By Professor Robert M Graham

Journal articles

Jabbour A; Hayward CS; Keogh AM; Kotlyar E; Mccrohon JA; England JF; Amor R; Liu X; Zhou MD; Graham RM; Macdonald PS, 2010, 'Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses', European Journal of Heart Failure, 13, pp. 83 - 92, http://dx.doi.org/10.1093/eurjhf/hfq152

Riek RP; Graham RM, 2010, 'The elusive pi-helix', Journal of Structural Biology, 173, pp. 153 - 160, http://dx.doi.org/10.1016/j.jsb.2010.09.001

Almaani N; Liu L; Dopping-Hepenstal PJC; Lovell PA; Lai-Cheong JE; Graham RM; Mellerio JE; McGrath JA, 2009, 'Autosomal dominant junctional epidermolysis bullosa', British Journal of Dermatology, 160, pp. 1094 - 1097, http://dx.doi.org/10.1111/j.1365-2133.2008.08977.x

Kovacic JC; Macdonald P; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, pp. e39, http://dx.doi.org/10.1016/j.ahj.2009.02.009

Jabbour A; Gao L; Kwan J; Watson A; Sun L; Liu X; Zhou M; Graham RM; Hicks M; Macdonald P, 2009, 'A Recombinant Human Neuregulin-1 Peptide Improves Preservation of the Transplanted Rat Heart After Prolonged Hypothermic Storage', Heart, Lung and Circulation, 18, pp. S168 - S168, http://dx.doi.org/10.1016/j.hlc.2009.05.382

Chih S; McCrohon J; Macdonald P; Feneley M; Graham RM, 2009, 'Exercise and Endothelial Progenitor Cells in Patients with Severe Coronary Artery Disease', Heart, Lung and Circulation, 18, pp. S112 - S113, http://dx.doi.org/10.1016/j.hlc.2009.05.255

Kovacic J; Macdonald PS; Feneley MP; Graham RM, 2009, 'Granulocyte-colony stimulating factor in refractory ischemic heart disease: Throwing stones from glass houses', American Heart Journal, 157, pp. e39, http://dx.doi.org/10.1016/j.aucc.2009.06.001

Naqvi N; Li M; Yahiro E; Graham RM; Husain A, 2009, 'Insights into the characteristics of mammalian cardiomyocyte terminal differentiation shown through the study of mice with a dysfunctional c-kit', Pediatric Cardiology, 30, pp. 651 - 658, http://dx.doi.org/10.1007/s00246-008-9366-1

Tatsukawa H; Fukaya Y; Frampton G; Martinez-Fuentes A; Suzuki K; Kuo T; Nagatsuma K; Shimokado K; Okuno M; Wu J; Iismaa SE; Matsuura T; Tsukamoto H; Zern M; Graham RM; Kojima S, 2009, 'Role of Transglutaminase 2 in Liver Injury via Cross-linking and Silencing of Transcription Factor Sp1', Gastroenterology, 136, pp. 1783 - 1795, http://dx.doi.org/10.1053/j.gastro.2009.01.007

MacDiarmid J; Amaro-Mugridge N; Madrid-Weiss J; Sedliarou I; Wetzel S; Kochar K; Brahmbhatt V; Phillips LN; Pattison S; Petti C; Stillman B; Graham RM; Brahmbhatt H, 2009, 'Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug', Nature Biotechnology, 27, pp. 643 - 651, http://dx.doi.org/10.1038/nbt.1547

Jabbour A; Hayward CS; Keogh AM; Kotlyar E; McCrohon J; England JF; Amor R; Liu X; Graham RM; Macdonald PS, 2009, 'The Safety and Efficacy of Recombinant Human Neuregulin-1 in Patients with Stable Chronic Heart Failure', Heart, Lung and Circulation, 18, pp. S192 - S192, http://dx.doi.org/10.1016/j.hlc.2009.05.436

