By Professor Robert Bruce Gilchrist

Journal articles

Patino LC; Walton KL; Mueller TD; Johnson KE; Stocker W; Richani D; Agapiou D; Gilchrist RB; Laissue P; Harrison CA, 2017, 'BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with gdf9', Journal of Clinical Endocrinology and Metabolism, 102, pp. 1009 - 1019, http://dx.doi.org/10.1210/jc.2016-3503

Chowdhury MKH; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC; Chowdhury M, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, 7, pp. 40159, http://dx.doi.org/10.1038/srep40159

Brown HM; Dunning KR; Sutton-McDowall M; Gilchrist RB; Thompson JG; Russell DL, 2017, 'Failure to launch: Aberrant cumulus gene expression during oocyte in vitro maturation', Reproduction, 153, pp. R109 - R120, http://dx.doi.org/10.1530/REP-16-0426

Smitz JEJ; Gilchrist RB, 2016, 'Are human oocytes from stem cells next?', Nature Biotechnology, 34, pp. 1247 - 1248, http://dx.doi.org/10.1038/nbt.3742

De Vos M; Smitz J; Thompson JG; Gilchrist RB, 2016, 'The definition of IVM is clear - Variations need defining', Human Reproduction, 31, pp. 2411 - 2415, http://dx.doi.org/10.1093/humrep/dew208

Russell DL; Gilchrist RB; Brown HM; Thompson JG, 2016, 'Bidirectional communication between cumulus cells and the oocyte: Old hands and new players?', Theriogenology, 86, pp. 62 - 68, http://dx.doi.org/10.1016/j.theriogenology.2016.04.019

Wang X; Gook DA; Walters KA; Anazodo A; Ledger WL; Gilchrist RB, 2016, 'Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies', Women S Health, 12, pp. 275 - 278, http://dx.doi.org/10.2217/whe-2016-0019

Robertson DM; Gilchrist RB; Ledger WL; Baerwald A, 2016, 'Random start or emergency IVF/in vitro maturation: A new rapid approach to fertility preservation', Women S Health, 12, pp. 339 - 349, http://dx.doi.org/10.2217/whe-2015-0001

Li HJ; Sutton-Mcdowall ML; Wang X; Sugimura S; Thompson JG; Gilchrist RB, 2016, 'Extending prematuration with cAMP modulators enhances the cumulus contribution to oocyte antioxidant defence and oocyte quality via gap junctions', Human Reproduction, 31, pp. 810 - 821, http://dx.doi.org/10.1093/humrep/dew020

Gilchrist RB; Luciano AM; Richani D; Zeng HT; Wang X; De Vos M; Sugimura S; Smitz J; Richard FJ; Thompson JG, 2016, 'Oocyte maturation and quality: Role of cyclic nucleotides', Reproduction, 152, pp. R143 - R157, http://dx.doi.org/10.1530/REP-15-0606

Reader KL; Mottershead DG; Martin GA; Gilchrist RB; Heath DA; McNatty KP; Juengel JL, 2016, 'Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15', Reproduction Fertility and Development, 28, pp. 491 - 498, http://dx.doi.org/10.1071/RD14099

Mottershead DG; Sugimura S; Al-Musawi SL; Li JJ; Richani D; White MA; Martin GA; Trotta AP; Ritter LJ; Shi J; Mueller TD; Harrison CA; Gilchrist RB, 2015, 'Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a potent activator of granulosa cells and improves oocyte quality', Journal of Biological Chemistry, 290, pp. 24007 - 24020, http://dx.doi.org/10.1074/jbc.M115.671487

Gilchrist RB; Zeng HT; Wang X; Richani D; Smitz J; Thompson JG, 2015, 'Reevaluation and evolution of the simulated physiological oocyte maturation system', Theriogenology, 84, pp. 656 - 657, http://dx.doi.org/10.1016/j.theriogenology.2015.03.032

Sugimura S; Ritter LJ; Rose RD; Thompson JG; Smitz J; Mottershead DG; Gilchrist RB, 2015, 'Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes', Developmental Biology, 403, pp. 139 - 149, http://dx.doi.org/10.1016/j.ydbio.2015.05.008

