Select Publications

Journal articles

Fairfield H; Falank C; Harris E; Demambro V; McDonald M; Pettitt JA; Mohanty ST; Croucher P; Kramer I; Kneissel M; Rosen CJ; Reagan MR, 2018, 'The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis', Journal of Cellular Physiology, 233, pp. 1156 - 1167, http://dx.doi.org/10.1002/jcp.25976

Medina-Gomez C; Kemp JP; Trajanoska K; Luan J; Chesi A; Ahluwalia TS; Mook-Kanamori DO; Ham A; Hartwig FP; Evans DS; Joro R; Nedeljkovic I; Zheng HF; Zhu K; Atalay M; Liu CT; Nethander M; Broer L; Porleifsson G; Mullin BH; Handelman SK; Nalls MA; Jessen LE; Heppe DHM; Richards JB; Wang C; Chawes B; Schraut KE; Amin N; Wareham N; Karasik D; Van der Velde N; Ikram MA; Zemel BS; Zhou Y; Carlsson CJ; Liu Y; McGuigan FE; Boer CG; Bønnelykke K; Ralston SH; Robbins JA; Walsh JP; Zillikens MC; Langenberg C; Li-Gao R; Williams FMK; Harris TB; Akesson K; Jackson RD; Sigurdsson G; den Heijer M; van der Eerden BCJ; van de Peppel J; Spector TD; Pennell C; Horta BL; Felix JF; Zhao JH; Wilson SG; de Mutsert R; Bisgaard H; Styrkársdóttir U; Jaddoe VW; Orwoll E; Lakka TA; Scott R; Grant SFA; Lorentzon M; van Duijn CM; Wilson JF; Stefansson K; Psaty BM; Kiel DP; Ohlsson C; Ntzani E; van Wijnen AJ; Forgetta V; Ghanbari M; Logan JG; Williams GR; Bassett JHD; Croucher PI; Evangelou E; Uitterlinden AG; Ackert-Bicknell CL; Tobias JH; Evans DM; Rivadeneira F, 2018, 'Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects', American Journal of Human Genetics, 102, pp. 88 - 102, http://dx.doi.org/10.1016/j.ajhg.2017.12.005

McDonald MM; Morse A; Schindeler A; Mikulec K; Peacock L; Cheng T; Bobyn J; Lee L; Baldock PA; Croucher PI; Tam PPL; Little DG, 2018, 'Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation', Calcified Tissue International, 102, pp. 105 - 116, http://dx.doi.org/10.1007/s00223-017-0338-4

