By Professor Richard John Epstein

Books

Epstein RJ, 2003, Human Molecular Biology An Introduction to the Molecular Basis of Health and Disease, Cambridge University Press

Epstein R, 2003, medicine for examinations

Book Chapters

Epstein RJ; Todd D, 2006, 'Professionalism', in Problem-Based Medical Case Management, pp. 271 - 279

Epstein RJ; Henderson IC, 1993, 'Chemotherapy for Node-Negative Breast Cancer', in Non-Disseminated Breast Cancer, Springer Berlin Heidelberg, pp. 43 - 56, http://dx.doi.org/10.1007/978-3-642-84593-2_6

Journal articles

Tan E; Lim S; Lamont D; Epstein R; Lim D; Lin FPY, 2024, 'Development and validation of a deep learning model for improving detection of nonmelanoma skin cancers treated with Mohs micrographic surgery', JAAD International, 14, pp. 39 - 47, http://dx.doi.org/10.1016/j.jdin.2023.10.007

Lin FP-Y; Joshua AM; Epstein RJ, 2023, 'Machine learning prediction of patient-reported outcomes associated with systemic therapy from medical records.', Journal of Clinical Oncology, 41, pp. e13564 - e13564, http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e13564

Tempero MA; Pelzer U; O'Reilly EM; Winter J; Oh DY; Li CP; Tortora G; Chang HM; Lopez CD; Bekaii-Saab T; Ko AH; Santoro A; Park JO; Noel MS; Frassineti GL; Shan YS; Dean A; Riess H; Van Cutsem E; Berlin J; Philip P; Moore M; Goldstein D; Tabernero J; Li M; Ferrara S; Le Bruchec Y; Zhang G; Lu B; Biankin AV; Reni M; Epstein R; Vasey P; Shapiro J; Burge M; Chua YJ; Harris M; Pavlakis N; Tebbutt N; Prager G; Dittrich C; Längle F; Philipp-Abbrederis K; Greil R; Stöger H; Girschikofsky M; Kuehr T; Van Laethem JL; Laurent S; Dhani N; Ko YJ; Dowden S; Kavan P; Tehfe MÉ; Kubala E; Kohoutek M; Pfeiffer P; Yilmaz M; Parner V; Salminen T; Soveri LM; Korkeila E; Osterlund P; Taieb J; Tougeron D; Artru P; Caroli-Bosc FX; Guimbaud R; Turpin A; Walter T; Bachet JB; Kunzmann V; Kreth F; Block A; Venerito M; Oettle H; Karthaus M; Trojan J; Folprecht G; Lerch M; Kullmann F; Reiser M; Heinemann V; Wörns MA; Schulz H; Garlipp B; Yau T; Chan LS; Juhasz B; Landherr L; Pinter T; Bodoky G; Kahán Z; McDermott R; Power D; Gianni L; Siena S; Milella M; Falcone A; Berardi R, 2023, 'Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results from a Randomized, Open-Label, Phase III Trial', Journal of Clinical Oncology, 41, pp. 2007 - 2019, http://dx.doi.org/10.1200/JCO.22.01134

Epstein RJ; Lin FPY; Brink RA; Blackburn J, 2023, 'Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice', PLoS ONE, 18, http://dx.doi.org/10.1371/journal.pone.0284327

Epstein RJ; Gu Y; Lin FPY, 2023, 'Can cancer go green? It’s up to us', Frontiers in Oncology, 13, http://dx.doi.org/10.3389/fonc.2023.1074091

Epstein RJ, 2023, 'To find fault is easy, to find no-fault is fair.', Future Healthc J, 10, pp. 85 - 89, http://dx.doi.org/10.7861/fhj.2022-0049

Po-Yen Lin F; Salih OSM; Scott N; Jameson MB; Epstein RJ, 2022, 'Development and Validation of a Machine Learning Approach Leveraging Real-World Clinical Narratives as a Predictor of Survival in Advanced Cancer', JCO clinical cancer informatics, 6, pp. e2200064, http://dx.doi.org/10.1200/CCI.22.00064

Epstein RJ, 2021, 'The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor', Tumor Biology, 43, pp. 159 - 176, http://dx.doi.org/10.3233/TUB-211502

Epstein RJ; Tian LJ; Gu YF, 2021, '2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology', Journal of Oncology, 2021, http://dx.doi.org/10.1155/2021/9955456

Gu YF; Lin FP; Epstein RJ, 2021, 'How aging of the global population is changing oncology', ecancermedicalscience, 15, http://dx.doi.org/10.3332/ecancer.2021.ed119

