By Professor Megan Lord

Book Chapters

Vassie JA; Whitelock JM; Lord MS, 2015, 'Glycosaminoglycan functionalized nanoparticles exploit glycosaminoglycan functions', in Balagurunathan K; Nakato H; Desai UR (ed.), Glycosaminoglycans, Springer Nature, pp. 557 - 565, http://dx.doi.org/10.1007/978-1-4939-1714-3_44

Journal articles

Jiang S; Yang N; Tan RP; Moh ESX; Fu L; Packer NH; Whitelock JM; Wise SG; Rnjak-Kovacina J; Lord MS, 2024, 'Tuning Recombinant Perlecan Domain V to Regulate Angiogenic Growth Factors and Enhance Endothelialization of Electrospun Silk Vascular Grafts', Advanced Healthcare Materials, 13, http://dx.doi.org/10.1002/adhm.202400855

Fu L; Bridges CA; Kim HN; Ding C; Bao Hou NC; Yeow J; Fok S; Macmillan A; Sterling JD; Baker SM; Lord MS, 2024, 'Cationic Polysaccharides Bind to the Endothelial Cell Surface Extracellular Matrix Involving Heparan Sulfate', Biomacromolecules, 25, pp. 3850 - 3862, http://dx.doi.org/10.1021/acs.biomac.4c00477

Jiang S; Wise SG; Kovacic JC; Rnjak-Kovacina J; Lord MS, 2024, 'Biomaterials containing extracellular matrix molecules as biomimetic next-generation vascular grafts', Trends in Biotechnology, 42, pp. 369 - 381, http://dx.doi.org/10.1016/j.tibtech.2023.09.009

Adhikari A; Abayasingam A; Brasher NA; Kim HN; Lord M; Agapiou D; Maher L; Rodrigo C; Lloyd AR; Bull RA; Tedla N, 2024, 'Characterization of antibody-dependent cellular phagocytosis in patients infected with hepatitis C virus with different clinical outcomes', Journal of Medical Virology, 96, http://dx.doi.org/10.1002/jmv.29381

Kim HN; Elgundi Z; Lin X; Fu L; Tang F; Moh ESX; Jung MS; Chandrasekar K; Bartlett-Tomasetig F; Foster C; Packer NH; Whitelock JM; Rnjak-Kovacina J; Lord MS, 2023, 'Engineered short forms of perlecan enhance angiogenesis by potentiating growth factor signalling', Journal of Controlled Release, 362, pp. 184 - 196, http://dx.doi.org/10.1016/j.jconrel.2023.08.052

Lau K; Fu L; Zhang A; Akhavan B; Whitelock J; Bilek MM; Lord MS; Rnjak-Kovacina J, 2023, 'Recombinant perlecan domain V covalently immobilized on silk biomaterials via plasma immersion ion implantation supports the formation of functional endothelium', Journal of Biomedical Materials Research - Part A, 111, pp. 825 - 839, http://dx.doi.org/10.1002/jbm.a.37525

Joukhdar H; Och Z; Tran H; Heu C; Vasquez GM; Sultana N; Stevens M; Dokos S; Lim KS; Lord MS; Rnjak-Kovacina J, 2023, 'Imparting Multi-Scalar Architectural Control into Silk Materials Using a Simple Multi-Functional Ice-Templating Fabrication Platform', Advanced Materials Technologies, 8, http://dx.doi.org/10.1002/admt.202201642

Sterling JD; Fu L; Pudun K; Baker S; Lord M, 2023, 'Salt doping of hyaluronic acid glycopolymer biocondensates', Biophysical journal, 122, http://dx.doi.org/10.1016/j.bpj.2022.11.1236

Adhikari A; Abayasingam A; Rodrigo C; Agapiou D; Pandzic E; Brasher NA; Fernando BSM; Keoshkerian E; Li H; Kim HN; Lord M; Popovic G; Rawlinson W; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Grubor-Bauk B; Lloyd AR; Martinello M; Bull RA; Tedla N; Kaldor J; Dore G; Sorrell T; Bartlett A; Lemberg D; Di Girolamo N; Byrne M; Hammoud M; Sultan R; Konecny P; Matthews G; Shek D; Holdaway S; Mitsa-Kos K; How-Chow D; Lagunday R; Robinson S; Terrill L; Joshi N; Li Y; Gill S; Sevehon A, 2022, 'Longitudinal Characterization of Phagocytic and Neutralization Functions of Anti-Spike Antibodies in Plasma of Patients after Severe Acute Respiratory Syndrome Coronavirus 2 Infection', Journal of Immunology, 209, pp. 1499 - 1512, http://dx.doi.org/10.4049/jimmunol.2200272