Bradley M; Martin I; Roelofs A; Khosla S; Mahajan S; Heller MO; Schneider P; Bonewald L; Lillycrop K; Hanson M; Lord J; Cummings SR; Maes C; Bhimjiyani AG; Neuburger J; Ben‐Shlomo Y; Gregson CL; Leitch VD; Sparkes P; Logan JG; Swiatkowska A; Croucher PI; Lelliott CJ; Williams GR; Bassett JHD; Paton‐Hough J; Tazzyman S; Evans H; Lath D; Down J; Green A; Snowden J; Lawson M; Chantry A; Parsons C; Harvey N; Shepstone L; Kanis JA; Lenaghan E; Clarke S; Fordham R; Gittoes N; Harvey I; Holland R; Heawood A; Redmond N; Howe A; Marshall T; Peters T; Torgerson D; O'Neill TW; McCloskey E; Cooper C; Ireland A; Muthuri S; Saunders F; Pavlova A; Hardy R; Martin K; Barr R; Adams J; Kuh D; Aspden R; Gregory J; Cooper R; Vlachopoulo D; Barker A; Ubago‐Guisado E; Williams C; Gracia‐Marco L; Curtis EM; Maslin K; D'Angelo S; Moon RJ; Crozier SR; Gossiel F; Bishop NJ; Kennedy S; Papageorghiou AT; Fraser R; Gandhi SV; Prentice A; Inskip HM; Godfrey KM; Schoenmakers I; Javaid MK; Eastell R; Cooper C; Harvey NC; Fuggle N; Westbury L; Syddall H; Ward K; Duggal N; Lord J; Cooper C; Dennison E; Bonnet C; Gilbert S; Eccles E; Norman K; Mason D; Pereira M; Ko J; Logan J; Petretto E; Bassett JHD; Williams GR; Behmoaras J; de Andres MC; Madhusudan N; Bountra C; Oppermann U; Oreffo ROC; Goriainov V; McEwan J; White K; Oreffo R; Dunlop D; Cornish J; Goring A; Boyde A; Hesse E; Ferrara N; Olsen B; Pitsilides A; Oreffo R; Schneider P; Clarkin C; Hartley A; Paternoster L; Kemp J; Evans D; Tang J; Fraser W; Tobias JH; Gregson CL; McCloskey E; Harvey N; Johansson H; Shepstone L; Lenaghan E; Cooper C; Kanis J; Roberts F; Rashdan N; Orriss I; Staines K; Milne E; Ahmed F; Morton N; Farquharson C; MacRae V; McCulloch K; Huesa C; Dunning L; van't Hof R; Lockhart J; Goodyear C; Thomas NP; Jeffery N; Ranganath L; Boyde A; Gallagher J; Breasail MÓ; Prentice A; Ward K; Reid I; Horne A; Mihov B; Stewart A; Garratt L; Bolland M; Bastin S; Gamble G; Javaid M; Delmestri A; Shaw N; Prieto‐Alhambra D; Cooper C; Pinedo‐Villanueva R; Hughes J; Wilson P; Liu K; Hughes A; Ranganath L; Gallagher J; Bou‐Gharios G; Nijjar JS; Padley J; Poole K; Westbury L; Litwic A; Ward K; Cooper C; Dennison E; Edwards M; Westbury L; Cooper C; Dennison E; Ward K; Ishimoto Y; Cooper C; Ntani G; Yamada H; Hashizume H; Muraki S; Tanaka S; Yoshida M; Yoshimura N; Walker‐Bone K; Tan J; Poole K; Larrouture Q; Knowles H; Snelling S; Athanasou N; Al‐sari UA; Tobias JH; Clark EM; Doube M; Felder AA; Chua MY; Lodhia K; Kłosowski MM; Hutchinson JR; Shefelbine SJ; Dillon S; Nudelman F; Farquharson C; Kanczler J; Inglis S; Schneider K; Redl H; Oreffo R; Pollard AS; Gogakos A; Logan JG; Ebri DK; Sparkes PC; Butterfield NC; Leitch VD; Pipelines SM; Croucher PI; Bassett JHD; Williams GR; Cidonio G; Ahlfeld T; Glinka M; Kim Y; Lanham S; Kanczler J; Yang S; Dawson J; Gelinsky M; Oreffo R; McEwan J; Kanczler J; Lanham S; Wells J; Dawson J; Oreffo R; Yoshimura N; Muraki S; Oka H; Iidaka T; Kodama R; Horii C; Kawaguchi H; Nakamura K; Akune T; Tanaka S; Green A; Hudson K; Down J; Lath D; Evans H; Paton‐Hough J; Tazzyman S; Fisher M; Snowden J; Chantry A; Lawson M; Butterfield NC; Miszkiewicz J; Adoum A; Logan J; Leitch V; Yoshimura T; Bassett D; Williams G; Mannan NS; Leitch VD; Logan JG; Adoum A; Dewhurst HF; Pollard AS; Sparkes PC; Ghirardello EJ; Allen R; Butterfield NC; Pipelines SM; Komla‐Ebri D; Curry