By Professor Maria Kavallaris

Journal articles

Hassan N; Yi H; Malik B; Gaspard-Boulinc L; Samaraweera SE; Casolari DA; Seneviratne J; Balachandran A; Chew T; Duly A; Carter DR; Cheung BB; Norris M; Haber M; Kavallaris M; Marshall GM; Zhang XD; Liu T; Wang J; Liebermann DA; D'Andrea RJ; Wang JY, 2024, 'Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML', Blood, 144, pp. 84 - 98, http://dx.doi.org/10.1182/blood.2024024072

Forgham H; Zhu J; Huang X; Zhang C; Biggs H; Liu L; Wang YC; Fletcher N; Humphries J; Cowin G; Mardon K; Kavallaris M; Thurecht K; Davis TP; Qiao R, 2024, 'Multifunctional Fluoropolymer-Engineered Magnetic Nanoparticles to Facilitate Blood-Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202401340

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2024, 'Erratum: miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (Molecular Therapy (2022) 30(3) (1119–1134), (S1525001622000041), (10.1016/j.ymthe.2022.01.004))', Molecular Therapy, 32, pp. 2031 - 2033, http://dx.doi.org/10.1016/j.ymthe.2024.05.008

Evans L; Walker R; MacDiarmid J; Brahmbhatt H; Anazodo A; McCowage G; Gifford AJ; Kavallaris M; Trahair T; Ziegler DS, 2024, 'A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor', Targeted Oncology, 19, pp. 333 - 342, http://dx.doi.org/10.1007/s11523-024-01051-2

Poltavets V; Jung M; Skhinas J; Kimpton K; Kamili A; Tax G; Mao J; Cui L; Wong M; Cowley MJ; Lau L; Dolman EME; Gooding JJ; Kavallaris M, 2024, 'Abstract 5475: Development of high-throughput 3D bioprinted pediatric models for precision medicine', Cancer Research, 84, pp. 5475 - 5475, http://dx.doi.org/10.1158/1538-7445.am2024-5475

Logan A; Howard CB; Huda P; Kimpton K; Ma Z; Thurecht KJ; McCarroll JA; Moles E; Kavallaris M, 2024, 'Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma.', Journal of Controlled Release, 367, pp. 806 - 820, http://dx.doi.org/10.1016/j.jconrel.2024.02.007

Joyce P; Allen CJ; Alonso MJ; Ashford M; Bradbury MS; Germain M; Kavallaris M; Langer R; Lammers T; Peracchia MT; Popat A; Prestidge CA; Rijcken CJF; Sarmento B; Schmid RB; Schroeder A; Subramaniam S; Thorn CR; Whitehead KA; Zhao CX; Santos HA, 2024, 'A translational framework to DELIVER nanomedicines to the clinic', Nature Nanotechnology, http://dx.doi.org/10.1038/s41565-024-01754-7

Mohamed SMA; Schofield P; McCalmont H; Moles E; Friedrich KH; Kavallaris M; Christ D; Bayat N; Lock RB, 2024, 'An antibody fragment-decorated liposomal conjugate targets Philadelphia-like acute lymphoblastic leukemia', International Journal of Biological Macromolecules, 254, pp. 127596, http://dx.doi.org/10.1016/j.ijbiomac.2023.127596

Moles E; Chang DW; Mansfeld FM; Duly A; Kimpton K; Logan A; Howard CB; Thurecht KJ; Kavallaris M, 2024, 'EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer', International Journal of Nanomedicine, 19, pp. 3623 - 3639, http://dx.doi.org/10.2147/IJN.S450534

Graber P; Dolman MEM; Jung MS; Kavallaris M, 2024, 'Ex Vivo Modeling of the Tumor Microenvironment to Develop Therapeutic Strategies for Gliomas', Advanced Therapeutics, http://dx.doi.org/10.1002/adtp.202300442

Du EY; Jung MS; Skhinas J; Tolentino MAK; Noy J; Jamshidi N; Houng JL; Tjandra KC; Engel M; Utama R; Tilley RD; Kavallaris M; Gooding JJ, 2023, '3D Bioprintable Hydrogel with Tunable Stiffness for Exploring Cells Encapsulated in Matrices of Differing Stiffnesses', ACS Applied Bio Materials, 6, pp. 4603 - 4612, http://dx.doi.org/10.1021/acsabm.3c00334