Iismaa SE; Mearns BM; Lorand L; Graham RM, 2009, 'Transglutaminases and disease: Lessons from genetically engineered mouse models and inherited disorders', Physiological Reviews, 89, pp. 991 - 1023

Cannon L; Marciniec T; Mearns B; Graham RM; Fatkin D, 2008, 'Abstract 3435: Left Ventricular Hypertrophy is Resistant to Inhibition of Expression of the R403Q Alpha-Myosin Heavy Chain Cardiac Hypertrophy-Inducing Mutant Protein', Circulation, 118, http://dx.doi.org/10.1161/circ.118.suppl_18.s_423-c

Jabbour A; Gao L; Kwan J; Watson A; Liu XF; Zhou MD; Graham RM; Hicks M; Macdonald PS, 2008, 'A recombinant human neuregulin-1 peptide added to celsior solution improves preservation of the rat heart', EUROPEAN HEART JOURNAL, 29, pp. 110 - 110, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208702500424&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jabbour A; Gao L; Kwan J; Watson A; Liu X; Zhou M; Graham RM; Hicks M; Macdonald PS, 2008, 'IMPROVED PRESERVATION OF THE RAT HEART USING CELSIOR SOLUTION SUPPLEMENTED WITH A RECOMBINANT HUMAN NEUREGULIN-1 PEPTIDE', Transplantation, 86, pp. 55 - 56, http://dx.doi.org/10.1097/01.tp.0000332548.88129.5d

Zhao X; Zhang Y; Shen Y-T; Yan L; Vatner DE; Graham RM; Vatner SF, 2008, 'Ischemic Myocardial Protection In Transgenic Mice With Cardiac alpha(1A)-Adrenergic Receptor Overexpression', FASEB JOURNAL, 22, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208467803690&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jariwala D; Graham RM; Lewis T, 2008, 'Riga-Fede disease', British Dental Journal, 204, pp. 171, http://dx.doi.org/10.1038/bdj.2008.113

Amirahmadi F; Turnbull L; Du XJ; Graham RM; Woodcock EA, 2008, 'Heightened αIA-adrenergic receptor activity suppresses ischaemia/reperfusion-induced Ins(1,4,5)P3 generation in the mouse heart: A comparison with ischaemic preconditioning', Clinical Science, 114, pp. 157 - 164, http://dx.doi.org/10.1042/CS20070110

Li M; Naqvi N; Yahiro E; Liu KH; Powell P; Bradley W; Martin D; Dell Italia L; Graham RM; Husain A, 2008, 'c-kit is required for cardiomyocyte terminal differentiation', Circulation Research, 102, pp. 677 - 685, http://dx.doi.org/10.1161/CIRCRESAHA.107.161737

Woodcock EA; Reichelt M; Du X; Graham RM, 2008, 'Cardiac alpha(1)-adrenergic drive in pathological remodelling', Cardiovascular Research, 77, pp. 452 - 462, http://dx.doi.org/10.1093/cvr/cvm078

Kovacic JC; Moore JJ; Herbert AD; Ma DD; Boehm M; Graham RM, 2008, 'Endothelial progenitor cells, angioblasts, and angiogenesis - Old terms reconsidered from a current perspective', Trends in Cardiovascular Medicine, 18, pp. 45 - 51

Amirahmadi F; Turnbull L; Du X; Graham RM; Woodcock EA, 2008, 'Heightened alpha(1A)-adrenergic receptor activity suppresses ischaemia/reperfusion-induced Ins(1,4,5)P-3 generation in the mouse heart: a comparison with ischaemic preconditioning', Clinical Science, 114, pp. 157 - 164, http://dx.doi.org/10.1042/C20070110

Chih S; Macdonald P; Fenely M; Law M; Graham R; McCrohon J, 2008, 'Reproducibility of Adenosine Stress Cardiac Magnetic Resonance Imaging by Normalised Upslope Analysis in Patients with Severe Coronary Artery Disease', Heart, Lung and Circulation, 17, pp. S47 - S48, http://dx.doi.org/10.1016/j.hlc.2008.05.109