KF; Croucher PI; Williams GR; 𠀉 JH; Bassett D; Ganguly P; El‐Jawhari JJ; Burska AN; Ponchel F; Giannoudis PV; Jones EA; Komla‐Ebri D; Gogakos A; Sparkes P; Logan JG; Croucher PI; Bassett JHD; Williams GR; Ghirardello EJ; Logan JG; Sparkes PC; Curry KF; Miszkiewicz JJ; Leitch VD; Butterfield NC; Croucher PI; Williams GR; Bassett JHD; Pipelines SM; Rashdan N; Sim A; Hohenstein P; Hung J; Kaczynski J; Newby D; Baker A; Karsenty G; MacRae V; Hsu S; MacRae V; Novak A; Staines K; Farquharson C; Boyde A; Mills D; Gilbert S; Bonnet C; Ihenacho M; Cronin R; Blain E; Mason D; Rodriguez A; Xu C; McMillan L; Srikanth V; Scott D; Ebeling P; Goring A; Javaheri B; Ferrara N; Olsen B; Schneider P; Oreffo R; Pitsillides A; Clarkin C; Jones T; Clynes M; Jameson K; Prieto‐Alhambra D; Harvey N; Cooper C; Dennison E; Stephenson S; Ersek A; Cosulich C; Udalova I; Horwood N; Fuggle N; Jameson K; Edwards M; Dennison E; Cooper C; Sano H; Kondo N; Shimakura T; Fujisawa J; Kijima Y; Skingle L; Poole K; Yamamoto N; Takahashi H; Endo N; Beamish R; Ayre W; Evans S; Morgan S; Hooper K; Halewood K; Milne E; Farquharson C; Stevens C; Staines K; Mandair GS; Steenhuis P; Jr MAI; Morris MD; Mandair GS; Karabetsos M; Vanrenterghem GG; Ayyalusamy R; Morris MD; Kohn DH; Kadamban P; Galloway J; Skingle L; Vaughan‐Lane T; Wright M; Brassett C; Poole K; Parsons C; Judge A; Leyland K; Inskip H; Cooper C; Bourne LE; Patel JJ; Neven E; D'Haese P; Wheeler‐Jones C; Orriss IR; Hartley A; Rukuni R; Crabtree N; Mukwasi C; Majonga E; McHugh G; Mujuru H; Ferrand R; Gregson CL; Chen J; Luo J; Dodhia VH; Cidonio G; Kim Y; Oreffo ROC; Dawson JI; Glinka M; Cidonio G; Geng J; Czekańska E; Kim Y; Dawson JI; Yang S; Lim K; Woodfield T; Bradley M; Oreffo R; Arnold E; Greenwood C; Rogers K; McGivern H; Greenwood C; Marquez‐Grant N; Zioupos P; Gohin S; Soper R; Javaheri B; Ytrebø LM; Hopkinson M; Meeson R; Howat D; Pitsillides A; Hodges S; Williams KA; Gostling NJ; Dyke G; Oreffo ROC; Schneider P; Evelyn‐Wright S; Browne M; Woods C; Mavrogordato M; Rankin K; Stocks O; Dickinson A; Zakrzewski S; Hartley C; Folland J; Kerslake R; Brooke‐Wavell K; Kim Y; Ossipov D; Oreffo ROC; Dawson JI; Thomson S; Lu W; Muderis MA; Thomson S; Lu W; Muderis MA; Arden N; Edwards JR; Kluzek S; Sowman A; Sanchez‐Santos MT; Hart D; Spector TD; Ismail O; Coxon J; Townsend P; Jones R; Lawrence K; Breasail MÓ; Prentice A; Ward K; Egan B; Birchall J; Heard C; Mason D; Tattersall L; Marchi ED; Virgilio FD; Lawson M; Adinolfi E; Gartland A; Moura CC; Tare RS; Oreffo ROC; Mahajan S; Xavier M; Holm S; Beech J; Spencer D; Tegenfeldt J; Oreffo ROC; Morgan H; Martin J; Murphy C; Gregory J; Aspden R; Riemen A; Saunders F; Murphy C; Martin J; Gregory J; Aspden R; Riemen A; Saunders F; Davies A; Ahmad F; Theobald P; Hugtenburg R; Johnston R; Wintsch E; Piercy R; Doube M; Millar S; Anderson S; O'Sullivan S; Alshamrani HA; Paggiosi MA; Bishop N; Offiah AC; Alshamrani HA; Paggiosi MA; Bishop N; Offiah AC; Pretorius S; Roberts S; Logan M; Johannesdottir F; Allaire B; Anderson DE; Samelson EJ; Kiel DP; Bouxsein ML; Olatokun O; Nash T; Abdul‐Jabar HB; Tran A; Segeletz S; McDermott E; Rochford J; Wileman T; Helfrich M; Tran A; McDermott E; Rochford J; Helfrich M; Knowles H; Redman A; Gilbert S; Elford C; Al‐Sabah A; Blain E; Evans B, 2018, 'Bone Research Society Abstracts', JBMR Plus, 2, http://dx.doi.org/10.1002/jbm4.10073