Lami H; Epstein RJ; Cherepanoff S; Conway RM, 2020, 'Effective conservative management of locally advanced conjunctival melanoma using initial systemic therapy', Clinical and Experimental Ophthalmology, 48, pp. 402 - 404, http://dx.doi.org/10.1111/ceo.13691

Sternberg CN; Saad F; Graff JN; Peer A; Vaishampayan UN; Leung E; Rosenbaum E; Gurney H; Epstein RJ; Davis ID; Wu B; Trandafir L; Wagner VJ; Hussain M, 2020, 'A randomised phase II trial of three dosing regimens of radium-223 in patients with bone metastatic castration-resistant prostate cancer', Annals of Oncology, 31, pp. 257 - 265, http://dx.doi.org/10.1016/j.annonc.2019.10.025

Vasista A; Stockler M; Martin A; Pavlakis N; Sjoquist K; Goldstein D; Gill S; Jain V; Liu G; Kannourakis G; Kim YH; Nott L; Snow S; Burge M; Harris D; Jonker D; Chua YJ; Epstein R; Bonaventura A; Kiely B, 2019, 'Accuracy and Prognostic Significance of Oncologists’ Estimates and Scenarios for Survival Time in Advanced Gastric Cancer', Oncologist, 24, pp. e1102 - e1107, http://dx.doi.org/10.1634/theoncologist.2018-0613

Lin FP-Y; Jameson MB; Epstein RJ, 2019, 'Predicting survival in advanced cancers by applying machine learning to clinical narratives.', Journal of Global Oncology, 5, pp. 32 - 32, http://dx.doi.org/10.1200/jgo.2019.5.suppl.32

Young FP; Ende D; Epstein RJ, 2019, 'Beyond BCG: The approaching era of personalised bladder-sparing therapies for non-muscle-invasive urothelial cancers', Future Oncology, 15, pp. 409 - 420, http://dx.doi.org/10.2217/fon-2018-0565

Emmett L; Crumbaker M; Ho B; Willowson K; Eu P; Ratnayake L; Epstein R; Blanksby A; Horvath L; Guminski A; Mahon K; Gedye C; Yin C; Stricker P; Joshua AM, 2019, 'Results of a Prospective Phase 2 Pilot Trial of ¹⁷⁷ Lu–PSMA-617 Therapy for Metastatic Castration-Resistant Prostate Cancer Including Imaging Predictors of Treatment Response and Patterns of Progression', Clinical Genitourinary Cancer, 17, pp. 15 - 22, http://dx.doi.org/10.1016/j.clgc.2018.09.014

Emmett L; Yin C; Crumbaker M; Hruby G; Kneebone A; Epstein R; Nguyen Q; Hickey A; Ihsheish N; O'Neill G; Horvath L; Chalasani V; Stricker P; Joshua AM, 2019, 'Rapid modulation of PSMA expression by androgen deprivation: Serial ⁶⁸Ga-PSMA-11 PET in men with hormone-sensitive and castrate-resistant prostate cancer commencing androgen blockade', Journal of Nuclear Medicine, 60, pp. 950 - 954, http://dx.doi.org/10.2967/jnumed.118.223099

Francis PA; Pagani O; Fleming GF; Walley BA; Colleoni M; Láng I; Gómez HL; Tondini C; Ciruelos E; Burstein HJ; Bonnefoi HR; Bellet M; Martino S; Geyer CE; Goetz MP; Stearns V; Pinotti G; Puglisi F; Spazzapan S; Climent MA; Pavesi L; Ruhstaller T; Davidson NE; Coleman R; Debled M; Buchholz S; Ingle JN; Winer EP; Maibach R; Rabaglio-Poretti M; Ruepp B; Di Leo A; Coates AS; Gelber RD; Goldhirsch A; Regan MM; SOFT and TEXT Investigators and the International Breast Cancer Study Group , 2018, 'Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.', N Engl J Med, 379, pp. 122 - 137, http://dx.doi.org/10.1056/NEJMoa1803164

Smith MR; Saad F; Chowdhury S; Oudard S; Hadaschik BA; Graff JN; Olmos D; Mainwaring PN; Lee JY; Uemura H; Lopez-Gitlitz A; Trudel GC; Espina BM; Shu Y; Park YC; Rackoff WR; Yu MK; Small EJ, 2018, 'Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer', New England Journal of Medicine, 378, pp. 1408 - 1418, http://dx.doi.org/10.1056/nejmoa1715546