Ritter LJ; Sugimura S; Gilchrist RB, 2015, 'Oocyte induction of EGF responsiveness in somatic cells is associated with the acquisition of porcine oocyte developmental competence', Endocrinology, 156, pp. 2299 - 2312, http://dx.doi.org/10.1210/en.2014-1884

Sutton-Mcdowall ML; Purdey M; Brown HM; Abell AD; Mottershead DG; Cetica PD; Dalvit GC; Goldys EM; Gilchrist RB; Gardner DK; Thompson JG, 2015, 'REDOX and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone', Molecular Reproduction and Development, 82, pp. 281 - 294, http://dx.doi.org/10.1002/mrd.22470

Spits C; Guzman L; Mertzanidou A; Jacobs K; Ortega-Hrepich C; Gilchrist RB; Thompson JG; De Vos M; Smitz J; Sermon K, 2015, 'Chromosome constitution of human embryos generated after in vitro maturation including 3-isobutyl-1-methylxanthine in the oocyte collection medium', Human Reproduction, 30, pp. 653 - 663, http://dx.doi.org/10.1093/humrep/deu329

Machado MF; Caixeta ES; Sudiman J; Gilchrist RB; Thompson JG; Lima PF; Price CA; Buratini J, 2015, 'Fibroblast growth factor 17 and bone morphogenetic protein 15 enhance cumulus expansion and improve quality of in vitro-produced embryos in cattle', Theriogenology, 84, pp. 390 - 398, http://dx.doi.org/10.1016/j.theriogenology.2015.03.031

Brown HM; Anastasi MR; Frank LA; Kind KL; Richani D; Robker RL; Russell DL; Gilchrist RB; Thompson JG, 2015, 'Hemoglobin: A gas transport molecule that is hormonally regulated in the ovarian follicle in mice and humans', Biology of Reproduction, 92, http://dx.doi.org/10.1095/biolreprod.114.124594

Li JJ; Sugimura S; Mueller TD; White MA; Martin GA; Ritter LJ; Liang XY; Gilchrist RB; Mottershead DG, 2015, 'Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes', Molecular Endocrinology, 29, pp. 40 - 52, http://dx.doi.org/10.1210/me.2014-1173

Mester B; Ritter LJ; Pitman JL; Bibby AH; Gilchrist RB; McNatty KP; Juengel JL; McIntosh CJ, 2015, 'Oocyte expression, secretion and somatic cell interaction of mouse bone morphogenetic protein 15 during the peri-ovulatory period', Reproduction Fertility and Development, 27, pp. 801 - 811, http://dx.doi.org/10.1071/RD13336

Gilchrist RB; Zeng HT; Wang X; Richani D; Smitz J; Thompson JG, 2015, 'Reevaluation and evolution of the simulated physiological oocyte maturation system', Theriogenology, http://dx.doi.org/10.1016/j.theriogenology.2015.03.032

Machado MF; Nogueira MFG; Gilchrist RB; Sutton-McDowall ML; Mottershead DG; White MA; Thompson JG, 2014, '236 EFFECT OF CYCLIC ADENOSINE MONOPHOSPHATE MODULATOR REGULATORS IN ASSOCIATION WITH BMP15 ON BOVINE EMBRYO DEVELOPMENT IN VITRO', Reproduction Fertility and Development, 27, pp. 207 - 208, http://dx.doi.org/10.1071/rdv27n1ab236

Sugimura S; Ritter LJ; Rose RD; Thompson JG; Mottershead DG; Gilchrist RB, 2014, 'BMP15 plus GDF9 and cAMP modulator promote EGF receptor signaling to increase oocyte developmental competence in porcine cumulus-oocyte complexes from small follicles', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p125

Rose RD; Sugimura S; Ritter LJ; Brown HM; Thompson JG; Gilchrist RB, 2014, 'C-type natriuretic peptide stimulates resumption of meiosis via a cGMP-dependant mechanism in porcine oocytes', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p034