Hewett DR; Vandyke K; Lawrence DM; Friend N; Noll JE; Geoghegan JM; Croucher PI; Zannettino ACW, 2017, 'DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment', Neoplasia (United States), 19, pp. 972 - 981, http://dx.doi.org/10.1016/j.neo.2017.09.004

Leitch VD; Di CC; Liao X-H; O'Boy S; Galliford TM; Evans H; Croucher PI; Boyde A; Dumitrescu A; Weiss RE; Refetoff S; Williams GR; Duncan BJH, 2017, 'An essential physiological role for MCT8 in bone', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.50.oc1.5

Vandyke K; Zeissig MN; Hewett DR; Martin SK; Mrozik KM; Cheong CM; Diamond P; To LB; Gronthos S; Peet DJ; Croucher PI; Zannettino ACW, 2017, 'HIF-2α promotes dissemination of plasma cells in multiple myeloma by regulating CXCL12/CXCR4 and CCR1', Cancer Research, 77, pp. 5452 - 5463, http://dx.doi.org/10.1158/0008-5472.CAN-17-0115

Nobis M; Herrmann D; Warren SC; Kadir S; Leung W; Killen M; Magenau A; Stevenson D; Lucas MC; Reischmann N; Vennin C; Conway JRW; Boulghourjian A; Zaratzian A; Law AM; Gallego-Ortega D; Ormandy CJ; Walters SN; Grey ST; Bailey J; Chtanova T; Quinn JMW; Baldock PA; Croucher PI; Schwarz JP; Mrowinska A; Zhang L; Herzog H; Masedunskas A; Hardeman EC; Gunning PW; del Monte-Nieto G; Harvey RP; Samuel MS; Pajic M; McGhee EJ; Johnsson AKE; Sansom OJ; Welch HCE; Morton JP; Strathdee D; Anderson KI; Timpson P; del Monte Nieto G, 2017, 'A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts', Cell Reports, 21, pp. 274 - 288, http://dx.doi.org/10.1016/j.celrep.2017.09.022

Kemp JP; Morris JA; Medina-Gomez C; Forgetta V; Warrington NM; Youlten SE; Zheng J; Gregson CL; Grundberg E; Trajanoska K; Logan JG; Pollard AS; Sparkes PC; Ghirardello EJ; Allen R; Leitch VD; Butterfield NC; Komla-Ebri D; Adoum AT; Curry KF; White JK; Kussy F; Greenlaw KM; Xu C; Harvey NC; Cooper C; Adams DJ; Greenwood CMT; Maurano MT; Kaptoge S; Rivadeneira F; Tobias JH; Croucher PI; Ackert-Bicknell CL; Bassett JHD; Williams GR; Richards JB; Evans DM, 2017, 'Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis', Nature Genetics, 49, pp. 1468 - 1475, http://dx.doi.org/10.1038/ng.3949

