By Professor Peter Ian Croucher

Conference Papers

Khor E-C; Fanashawe B; Qi Y; Croucher P; Herzog H; Baldock P, 2014, 'SNORD116, a Non-translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, TX, Houston, pp. S72 - S72, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, TX, Houston, 12 September 2014 - 15 September 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000356598700214&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Holen I; Wang N; Reeves KJ; Fowles AM; Croucher PI; Eaton CL; Ottewell PD, 2012, 'Abstract PD07-08: Zoledronic acid specifically inhibits development of bone metastases in the post-menopausal setting – evidence from an in vivo breast cancer model', in Cancer Research, American Association for Cancer Research (AACR), http://dx.doi.org/10.1158/0008-5472.sabcs12-pd07-08

Croucher PI; Shipman CM; Van Camp B; Vanderkerken K, 2003, 'Bisphosphonates and osteoprotegerin as inhibitors of myeloma bone disease', in Cancer, pp. 818 - 824, http://dx.doi.org/10.1002/cncr.11125

Shipman CM; Rogers MJ; Vanderkerken K; Van Camp B; Russell RGG; Croucher PI, 2000, 'Bisphosphonates: Mechanisms of action in multiple myeloma', in Acta Oncologica, pp. 829 - 835, http://dx.doi.org/10.1080/028418600750063587

Russell RGG; Croucher PI; Rogers MJ, 1999, 'Bisphosphonates: Pharmacology, mechanisms of action and clinical uses', in Osteoporosis International, pp. S66 - S80, http://dx.doi.org/10.1007/PL00004164

Croucher PI; Wang F; Hargreaves PG, 1999, 'Interleukin-6 receptor shedding: A possible role for members of the ADAM family', in Biochemical Society Transactions, pp. 224 - 228, http://dx.doi.org/10.1042/bst0270224

Russell RGG; Rogers MJ; Frith JC; Luckman SP; Coxon FP; Benford HL; Croucher PI; Shipman C; Fleisch HA, 1999, 'The pharmacology of bisphosphonates and new insights into their mechanisms of action', in Journal of Bone and Mineral Research, pp. 53 - 65, http://dx.doi.org/10.1002/jbmr.5650140212

Conference Abstracts

Kim AS; Castro-Martinez A; Taylor V; Center J; Girgis CM; Croucher PI; Mcdonald MM, 2023, 'OR13-05 Longitudinal Changes In Bone Turnover Following Withdrawal Of RANKL Inhibition', in Journal of the Endocrine Society, The Endocrine Society, Vol. 7, http://dx.doi.org/10.1210/jendso/bvad114.472

Ren Q; Khoo WH; Ye J; Faget DV; Croucher PI; Stewart SA, 2022, 'Abstract 2450: Investigating the intrinsic and extrinsic factors regulating breast cancer dormancy', in Cancer Research, American Association for Cancer Research (AACR), Vol. 82, pp. 2450 - 2450, http://dx.doi.org/10.1158/1538-7445.am2022-2450

Zhou S; Laurent L; Kemp JP; Forgetta V; Morris J; Pramatarova A; Croucher PI; Bassett J; Goltzman D; Evans DM; Richards J, 2020, 'Identifying targets for osteoporosis via whole exome sequencing and CRISPR-Cas9', in EUROPEAN JOURNAL OF HUMAN GENETICS, SPRINGERNATURE, Vol. 28, pp. 134 - 134, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000598482600243&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Zhou S; Laurent L; Kemp J; Pramatarova A; Forgetta V; Morris J; Croucher P; Williams G; Bassett D; Goltzman D; Lotta L; Evans D; Richards B, 2020, 'Identifying Drug Targets via Whole Exome Sequencing and CRISPR-Cas9', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, ELECTR NETWORK, Vol. 35, pp. 22 - 22, presented at Annual Meeting of the American-Society-for-Bone-and Mineral Research (ASBMR), ELECTR NETWORK, 11 September 2020 - 15 September 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000593119300060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Morris J; Kemp J; Youlten S; Logan J; Chai R; Vulpescu N; Forgetta V; Kleinman A; Mohanty S; Sergio M; Medina-Gomez C; Trajanoska K; Quinn J; Ghirardello E; Butterfield N; Curry K; Leitch V; Sparkes P; Laurent L; Adoum A-T; Mannan N; Komla-Ebri D; Pollard A; Dewhurst H; Kaptoge S; Baldock P; Cooper C; Reeve J; Ntzani E; Evangelou E; Ohlsson C; Karasik D; Rivadeneira F; Ackert-Bicknell C; Kiel D; Tobias J; Gregson C; Harvey N; Adams D; Lelliott C; Hinds D; Hsu Y-H; Maurano M; Croucher P; Williams G; Bassett D; Evans D; Richards B, 2018, 'An Atlas of Human and Murine Genetic Influences on Osteoporosis', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, Montreal, CANADA, Vol. 33, pp. 105 - 105, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Montreal, CANADA, 28 September 2018 - 01 October 2018, http://dx.doi.org/10.1002/jbmr.3621