Lin FP; Epstein RJ; Groza T; Kocbek S; Antezana E, 2018, 'Cancer care treatment outcome ontology: A novel computable ontology for profiling treatment outcomes in patients with solid tumors', JCO Clinical Cancer Informatics, 2018, pp. 1 - 14, http://dx.doi.org/10.1200/CCI.18.00026

Lin FPY; Pokorny A; Teng C; Epstein RJ, 2017, 'TEPAPA: A novel in silico feature learning pipeline for mining prognostic and associative factors from text-based electronic medical records', Scientific Reports, 7, pp. 6918, http://dx.doi.org/10.1038/s41598-017-07111-0

Fazekas-Lavu M; Parker A; Spigelman AD; Scott RJ; Epstein RJ; Jensen M; Samaras K, 2017, 'Thyroid cancer in a patient with lynch syndrome – case report and literature review', Therapeutics and Clinical Risk Management, 13, pp. 915 - 918, http://dx.doi.org/10.2147/TCRM.S121812

Epstein RJ; Lin FP, 2017, 'Cancer and the omics revolution', Australian Family Physician, 46, pp. 189 - 193

Vasista A; Martin A; Pavlakis N; Sjoquist K; Snow S; Jonker D; Chua YJ; Epstein R; Bonaventura A; Khasraw M; Varma SC; Singhal N; Ransom DT; Aubin F; Burkes R; Lim H; Lemay F; Begbie S; Stockler MR; Kiely B, 2017, 'Accuracy and prognostic significance of oncologists’ estimates and scenarios for survival time in a randomised Phase 2 trial of regorafenib in advanced gastric cancer', Annals of Oncology, 28, pp. v226 - v227, http://dx.doi.org/10.1093/annonc/mdx369.050

Epstein RJ, 2016, 'Be careful what you wish for', Medical Journal of Australia, 205, pp. 521 - 522.e1, http://dx.doi.org/10.5694/MJA16.00836

Lin FPY; Pokorny A; Teng C; Dear R; Epstein RJ, 2016, 'Computational prediction of multidisciplinary team decision-making for adjuvant breast cancer drug therapies: A machine learning approach', BMC Cancer, 16, pp. 929, http://dx.doi.org/10.1186/s12885-016-2972-z

Blackburn J; Roden DL; Ng R; Wu J; Bosman A; Epstein RJ, 2016, 'Damage-inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter', Molecular Carcinogenesis, 55, pp. 1940 - 1951, http://dx.doi.org/10.1002/mc.22441

Choueiri TK; Escudier B; Powles T; Mainwaring PN; Rini BI; Donskov F; Hammers H; Hutson TE; Lee J-L; Peltola K; Roth BJ; Bjarnason GA; Géczi L; Keam B; Maroto P; Heng DYC; Schmidinger M; Kantoff PW; Borgman-Hagey A; Hessel C; Scheffold C; Schwab GM; Tannir NM; Motzer RJ; METEOR Investigators , 2015, 'Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.', N Engl J Med, 373, pp. 1814 - 1823, http://dx.doi.org/10.1056/NEJMoa1510016

Zheng S; Chan H; Epstein RJ; Joseph JE, 2015, 'Resolution of paraneoplastic immune thrombocytopenia following everolimus treatment for metastatic renal cell carcinoma', Internal Medicine Journal, 45, pp. 666 - 669, http://dx.doi.org/10.1111/imj.12779

Epstein RJ, 2015, 'A periodic table for cancer', Future Oncology, 11, pp. 785 - 800, http://dx.doi.org/10.2217/fon.14.315

Francis PA; Regan MM; Fleming GF; Láng I; Ciruelos E; Bellet M; Bonnefoi HR; Climent MA; Da Prada GA; Burstein HJ; Martino S; Davidson NE; Geyer CE; Walley BA; Coleman R; Kerbrat P; Buchholz S; Ingle JN; Winer EP; Rabaglio-Poretti M; Maibach R; Ruepp B; Giobbie-Hurder A; Price KN; Colleoni M; Viale G; Coates AS; Goldhirsch A; Gelber RD; SOFT Investigators ; International Breast Cancer Study Group , 2015, 'Adjuvant ovarian suppression in premenopausal breast cancer.', N Engl J Med, 372, pp. 436 - 446, http://dx.doi.org/10.1056/NEJMoa1412379

Epstein RJ, 2015, 'PERSONAL VIEW "By the way doctor, I've booked an African safari after my next chemo"', BMJ-BRITISH MEDICAL JOURNAL, 350, http://dx.doi.org/10.1136/bmj.g7822

Ding P; Tai J; Manders P; Stone E; Ho B; Epstein R, 2015, '500P Dependence of fluorodeoxyglucose avidity on tumour size in non-small cell lung cancer', Annals of Oncology, 26, pp. ix153 - ix153, http://dx.doi.org/10.1093/annonc/mdv534.04