Kovacic JC; Macdonald P; Feneley MP; Muller DWM; Freund J; Dodds A; Milliken S; Tao H; Itescu S; Moore J; Ma D; Graham RM, 2008, 'Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD133+ cell infusion in patients with chronic refractory ischemic heart disease: the G-CSF in angina patients with IHD to stimulate neovascularization (GAIN I) trial.', Am Heart J, 156, pp. 954 - 963, http://dx.doi.org/10.1016/j.ahj.2008.04.034

Riek RP; Finch A; Begg G; Graham RM, 2008, 'Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function', Molecular Pharmacology, 73, pp. 1092 - 1104, http://dx.doi.org/10.1124/mol.107.043042

Kovacic JC; Macdonald P; Feneley MP; Muller DW; Ma D; Tao H; Freund J; Milliken S; Dodds A; Moore J; Itescu S; Graham RM, 2007, 'Abstract 2669: The Use of Granulocyte-Colony Stimulating Factor in Angina Patients to Stimulate Neovascularization: the GAIN I study', Circulation, 116, http://dx.doi.org/10.1161/circ.116.suppl_16.ii_591-d

Jariwala D; Graham RM; Lowry JC, 2007, 'Altered sensation [1]', British Dental Journal, 203, pp. 227, http://dx.doi.org/10.1038/bdj.2007.795

Graham RM; Cousin GCS, 2007, 'Access to the chin [10]', British Dental Journal, 202, pp. 645, http://dx.doi.org/10.1038/bdj.2007.490

Kovacic JC; Muller DW; Graham RM, 2007, 'Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease', Journal of Molecular and Cellular Cardiology, 42, pp. 19 - 33

MacDiarmid J; Mugridge N; Weiss J; Phillips LN; Burn AL; Paulin R; Haasdyk J; Dickson K; Brahmbhatt V; Pattison S; James AC; Al Bakri G; Straw R; Stillman B; Graham RM; Brahmbhatt H, 2007, 'Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics', Cancer Cell, 11, pp. 431 - 445

Kovacic JC; Ma DD; Tao H; Herbert AD; Moore JJ; Graham RM, 2007, 'Phenotypic characterization of CD133+cells suggests a potent hemangioblast population', Circulation Research, 101, pp. E55 - E56

Kovacic JC; Macdonald PS; Freund J; Rasko J; Allan RM; Fernandes VB; Ma DD; Moore JJ; Graham RM, 2007, 'Profound thrombocytopenia related to G-CSF', American Journal of Hematology, 82, pp. 229 - 230

Jabbour A; Hayward C; Keogh A; Kotlyar E; Liu X; Zhou MD; Li XY; McCrohon J; Graham RM; Macdonald P, 2007, 'Recombinant Human Neuregulin-1 (rhNRG-1) Improves Cardiac Output in Patients with Stable Chronic Heart Failure', Heart, Lung and Circulation, 16, pp. S13 - S13, http://dx.doi.org/10.1016/j.hlc.2007.06.034

Ju Y; Chu YH; Chaulet H; Lai D; Gervasio OL; Graham RM; Cannells M; Allen DG, 2007, 'Store-Operated Ca2+ Influx and Expression of TRPC Genes in Mouse Sinoatrial Node', Circulation Research, 100 (11), pp. 1605 - 1614

Strnad P; Harada M; Siegel M; Terkeltaub R; Graham RM; Khosla C; Omary M, 2007, 'Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement', Gastroenterology, 132, pp. 1515 - 1526

Thomas AC; Cullup T; Norgett EE; Hill T; Barton S; Dale BA; Sprecher E; Sheridan E; Taylor AE; Wilroy RS; DeLozier C; Burrows N; Goodyear H; Fleckman P; Stephens KG; Mehta L; Watson RM; Graham R; Wolf R; Slavotinek A; Martin M; Bourn D; Mein CA; O'Toole EA; Kelsell DP, 2006, 'ABCA12 is the major harlequin ichthyosis gene', Journal of Investigative Dermatology, 126, pp. 2408 - 2413, http://dx.doi.org/10.1038/sj.jid.5700455

