By Professor Mark Parsons

Journal articles

Bivard A; Spratt N; Levi CR; Parsons MW, 2011, 'Acute stroke thrombolysis: Time to dispense with the clock and move to tissue-based decision making?', Expert Review of Cardiovascular Therapy, 9, pp. 451 - 461, http://dx.doi.org/10.1586/erc.11.7

Gerstein HC; Miller ME; Genuth S; Ismail-Beigi F; Buse JB; Goff DC; Probstfield JL; Cushman WC; Ginsberg HN; Bigger JT; Grimm RH; Byington RP; Rosenberg YD; Friedewald WT, 2011, 'Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes', NEW ENGLAND JOURNAL OF MEDICINE, 364, pp. 818 - 828, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287928400007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Simpson MA; Dewey HM; Parsons MW, 2011, 'In reply', Medical Journal of Australia, 194, pp. 212 - 213, http://dx.doi.org/10.5694/j.1326-5377.2011.tb03788.x

Bivard A; McElduff P; Spratt N; Levi C; Parsons M, 2011, 'Defining the extent of irreversible brain ischemia using perfusion computed tomography', Cerebrovascular Diseases, 31, pp. 238 - 245, http://dx.doi.org/10.1159/000321897

Parsons MW, 2011, 'Treating as early as possible with thrombolysis is crucial, but can we do better in the sub-4.5-hour time window?', Cerebrovascular Diseases, 31, pp. 229, http://dx.doi.org/10.1159/000322555

Nagakane Y; Christensen S; Brekenfeld C; Ma H; Churilov L; Parsons MW; Levi CR; Butcher KS; Peeters A; Barber PA; Bladin CF; De Silva DA; Fink J; Kimber TE; Schultz DW; Muir KW; Tress BM; Desmond PM; Davis SM; Donnan GA, 2011, 'EPITHET: Positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration', Stroke, 42, pp. 59 - 64, http://dx.doi.org/10.1161/STROKEAHA.110.580464

Bivard A; Spratt N; Levi C; Parsons M, 2011, 'Perfusion computer tomography: Imaging and clinical validation in acute ischaemic stroke', Brain, 134, pp. 3408 - 3416, http://dx.doi.org/10.1093/brain/awr257

Garnett AR; Marsden DL; Parsons MW; Quain DA; Spratt NJ; Loudfoot AR; Middleton PM; Levi CR, 2010, 'The rural Prehospital Acute Stroke Triage (PAST) trial protocol: A controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre', International Journal of Stroke, 5, pp. 506 - 513, http://dx.doi.org/10.1111/j.1747-4949.2010.00522.x

Arima H; Anderson CS; Wang JG; Huang Y; Heeley E; Neal B; Woodward M; Skulina C; Parsons MW; Peng B; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J, 2010, 'Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage', Hypertension, 56, pp. 852 - 858, http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154328

Marsden DL; Spratt NJ; Walker R; Barker D; Attia J; Pollack M; Parsons MW; Levi CR, 2010, 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30, pp. 500 - 507, http://dx.doi.org/10.1159/000319022

Chemmanam T; Campbell BCV; Christensen S; Nagakane Y; Desmond PM; Bladin CF; Parsons MW; Levi CR; Barber PA; Donnan GA; Davis SM, 2010, 'Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch', Neurology, 75, pp. 1040 - 1047, http://dx.doi.org/10.1212/WNL.0b013e3181f39ab6

Ahmed N; Wahlgren N; Grond M; Hennerici M; Lees KR; Mikulik R; Parsons M; Roine RO; Toni D; Ringleb P, 2010, 'Implementation and outcome of thrombolysis with alteplase 3-4·5 h after an acute stroke: an updated analysis from SITS-ISTR', The Lancet Neurology, 9, pp. 866 - 874, http://dx.doi.org/10.1016/S1474-4422(10)70165-4

Tu HTH; Campbell BCV; Christensen S; Collins M; De Silva DA; Butcher KS; Parsons MW; Desmond PM; Barber PA; Levi CR; Bladin CF; Donnan GA; Davis SM, 2010, 'Pathophysiological determinants of worse stroke outcome in atrial fibrillation', Cerebrovascular Diseases, 30, pp. 389 - 395, http://dx.doi.org/10.1159/000316886

