By Professor Robert Bruce Gilchrist

Journal articles

Brown HM; Anastasi MR; Frank LA; Kind KL; Richani D; Robker RL; Russell DL; Gilchrist RB; Thompson JG, 2015, 'Hemoglobin: A gas transport molecule that is hormonally regulated in the ovarian follicle in mice and humans', Biology of Reproduction, 92, http://dx.doi.org/10.1095/biolreprod.114.124594

Li JJ; Sugimura S; Mueller TD; White MA; Martin GA; Ritter LJ; Liang XY; Gilchrist RB; Mottershead DG, 2015, 'Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes', Molecular Endocrinology, 29, pp. 40 - 52, http://dx.doi.org/10.1210/me.2014-1173

Mester B; Ritter LJ; Pitman JL; Bibby AH; Gilchrist RB; McNatty KP; Juengel JL; McIntosh CJ, 2015, 'Oocyte expression, secretion and somatic cell interaction of mouse bone morphogenetic protein 15 during the peri-ovulatory period', Reproduction, Fertility and Development, 27, pp. 801 - 811, http://dx.doi.org/10.1071/RD13336

Gilchrist RB; Zeng HT; Wang X; Richani D; Smitz J; Thompson JG, 2015, 'Reevaluation and evolution of the simulated physiological oocyte maturation system', Theriogenology, http://dx.doi.org/10.1016/j.theriogenology.2015.03.032

Sugimura S; Ritter LJ; Rose RD; Thompson JG; Mottershead DG; Gilchrist RB, 2014, 'BMP15 plus GDF9 and cAMP modulator promote EGF receptor signaling to increase oocyte developmental competence in porcine cumulus-oocyte complexes from small follicles', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p125

Rose RD; Sugimura S; Ritter LJ; Brown HM; Thompson JG; Gilchrist RB, 2014, 'C-type natriuretic peptide stimulates resumption of meiosis via a cGMP-dependant mechanism in porcine oocytes', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p034

Nogueira MG; Machado MF; Li H; Razza EM; Gilchrist RB; Sutton-McDowall ML; Thompson JG, 2014, 'Effect of cAMP regulators on bovine cumulus-oocyte communication and embryo development in vitro', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p043

Santiquet N; Sasseville M; Laforest M; Guillemette C; Gilchrist RB; Richard FJ, 2014, 'Activation of 5' adenosine monophosphate-activated protein kinase blocks cumulus cell expansion through inhibition of protein synthesis during in vitro maturation in swine', Biology of Reproduction, 91, http://dx.doi.org/10.1095/biolreprod.113.116764

Zeng HT; Richani D; Sutton-McDowall ML; Ren Z; Smitz JEJ; Stokes Y; Gilchrist RB; Thompson JG, 2014, 'Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro- matured mouse oocytes', Biology of Reproduction, 91, http://dx.doi.org/10.1095/biolreprod.114.118471

Sudiman J; Sutton-McDowall ML; Ritter LJ; White MA; Mottershead DG; Thompson JG; Gilchrist RB, 2014, 'Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence', PLoS ONE, 9, pp. e103563, http://dx.doi.org/10.1371/journal.pone.0103563

Sugimura S; Ritter LJ; Sutton-McDowall ML; Mottershead DG; Thompson JG; Gilchrist RB, 2014, 'Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: Effects on gap junction-mediated metabolite supply', Molecular Human Reproduction, 20, pp. 499 - 513, http://dx.doi.org/10.1093/molehr/gau013

Simpson CM; Robertson DM; Al-Musawi SL; Heath DA; McNatty KP; Ritter LJ; Mottershead DG; Gilchrist RB; Harrison CA; Stanton PG, 2014, 'Aberrant GDF9 expression and activation are associated with common human ovarian disorders', Journal of Clinical Endocrinology and Metabolism, 99, http://dx.doi.org/10.1210/jc.2013-3949