Begg GE; Holman SR; Stokes PH; Matthews JM; Graham RM; Iismaa SE, 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', JOURNAL OF BIOLOGICAL CHEMISTRY, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200

Finch AM; Graham RM, 2006, 'The α1D-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4, http://dx.doi.org/10.1124/mol.105.020230

Du XR; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Wang K; Finch A; Dart A; Graham RM, 2006, 'Cardiac overexpression of the alpha(1A)-adrenergic receptor limits post-infarct ventricular remodeling and dysfunction, and improves survival', Journal of Molecular and Cellular Cardiology, 41, pp. 735 - 735

Iismaa S; Begg G; Graham RM, 2006, 'Cross-linking transglutaminases with G protein-coupled receptor signaling.', Science S Stke, 353, pp. pe34, http://dx.doi.org/10.1126/stke.3532006pe34

Begg G; Carrington L; Stokes P; Matthews JM; Wouters MA; Husain A; Lorand L; Iismaa SE; Graham RM, 2006, 'Mechanism of allosteric regulation of transglutaminase 2 by GTP', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 19683 - 19688

Begg G; Holman S; Stokes P; Matthews J; Graham RM; Iismaa SE; Holman , 2006, 'Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity', The Journal of Biological Chemistry, 281, pp. 12603 - 12609, http://dx.doi.org/10.1074/jbc.M600146200

Liu X; Gu X; Li Z; Li X; Li H; Chang J; Chen PP; Jin J; Xi B; Chen D; Lai D; Graham RM; Zhou M, 2006, 'Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy', Journal of the American College of Cardiology, 48, pp. 1438 - 1447

Chaulet H; Guo J; Owens WA; Michalicek J; Kesteven SH; Guan Z; Prall OW; Mearns BM; Feneley MP; Steinberg S; Graham RM, 2006, 'Sustained augmentation of cardiac alpha(1A)-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes', Journal of Molecular and Cellular Cardiology, 40, pp. 540 - 552

Finch A; Graham RM, 2006, 'The alpha(1D)-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4

Du X; Gao X; Kiriazis H; Moore X; Ming Z; Su Y; Finch A; Hannan R; Dart A; Graham RM, 2006, 'Transgenic alpha(1A)-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival', Cardiovascular Research, 71, pp. 735 - 743

D.F. D; Kovacic JC; Dodds A; Tao H; McDonald P; Feneley MP; Muller DW; Fruend J; Milliken S; Moore J; Itescu S; Graham RM, 2005, 'Granulocyte-Colony Stimulating Factor Decreases Angina and Improves Exercise Capacity in Patients with Chronic Refractory ‘No Option' Ischemic Heart Disease.', Blood, 106, pp. 4215, http://dx.doi.org/10.1182/blood.v106.11.4215.4215

James M; Hoff T; Davis J; Graham R, 2005, 'Grant watch report: Leveraging the power of the media to combat HIV/AIDS: The Kaiser Family Foundation's partnerships with media and others to help educate the public about HIV/AIDS, here and abroad', Health Affairs, 24, pp. 854 - 857, http://dx.doi.org/10.1377/hlthaff.24.3.854

Kovacic JC; Graham RM, 2005, 'Are improvements in cardiac function due to stem cell uptake and engraftment?', American Journal of Cardiology, 95, pp. 159, http://dx.doi.org/10.1016/j.amjcard.2004.07.138

Byrne A; Graham G; Hallinan R; Murnion B; Hulse GK; Arnold-Reed DE; Wodak A; Graham R; Hulse GK, 2005, 'Naltrexone implants as treatment for heroin dependence: Part I (multiple letters)', Addiction Biology, 10, pp. 201, http://dx.doi.org/10.1080/13556210500155789

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