By Professor Sally Dunwoodie

Journal articles

Dunwoodie SL; Sparrow DB; Chapman G, 2011, 'The mouse notches up another success: understanding the causes of human vertebral malformation', Mammalian Genome, 22, pp. 362 - 376, http://dx.doi.org/10.1007/s00335-011-9335-5

Harvey RP; Dunwoodie SL; Fatkin D; Qian L; Wythe JD; Liu J; Liu J; Vogler G; Mohapatra B; Otway R; Huang Y; King IN; Maillet M; Zheng Y; Crawley T; Taghli-Lamallem O; Semsarian C; Winlaw D, 2011, 'Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species', Journal of Cell Biology, 193, pp. 1181 - 1196, http://dx.doi.org/10.1083/jcb.201006114

Combes A; Spiller C; Harley V; Sinclair AH; Dunwoodie SL; Wilhelm D; Koopman P, 2010, 'Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation', International Journal of Developmental Biology, 54, pp. 683 - 689, http://dx.doi.org/10.1387/ijdb.092920ac

Dunwoodie SL, 2009, 'Mutation of the fucose-specific beta 1,3 N-acetylglucosaminyltransferase UNG results in abnormal formation of the spine (Reprinted)', BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1792, pp. 862 - 873, http://dx.doi.org/10.1016/j.bbadis.2008.11.003

Chen Y; Carlson E; Chen Z; Hamik A; Jain MK; Dunwoodie SL; Yang Y, 2009, 'Conditional deletion of Cited2 results in defective corneal epithelial morphogenesis and maintenance', Developmental Biology, 334, pp. 243 - 252, http://dx.doi.org/10.1016/j.ydbio.2009.07.028

Sewell WA; Sparrow DB; Smith A; Gonzalez D; Rappaport E; Dunwoodie SL; Kusumi K, 2009, 'Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis', Developmental Biology, 329, pp. 400 - 409, http://dx.doi.org/10.1016/j.ydbio.2009.02.023

Dunwoodie SL, 2009, 'Mutation of the fucose-specific beta 1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine', Biochimica et Biophysica ACTA - Molecular Basis of Disease, 1792, pp. 100 - 111, http://dx.doi.org/10.1016/j.bbadis.2008.11.003

Sparrow DB; Boyle S; Sams R; Mazuruk B; Zhang L; Moeckel G; Dunwoodie SL; de Caestecker MP, 2009, 'Placental insufficiency associated with loss of Cited1 causes renal medullary dysplasia', Journal of the American Society of Nephrology, 20, pp. 777 - 786, http://dx.doi.org/10.1681/ASN.2008050547

Giampietro P; Dunwoodie SL; Kusumi K; Pourquie O; Tassy O; Offiah AC; Cornier A; Alman B; Blank R; Raggio C; Glurich I; Turnpenny PD, 2009, 'Progress in the understanding of the genetic etiology of vertebral segmentation disorders in humans', Annals of the New York Academy of Sciences, 1151, pp. 38 - 67, http://dx.doi.org/10.1111/j.1749-6632.2008.03452.x

Dunwoodie SL, 2009, 'The Role of Hypoxia in Development of the Mammalian Embryo', Developmental Cell, 17, pp. 755 - 773, http://dx.doi.org/10.1016/j.devcel.2009.11.008

Dunwoodie SL, 2009, 'The role of Notch in patterning the human vertebral column', Current Opinion in Genetics and Development, 19, pp. 329 - 337, http://dx.doi.org/10.1016/j.gde.2009.06.005

Giampietro PF; Dunwoodie SL; Kusumi K; Pourquié O; Tassy O; Offiah AC; Cornier AS; Alman BA; Blank RD; Raggio CL; Glurich I; Turnpenny PD, 2008, 'Molecular diagnosis of vertebral segmentation disorders in humans', Expert Opinion on Medical Diagnostics, 2, pp. 1107 - 1121, http://dx.doi.org/10.1517/17530059.2.10.1107

Loomes KM; Stevens SA; O'Brien ML; Gonzalez DM; Ryan MJ; Segalov M; Dormans NJ; Mimoto MS; Gibson JD; Sewell W; Schaffer AA; Nah HD; Rappaport EF; Pratt SC; Dunwoodie SL; Kusumi K, 2008, 'Dll3 and Notchl genetic interactions model axial segmental and craniofacial malformations of human birth defects (Developmental Dynamics 236, (2943-2951))', Developmental Dynamics, 237, pp. 1754, http://dx.doi.org/10.1002/dvdy.21580

Furtado MB; Solloway MJ; Jones V; Costa M; Biben C; Wolstein O; Preis JI; Sparrow DB; Saga Y; Dunwoodie SL; Robertson E; Tam P; