By Professor Maria Kavallaris

Journal articles

Tjandra KC; McCarthy N; Yang L; Laos AJ; Sharbeen G; Phillips PA; Forgham H; Sagnella SM; Whan RM; Kavallaris M; Thordarson P; McCarroll JA, 2020, 'Identification of Novel Medulloblastoma Cell-Targeting Peptides for Use in Selective Chemotherapy Drug Delivery', Journal of Medicinal Chemistry, 63, pp. 2181 - 2193, http://dx.doi.org/10.1021/acs.jmedchem.9b00851

Le Grand M; Kimpton K; Gana CC; Valli E; Fletcher JI; Kavallaris M, 2020, 'Targeting Functional Activity of AKT Has Efficacy against Aggressive Neuroblastoma', ACS Pharmacology and Translational Science, 3, pp. 148 - 160, http://dx.doi.org/10.1021/acsptsci.9b00085

Po’uha ST; Le Grand M; Brandl MB; Gifford AJ; Goodall GJ; Khew-Goodall Y; Kavallaris M, 2020, 'Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration', British Journal of Cancer, 122, pp. 434 - 444, http://dx.doi.org/10.1038/s41416-019-0669-1

Utama RH; Atapattu L; O’Mahony AP; Fife CM; Baek J; Allard T; O’Mahony KJ; Ribeiro J; Gaus K; Kavallaris M; Gooding JJ, 2020, 'Precise, high-throughput production of multicellular spheroids with a bespoke 3D bioprinter', , pp. 2020.04.06.028548, http://dx.doi.org/10.1101/2020.04.06.028548

Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5

Xie W; Guo Z; Cao Z; Gao Q; Wang D; Boyer C; Kavallaris M; Sun X; Wang X; Zhao L; Gu Z, 2019, 'Manganese-Based Magnetic Layered Double Hydroxide Nanoparticle: A pH-Sensitive and Concurrently Enhanced T1/ T2-Weighted Dual-Mode Magnetic Resonance Imaging Contrast Agent', ACS Biomaterials Science and Engineering, 5, pp. 2555 - 2562, http://dx.doi.org/10.1021/acsbiomaterials.8b01618

Moles E; Kavallaris M, 2019, 'A potent targeted cancer nanotherapeutic', Nature Biomedical Engineering, 3, pp. 248 - 250, http://dx.doi.org/10.1038/s41551-019-0390-7

Moles E; Kavallaris M; Fernàndez-Busquets X, 2019, 'Modeling the distribution of diprotic basic drugs in liposomal systems: Perspectives on malaria nanotherapy', Frontiers in Pharmacology, 10, http://dx.doi.org/10.3389/fphar.2019.01064

Bayat N; McOrist N; Ariotti N; Lai M; Sia KCS; Li Y; Grace JL; Quinn JF; Whittaker MR; Kavallaris M; Davis TP; Lock RB, 2019, 'Thiol-reactive star polymers functionalized with short ethoxy-containing moieties exhibit enhanced uptake in acute lymphoblastic leukemia cells', International Journal of Nanomedicine, 14, pp. 9795 - 9808, http://dx.doi.org/10.2147/IJN.S220326

Cirillo G; Peitzsch C; Vittorio O; Curcio M; Farfalla A; Voli F; Dubrovska A; Iemma F; Kavallaris M; Hampel S, 2019, 'When polymers meet carbon nanostructures: Expanding horizons in cancer therapy', Future Medicinal Chemistry, 11, pp. 2205 - 2231, http://dx.doi.org/10.4155/fmc-2018-0540

Parker SG; Yang Y; Ciampi S; Gupta B; Kimpton K; Mansfeld FM; Kavallaris M; Gaus K; Justin Gooding J; Gooding J, 2018, 'A photoelectrochemical platform for the capture and release of rare single cells', Nature Communications, 9, pp. 2288, http://dx.doi.org/10.1038/s41467-018-04701-y