Wong H; Lau S; Cheung P; Wong TT; Parker A; Yau T; Epstein RJ, 2014, 'Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: Implications for tumor biology and adjuvant therapy', BMC Cancer, 14, http://dx.doi.org/10.1186/1471-2407-14-826

Pagani O; Regan MM; Walley BA; Fleming GF; Colleoni M; Láng I; Gomez HL; Tondini C; Burstein HJ; Perez EA; Ciruelos E; Stearns V; Bonnefoi HR; Martino S; Geyer CE; Pinotti G; Puglisi F; Crivellari D; Ruhstaller T; Winer EP; Rabaglio-Poretti M; Maibach R; Ruepp B; Giobbie-Hurder A; Price KN; Bernhard J; Luo W; Ribi K; Viale G; Coates AS; Gelber RD; Goldhirsch A; Francis PA; TEXT and SOFT Investigators ; International Breast Cancer Study Group , 2014, 'Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.', N Engl J Med, 371, pp. 107 - 118, http://dx.doi.org/10.1056/NEJMoa1404037

Zhang Q; Leung R; Wong H; Chiu J; Chu KW; Poon J; Epstein RJ; Kwong YL; Yau T, 2014, 'Comparison of cetuximab and bevacizumab as first-line treatment in KRAS wild type advanced colorectal cancer patients: a retrospective analysis', EUROPEAN JOURNAL OF CANCER, 50, pp. S12 - S12, http://dx.doi.org/10.1016/S0959-8049(14)70040-1

Connolly K; Manders P; Earls P; Epstein RJ, 2014, 'Papillomavirus-associated squamous skin cancers following transplant immunosuppression: One Notch closer to control', Cancer Treatment Reviews, 40, pp. 205 - 214, http://dx.doi.org/10.1016/j.ctrv.2013.08.005

Connolly K; Brungs D; Szeto E; Epstein RJ, 2014, 'Anticancer activity of combination targeted therapy using cetuximab plus vemurafenib for refractory BRAF^V600E-mutant metastatic colorectal carcinoma', Current Oncology, 21, http://dx.doi.org/10.3747/co.21.1661

Quah XM; Conway RM; Madigan MC; Epstein RJ, 2014, 'Emerging strategies for therapeutic targeting of the tumour microenvironment', Cancer Forum, 38, pp. 133 - 137

Brungs D; Chen J; Masson P; Epstein RJ, 2014, 'Intermittent androgen deprivation is a rational standard-of-care treatment for all stages of progressive prostate cancer: Results from a systematic review and meta-analysis', Prostate Cancer and Prostatic Diseases, 17, pp. 105 - 111, http://dx.doi.org/10.1038/pcan.2014.10

Epstein RJ, 2013, 'The unpluggable in pursuit of the undruggable: Tackling the dark matter of the cancer therapeutics universe', Frontiers in Oncology, 3 DEC, http://dx.doi.org/10.3389/fonc.2013.00304

Epstein RJ, 2013, 'Has discovery-based cancer research been a bust?', Clinical and Translational Oncology, 15, pp. 865 - 870, http://dx.doi.org/10.1007/s12094-013-1071-8

Zhao Y; Epstein RJ, 2013, 'Conserved nonsense-prone CpG sites in apoptosis-regulatory genes: Conditional stop signs on the road to cell death', Evolutionary Bioinformatics, 2013, pp. 275 - 283, http://dx.doi.org/10.4137/EBO.S11759

Epstein CR; Epstein RJ, 2013, 'Death in The New York Times: the price of fame is a faster flame', QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 106, pp. 517 - 521, http://dx.doi.org/10.1093/qjmed/hct077

Chiu J; Tang V; Leung R; Wong H; Chu KW; Poon J; Epstein RJ; Yau T, 2013, 'Efficacy and tolerability of adjuvant oral capecitabine plus intravenous oxaliplatin (XELOX) in Asian patients with colorectal cancer: 4-year analysis', Asian Pacific Journal of Cancer Prevention, 14, pp. 6585 - 6590, http://dx.doi.org/10.7314/APJCP.2013.14.11.6585

Brungs D; Sze V; Emmett L; Epstein RJ, 2013, 'Complete Radiologic Response of Bulky Cerebral Metastases From Newly Diagnosed HER2-Positive Breast Cancer to Upfront Trastuzumab-Based Chemotherapy.', World J Oncol, 4, pp. 122 - 125, http://dx.doi.org/10.4021/wjon639w

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