Chai RC; McDonald MM; Terry RL; Kovačić N; Down JM; Pettitt JA; Mohanty ST; Shah S; Haffari G; Xu J; Gillespie MT; Rogers MJ; Price JT; Croucher PI; Quinn JMW, 2017, 'Melphalan modifies the bone microenvironment by enhancing osteoclast formation', Oncotarget, 8, pp. 68047 - 68058, http://dx.doi.org/10.18632/oncotarget.19152

Leitch VD; Di Cosmo C; Liao XH; O'Boy S; Galliford TM; Evans H; Croucher PI; Boyde A; Dumitrescu A; Weiss RE; Refetoff S; Williams GR; Bassett JHD, 2017, 'An essential physiological role for MCT8 in bone in male mice', Endocrinology, 158, pp. 3055 - 3066, http://dx.doi.org/10.1210/en.2017-00399

McDonald MM; Reagan MR; Youlten SE; Mohanty ST; Seckinger A; Terry RL; Pettitt JA; Simic MK; Cheng TL; Morse A; Le LMT; Abi-Hanna D; Kramer I; Falank C; Fairfield H; Ghobrial IM; Baldock PA; Little DG; Kneissel M; Vanderkerken K; Bassett JHD; Williams GR; Oyajobi BO; Hose D; Phan TG; Croucher PI, 2017, 'Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma', Blood, 129, pp. 3452 - 3464, http://dx.doi.org/10.1182/blood-2017-03-773341

Jaratlerdsiri W; Chan EKF; Petersen DC; Yang C; Croucher PI; Bornman MSR; Sheth P; Hayes VM, 2017, 'Next generation mapping reveals novel large genomic rearrangements in prostate cancer', Oncotarget, 8, pp. 23588 - 23602, http://dx.doi.org/10.18632/oncotarget.15802

Esapa CT; Piret SE; Nesbit MA; Loh NY; Thomas G; Croucher PI; Brown MA; Brown SDM; Cox RD; Thakker RV, 2016, 'Mice with an N-Ethyl-N-Nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway', PLoS ONE, 11, pp. e0167916, http://dx.doi.org/10.1371/journal.pone.0167916

Croucher PI; McDonald MM; Martin TJ, 2016, 'Bone metastasis: The importance of the neighbourhood', Nature Reviews Cancer, 16, pp. 373 - 386, http://dx.doi.org/10.1038/nrc.2016.44

McDonald M; Reagan M; Terry R; Pettitt J; Le L; Mohanty S; Kramer I; Kneissel M; Brooks D; Cheng T; Little D; Bouxsein M; Rosen C; Ghobrial I; Croucher P, 2016, 'Anti-sclerostin treatment prevents multiple myeloma bone disease and reduces tumour burden', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.5.cabs.oc3.4

Kulkarni R; Schindeler A; Croucher P; Little D; Baldock P, 2016, 'Is circulating sclerostin an endocrine modulator of bone mass?', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.5.oc2.5

Kassen D; Lath D; Lach A; Evans H; Chantry A; Rabin N; Croucher P; Yong KL, 2016, 'Myeloma impairs mature osteoblast function but causes early expansion of osteo-progenitors: Temporal changes in bone physiology and gene expression in the KMS12BM model', British Journal of Haematology, 172, pp. 64 - 79, http://dx.doi.org/10.1111/bjh.13790

Khor EC; Fanshawe B; Qi Y; Zolotukhin S; Kulkarni RN; Enriquez RF; Purtell L; Lee NJ; Wee NK; Croucher PI; Campbell L; Herzog H; Baldock PA, 2016, 'Prader-willi critical region, a non-translated, imprinted central regulator of bone mass: Possible role in skeletal abnormalities in Prader-Willi Syndrome', PLoS ONE, 11, pp. e0148155, http://dx.doi.org/10.1371/journal.pone.0148155

Freudenthal B; Logan J; Sanger Institute Mouse Pipelines ; Croucher PI; Williams GR; Duncan Bassett JH, 2016, 'Rapid phenotyping of knockout mice to identify genetic determinants of bone strength', Journal of Endocrinology, 231, pp. 1 - 16, http://dx.doi.org/10.1530/JOE-16-0258