Karimi F; Lau K; Kim HN; Och Z; Lim KS; Whitelock J; Lord M; Rnjak-Kovacina J, 2022, 'Surface Biofunctionalization of Silk Biomaterials Using Dityrosine Cross-Linking', ACS Applied Materials and Interfaces, 14, pp. 31551 - 31566, http://dx.doi.org/10.1021/acsami.2c03345

Liu J; Xue J; Fu L; Xu J; Lord MS; Liang K, 2022, 'Genetically Encoded Synthetic Beta Cells for Insulin Biosynthesis and Release under Hyperglycemic Conditions', Advanced Functional Materials, 32, http://dx.doi.org/10.1002/adfm.202111271

Fu L; Kim HN; Sterling JD; Baker SM; Lord MS, 2022, 'The role of the cell surface glycocalyx in drug delivery to and through the endothelium', Advanced Drug Delivery Reviews, 184, pp. 114195, http://dx.doi.org/10.1016/j.addr.2022.114195

Lau K; Heu C; Moore MJ; Zhang A; Akhavan B; Wise SG; Bilek MMM; Lord MS; Rnjak-Kovacina J, 2022, 'Effect of plasma ion immersion implantation on physiochemical and biological properties of silk towards creating a versatile biomaterial platform', Materials Today Advances, 13, http://dx.doi.org/10.1016/j.mtadv.2022.100212

Yong JM; Fu L; Tang F; Yu P; Kuchel RP; Whitelock JM; Lord MS, 2022, 'ROS-Mediated Anti-Angiogenic Activity of Cerium Oxide Nanoparticles in Melanoma Cells', ACS Biomaterials Science and Engineering, 8, pp. 512 - 525, http://dx.doi.org/10.1021/acsbiomaterials.1c01268

Fu L; Li R; Whitelock JM; Lord MS, 2022, 'Tuning the intentional corona of cerium oxide nanoparticles to promote angiogenesis via fibroblast growth factor 2 signalling', Regenerative Biomaterials, 9, http://dx.doi.org/10.1093/rb/rbac081

Lehmann RJ; Jolly LA; Johnson BV; Lord MS; Kim HN; Saville JT; Fuller M; Byers S; Derrick-Roberts ALK, 2021, 'Impaired neural differentiation of MPS IIIA patient induced pluripotent stem cell-derived neural progenitor cells', Molecular Genetics and Metabolism Reports, 29, http://dx.doi.org/10.1016/j.ymgmr.2021.100811

Lord MS; Berret JF; Singh S; Vinu A; Karakoti AS, 2021, 'Redox Active Cerium Oxide Nanoparticles: Current Status and Burning Issues', Small, 17, http://dx.doi.org/10.1002/smll.202102342

Liang J; Liu J; Lord MS; Wang Y; Liang K, 2021, 'De Novo Engineering of Metal–Organic Framework-Printed In Vitro Diagnostic Devices for Specific Capture and Release of Tumor Cells', Small, 17, pp. e2103590 - e2103590, http://dx.doi.org/10.1002/smll.202103590

Lau K; Waterhouse A; Akhavan B; Gao L; Kim HN; Tang F; Whitelock JM; Bilek MM; Lord MS; Rnjak-Kovacina J, 2021, 'Biomimetic silk biomaterials: Perlecan-functionalized silk fibroin for use in blood-contacting devices', Acta Biomaterialia, 132, pp. 162 - 175, http://dx.doi.org/10.1016/j.actbio.2021.02.014

Joukhdar H; Seifert A; Jüngst T; Groll J; Lord MS; Rnjak-Kovacina J, 2021, 'Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications', Advanced Materials, 33, http://dx.doi.org/10.1002/adma.202100091

Chandrasekar K; Farrugia BL; Johnson L; Marks D; Irving D; Elgundi Z; Lau K; Kim HN; Rnjak-Kovacina J; Bilek MM; Whitelock JM; Lord MS, 2021, 'Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride', Advanced Healthcare Materials, 10, http://dx.doi.org/10.1002/adhm.202100388

Ng CY; Whitelock JM; Williams H; Kim HN; Medbury HJ; Lord MS, 2021, 'Macrophages bind LDL using heparan sulfate and the perlecan protein core', Journal of Biological Chemistry, 296, pp. 100520, http://dx.doi.org/10.1016/j.jbc.2021.100520