Nogueira MG; Machado MF; Li H; Razza EM; Gilchrist RB; Sutton-McDowall ML; Thompson JG, 2014, 'Effect of cAMP regulators on bovine cumulus-oocyte communication and embryo development in vitro', Reproduction Abstracts, http://dx.doi.org/10.1530/repabs.1.p043

Santiquet N; Sasseville M; Laforest M; Guillemette C; Gilchrist RB; Richard FJ, 2014, 'Activation of 5' adenosine monophosphate-activated protein kinase blocks cumulus cell expansion through inhibition of protein synthesis during in vitro maturation in swine', Biology of Reproduction, 91, http://dx.doi.org/10.1095/biolreprod.113.116764

Zeng HT; Richani D; Sutton-McDowall ML; Ren Z; Smitz JEJ; Stokes Y; Gilchrist RB; Thompson JG, 2014, 'Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro- matured mouse oocytes', Biology of Reproduction, 91, http://dx.doi.org/10.1095/biolreprod.114.118471

Sudiman J; Sutton-McDowall ML; Ritter LJ; White MA; Mottershead DG; Thompson JG; Gilchrist RB, 2014, 'Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence', Plos One, 9, pp. e103563, http://dx.doi.org/10.1371/journal.pone.0103563

Sugimura S; Ritter LJ; Sutton-McDowall ML; Mottershead DG; Thompson JG; Gilchrist RB, 2014, 'Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: Effects on gap junction-mediated metabolite supply', Molecular Human Reproduction, 20, pp. 499 - 513, http://dx.doi.org/10.1093/molehr/gau013

Simpson CM; Robertson DM; Al-Musawi SL; Heath DA; McNatty KP; Ritter LJ; Mottershead DG; Gilchrist RB; Harrison CA; Stanton PG, 2014, 'Aberrant GDF9 expression and activation are associated with common human ovarian disorders', Journal of Clinical Endocrinology and Metabolism, 99, pp. E615 - E624, http://dx.doi.org/10.1210/jc.2013-3949

Richani D; Sutton-McDowall ML; Frank LA; Gilchrist RB; Thompson JG, 2014, 'Effect of epidermal growth factor-like peptides on the metabolism of in vitro-matured mouse oocytes and cumulus cells', Biology of Reproduction, 90, http://dx.doi.org/10.1095/biolreprod.113.115311

Sudiman J; Ritter LJ; Feil DK; Wang X; Chan K; Mottershead DG; Robertson DM; Thompson JG; Gilchrist RB, 2014, 'Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development', Journal of Assisted Reproduction and Genetics, 31, pp. 295 - 306, http://dx.doi.org/10.1007/s10815-013-0152-5

Frank LA; Sutton-Mcdowall ML; Brown HM; Russell DL; Gilchrist RB; Thompson JG, 2014, 'Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of Heat shock protein 90', Human Reproduction, 29, pp. 1292 - 1303, http://dx.doi.org/10.1093/humrep/deu066

Richani D; Wang X; Zeng HT; Smitz J; Thompson JG; Gilchrist RB, 2014, 'Pre-maturation with cAMP modulators in conjunction with EGF-like peptides during in vitro maturation enhances mouse oocyte developmental competence', Molecular Reproduction and Development, 81, pp. 422 - 435, http://dx.doi.org/10.1002/mrd.22307

Frank LA; Sutton-Mcdowall ML; Gilchrist RB; Thompson JG, 2014, 'The effect of peri-conception hyperglycaemia and the involvement of the hexosamine biosynthesis pathway in mediating oocyte and embryo developmental competence', Molecular Reproduction and Development, 81, pp. 391 - 408, http://dx.doi.org/10.1002/mrd.22299

Gilchrist RB; Richani D, 2013, 'Somatic guidance for the oocyte', Developmental Cell, 27, pp. 603 - 605, http://dx.doi.org/10.1016/j.devcel.2013.12.006