Richani D; Sutton-McDowall ML; Frank LA; Gilchrist RB; Thompson JG, 2014, 'Effect of epidermal growth factor-like peptides on the metabolism of in vitro-matured mouse oocytes and cumulus cells', Biology of Reproduction, 90, http://dx.doi.org/10.1095/biolreprod.113.115311

Sudiman J; Ritter LJ; Feil DK; Wang X; Chan K; Mottershead DG; Robertson DM; Thompson JG; Gilchrist RB, 2014, 'Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development', Journal of Assisted Reproduction and Genetics, 31, pp. 295 - 306, http://dx.doi.org/10.1007/s10815-013-0152-5

Frank LA; Sutton-Mcdowall ML; Brown HM; Russell DL; Gilchrist RB; Thompson JG, 2014, 'Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of Heat shock protein 90', Human Reproduction, 29, pp. 1292 - 1303, http://dx.doi.org/10.1093/humrep/deu066

Richani D; Wang X; Zeng HT; Smitz J; Thompson JG; Gilchrist RB, 2014, 'Pre-maturation with cAMP modulators in conjunction with EGF-like peptides during in vitro maturation enhances mouse oocyte developmental competence', Molecular Reproduction and Development, 81, pp. 422 - 435, http://dx.doi.org/10.1002/mrd.22307

Frank LA; Sutton-Mcdowall ML; Gilchrist RB; Thompson JG, 2014, 'The effect of peri-conception hyperglycaemia and the involvement of the hexosamine biosynthesis pathway in mediating oocyte and embryo developmental competence', Molecular Reproduction and Development, 81, pp. 391 - 408, http://dx.doi.org/10.1002/mrd.22299

Machado MF; Nogueira MF; Gilchrist RB; Sutton-McDowall ML; Mottershead DG; White MA; Thompson JG, 2014, '236 effect of cyclic adenosine monophosphate modulator regulators in association with bmp15 on bovine embryo development in vitro.', Reprod Fertil Dev, 27, pp. 207 - 208, http://dx.doi.org/10.1071/RDv27n1Ab236

Gilchrist RB; Richani D, 2013, 'Somatic guidance for the oocyte', Developmental Cell, 27, pp. 603 - 605, http://dx.doi.org/10.1016/j.devcel.2013.12.006

Thompson JG; Gilchrist RB, 2013, 'Pioneering contributions by Robert Edwards to oocyte in vitro maturation (IVM)', Molecular Human Reproduction, 19, pp. 794 - 798, http://dx.doi.org/10.1093/molehr/gat075

Frank LA; Sutton-Mcdowall ML; Russell DL; Wang X; Feil DK; Gilchrist RB; Thompson JG, 2013, 'Effect of varying glucose and glucosamine concentration in vitro on mouse oocyte maturation and developmental competence', Reproduction, Fertility and Development, 25, pp. 1095 - 1104, http://dx.doi.org/10.1071/RD12275

Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2013, 'Mode of oocyte maturation affects EGF-like peptide function and oocyte competence', Molecular Human Reproduction, 19, pp. 500 - 509, http://dx.doi.org/10.1093/molehr/gat028

Caixeta ES; Sutton-McDowall ML; Gilchrist RB; Thompson JG; Price CA; Machado MF; Lima PF; Buratini J, 2013, 'Bone morphogenetic protein 15 and fibroblast growth factor 10 enhance cumulus expansion, glucose uptake, and expression of genes in the ovulatory cascade during in vitro maturation of bovine cumulus-oocyte complexes', Reproduction, 146, pp. 27 - 35, http://dx.doi.org/10.1530/REP-13-0079

Mottershead DG; Harrison CA; Mueller TD; Stanton PG; Gilchrist RB; McNatty KP, 2013, 'Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization', Proceedings of the National Academy of Sciences of the United States of America, 110, http://dx.doi.org/10.1073/pnas.1303459110

Thompson JG; Mottershead DG; Gilchrist RB, 2013, 'Oocyte-Secreted Factors in Domestic Animals', , pp. 55 - 70, http://dx.doi.org/10.1002/9781118538074.ch4