Lawson MA; McDonald MM; Kovacic N; Khoo WH; Terry RL; Down J; Kaplan W; Paton-Hough J; Fellows C; Pettitt JA; Dear TN; Van Valckenborgh E; Baldock PA; Rogers MJ; Eaton CL; Vanderkerken K; Pettit AR; Quinn JMW; Zannettino ACW; Phan TG; Croucher PI, 2015, 'Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms9983

Wang N; Reeves KJ; Brown HK; Fowles ACM; Docherty FE; Ottewell PD; Croucher PI; Holen I; Eaton CL, 2015, 'The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer', Journal of Experimental and Clinical Cancer Research, 34, http://dx.doi.org/10.1186/s13046-015-0240-8

Bassett JHD; Van Der Spek A; Logan JG; Gogakos A; Bagchi-Chakraborty J; Murphy E; Van Zeijl C; Down J; Croucher PI; Boyde A; Boelen A; Williams GR, 2015, 'Thyrostimulin regulates osteoblastic bone formation during early skeletal development', Endocrinology, 156, pp. 3098 - 3113, http://dx.doi.org/10.1210/en.2014-1943

Ottewell PD; Wang N; Brown HK; Fowles CA; Croucher PI; Eaton CL; Holen I, 2015, 'OPG-Fc inhibits ovariectomy-induced growth of disseminated breast cancer cells in bone', International Journal of Cancer, 137, pp. 968 - 977, http://dx.doi.org/10.1002/ijc.29439

Wang N; Docherty F; Brown HK; Reeves K; Fowles A; Lawson M; Ottewell PD; Holen I; Croucher PI; Eaton CL, 2015, 'Mitotic quiescence, but not unique "stemness," marks the phenotype of bone metastasis-initiating cells in prostate cancer', FASEB Journal, 29, pp. 3141 - 3150, http://dx.doi.org/10.1096/fj.14-266379

Gascoyne DM; Spearman H; Lyne L; Puliyadi R; Perez-Alcantara M; Coulton L; Fisher SE; Croucher PI; Banham AH, 2015, 'The forkhead transcription factor FOXP2 is required for regulation of p21waf1/cip1 in 143B osteosarcoma cell growth arrest', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0128513

Esapa CT; Hannan FM; Babinsky VN; Potter P; Thomas GP; Croucher PI; Brown MA; Brown SDM; Cox RD; Thakker RV, 2015, 'N-ethyl-N-nitrosourea (ENU) induced mutations within the Klotho gene lead to ectopic calcification and reduced lifespan in mouse models', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0122650

Croucher PI; Parker BS; Corcoran N; Rogers MJ, 2015, 'Bone turnover markers and prostate cancer: Not just a measure of bone disease?', European Urology, 68, pp. 51 - 52, http://dx.doi.org/10.1016/j.eururo.2014.10.041

Junankar S; Shay G; Jurczyluk J; Ali N; Down J; Pocock N; Parker A; Nguyen A; Sun S; Kashemirov B; McKenna CE; Croucher PI; Swarbrick A; Weilbaecher K; Phan TG; Rogers MJ, 2015, 'Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer', Cancer Discovery, 5, pp. 35 - 42, http://dx.doi.org/10.1158/2159-8290.CD-14-0621

Wang N; Docherty FE; Brown HK; Reeves KJ; Fowles ACM; Ottewell PD; Dear TN; Holen I; Croucher PI; Eaton CL, 2014, 'Prostate cancer cells preferentially home to osteoblast-rich areas in the early stages of bone metastasis: Evidence from in vivo models', Journal of Bone and Mineral Research, 29, pp. 2688 - 2696, http://dx.doi.org/10.1002/jbmr.2300