Thompson JG; Gilchrist RB, 2013, 'Pioneering contributions by Robert Edwards to oocyte in vitro maturation (IVM)', Molecular Human Reproduction, 19, pp. 794 - 798, http://dx.doi.org/10.1093/molehr/gat075

Frank LA; Sutton-Mcdowall ML; Russell DL; Wang X; Feil DK; Gilchrist RB; Thompson JG, 2013, 'Effect of varying glucose and glucosamine concentration in vitro on mouse oocyte maturation and developmental competence', Reproduction Fertility and Development, 25, pp. 1095 - 1104, http://dx.doi.org/10.1071/RD12275

Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2013, 'Mode of oocyte maturation affects EGF-like peptide function and oocyte competence', Molecular Human Reproduction, 19, pp. 500 - 509, http://dx.doi.org/10.1093/molehr/gat028

Caixeta ES; Sutton-McDowall ML; Gilchrist RB; Thompson JG; Price CA; Machado MF; Lima PF; Buratini J, 2013, 'Bone morphogenetic protein 15 and fibroblast growth factor 10 enhance cumulus expansion, glucose uptake, and expression of genes in the ovulatory cascade during in vitro maturation of bovine cumulus-oocyte complexes', Reproduction, 146, pp. 27 - 35, http://dx.doi.org/10.1530/REP-13-0079

Mottershead DG; Harrison CA; Mueller TD; Stanton PG; Gilchrist RB; McNatty KP, 2013, 'Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization', Proceedings of the National Academy of Sciences of the United States of America, 110, pp. E2257, http://dx.doi.org/10.1073/pnas.1303459110

Thompson JG; Mottershead DG; Gilchrist RB, 2013, 'Oocyte-Secreted Factors in Domestic Animals', , pp. 55 - 70, http://dx.doi.org/10.1002/9781118538074.ch4

Zeng HT; Ren Z; Guzman L; Wang X; Sutton-Mcdowall ML; Ritter LJ; De Vos M; Smitz J; Thompson JG; Gilchrist RB, 2013, 'Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence', Human Reproduction, 28, pp. 1536 - 1545, http://dx.doi.org/10.1093/humrep/det086

Rose RD; Gilchrist RB; Kelly JM; Thompson JG; Sutton-McDowall ML, 2013, 'Regulation of sheep oocyte maturation using cAMP modulators', Theriogenology, 79, pp. 142 - 148, http://dx.doi.org/10.1016/j.theriogenology.2012.09.020

Sutton-Mcdowall ML; Mottershead DG; Gardner DK; Gilchrist RB; Thompson JG, 2012, 'Metabolic differences in bovine cumulus-oocyte complexes matured in vitro in the presence or absence of follicle-stimulating hormone and bone morphogenetic protein 15', Biology of Reproduction, 87, http://dx.doi.org/10.1095/biolreprod.112.102061

Watson LN; Mottershead DG; Dunning KR; Robker RL; Gilchrist RB; Russell DL, 2012, 'Heparan sulfate proteoglycans regulate responses to oocyte paracrine signals in ovarian follicle morphogenesis', Endocrinology, 153, pp. 4544 - 4555, http://dx.doi.org/10.1210/en.2012-1181

Richani D; Ritter LJ; Thompson JG; Gilchrist RB, 2012, 'Consequences of In Vitro Maturation of Oocytes on Cumulus Cell EGF-Like Peptide Signaling.', Biology of Reproduction, 87, pp. 365 - 365, http://dx.doi.org/10.1093/biolreprod/87.s1.365

Sharkey DJ; Macpherson AM; Tremellen KP; Mottershead DG; Gilchrist RB; Robertson SA, 2012, 'TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells', Journal of Immunology, 189, pp. 1024 - 1035, http://dx.doi.org/10.4049/jimmunol.1200005

Voudouris V; Gilchrist R; Rigby R; Sedgwick J; Stasinopoulos D, 2012, 'Modelling skewness and kurtosis with the BCPE density in GAMLSS', Journal of Applied Statistics, 39, pp. 1279 - 1293, http://dx.doi.org/10.1080/02664763.2011.644530

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