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262

Janjua TI; Cao Y; Ahmed-Cox A; Raza A; Moniruzzaman M; Akhter DT; Fletcher NL; Kavallaris M; Thurecht KJ; Popat A, 2023, 'Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma', Journal of Controlled Release, 357, pp. 161 - 174, http://dx.doi.org/10.1016/j.jconrel.2023.03.040

Gonzales-Aloy E; Ahmed-Cox A; Tsoli M; Ziegler DS; Kavallaris M, 2023, 'From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer', Advanced Drug Delivery Reviews, 196, http://dx.doi.org/10.1016/j.addr.2023.114777

Suwannakot P; Nemec S; Peres NG; Du EY; Kilian KA; Gaus K; Kavallaris M; Gooding JJ, 2023, 'Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands', ACS Biomaterials Science and Engineering, 9, pp. 1362 - 1376, http://dx.doi.org/10.1021/acsbiomaterials.2c01252

Brayford S; Duly A; Teo WS; Dwarte T; Gonzales-Aloy E; Ma Z; McVeigh L; Failes TW; Arndt GM; McCarroll JA; Kavallaris M, 2023, 'βIII-tubulin suppression enhances the activity of Amuvatinib to inhibit cell proliferation in c-Met positive non-small cell lung cancer cells', Cancer Medicine, 12, pp. 4455 - 4471, http://dx.doi.org/10.1002/cam4.5128

Nguyen DHT; Utama RH; Tjandra KC; Suwannakot P; Du EY; Kavallaris M; Tilley RD; Gooding JJ, 2023, 'Tuning the Mechanical Properties of Multiarm RAFT-Based Block Copolyelectrolyte Hydrogels via Ionic Cross-Linking for 3D Cell Cultures', Biomacromolecules, 24, pp. 57 - 68, http://dx.doi.org/10.1021/acs.biomac.2c00632

Jung MS; Ghamrawi S; Du EY; Gooding JJ; Kavallaris M, 2022, 'Advances in 3D Bioprinting for Cancer Biology and Precision Medicine: From Matrix Design to Application', Advanced Healthcare Materials, 11, pp. e2200690, http://dx.doi.org/10.1002/adhm.202200690

Cong VT; Houng JL; Kavallaris M; Chen X; Tilley RD; Gooding JJ, 2022, 'How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?', Chemical Society Reviews, 51, pp. 7531 - 7559, http://dx.doi.org/10.1039/d1cs00707f

Muskovic W; Slavich E; Maslen B; Kaczorowski DC; Cursons J; Crampin E; Kavallaris M, 2022, 'High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes', Genome Research, 32, pp. 1463 - 1473, http://dx.doi.org/10.1101/gr.276818.122

Sumer-Bayraktar Z; Fife CM; Byrne FL; Kavallaris M; Packer NH, 2022, 'Membrane glycome is impacted by the cell culturing mode of neuroblastoma cells with differing migration and invasion potential', Glycobiology, 32, pp. 588 - 599, http://dx.doi.org/10.1093/glycob/cwac016

Ma Z; Wong SW; Forgham H; Esser L; Lai M; Leiske MN; Kempe K; Sharbeen G; Youkhana J; Mansfeld F; Quinn JF; Phillips PA; Davis TP; Kavallaris M; McCarroll JA, 2022, 'Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth', Biomaterials, 285, http://dx.doi.org/10.1016/j.biomaterials.2022.121539

Duly AMP; Kao FCL; Teo WS; Kavallaris M, 2022, 'βIII-Tubulin Gene Regulation in Health and Disease', Frontiers in Cell and Developmental Biology, 10, http://dx.doi.org/10.3389/fcell.2022.851542

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004

Parker AL; Teo WS; Brayford S; Moorthi UK; Arumugam S; Ferguson C; Parton RG; McCarroll JA; Kavallaris M, 2022, 'βIII-Tubulin Structural Domains Regulate Mitochondrial Network Architecture in an Isotype-Specific Manner', Cells, 11, http://dx.doi.org/10.3390/cells11050776