Gregson C; Newell F; Leo P; Paternoster L; Marshall M; Clark G; Morris J; Ge B; Bao X; Bassett D; Williams G; Youlten S; Croucher P; Smith GD; Evans D; Kemp J; Brown M; Tobias J; Duncan E, 2017, 'Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypes.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, CO, Denver, Vol. 32, pp. S207 - S207, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), CO, Denver, 08 September 2017 - 11 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418869202136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McDonald M; Ng PY; Butt D; Pathmanandavel K; Biro M; Terry R; Khoo WH; Mohanty S; Simic M; Chai R; Quinn J; Pettitt J; Abi-Hanna D; Jain R; Weninger W; Baldock P; Rogers M; Brink R; Pavlos N; Croucher P; Phan T, 2017, 'Intravital imaging of osteoclasts in vivo reveals cellular recycling as a novel cell fate mechanism.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, CO, Denver, Vol. 32, pp. S37 - S37, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), CO, Denver, 08 September 2017 - 11 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418869200110&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Youlten S; Baldock P; Leitch V; Quinn J; Bartonicek N; Chai R; Eisman J; Bassett JHD; Williams G; Croucher P, 2017, 'Osteocytes express a unique transcriptome that underpins skeletal homeostasis.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, CO, Denver, Vol. 32, pp. S55 - S56, presented at Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), CO, Denver, 08 September 2017 - 11 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418869200166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Eisman J; Croucher P; Baldock P; Nguyen T; Brink R; Hesselson D; Nguyen S; Moni M; Youlten S, 2017, 'Identification of anabolic bone genes using whole genome sequencing in high bone mass families.', in JOURNAL OF BONE AND MINERAL RESEARCH, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, Vol. 32, pp. S71 - S71, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA

Byrne NM; Khoo WH; Mourad N; Quinn JAPJ; Shah S; Mcdonald MM; Cazet A; Swarbrick A; Phan TG; Rogers MJ; Croucher PI, 2016, 'Identification of dormant prostate cancer cells in the skeleton in vivo and ex vivo', in BJU INTERNATIONAL, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 118, pp. 35 - 36, presented at 17th Asia-Pacific Prostate Cancer Conference, AUSTRALIA, Melbourne, 31 August 2016 - 03 September 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000381708200082&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McDonald M; Butt D; Terry R; Quinn J; Rogers M; Brink R; Croucher P; Phan T, 2016, 'Real-time intravital longitudinal imaging of osteoclast formation, function and fate during bone remodeling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 270 - 270, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400545&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Reagan MR; McDonald M; Terry R; Pettitt J; Le L; Mohanty S; Kneissel M; Kramer I; Brooks D; Bouxsein M; Rosen CJ; Ghobrial IM; Croucher P, 2015, 'Anti-Sclerostin Treatment Prevents Multiple Myeloma Induced Bone Loss and Reduces Tumor Burden', in Blood, American Society of Hematology, Vol. 126, pp. 119, http://dx.doi.org/10.1182/blood.v126.23.119.119

Preprints

Clark JR; Panagopoulos V; Noll JE; Mrozik KM; Bradey AL; Croucher PI; Zannettino ACW; Vandyke K; Hewett DR, 2024, Mer receptor expression promotes multiple myeloma disease development via a cell-extrinsic mechanism, http://dx.doi.org/10.21203/rs.3.rs-4166577/v1

Gregson CL; Bergen D; Leo P; Sessions RB; Wheeler L; Hartley A; Youlten S; Croucher PI; McInerney-Leo AM; Fraser W; Tang JCY; Anderson L; Marshall M; Sergot L; Paternoster L; Davey-Smith G; Consortium TA; Brown MA; Hammond C; Kemp JP; Tobias JH; Duncan EL, A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target, http://dx.doi.org/10.1101/560565

Butterfield NC; Curry KF; Steinberg J; Dewhurst H; Komla-Ebri D; Mannan NS; Adoum A-T; Leitch VD; Logan JG; Waung JA; Ghirardello E; Southam L; Youlten SE; Wilkinson JM; McAninch EA; Vancollie VE; Kussy F; White JK; Lelliott CJ; Adams DJ; Jacques R; Bianco AC; Boyde A; Zeggini E; Croucher PI; Williams GR; Bassett JHD, Accelerating functional gene discovery in osteoarthritis, http://dx.doi.org/10.1101/836221

