 3937 - 3937, http://dx.doi.org/10.1182/blood-2024-202716

Yan J; Wang B; Wei Y; Zhang S; Zhang L; Li L; Li X; Fu X; Wang X; Sun Z; Zhang X; Zhang M, 2024, 'Outcomes and Prognostic Factors of the Alternative Regimens for Angioimmunoblastic T Cell Lymphoma: A Retrospective Study', Blood, 144, pp. 6408 - 6408, http://dx.doi.org/10.1182/blood-2024-206732

Liu W; Pei X; Xu B; Dai X; Xue F; Chen L; Wang Y; Chen Y; Liu X; Fu R; Wang W; Chi Y; Li H; Yang R; Zhang L, 2024, 'Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy', Blood, 144, pp. 3583 - 3583, http://dx.doi.org/10.1182/blood-2024-199915

Zhang X; Fan M; Wang W; Wu J; Ma S; Dong M; Zhu L; Wu X; Feng X; Li X; Li L; Sun Z; Wang X; Fu X; Li Z; Yan J; Chang Y; Yu H; Nan F; Zhou Z; Ding M; Zhang J; Zhang L; Zhang M, 2024, 'Strikingly Reduced Toxicities of Fotemustine-Based Chemotherapeutics Than High-Dose Methotrexate-Containing Regimens with Comparable Efficacy', Blood, 144, pp. 6458 - 6458, http://dx.doi.org/10.1182/blood-2024-202107

Amhare AF; Shen M; Zou Z; Xia R; Han J; Gao L; Zhang L, 2024, 'Assessing the impact of COVID-19 on HIV care cascade for people living with HIV in Ethiopia: a retrospective longitudinal study', BMJ Open, 14, http://dx.doi.org/10.1136/bmjopen-2024-084244

Zou Z; Fairley CK; Ong JJ; Shen M; Chow EPF; Liu H; Xia R; Li R; Hocking J; Zhuang G; Zhang L, 2024, 'Impact of achieving WHO's 90-70-90 targets on cervical cancer elimination and potential benefits in preventing other HPV-related cancers in China: a modelling study', Eclinicalmedicine, 77, http://dx.doi.org/10.1016/j.eclinm.2024.102878

Shen M; Zhang L, 2024, 'The third generation modified vaccinia Ankara vaccine is effective in preventing the transmission of mpox', Lancet Regional Health Europe, 45, http://dx.doi.org/10.1016/j.lanepe.2024.101052

Li H; Liang X; Peng Y; Liu Z; Zhang L; Wang P; Jin M; Wilson K; Garvin MR; Wu K; Xiao Y, 2024, 'Novel Mito-Nuclear Combinations Facilitate the Global Invasion of a Major Agricultural Crop Pest', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202305353

She B; Lu F; Zhao R; Lin S; Sun J; He S; Liu Y; Su S; Zhang L, 2024, 'Examining the Effects of PrEP Use on Sexual Behaviors and Sexually Transmitted Infections Among Chinese Men who have Sex with Men: A Cross-Sectional Study', AIDS and Behavior, 28, pp. 3128 - 3138, http://dx.doi.org/10.1007/s10461-024-04398-9

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