Ahmed-Cox A; Macmillan AM; Pandzic E; Whan RM; Kavallaris M, 2022, 'Application of Rapid Fluorescence Lifetime Imaging Microscopy (RapidFLIM) to Examine Dynamics of Nanoparticle Uptake in Live Cells', Cells, 11, http://dx.doi.org/10.3390/cells11040642

Karsa M; Ronca E; Bongers A; Mariana A; Moles E; Failes TW; Arndt GM; Cheung LC; Kotecha RS; Kavallaris M; Haber M; Norris MD; Henderson MJ; Xiao L; Somers K; Moles Meler E, 2022, 'Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia', Frontiers in Oncology, 11, pp. 779859, http://dx.doi.org/10.3389/fonc.2021.779859

Jung MS; Skhinas JN; Du EY; Tolentino MAK; Utama RH; Engel M; Volkerling A; Sexton A; O'Mahony AP; Ribeiro JCC; Gooding JJ; Kavallaris M, 2022, 'A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability', Biomaterials Science, 10, pp. 5876 - 5887, http://dx.doi.org/10.1039/d2bm00651k

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682

Ahmed-Cox A; Pandzic E; Johnston ST; Heu C; McGhee J; Mansfeld FM; Crampin EJ; Davis TP; Whan RM; Kavallaris M, 2022, 'Spatio-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density', Journal of Controlled Release, 341, pp. 661 - 675, http://dx.doi.org/10.1016/j.jconrel.2021.12.014

Mohamed SMA; Wohlmann A; Schofield P; Sia KCS; McCalmont H; Savvides SN; Verstraete K; Kavallaris M; Christ D; Friedrich KH; Bayat N; Lock RB, 2021, 'A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia', International Journal of Biological Macromolecules, 190, pp. 214 - 223, http://dx.doi.org/10.1016/j.ijbiomac.2021.08.194

Janjua TI; Ahmed-Cox A; Meka AK; Mansfeld FM; Forgham H; Ignacio RMC; Cao Y; McCarroll JA; Mazzieri R; Kavallaris M; Popat A, 2021, 'Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma', Nanoscale, 13, pp. 16909 - 16922, http://dx.doi.org/10.1039/d1nr03553c

Connerty P; Moles E; de Bock CE; Jayatilleke N; Smith JL; Meshinchi S; Mayoh C; Kavallaris M; Lock RB; Moles Meler E, 2021, 'Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for t(8;21) pediatric acute myeloid leukemia', Pharmaceutics, 13, pp. 1681, http://dx.doi.org/10.3390/pharmaceutics13101681

Utama RH; Tan VTG; Tjandra KC; Sexton A; Nguyen DHT; O'Mahony AP; Du EY; Tian P; Ribeiro JCC; Kavallaris M; Gooding JJ, 2021, 'A Covalently Crosslinked Ink for Multimaterials Drop-on-Demand 3D Bioprinting of 3D Cell Cultures', Macromolecular Bioscience, 21, pp. e2100125, http://dx.doi.org/10.1002/mabi.202100125

Conte C; Monteiro PF; Gurnani P; Stolnik S; Ungaro F; Quaglia F; Clarke P; Grabowska A; Kavallaris M; Alexander C, 2021, 'Multi-component bioresponsive nanoparticles for synchronous delivery of docetaxel and TUBB3 siRNA to lung cancer cells', Nanoscale, 13, pp. 11414 - 11426, http://dx.doi.org/10.1039/d1nr02179f

Janjua TI; Rewatkar P; Ahmed-Cox A; Saeed I; Mansfeld FM; Kulshreshtha R; Kumeria T; Ziegler DS; Kavallaris M; Mazzieri R; Popat A, 2021, 'Frontiers in the treatment of glioblastoma: Past, present and emerging', Advanced Drug Delivery Reviews, 171, pp. 108 - 138, http://dx.doi.org/10.1016/j.addr.2021.01.012

Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278

Grohmann C; Walker F; Devlin M; Luo MX; Chüeh AC; Doherty J; Vaillant F; Ho GY; Wakefield MJ; Weeden CE; Kamili A; Murray J; Po’uha ST; Weinstock J; Kane SR; Faux MC; Broekhuizen E; Zheng Y; Shield-Artin K; Kershaw NJ; Tan CW; Witchard HM; Ebert G; Charman SA; Street I; Kavallaris M; Haber M; Fletcher JI; Asselin-Labat ML; Scott CL; Visvader JE; Lindeman GJ; Watson KG; Burgess AW; Lessene G, 2021, 'Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors', Cell Death and Disease, 12, pp. 268, http://dx.doi.org/10.1038/s41419-020-03269-0

Yang Y; Mansfeld FM; Kavallaris M; Gaus K; Tilley RD; Gooding JJ, 2021, 'Monitoring the heterogeneity in single cell responses to drugs using electrochemical impedance and electrochemical noise', Chemical Science, 12, pp. 2558 - 2566, http://dx.doi.org/10.1039/d0sc05489e

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Srivastava P; Potas JR; Hung T; Power C; Hardy P; Ma DD; Kilian KA; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE; Subramanian S, 2021, 'Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine', Science Advances, 7, pp. eabd1929, http://dx.doi.org/10.1126/sciadv.abd1929

Utama RH; Tan VTG; Tjandra KC; Sexton A; Nguyen DHT; O’Mahony AP; Ribeiro JCC; Kavallaris M; Gooding JJ, 2021, 'A covalently crosslinked bioink for multi-materials drop-on-demand 3D bioprinting of three-dimensional cell cultures', , pp. 2021.02.18.431759, http://dx.doi.org/10.1101/2021.02.18.431759

Muskovic W; Slavich E; Maslen B; Kaczorowski D; Cursons J; Crampin E; Kavallaris M, 2021, 'High temporal resolution RNA-seq time course data reveals mammalian lncRNA activation mirrors neighbouring protein-coding genes', , http://dx.doi.org/10.1101/2021.08.25.457323

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Hung T; Power C; Hardy P; D D; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE; Chacon Fajardo D, 2021, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', Science Advances, pp. 2020.06.04.130872 - 2020.06.04.130872, http://dx.doi.org/10.1126/sciadv.abd1929

Utama RH; Atapattu L; O'Mahony AP; Fife CM; Baek J; Allard T; O'Mahony KJ; Ribeiro JCC; Gaus K; Kavallaris M; Gooding JJ, 2020, 'A 3D Bioprinter Specifically Designed for the High-Throughput Production of Matrix-Embedded Multicellular Spheroids', iScience, 23, pp. 101621, http://dx.doi.org/10.1016/j.isci.2020.101621

Voli F; Valli E; Lerra L; Kimpton K; Saletta F; Giorgi FM; Mercatelli D; Rouaen JRC; Shen S; Murray JE; Ahmed-Cox A; Cirillo G; Mayoh C; Beavis PA; Haber M; Trapani JA; Kavallaris M; Vittorio O, 2020, 'Intratumoral copper modulates PD-L1 expression and influences tumor immune evasion', Cancer Research, 80, pp. 4129 - 4144, http://dx.doi.org/10.1158/0008-5472.CAN-20-0471

Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014

Tjandra KC; Forest CR; Wong CK; Alcantara S; Kelly HG; Ju Y; Stenzel MH; McCarroll JA; Kavallaris M; Caruso F; Kent SJ; Thordarson P, 2020, 'Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display', Advanced Healthcare Materials, 9, http://dx.doi.org/10.1002/adhm.202000261

Keenan B; Finol-Urdaneta RK; Hope A; Bremner JB; Kavallaris M; Lucena-Agell D; Oliva MA; Diaz JF; Vine KL, 2020, 'N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity', CANCER CELL INTERNATIONAL, 20, http://dx.doi.org/10.1186/s12935-020-01251-6

Vittorio O; Kamili A; Valli E; Kavallaris M; LE GRAND M, 2020, 'Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation', Theranostics, 10, pp. 6411 - 6429, http://dx.doi.org/10.7150/thno.42602

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