Ottewell PD; Wang N; Meek J; Fowles CA; Croucher PI; Eaton CL; Holen I, 2014, 'Castration-induced bone loss triggers growth of disseminated prostate cancer cells in bone', Endocrine-Related Cancer, 21, pp. 769 - 781, http://dx.doi.org/10.1530/ERC-14-0199

Kassen D; Moore S; Percy L; Herledan G; Bounds D; Rodriguez-Justo M; Croucher P; Yong KL, 2014, 'The bone marrow stromal compartment in multiple myeloma patients retains capability for osteogenic differentiation in vitro: Defining the stromal defect in myeloma', British Journal of Haematology, 167, pp. 194 - 206, http://dx.doi.org/10.1111/bjh.13020

Duncan Bassett JH; Boyde A; Zikmund T; Evans H; Croucher PI; Zhu X; Park JW; Cheng SY; Williams GR, 2014, 'Thyroid hormone receptor α mutation causes a severe and thyroxine-resistant skeletal dysplasia in female mice', Endocrinology (United States), 155, pp. 3699 - 3712, http://dx.doi.org/10.1210/en.2013-2156

Ottewell PD; Wang N; Brown HK; Reeves KJ; Fowles CA; Croucher PI; Eaton CL; Holen I, 2014, 'Zoledronic acid has differential antitumor activity in the pre- and postmenopausal bone microenvironment in vivo', Clinical Cancer Research, 20, pp. 2922 - 2932, http://dx.doi.org/10.1158/1078-0432.CCR-13-1246

Bentley L; Esapa CT; Nesbit MA; Head RA; Evans H; Lath D; Scudamore CL; Hough TA; Podrini C; Hannan FM; Fraser WD; Croucher PI; Brown MA; Brown SDM; Cox RD; Thakker RV, 2014, 'An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess', Endocrinology, 155, pp. 908 - 922, http://dx.doi.org/10.1210/en.2013-1247

Bassett JHD; Boyde A; Zikmund T; Evans H; Croucher PI; Zhu X; Park JW; Cheng S-Y; Williams GR, 2014, 'TR[alpha] mutation causes a severe and thyroxine-resistant skeletal dysplasia', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.34.oc4.3

Kovacic N; Croucher PI; McDonald MM, 2014, 'Signaling Between Tumor Cells and the Host Bone Marrow Microenvironment', Calcified Tissue International, 94, pp. 125 - 139, http://dx.doi.org/10.1007/s00223-013-9794-7

Buckle C; Faraahi Z; Lawson M; Eaton C; Vanderkerken K; Croucher P, 2013, 'A novel antagonist of the canonical Wnt-signalling pathway, Sostdc1, is expressed in experimental models of myeloma and suppresses bone formation', Bone Abstracts, http://dx.doi.org/10.1530/boneabs.1.pp159

Xu S; De Veirman K; Evans H; Santini GC; Vande Broek I; Leleu X; De Becker A; Van Camp B; Croucher P; Vanderkerken K; Van Riet I, 2013, 'Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo', Acta Pharmacologica Sinica, 34, pp. 699 - 709, http://dx.doi.org/10.1038/aps.2012.182

Bentley L; Esapa CT; Nesbit MA; Head RA; Evans H; Lath D; Hough TA; Podrini C; Fraser WD; Croucher PI; Brown MA; Brown SDM; Cox RD; Thakker RV, 2013, 'An N-ethyl-N-nitrosourea induced Corticotrophin releasing hormone promoter mutation provides a mouse model of Cushing's syndrome', Endocrine Abstracts, pp. 1 - 1, http://dx.doi.org/10.1530/endoabs.31.oc2.6

Esapa CT; Bassett JHD; Evans H; Croucher PI; Williams GR; Thakker RV, 2012, 'Bone Mineral Content and Density.', Curr Protoc Mouse Biol, 2, pp. 365 - 400, http://dx.doi.org/10.1002/9780470942390.mo120124