Pickering RL; Hubbard IJ; Baker KG; Parsons MW, 2010, 'Assessment of the upper limb in acute stroke: The validity of hierarchal scoring for the Motor Assessment Scale', Australian Occupational Therapy Journal, 57, pp. 174 - 182, http://dx.doi.org/10.1111/j.1440-1630.2009.00810.x

Parsons MW; Christensen S; McElduff P; Levi CR; Butcher KS; De Silva DA; Ebinger M; Barber PA; Bladin C; Donnan GA; Davis SM, 2010, 'Pretreatment diffusion-and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis', Journal of Cerebral Blood Flow and Metabolism, 30, pp. 1214 - 1225, http://dx.doi.org/10.1038/jcbfm.2010.3

Lees KR; Bluhmki E; von Kummer R; Brott TG; Toni D; Grotta JC; Albers GW; Kaste M; Marler JR; Hamilton SA; Tilley BC; Davis SM; Donnan GA; Hacke W; Ninds EA, 2010, 'Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials', LANCET, 375, pp. 1695 - 1703, http://dx.doi.org/10.1016/S0140-6736(10)60491-6

Johnston KC; Parsons M, 2010, 'Aggressive glucose control in acute stroke is the answer in the imaging?', Annals of Neurology, 67, pp. 557 - 558, http://dx.doi.org/10.1002/ana.22046

Parsons MW, 2010, 'Commentary: Echocardiography in the detection of cardioembolism in a stroke population', Journal of Clinical Neuroscience, 17, pp. 566, http://dx.doi.org/10.1016/j.jocn.2010.01.001

Campbell BCV; Christensen S; Foster SJ; Desmond PM; Parsons MW; Butcher KS; Barber PA; Levi CR; Bladin CF; Donnan GA; Davis SM, 2010, 'Visual assessment of perfusion-diffusion mismatch is inadequate to select patients for thrombolysis for the epithet investigators', Cerebrovascular Diseases, 29, pp. 592 - 596, http://dx.doi.org/10.1159/000311080

Parsons M, 2010, 'Portable computed tomography scanners in community hospitals: Are they necessary?', International Journal of Stroke, 5, pp. 67 - 67, http://dx.doi.org/10.1111/j.1747-4949.2010.00407.x

Delcourt C; Huang Y; Wang J; Heeley E; Lindley R; Stapf C; Tzourio C; Arima H; Parsons M; Sun J; Neal B; Chalmers J; Anderson C, 2010, 'The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2)', International Journal of Stroke, 5, pp. 110 - 116, http://dx.doi.org/10.1111/j.1747-4949.2010.00415.x

Anderson CS; Huang Y; Arima H; Heeley E; Skulina C; Parsons MW; Peng B; Li Q; Su S; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J; Wang JG, 2010, 'Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: The intensive blood pressure reduction in acute cérébral haemorrhage trial (INTERACT)', Stroke, 41, pp. 307 - 312, http://dx.doi.org/10.1161/STROKEAHA.109.561795

De Silva DA; Brekenfeld C; Ebinger M; Christensen S; Barber PA; Butcher KS; Levi CR; Parsons MW; Bladin CF; Donnan GA; Davis SM, 2010, 'The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the echoplanar imaging thrombolytic evaluation trial (EPITHET)', Stroke, 41, pp. 295 - 299, http://dx.doi.org/10.1161/STROKEAHA.109.562827

Hankey GJ; Eikelboom JW; Baker RI; Gelavis A; Hickling SC; Jamrozik K; van Bockxmeer FM; Vasikaran S; Chen C; Lees KR; Yi Q; Algra A; Wong MC; Cheung R; Wong L; Divjak I; Ferro J; de Freitas G; Gommans J; Groppa S; Hill M; Spence JD; Lisheng L; Navarro J; Ranawaka U; Ricci S; Schmidt R; Slivka A; Tan K; Tsiskaridze A; Uddin W; Vanhooren G; Xavier D; Armitage J; Hobbs M; Le M; Sudlow C; Wheatley K; Yi Q; Brown W; Bulder M; Ho WK; Klijn CJM; Koedam E; Langton P; Nijboer E; Tuch P; Pizzi J; Tang M; Alaparthi R; Antenucci M; Chew Y; Chinnery D; Cockayne C; Holt R; Loh K; McMullin L; Mulholland G; Nahoo B; Read E; Smith F; Yip CY; Crimmins D; Davis T; England M; Rakic V; Schultz DW; Frayne J; Bladin C; Kokkinos J; Dunbabin D; Harper J; Rees P; Warden D; Levi C; Parsons M; Russell M; Spratt N; Clayton P; Nayagam P; Sharp J; Grainger K; de Wytt C; McDougall A; Donnan GA; Grimley R; Neynens E; Reinhart B; Ropele S; Stögerer E; Dedeken P; Schelstraete C; Veyt A; Andre C; de Freitas GR; Gomes SE; Mok VCT; Wong A; Wong LKS, 2010, 'B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins to prevent stroke (VITATOPS) trial: A randomised, double-blind, parallel, placebo-controlled trial', The Lancet Neurology, 9, pp. 855 - 865, http://dx.doi.org/10.1016/S1474-4422(10)70187-3