Zeng HT; Ren Z; Guzman L; Wang X; Sutton-Mcdowall ML; Ritter LJ; De Vos M; Smitz J; Thompson JG; Gilchrist RB, 2013, 'Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence', Human Reproduction, 28, pp. 1536 - 1545, http://dx.doi.org/10.1093/humrep/det086

Rose RD; Gilchrist RB; Kelly JM; Thompson JG; Sutton-McDowall ML, 2013, 'Regulation of sheep oocyte maturation using cAMP modulators', Theriogenology, 79, pp. 142 - 148, http://dx.doi.org/10.1016/j.theriogenology.2012.09.020

Sutton-Mcdowall ML; Mottershead DG; Gardner DK; Gilchrist RB; Thompson JG, 2012, 'Metabolic differences in bovine cumulus-oocyte complexes matured in vitro in the presence or absence of follicle-stimulating hormone and bone morphogenetic protein 15', Biology of Reproduction, 87, http://dx.doi.org/10.1095/biolreprod.112.102061

Watson LN; Mottershead DG; Dunning KR; Robker RL; Gilchrist RB; Russell DL, 2012, 'Heparan sulfate proteoglycans regulate responses to oocyte paracrine signals in ovarian follicle morphogenesis', Endocrinology, 153, pp. 4544 - 4555, http://dx.doi.org/10.1210/en.2012-1181

Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2012, 'Consequences of In Vitro Maturation of Oocytes on Cumulus Cell EGF-Like Peptide Signaling.', Biology of Reproduction, 87, pp. 365 - 365, http://dx.doi.org/10.1093/biolreprod/87.s1.365

Sharkey DJ; Macpherson AM; Tremellen KP; Mottershead DG; Gilchrist RB; Robertson SA, 2012, 'TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells', Journal of Immunology, 189, pp. 1024 - 1035, http://dx.doi.org/10.4049/jimmunol.1200005

Voudouris V; Gilchrist R; Rigby R; Sedgwick J; Stasinopoulos D, 2012, 'Modelling skewness and kurtosis with the BCPE density in GAMLSS', Journal of Applied Statistics, 39, pp. 1279 - 1293, http://dx.doi.org/10.1080/02664763.2011.644530

Simpson CM; Stanton PG; Walton KL; Chan KL; Ritter LJ; Gilchrist RB; Harrison CA, 2012, 'Activation of latent human GDF9 by a single residue change (Gly ³⁹¹Arg) in the mature domain', Endocrinology, 153, pp. 1301 - 1310, http://dx.doi.org/10.1210/en.2011-1632

Mottershead DG; Ritter LJ; Gilchrist RB, 2012, 'Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15', Molecular Human Reproduction, 18, pp. 121 - 128, http://dx.doi.org/10.1093/molehr/gar056

Gilchrist RB; Ritter LJ, 2011, 'Differences in the participation of TGFB superfamily signalling pathways mediating porcine and murine cumulus cell expansion', Reproduction, 142, pp. 647 - 657, http://dx.doi.org/10.1530/REP-11-0196

Gilchrist RB; De Vos M; Smitz J; Thompson JG, 2011, 'IVM media are designed specifically to support immature cumulus-oocyte complexes not denuded oocytes that have failed to respond to hyperstimulation', Fertility and Sterility, 96, http://dx.doi.org/10.1016/j.fertnstert.2011.06.012

Scaramuzzi RJ; Baird DT; Campbell BK; Driancourt MA; Dupont J; Fortune JE; Gilchrist RB; Martin GB; McNatty KP; McNeilly AS; Monget P; Monniaux D; Viñoles C; Webb R, 2011, 'Regulation of folliculogenesis and the determination of ovulation rate in ruminants', Reproduction, Fertility and Development, 23, pp. 444 - 467, http://dx.doi.org/10.1071/RD09161

