Select Publications
Journal articles
2010, 'c-Jun regulates shear-and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins.', The Journal of Biological Chemistry, 285, pp. 4038 - 4048, http://dx.doi.org/10.1074/jbc.M109.078345
,2010, 'Drug-induced thrombocytopenia (DITP): development of a novel NOD/SCID mouse model to evaluate clearance of circulating platelets by drug-dependent antibodies and the efficacy of IVIG', Blood, 116, pp. 1958 - 1960
,2010, 'Macrophage migration inhibitory factor increases leukocyte-endothelial interactions in human endothelial cells via promotion of expression of adhesion molecules.', Journal of Immunology, 185, pp. 1238 - 1247
,2010, 'PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminologycan elongationon biglycan and increases binding to LDL.', Endocrinology, 151, pp. 4356 - 4367
,2010, 'Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription.', Arteriosclerosis, Thrombosis and Vascular Biology, 30, pp. 536 - 545, http://dx.doi.org/10.1161/ATVBAHA.109.193821
,2010, 'Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway', Haematologica, 95, pp. 1745 - 1753
,2010, 'TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner', Circulation Research, 106, pp. 1061 - 1071
,2009, 'Related transcriptional enhancer factor-1 induces fibroblast growth factor receptor-1 expression in endothelial cells (Retraction of vol 380, pg 689, 2009)', BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 388, pp. 464 - 464, http://dx.doi.org/10.1016/j.bbrc.2009.08.011
,2009, 'C-Jun is critical for the progression of osteosarcoma: Proof in an orthotopic spontaneously metastasizing model (Molecular Cancer Research (2008) 6, (1289-1292))', Molecular Cancer Research, 7, pp. 1594, http://dx.doi.org/10.1158/1541-7786.MCR-07-9-COR2
,2009, 'DNA enzyme targeting transcription factor c-Jun reduces intimal hyperplasia in human saphenous vein explants and inhibits Vein Graft stenosis in rabbits', EUROPEAN HEART JOURNAL, 30, pp. 322 - 322, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208702603073&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'DNAZYME TARGETING TRANSCRIPTION FACTOR C-JUN INHIBITS MYOCARDIAL INFLAMMATION, ROS GENERATION AND INFARCT SIZE AFTER ISCHEMIA-REPERFUSION INJURY', ATHEROSCLEROSIS SUPPLEMENTS, 10, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207957101541&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'PROTECTION AGAINST ATHEROSCLEROSIS BY HEME OXYGENASE-1', ATHEROSCLEROSIS SUPPLEMENTS, 10, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207957100820&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'Immediate-early genes as master regulators in cancer and other vascular disease', INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 24, pp. S77 - S77, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270497500292&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2009, 'A Key Role for Early Growth Response-1 and Nuclear Factor-kappa B in Mediating and Maintaining GRO/CXCR2 Proliferative Signaling in Esophageal Cancer', Molecular Cancer Research, 7, pp. 755 - 764
,2009, 'Abstract: 81 PROTECTION AGAINST ATHEROSCLEROSIS BY HEME OXYGENASE', Atherosclerosis Supplements, 10, pp. e220 - e220, http://dx.doi.org/10.1016/s1567-5688(09)70224-7
,2009, 'Abstract: P668 DNAZYME TARGETING TRANSCRIPTION FACTOR C-JUN INHIBITS MYOCARDIAL INFLAMMATION, ROS GENERATION AND INFARCT SIZE AFTER ISCHEMIA-REPERFUSION INJURY', Atherosclerosis Supplements, 10, pp. e854 - e854, http://dx.doi.org/10.1016/s1567-5688(09)70836-0
,2009, 'Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and fasl-fas engagement', Circulation Research, 105, pp. 422 - 430, http://circres.ahajournals.org/cgi/content/full/105/5/422
,2009, 'c-Jun DNAzymes Inhibit Myocardial Inflammation, ROS Generation, Infarct Size, and Improve Cardiac Function After Ischemia-Reperfusion Injury', Arteriosclerosis, Thrombosis and Vascular Biology, 29, pp. 1836 - U282
,2009, 'c-Jun Induces Intimal Hyperplasia in a Rabbit End-to-Side Autologous Veno-Arterial Transplantation Model', Heart, Lung and Circulation, 18, pp. S110 - S111, http://dx.doi.org/10.1016/j.hlc.2009.05.250
,2009, 'DNAzymes and their therapeutic possibilities', Internal Medicine Journal, 39, pp. 249 - 251
,2009, 'Early growth response-1 regulates angiopoietin-1-induced endothelial cell proliferation, migration, and differentiation', Arteriosclerosis, Thrombosis and Vascular Biology, 29, pp. 209 - 216
,2009, 'Prolonged Diabetes in Rats is Associated With Increased Myocardial Fibrosis and Profound Sensitivity to Ischaemia', Heart, Lung and Circulation, 18, pp. S314 - S314, http://dx.doi.org/10.1016/j.hlc.2009.05.484
,2009, 'Recent advances in vascular biology: Selected highlights from IVBM 2008', Thrombosis and Haemostasis, 101, pp. 997 - 998