Butcher K; Christensen S; Parsons M; De Silva DA; Ebinger M; Levi C; Jeerakathil T; Campbell BCV; Barber PA; Bladin C; Fink J; Tress B; Donnan GA; Davis SM, 2010, 'Postthrombolysis blood pressure elevation is associated with hemorrhagic transformation', Stroke, 41, pp. 72 - 77, http://dx.doi.org/10.1161/STROKEAHA.109.563767

Campbell BCV; Christensen S; Butcher KS; Gordon I; Parsons MW; Desmond PM; Barber PA; Levi CR; Bladin CF; De Silva DA; Donnan GA; Davis SM, 2010, 'Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke', Stroke, 41, pp. 82 - 88, http://dx.doi.org/10.1161/STROKEAHA.109.562116

Campbell BCV; Christensen S; Desmond PM; Parsons MW; Barber PA; De Silva DA; Levi CR; Bladin C; Donnan GA; Davis SM, 2010, '3. Major infarct growth beyond 3–6hours is associated with failure of collateral circulation', Journal of Clinical Neuroscience, 17, pp. 1610 - 1611, http://dx.doi.org/10.1016/j.jocn.2010.07.004

Spratt NJ; McLeod D; Levi CR; Beautement S; Buxton D; Abel C; Calford M; Parsons M, 2010, '4. Penumbral imaging with computed tomography perfusion in an experimental model of acute stroke', Journal of Clinical Neuroscience, 17, pp. 1611 - 1611, http://dx.doi.org/10.1016/j.jocn.2010.07.005

Campbell BCV; Costello C; Christensen S; Ebinger M; Parsons MW; Desmond P; Barber PA; Butcher KS; Levi CR; De Silva DA; Lansberg MG; Mlynash M; Olivot J-M; Straka M; Bammer R; Albers GW; Donnan GA; Davis SM; Spratt NJ, 2010, '67. FLAIR hyperintensity in acute ischemic strokes beyond 3hours is almost universal and does not predict hemorrhagic transformation', Journal of Clinical Neuroscience, 17, pp. 1630 - 1630, http://dx.doi.org/10.1016/j.jocn.2010.07.068

Campbell BCV; Christensen S; Tu H; Desmond PM; Levi CR; Bladin C; Hjort N; Ashkanian M; Solling C; Donnan GA; Davis SM; Ostergaard L; Parsons MW, 2010, '68. Final infarct volume can be determined using diffusion imaging 24 hours after stroke onset', Journal of Clinical Neuroscience, 17, pp. 1630 - 1631, http://dx.doi.org/10.1016/j.jocn.2010.07.069

Tu HTH; Campbell BCV; Christensen S; Collins M; Parsons MW; Barber PA; Donnan GA; Davis SM, 2010, '93. Worse stroke outcome in patients with atrial fibrillation may be due to greater volumes of more severe hypoperfusion', Journal of Clinical Neuroscience, 17, pp. 1637 - 1637, http://dx.doi.org/10.1016/j.jocn.2010.07.094

Simpson M; Dewey H; Churilov L; Ahmed N; Bladin CF; Shultz D; Markus R; Sturman JJ; Levi C; Blacker DJ; Jannes J; Lindley R; Parsons M, 2010, 'Thrombolysis for acute stroke in Australia: Outcomes from the safe implementation of Thrombolysis in stroke registry (2002-2008)', , 193, pp. 439 - 443

Hubbard IJ; Parsons MW; Neilson C; Carey LM, 2009, 'Task-specific training: Evidence for and translation to clinical practice', Occupational Therapy International, 16, pp. 175 - 189, http://dx.doi.org/10.1002/oti.275