Lord MS; Melrose J; Day AJ; Whitelock JM, 2020, 'The Inter-α-Trypsin Inhibitor Family: Versatile Molecules in Biology and Pathology', Journal of Histochemistry and Cytochemistry, 68, pp. 907 - 927, http://dx.doi.org/10.1369/0022155420940067

Reijmers RM; Troeberg L; Lord MS; Petrey AC, 2020, 'Editorial: Proteoglycans and Glycosaminoglycan Modification in Immune Regulation and Inflammation', Frontiers in Immunology, 11, pp. 595867, http://dx.doi.org/10.3389/fimmu.2020.595867

Lau K; Akhavan B; Lord MS; Bilek MM; Rnjak-Kovacina J, 2020, 'Dry Surface Treatments of Silk Biomaterials and Their Utility in Biomedical Applications', ACS Biomaterials Science and Engineering, 6, pp. 5431 - 5452, http://dx.doi.org/10.1021/acsbiomaterials.0c00888

Liu J; Guo Z; Kordanovski M; Kaltbeitzel J; Zhang H; Cao Z; Gu Z; Wich PR; Lord M; Liang K, 2020, 'Metal-organic frameworks as protective matrices for peptide therapeutics', Journal of Colloid and Interface Science, 576, pp. 356 - 363, http://dx.doi.org/10.1016/j.jcis.2020.05.057

Lin X; Tang F; Jiang S; Khamis H; Bongers A; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials', Adv. Sci., 7, pp. 2000900, http://dx.doi.org/10.1002/advs.202000900

Gao J; Wang WQ; Pei Q; Lord MS; Yu HJ, 2020, 'Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy', Acta Pharmacologica Sinica, 41, pp. 986 - 994, http://dx.doi.org/10.1038/s41401-020-0400-z

Bansal R; Elgundi Z; Goodchild SC; Care A; Lord MS; Rodger A; Sunna A, 2020, 'The effect of oligomerization on a solid-binding peptide binding to silica-based materials', Nanomaterials, 10, http://dx.doi.org/10.3390/nano10061070

Lord M; Whitelock J; Turnbull JE, 2020, 'Better growth-factor binding aids tissue repair', Nature Biomedical Engineering, 4, pp. 368 - 369, http://dx.doi.org/10.1038/s41551-020-0548-3

Tang F; Manz XD; Bongers A; Odell RA; Joukhdar H; Whitelock JM; Lord MS; Rnjak-Kovacina J, 2020, 'Microchannels are an architectural cue that promotes integration and vascularization of silk biomaterials in vivo', ACS Biomaterials Science and Engineering, 6, pp. 1476 - 1486, http://dx.doi.org/10.1021/acsbiomaterials.9b01624

Bansal R; Elgundi Z; Care A; Goodchild SC; Lord MS; Rodger A; Sunna A, 2020, 'Elucidating the binding mechanism of a novel silica-binding peptide', Biomolecules, 10, pp. 4, http://dx.doi.org/10.3390/biom10010004

Piloni A; Wong CK; Chen F; Lord M; Walther A; Stenzel MH, 2019, 'Surface roughness influences the protein corona formation of glycosylated nanoparticles and alter their cellular uptake', Nanoscale, 11, pp. 23259 - 23267, http://dx.doi.org/10.1039/c9nr06835j

Bansal R; Care A; Lord MS; Walsh TR; Sunna A, 2019, 'Experimental and theoretical tools to elucidate the binding mechanisms of solid-binding peptides', New Biotechnology, 52, pp. 9 - 18, http://dx.doi.org/10.1016/j.nbt.2019.04.001

Thickett SC; Hamilton E; Yogeswaran G; Zetterlund PB; Farrugia BL; Lord MS, 2019, 'Enhanced osteogenic differentiation of human fetal cartilage rudiment cells on graphene oxide-PLGA hybrid microparticles', Journal of Functional Biomaterials, 10, pp. 33, http://dx.doi.org/10.3390/jfb10030033

Dinoro J; Maher M; Talebian S; Jafarkhani M; Mehrali M; Orive G; Foroughi J; Lord MS; Dolatshahi-Pirouz A, 2019, 'Sulfated polysaccharide-based scaffolds for orthopaedic tissue engineering', Biomaterials, 214, http://dx.doi.org/10.1016/j.biomaterials.2019.05.025