Tavallaie R; McCarroll J; Le Grand M; Ariotti N; Schuhmann W; Bakker E; Tilley RD; Hibbert DB; Kavallaris M; Gooding JJ; Hibbert B, 2018, 'Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood', Nature Nanotechnology, 13, pp. 1066 - 1071, http://dx.doi.org/10.1038/s41565-018-0232-x

Faria M; Björnmalm M; Thurecht KJ; Kent SJ; Parton RG; Kavallaris M; Johnston APR; Gooding JJ; Corrie SR; Boyd BJ; Thordarson P; Whittaker AK; Stevens MM; Prestidge CA; Porter CJH; Parak WJ; Davis TP; Crampin EJ; Caruso F, 2018, 'Minimum information reporting in bio–nano experimental literature', Nature Nanotechnology, 13, pp. 777 - 785, http://dx.doi.org/10.1038/s41565-018-0246-4

Chang D; Lim M; Goos JACM; Qiao R; Ng YY; Mansfeld FM; Jackson M; Davis TP; Kavallaris M, 2018, 'Biologically targeted magnetic hyperthermia: Potential and limitations', Frontiers in Pharmacology, 9, pp. 831, http://dx.doi.org/10.3389/fphar.2018.00831

Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738

Oliver S; Yee E; Kavallaris M; Vittorio O; Boyer C, 2018, 'Water Soluble Antioxidant Dextran–Quercetin Conjugate with Potential Anticancer Properties', Macromolecular Bioscience, 18, http://dx.doi.org/10.1002/mabi.201700239

Levrier C; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Sadowski MC; Nelson CC, 2018, 'Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells', Cell Cycle, 17, pp. 652 - 668, http://dx.doi.org/10.1080/15384101.2017.1356512

Parmar A; Pascali G; Voli F; Lerra L; Yee E; Ahmed-Cox A; Kimpton K; Cirillo G; Arthur A; Zahra D; Rahardjo G; Liu GJ; Lengkeek N; Saletta F; Charil A; Kavallaris M; Vittorio O, 2018, 'In vivo [64Cu]CuCl2 PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis', Theranostics, 8, pp. 5645 - 5659, http://dx.doi.org/10.7150/thno.29840

Parker AL; Teo WS; Pandzic E; Vicente JJ; McCarroll JA; Wordeman L; Kavallaris M, 2018, 'β-Tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells', Life Science Alliance, 1, http://dx.doi.org/10.26508/lsa.201800059

Voli F; Lerra L; Kimpton K; Saletta F; Cirillo G; Kavallaris M; Vittorio O, 2018, 'Harnessing copper in cancer to enhance anti-tumor immune response', Annals of Oncology, 29, pp. x35 - x35, http://dx.doi.org/10.1093/annonc/mdy487.030

Oliver S; Jofri A; Thomas DS; Vittorio O; Kavallaris M; Boyer C, 2017, 'Tuneable catechin functionalisation of carbohydrate polymers', Carbohydrate Polymers, 169, pp. 480 - 494, http://dx.doi.org/10.1016/j.carbpol.2017.04.032

Parker AL; Teo WS; McCarroll JA; Kavallaris M, 2017, 'An emerging role for tubulin isotypes in modulating cancer biology and chemotherapy resistance', International Journal of Molecular Sciences, 18, pp. 1434, http://dx.doi.org/10.3390/ijms18071434

Lovelace MD; Powter EE; Coleman PR; Zhao Y; Parker A; Chang GH; Lay AJ; Hunter J; McGrath AP; Jormakka M; Bertolino P; McCaughan G; Kavallaris M; Vadas MA; Gamble JR, 2017, 'The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells', Molecular Biology of the Cell, 28, pp. 1066 - 1078, http://dx.doi.org/10.1091/mbc.E16-05-0285