Morris JA; Kemp JP; Youlten SE; Laurent L; Logan JG; Chai R; Vulpescu NA; Forgetta V; Kleinman A; Mohanty S; Sergio CM; Quinn J; Nguyen-Yamamoto L; Luco AL; Vijay J; Simon M-M; Pramatarova A; Medina-Gomez C; Trajanoska K; Ghirardello EJ; Butterfield NC; Curry KF; Leitch VD; Sparkes PC; Adoum A-T; Mannan NS; Komla-Ebri D; Pollard AS; Dewhurst HF; Hassall T; Beltejar M-JG; Adams DJ; Vaillancourt SM; Kaptoge S; Baldock P; Cooper C; Reeve J; Ntzani E; Evangelou E; Ohlsson C; Karasik D; Rivadeneira F; Kiel DP; Tobias JH; Gregson CL; Harvey NC; Grundberg E; Goltzman D; Adams DJ; Lelliott CJ; Hinds DA; Ackert-Bicknell CL; Hsu Y-H; Maurano MT; Croucher PI; Williams GR; Bassett JHD; Evans DM; Richards JB, An Atlas of Human and Murine Genetic Influences on Osteoporosis, http://dx.doi.org/10.1101/338863

Khoo WH; Jackson K; Phetsouphanh C; Zaunders JJ; Alquicira-Hernandez J; Yazar S; Ruiz-Diaz S; Singh M; Dhenni R; Kyaw W; Tea F; Merheb V; Lee FXZ; Burrell R; Howard-Jones A; Koirala A; Zhou L; Yuksel A; Catchpoole DR; Lai CL; Vitagliano TL; Rouet R; Christ D; Tang B; West NP; George S; Gerrard J; Croucher PI; Kelleher AD; Goodnow CG; Sprent JD; Powell JD; Brilot F; Nanan R; Hsu PS; Deenick EK; Britton PN; Phan TG, Clonal dynamics of SARS-CoV-2-specific T cells in children and adults with COVID-19, http://dx.doi.org/10.1101/2022.01.30.478400

Kyaw W; Chai RC; Khoo WH; Goldstein LD; Croucher PI; Murray JM; Phan TG, ENTRAIN: integrating trajectory inference and gene regulatory networks with spatial data to co-localize the receptor-ligand interactions that specify cell fate, http://dx.doi.org/10.1101/2023.07.09.548284

Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks ML; Law H; Danwilai T; Starr M; Munier CML; Christ D; Singh M; Croucher PI; Brilot-Turville F; Turville S; Phan TG; Dore GJ; Darley D; Cunningham P; Matthews GV; Kelleher AD; Zaunders JJ, High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells, http://dx.doi.org/10.1101/2022.07.22.22277947

Chai RC; Lundberg M; Freudenthal B; Smith JT; Boughton AP; Zhang Y; Flynn KA; Frysz M; Corr AP; Khoo WH; Komla-Ebri D; Dack MRG; Guilfoyle SE; Logan JG; Butterfield NC; Leitch VD; Pollard AS; Mäkitie RE; Bradford N; Ramos-Mucci L; Vilas-Zornoza A; Chen Y; Yip RKH; Er J; Tan SZ; McDonald MM; Youlten SE; Sergio CM; Castro-Martinez A; Young SG; Skorokhodova E; Evans DM; Powell JE; de Leeuw CA; Ewing AD; Eisman JA; Blank RD; Phan TG; Group IFOMRSBDW; Lagendijk AK; Hawkins ED; Oh HL; McIntyre R; Hessel EM; Taylor-King JP; Baldock PA; Duncan EL; Williams GR; Bassett JHD; Croucher PI; Kemp JP, Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease, http://dx.doi.org/10.1101/2024.12.16.628792

Youlten SE; Kemp JP; Logan JG; Ghirardello EJ; Sergio CM; Dack MRG; Guilfoyle SE; Leitch VD; Butterfield NC; Komla-Ebri D; Chai RC; Corr AP; Smith JT; Mohanty S; Morris JA; McDonald MM; Quinn JMW; McGlade AR; Bartonicek N; Jansson M; Hatzikotoulas K; Irving MD; Beleza-Meireles A; Rivadeneira F; Duncan E; Richards JB; Adams DJ; Lelliott CJ; Brink R; Phan TG; Eisman JA; Evans DM; Zeggini E; Baldock PA; Bassett JHD; Williams GR; Croucher PI, Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease, http://dx.doi.org/10.1101/2020.04.20.051409

Gration B; Chai RC; Young SG; Sergio CM; Skorokhodova E; Smith JT; Castro-Martinez A; Bray A; Lin X; Yan C; Kao J; Perram J; Lai S; Lau L; Weilbaecher KN; Moore J; Pocock N; Chaffer CL; Center J; Phan TG; McCaughan G; Croucher PI, Romosozumab Safely Restores Bone Mass in Multiple Myeloma via Osteoblast Reprogramming: A Phase IIa Study, http://dx.doi.org/10.64898/2026.07.02.26357196

Bergen DJM; Tong Q; Shukla A; Newman E; Zethof J; Lundberg M; Ryan R; Youlten SE; Zeggini E; Croucher PI; Flik G; Richardson RJ; Kemp JP; Hammond CL; Metz JR, The transcriptome of regenerating zebrafish scales identifies genes involved in human bone disease, http://dx.doi.org/10.1101/2020.10.08.331561

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