Hussein TS; Sutton-Mcdowall ML; Gilchrist RB; Thompson JG, 2011, 'Temporal effects of exogenous oocyte-secreted factors on bovine oocyte developmental competence during IVM', Reproduction, Fertility and Development, 23, pp. 576 - 584, http://dx.doi.org/10.1071/RD10323

Smitz JEJ; Thompson JG; Gilchrist RB, 2011, 'The promise of in vitro maturation in assisted reproduction and fertility preservation', Seminars in Reproductive Medicine, 29, pp. 24 - 37, http://dx.doi.org/10.1055/s-0030-1268701

Gilchrist RB, 2011, 'Recent insights into oocytefollicle cell interactions provide opportunities for the development of new approaches to in vitro maturation', Reproduction, Fertility and Development, 23, pp. 23 - 31, http://dx.doi.org/10.1071/RD10225

Sasseville M; Ritter LJ; Nguyen TM; Liu F; Mottershead DG; Russell DL; Gilchrist RB, 2010, 'Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells', Journal of Cell Science, 123, pp. 3166 - 3176, http://dx.doi.org/10.1242/jcs.063834

Sutton-McDowall ML; Gilchrist RB; Thompson JG, 2010, 'The pivotal role of glucose metabolism in determining oocyte developmental competence', Reproduction, 139, pp. 685 - 695, http://dx.doi.org/10.1530/REP-09-0345

van den Hout A; Gilchrist R; van der Heijden PGM, 2010, 'The randomized response log linear model as a composite link model', Statistical Modelling, 10, pp. 57 - 67, http://dx.doi.org/10.1177/1471082X0801000104

Albuz FK; Sasseville M; Lane M; Armstrong DT; Thompson JG; Gilchrist RB, 2010, 'Simulated physiological oocyte maturation (SPOM): A novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes', Human Reproduction, 25, pp. 2999 - 3011, http://dx.doi.org/10.1093/humrep/deq246

Wang Y; Nicholls PK; Stanton PG; Harrison CA; Sarraj M; Gilchrist RB; Findlay JK; Farnworth PG, 2009, 'Extra-ovarian expression and activity of growth differentiation factor 9', Journal of Endocrinology, 202, pp. 419 - 430, http://dx.doi.org/10.1677/JOE-08-0563

Sasseville M; Albuz FK; Côté N; Guillemette C; Gilchrist RB; Richard FJ, 2009, 'Characterization of novel phosphodiesterases in the bovine ovarian follicle', Biology of Reproduction, 81, pp. 415 - 425, http://dx.doi.org/10.1095/biolreprod.108.074450

Sasseville M; Nguyen TM; Ritter LJ; Russell DL; Gilchrist RB, 2009, 'Oocyte/GDF9 Regulation of Granulosa/Cumulus Cell Functions Requires EGF Receptor/MAPK3/1 Signaling.', Biology of Reproduction, 81, pp. 107 - 107, http://dx.doi.org/10.1093/biolreprod/81.s1.107

Yeo CX; Gilchrist RB; Lane M, 2009, 'Disruption of bidirectional oocyte-cumulus paracrine signaling during in vitro maturation reduces subsequent mouse oocyte developmental competence', Biology of Reproduction, 80, pp. 1072 - 1080, http://dx.doi.org/10.1095/biolreprod.108.073908

Nicholls PK; Harrison CA; Gilchrist RB; Farnworth PG; Stanton PG, 2009, 'Growth differentiation factor 9 is a germ cell regulator of sertoli cell function', Endocrinology, 150, pp. 2481 - 2490, http://dx.doi.org/10.1210/en.2008-1048

Sasseville M; Gagnon MC; Guillemette C; Sullivan R; Gilchrist RB; Richard FJ, 2009, 'Regulation of gap junctions in porcine cumulus-oocyte complexes: contributions of granulosa cell contact, gonadotropins, and lipid rafts', Molecular Endocrinology, 23, pp. 700 - 710, http://dx.doi.org/10.1210/me.2008-0320

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