Xu S; Evans H; Buckle C; De Veirman K; Hu J; Xu D; Menu E; De Becker A; Vande Broek I; Leleu X; Camp BV; Croucher P; Vanderkerken K; Van Riet I, 2012, 'Impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients is associated with a blockade in the deactivation of the Notch signaling pathway', Leukemia, 26, pp. 2546 - 2549, http://dx.doi.org/10.1038/leu.2012.126

Chantry AD; Heath D; Mulivor AW; Pearsall S; Baud'huin M; Coulton L; Evans H; Abdul N; Werner ED; Bouxsein ML; Key ML; Seehra J; Arnett TR; Vanderkerken K; Croucher P, 2012, 'Erratum: Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo', Journal of Bone and Mineral Research, 27, pp. 2038 - 2038, http://dx.doi.org/10.1002/jbmr.1704

Chantry AD; Heath D; Mulivor AW; Pearsall S; Baud'Huin M; Coulton L; Evans H; Abdul N; Werner ED; Bouxsein ML; Key ML; Seehra J; Arnett TR; Vanderkerken K; Croucher P, 2012, 'Erratum: Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo (Journal of Bone and Mineral Research (2010) 25:12 (2633-2646) DOI:10.1002/jbmr.142)', Journal of Bone and Mineral Research, 27, pp. 2036 - 2037, http://dx.doi.org/10.1002/jbmr.1705

Karunaratne A; Esapa CR; Hiller J; Boyde A; Head R; Bassett JHD; Terrill NJ; Williams GR; Brown MA; Croucher PI; Brown SDM; Cox RD; Barber AH; Thakker RV; Gupta HS, 2012, 'Significant deterioration in nanomechanical quality occurs through incomplete extrafibrillar mineralization in rachitic bone: Evidence from in-situ synchrotron X-ray scattering and backscattered electron imaging', Journal of Bone and Mineral Research, 27, pp. 876 - 890, http://dx.doi.org/10.1002/jbmr.1495

Esapa CT; Hough TA; Testori S; Head RA; Crane EA; Chan CPS; Evans H; Bassett JHD; Tylzanowski P; McNally EG; Carr AJ; Boyde A; Howell PGT; Clark A; Williams GR; Brown MA; Croucher PI; Nesbit MA; Brown SDM; Cox RD; Cheeseman MT; Thakker RV, 2012, 'A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation', Journal of Bone and Mineral Research, 27, pp. 413 - 428, http://dx.doi.org/10.1002/jbmr.547

Piret SE; Esapa C; Gorvin CM; Head R; Loh NY; Devuyst O; Thomas GP; Brown S; Brown M; Croucher PI; Cox R; Thakker RV, 2012, 'A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation', PLoS One, 7, pp. e45217, http://dx.doi.org/10.1371/journal.pone.0045217

Esapa C; Head R; Jeyabalan J; Evans HR; Hough TA; Cheeseman M; Mcnally EG; Carr A; Thomas GP; Brown M; Croucher PI; Brown S; Cox R, 2012, 'A mouse with an N-Ethyl-N-Nitrosourea (ENU) induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis', PLoS One, 7, pp. e43205, http://dx.doi.org/10.1371/journal.pone.0043205

Baud''huin M; Solban N; Cornwall-Brady M; Sako D; Kawamoto Y; Liharska K; Lath D; Bouxsein ML; Underwood KW; Ucran JA; Kumar RSP; Pobre EG; Grinberg AV; Seehra JS; Canalis EM; Pearsall RS; Croucher PI, 2012, 'A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength', Proceedings of the National Academy of Sciences of the United States of America, 109, pp. 12207 - 12212, http://dx.doi.org/10.1073/pnas.1204929109

Bassett JHD; Logan JG; Boyde A; Cheung MS; Evans HR; Croucher P; Sun XY; Xu S; Murata Y; Williams GR, 2012, 'Mice lacking the calcineurin inhibitor Rcan2 have an isolated defect of osteoblast function', Endocrinology, 153, pp. 3537 - 3548, http://dx.doi.org/10.1210/en.2011-1814


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