De Silva DA; Fink JN; Christensen S; Ebinger M; Bladin C; Levi CR; Parsons M; Butcher K; Barber PA; Donnan GA; Davis SM, 2009, 'Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET)', Stroke, 40, pp. 2872 - 2874, http://dx.doi.org/10.1161/STROKEAHA.108.543595

Ebinger M; Iwanaga T; Prosser JF; De Silva DA; Christensen S; Collins M; Parsons MW; Levi CR; Bladin CF; Barber PA; Donnan GA; Davis SM, 2009, 'Clinical-diffusion mismatch and benefit from thrombolysis 3 to 6 hours after acute stroke', Stroke, 40, pp. 2572 - 2574, http://dx.doi.org/10.1161/STROKEAHA.109.548073

Hubbard IJ; Vyslysel G; Parsons MW, 2009, 'Interprofessional, practice-driven research: Reflections of one "community of inquiry" based in acute stroke', Journal of Allied Health, 38

Levi C; Lindley R; Smith B; Bladin C; Parsons M; Read S; Cadilhac D; Donnan G; Davis S; Hankey G; Crimmins D; Gerraty R; Blacker D; Schultz D; Grimley R; Lalor E, 2009, 'The implementation of intravenous tissue plasminogen activator in acute ischaemic stroke - A scientific position statement from the National Stroke foundation and the Stroke Society of Australasia', Internal Medicine Journal, 39, pp. 317 - 324, http://dx.doi.org/10.1111/j.1445-5994.2009.01938.x

Ebinger M; Christensen S; De Silva DA; Parsons MW; Levi CR; Butcher KS; Bladin CF; Barber PA; Donnan GA; Davis SM, 2009, 'Expediting MRI-based proof-of-concept stroke trials using an earlier imaging end point', Stroke, 40, pp. 1353 - 1358, http://dx.doi.org/10.1161/STROKEAHA.108.532622

Parsons MW; Miteff F; Bateman GA; Spratt N; Loiselle A; Attia J; Levi CR, 2009, 'Acute ischemic stroke: Imaging-guided tenecteplase treatment in an extended time window', Neurology, 72, pp. 915 - 921, http://dx.doi.org/10.1212/01.wnl.0000344168.05315.9d

Ebinger M; De Silva DA; Christensen S; Parsons MW; Markus R; Donnan GA; Davis SM, 2009, 'Imaging the penumbra - strategies to detect tissue at risk after ischemic stroke', Journal of Clinical Neuroscience, 16, pp. 178 - 187, http://dx.doi.org/10.1016/j.jocn.2008.04.002

De Silva DA; Ebinger M; Christensen S; Parsons MW; Levi C; Butcher K; Barber PA; Bladin C; Donnan GA; Davis SM, 2009, 'Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial', Cerebrovascular Diseases, 29, pp. 14 - 21, http://dx.doi.org/10.1159/000255969

Arima H; Wang JG; Huang Y; Heeley E; Skulina C; Parsons MW; Peng B; Li Q; Su S; Tao QL; Li YC; Jiang JD; Tai LW; Zhang JL; Xu E; Cheng Y; Morgenstern LB; Chalmers J; Anderson CS, 2009, 'Significance of perihematomal edema in acute intracerebral hemorrhage: The INTERACT trial', Neurology, 73, pp. 1963 - 1968, http://dx.doi.org/10.1212/WNL.0b013e3181c55ed3

Miteff F; Levi CR; Bateman GA; Spratt N; McElduff P; Parsons MW, 2009, 'The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke', Brain, 132, pp. 2231 - 2238, http://dx.doi.org/10.1093/brain/awp155

Campbell B; Christensen S; Butcher K; Gordan I; Parsons M; Desmond P; Barber P. A; Levi C; Bladin C; De Silva D; Peeters A; Donnan G; Davis S, 2009, '12. Very Low Cerebral Blood Volume (VLCBV) – a new predictor of haemorrhagic transformation after thrombolysis for acute ischaemic stroke', Journal of Clinical Neuroscience, 16, pp. 1527 - 1527, http://dx.doi.org/10.1016/j.jocn.2009.07.037

Campbell B; Christensen S; Foster S; Butcher K; De Silva D; Peeters A; Desmond P; Parsons M; Levi C; Barber PA; Bladin C; Donnan G; Davis S, 2009, '13. Online visual assessment of the PWI/DWI penumbra has limited agreement with volumetric mismatch', Journal of Clinical Neuroscience, 16, pp. 1527 - 1528, http://dx.doi.org/10.1016/j.jocn.2009.07.038