Wojciechowski JP; Martin AD; Mason AF; Fife CM; Sagnella SM; Kavallaris M; Thordarson P, 2017, 'Choice of Capping Group in Tripeptide Hydrogels Influences Viability in the Three-Dimensional Cell Culture of Tumor Spheroids', ChemPlusChem, 82, pp. 383 - 389, http://dx.doi.org/10.1002/cplu.201600464

Kunz-Schughart LA; Dubrovska A; Peitzsch C; Ewe A; Aigner A; Schellenburg S; Muders MH; Hampel S; Cirillo G; Iemma F; Tietze R; Alexiou C; Stephan H; Zarschler K; Vittorio O; Kavallaris M; Parak WJ; Mädler L; Pokhrel S, 2017, 'Nanoparticles for radiooncology: Mission, vision, challenges', Biomaterials, 120, pp. 155 - 184, http://dx.doi.org/10.1016/j.biomaterials.2016.12.010

Fife CM; Sagnella SM; Teo WS; Po'uha ST; Byrne FL; Yeap YY; Ng DC; Davis TP; McCarroll JA; Kavallaris M, 2017, 'Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration.', Oncogene, 36, pp. 501 - 511, http://dx.doi.org/10.1038/onc.2016.220

Fife CM; McCarroll JA; Kavallaris M, 2017, 'Movers and shakers: cell cytoskeleton in cancer metastasis (vol 171, pg 5507, 2014)', BRITISH JOURNAL OF PHARMACOLOGY, 174, pp. 116 - 116, http://dx.doi.org/10.1111/bph.13672

Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC, 2016, '6α-Acetoxyanopterine: A novel structure class of mitotic inhibitor disrupting microtubule dynamics in prostate cancer cells', Molecular Cancer Therapeutics, 16, pp. 3 - 15, http://dx.doi.org/10.1158/1535-7163.MCT-16-0325

Parker AL; Turner N; McCarroll JA; Kavallaris M, 2016, 'βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells', Carcinogenesis, 37, pp. 787 - 798, http://dx.doi.org/10.1093/carcin/bgw058

Vittorio O; Cojoc M; Curcio M; Spizzirri UG; Hampel S; Nicoletta FP; Iemma F; Dubrovska A; Kavallaris M; Cirillo G, 2016, 'Polyphenol Conjugates by Immobilized Laccase: The Green Synthesis of Dextran-Catechin', Macromolecular Chemistry and Physics, 217, pp. 1488 - 1492, http://dx.doi.org/10.1002/macp.201600046

Pasquier E; André N; Street J; Chougule A; Rekhi B; Ghosh J; Philip DSJ; Meurer M; MacKenzie KL; Kavallaris M; Banavali SD, 2016, 'Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study', EBioMedicine, 6, pp. 87 - 95, http://dx.doi.org/10.1016/j.ebiom.2016.02.026

Ercole F; Mansfeld FM; Kavallaris M; Whittaker MR; Quinn JF; Halls ML; Davis TP, 2016, 'Macromolecular Hydrogen Sulfide Donors Trigger Spatiotemporally Confined Changes in Cell Signaling', Biomacromolecules, 17, pp. 371 - 383, http://dx.doi.org/10.1021/acs.biomac.5b01469

Byrne FL; McCarroll JA; Kavallaris M, 2016, 'Analyses of tumor burden in vivo and metastasis ex vivo using luciferase-expressing cancer cells in an orthotopic mouse model of neuroblastoma', RNA imaging: methods and protocols, 1372, pp. 61 - 77, http://dx.doi.org/10.1007/978-1-4939-3148-4_5

Sharbeen G; McCarroll J; Liu J; Youkhana J; Limbri LF; Biankin AV; Johns A; Kavallaris M; Goldstein D; Phillips PA, 2016, 'Delineating the Role of βIV-Tubulins in Pancreatic Cancer: βIVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids', Neoplasia (United States), 18, pp. 753 - 764, http://dx.doi.org/10.1016/j.neo.2016.10.011

Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

McCarroll JA; Teo J; Boyer C; Youkhana J; Sagnella S; Duong H; Sharbeen G; Goldstein D; Davis T; Kavallaris M; Phillips P; Liu J, 2016, 'A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo.', Biomacromolecules, 17, pp. 2337 - 2351, http://dx.doi.org/10.1021/acs.biomac.6b00185

Oliver S; Thomas DS; Kavallaris M; Vittorio O; Boyer C, 2016, 'Efficient functionalisation of dextran-aldehyde with catechin: potential applications in the treatment of cancer', Polymer Chemistry, http://dx.doi.org/10.1039/C6PY00228E

McCarroll JA; Teo W; Kavallaris M; Byrne F; Davis T, 2016, 'Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration', Oncogene, 36, pp. 501 - 511, http://dx.doi.org/10.1038/onc.2016.220.

Kavallaris M; Po'uha S, 2015, 'Gamma-actin is involved in regulating centrosome function and mitotic progression in cancer cells', Cell Cycle, http://dx.doi.org/10.1080/15384101.2015.1120920

Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005

Makharza S; Vittorio O; Cirillo G; Oswald S; Hinde E; Kavallaris M; Büchner B; Mertig M; Hampel S, 2015, 'Graphene oxide - Gelatin nanohybrids as functional tools for enhanced carboplatin activity in neuroblastoma cells', Pharmaceutical Research, 32, pp. 2132 - 2143, http://dx.doi.org/10.1007/s11095-014-1604-z

Sevimli S; Sagnella S; Macmillan A; Whan R; Kavallaris M; Bulmus V; Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e

McCarroll JA; Gan PP; Erlich RB; Liu M; Dwarte T; Sagnella SS; Akerfeldt MC; Yang L; Parker AL; Chang MH; Shum MS; Byrne FL; Kavallaris M; Sagnella S, 2015, 'TUBB3/βIII-tubulin acts through the PTEN/AKT signaling axis to promote tumorigenesis and anoikis resistance in non-small cell lung cancer', Cancer Research, 75, pp. 415 - 425, http://dx.doi.org/10.1158/0008-5472.CAN-14-2740

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2015, 'Erratum: Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression (Journal of the National Cancer Institute (2014) 106:7 (dju113) DOI: 10.1093/jnci/dju113)', Journal of the National Cancer Institute, 107, http://dx.doi.org/10.1093/jnci/dju359

McCarroll JA; Dwarte T; Baigude H; Dang J; Yang L; Erlich RB; Kimpton K; Teo J; Sagnella SM; Akerfeldt MC; Liu J; Phillips PA; Rana TM; Kavallaris M, 2015, 'Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer', Oncotarget, 6, pp. 12020 - 12034, http://dx.doi.org/10.18632/oncotarget.2664

McCarroll JA; Sharbeen G; Liu J; Youkhana J; Goldstein D; McCarthy N; Limbri LF; Dischl D; Ceyhan GO; Erkan M; Johns AL; Biankin AV; Kavallaris M; Phillips PA; Johns A, 2015, 'βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer', Oncotarget, 6, pp. 2235 - 2249, http://dx.doi.org/10.18632/oncotarget.2946

Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, 7, http://dx.doi.org/10.1186/s13221-014-0027-2

Brandl MB; Pasquier E; Li F; Beck D; Zhang S; Zhao H; Kavallaris M; Wong STC, 2014, 'Computational analysis of image-based drug profiling predicts synergistic drug combinations: Applications in triple-negative breast cancer', Molecular Oncology, 8, pp. 1548 - 1560, http://dx.doi.org/10.1016/j.molonc.2014.06.007

Chen X; Soeriyadi AH; Lu X; Sagnella SM; Kavallaris M; Gooding JJ, 2014, 'Dual bioresponsive mesoporous silica nanocarrier as an "AND" logic gate for targeted drug delivery cancer cells', Advanced Functional Materials, 24, pp. 6999 - 7006, http://dx.doi.org/10.1002/adfm.201402339

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