Farrugia BL; Mizumoto S; Lord MS; O’Grady RL; Kuchel RP; Yamada S; Whitelock JM, 2019, 'Hyaluronidase-4 is produced by mast cells and can cleave serglycin chondroitin sulfate chains into lower molecular weight forms', Journal of Biological Chemistry, 294, pp. 11458 - 11472, http://dx.doi.org/10.1074/jbc.RA119.008647

Gunawan C; Lord MS; Lovell E; Wong RJ; Jung MS; Oscar D; Mann R; Amal R, 2019, 'Oxygen-Vacancy Engineering of Cerium-Oxide Nanoparticles for Antioxidant Activity', ACS Omega, 4, pp. 9473 - 9479, http://dx.doi.org/10.1021/acsomega.9b00521

Lu M; Chen F; Cao C; Garvey CJ; Fletcher NL; Houston ZH; Lu H; Lord MS; Thurecht KJ; Stenzel MH, 2019, 'Importance of Polymer Length in Fructose-Based Polymeric Micelles for an Enhanced Biological Activity', Macromolecules, 52, pp. 477 - 486, http://dx.doi.org/10.1021/acs.macromol.8b02381

Palmer JC; Green RA; Boscher F; Poole-Warren LA; Carter PM; Enke YL; Lovell NH; Lord MS, 2019, 'Development and performance of a biomimetic artificial perilymph for in vitro testing of medical devices', Journal of Neural Engineering, 16, pp. 026006, http://dx.doi.org/10.1088/1741-2552/aaf482

Lord MS; Tang F; Rnjak-Kovacina J; Smith JGW; Melrose J; Whitelock JM, 2018, 'The multifaceted roles of perlecan in fibrosis', Matrix Biology, 68-69, pp. 150 - 166, http://dx.doi.org/10.1016/j.matbio.2018.02.013

Farrugia B; Mi Y; Kim HN; Whitelock J; Baker S; Wiesmann W; Li Z; Maitz P; Lord M, 2018, 'Chitosan‐Based Heparan Sulfate Mimetics Promote Epidermal Formation in a Human Organotypic Skin Model', Advanced Functional Materials, 28, http://dx.doi.org/10.1002/adfm.201802818

Kondyurin A; Lau K; Tang F; Akhavan B; Chrzanowski W; Lord MS; Rnjak-Kovacina J; Bilek MM, 2018, 'Plasma Ion Implantation of Silk Biomaterials Enabling Direct Covalent Immobilization of Bioactive Agents for Enhanced Cellular Responses', ACS Applied Materials and Interfaces, 10, pp. 17605 - 17616, http://dx.doi.org/10.1021/acsami.8b03182

Farrugia BL; Lord MS; Whitelock JM; Melrose J, 2018, 'Harnessing chondroitin sulphate in composite scaffolds to direct progenitor and stem cell function for tissue repair', Biomaterials Science, 6, pp. 947 - 957, http://dx.doi.org/10.1039/c7bm01158j

Farrugia BL; Lord MS; Melrose J; Whitelock JM, 2018, 'The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies', Journal of Histochemistry and Cytochemistry, 66, pp. 321 - 336, http://dx.doi.org/10.1369/0022155417740881

Lord M; Rnjak-Kovacina J; Tang F; Whitelock J, 2018, 'Glycosaminoglycan and Proteoglycan-Based Biomaterials: Current Trends and Future Perspectives', Advanced Healthcare Materials, 7, pp. 1701042 - 1701042, http://dx.doi.org/10.1002/adhm.201701042

Vassie JA; Whitelock JM; Lord MS, 2018, 'Targeted Delivery and Redox Activity of Folic Acid-Functionalized Nanoceria in Tumor Cells', Molecular Pharmaceutics, 15, pp. 994 - 1004, http://dx.doi.org/10.1021/acs.molpharmaceut.7b00920

Tang F; Lord M; Stallcup W; Whitelock J, 2018, 'Cell surface chondroitin sulfate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulfate proteoglycan, perlecan, and is involved in cell adhesion', The Journal of Biochemistry

Palmer JC; Lord MS; Pinyon JL; Wise AK; Lovell NH; Carter PM; Enke YL; Housley GD; Green RA; Palmer J, 2018, 'Comparing perilymph proteomes across species', Laryngoscope, 128, pp. E47 - E52, http://dx.doi.org/10.1002/lary.26885

Back to profile page