Campbell B; Christensen S; Butcher K; Gordan I; Parsons M; Desmond P; Barber PA; Levi C; Bladin C; De Silva D; Peeters A; Donnan G; Davis S, 2009, 'Very Low Cerebral Blood Volume (VLCBV) – A New Predictor of Haemorrhagic Transformation after Thrombolysis for Acute Ischaemic Stroke', Journal of Clinical Neuroscience, 16, pp. 1514 - 1515, http://dx.doi.org/10.1016/j.jocn.2009.07.006

Quain DA; Parsons MW; Loudfoot AR; Spratt NJ; Evans MK; Russell ML; Royan AT; Moore AG; Miteff F; Hullick CJ; Attia J; McElduff P; Levi CR, 2008, 'Improving access to acute stroke therapies: A controlled trial of organised pre-hospital and emergency care', Medical Journal of Australia, 189, pp. 429 - 433, http://dx.doi.org/10.5694/j.1326-5377.2008.tb02114.x

Dienert H-C; Saccot RL; Yusuft S; Cotton D; Ounpuu S; Lawton WA; Palesch Y; Martin RH; Albers GW; Bath P; Bornstein N; Chan BPL; Chen S-T; Cunha L; Dahlof B; De Keyser J; Donnan GA; Estol C; Gorelick P; Gu V; Hermansson K; Hilbrich L; Kaste M; Lu C; Machnig T; Pais P; Roberts R; Skvortsova V; Teal P; Toni D; VanderMaelen C; Voigt T; Weber M; Yoon B-W, 2008, 'Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study', LANCET NEUROLOGY, 7, pp. 875 - 884, http://dx.doi.org/10.1016/S1474-4422(08)70198-4

Anderson C; Pogue J; Dyal L; Copland I; Schumacher H; Dagenais G; Sleight P; Ramos B; Richardson L; Murphy J; Haehl M; Hilbrich L; Svaerd R; Martin K; Murwin D; Meinicke T; Schlosser A; Schmidt G; Creek R; Distel M; Aubert B; Schmieder R; Unger T; Asmar R; Mancia G; Diaz R; Paolasso E; Piegas L; Avezum A; Cardona Munoz E; Probstfield J; Weber M; Young J; Fagard R; Jansky P; Mallion J; Mann J; Böhm M; Eber B; Karatzas NB; Keltai M; Trimarco B; Verdecchia P; Maggioni A; Verheugt FWA; Holwerda NJ; Ceremuzynski L; Budaj A; Ferreira R; Chazova I; Rydén L; Svendsen TL; Metsärinne K; Dickstein K; Fodor G; Commerford P; Redon J; Luescher TR; Oto A; Binbrek A; Parkhomenko A; Jennings G; Liu LS; Yu CM; Dans AL; Shah R; Kim JH; Chen JH; Chaithiraphan S; Cairns J; Wilhelmsen L; Chalmers J; Wittes J; Gent M; Hennekens CH; Anderson N; Yusoff K; Auger P; Bernstein V; Panju A; Anand I; Bigger JT; Linz P; Healey J; Held C; McGorrian C; Rokoss M; Villar J; Teo K; McDonald A; Schweitzer D; Cunningham J; Wagan E; Boland T; Westfall L; Gulliver N; Oliveira R; McLean-Price C; Kotlan S, 2008, 'Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial', The Lancet, 372, pp. 1174 - 1183, http://dx.doi.org/10.1016/S0140-6736(08)61242-8

Sacco RL; Diener H-C; Yusuf S; Cotton D; Ounpuu S; Lawton WA; Palesch Y; Martin RH; Albers GW; Bath P; Bornstein N; Chan BPL; Chen S-T; Cunha L; Dahlof B; De Keyser J; Donnan GA; Estol C; Gorelick P; Gu V; Hermansson K; Hilbrich L; Kaste M; Lu C; Machnig T; Pais P; Roberts R; Skvortsova V; Teal P; Toni D; VanderMaelen C; Voigt T; Weber M; Yoon B-W, 2008, 'Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke', NEW ENGLAND JOURNAL OF MEDICINE, 359, pp. 1238 - 1251, http://dx.doi.org/10.1056/NEJMoa0805002

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