,2009, 'Related transcriptional enhancer factor-1 induces fibroblast growth factor receptor-1 expression in endothelial cells', Biochemical and Biophysical Research Communications, 380, pp. 689 - 694
,2009, 'Retraction notice to `Related transcriptional enhancer factor-1 induces fibroblast growth factor receptor-1 expression in endothelial cells` [Biophys. Res. Commun. 380 (3) (2009) 689-694] (DOI:10.1016/j.bbrc.2009.01.151)', Biochemical and Biophysical Research Communications, 388, pp. 464
,2009, 'Selected Egr-1-dependent molecules are increased acutely with acute myocardial infarction', Heart, Lung and Circulation, 18, pp. S253 - S254, http://dx.doi.org/10.1016/j.hlc.2009.05.625
,2009, 'Selective Egr-1 Inhibition Reduces Infarct Size in the Diabetic Rat Heart with Myocardial Ischaemia–Reperfusion Injury', Heart, Lung and Circulation, 18, pp. S315 - S315, http://dx.doi.org/10.1016/j.hlc.2009.05.485
,2009, 'Sp1 phosphorylation and its regulation of gene transcription', Molecular and Cellular Biology, 29, pp. 2483 - 2488
,2008, 'Response to abcouwer and roybal', Circulation Research, 103, http://dx.doi.org/10.1161/CIRCRESAHA.108.187559
,2008, 'Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity', Journal of Microencapsulation, 25, pp. 421 - 425, http://dx.doi.org/10.1080/02652040802033673
,2008, 'Ang II-Inducible PDGF-D Transcription Requires Ser/Thr Residues In The Second Zinc Finger Region of Sp1: Novel Phosphospecific Antibodies Demonstrate that Sp1 is Phosphorylated by SMC Injury', FASEB JOURNAL, 22, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208467808746&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2008, 'Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury', Circulation Research, 103, pp. 378 - 387
,2008, 'Angiotensin II induction of PDGF-C expression is mediated by AT1 receptor-dependent Egr-1 transactivation', Nucleic Acids Research, 36, pp. 1941 - 1951, http://dx.doi.org/10.1093/nar/gkm923
,2008, 'Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific ser/thr residues in the second zinc finger region of Sp1', Circulation Research, 102, pp. E38 - E51, http://dx.doi.org/10.1161/CIRCRESAHA.107.167395
,2008, 'C-Jun is critical for the progression of osteosarcoma: Proof in an orthotopic spontaneously metastasizing model', Molecular Cancer Research, 6, pp. 1289 - 1292
,2008, 'c-Jun knockdown sensitizes osteosarcoma to doxorubicin', Molecular Cancer Therapeutics, 7, pp. 1909 - 1912
,2008, 'DNAzyme technology and cancer therapy: cleave and let die', Molecular Cancer Therapeutics, 7, pp. 243 - 251, http://dx.doi.org/10.1158/1535-7163.MCT-07-0510
,2008, 'DNAzymes and cardiovascular disease', British Journal of Pharmacology, 154, pp. 741 - 748, http://dx.doi.org/10.1038/bjp.2008.145
,2008, 'Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model', Cancer Biology and Therapy, 7, pp. 1033 - 1036
,2008, 'Involvement of c-jun in human liposarcoma growth - Supporting data from clinical immunohistochemistry and DNAzyme efficacy', Cancer Biology and Therapy, 7, pp. 1297 - 1301
,2008, 'Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey', Medical Journal of Australia, 188, pp. 520 - 524
,2008, 'Regulation of Vascular Endothelial Growth Factor A by Activating Transcription Factor 4 Response', Circulation Research, 103, pp. E119 - E119
,2008, 'TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappa B and induction of insulin-like growth factor-1 receptor', The Journal of Biological Chemistry, 283, pp. 7754 - 7762, http://dx.doi.org/10.1074/jbc.M706927200
,2007, 'Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment', Biochemical Journal, 407, pp. 79 - 87, http://dx.doi.org/10.1042/BJ20070380
,2007, 'The transcription factor early growth response gene 1 (Egr-1) is implicated in acute myocardial ischemic reperfusion injury in an in vivo model of diabetes', EUROPEAN HEART JOURNAL, 28, pp. 434 - 434, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208702202289&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2007, 'The streptozotocin-treated Sprague-Dawley rat: A useful model for the assessment of acute and chronic effects of myocardial ischaemia reperfusion injury in experimental diabetes', Diabetes and Vascular Disease Research, 4, pp. 153 - 154, http://dx.doi.org/10.3132/dvdr.2007.035
,2007, 'Brothers in arms - DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies', American Journal of Pathology, 171, pp. 1079 - 1088
,2007, 'Oxidative stress regulates IGF1R expression in vascular smooth muscle cells via p53/TBP promoter interactions', Biochemical Journal, 407, pp. 79 - 87
,2007, 'Science never sleeps: Tucker Collins, MD, PhD', Endothelium - Journal of Endothelial Cell Research, 14, pp. 173 - 174
,2007, 'Suppression of growth factor expression and human vascular smooth muscle cell growth by small interfering RNA targeting EGR-1', Journal of Cellular Biochemistry, 100, pp. 1526 - 1535
,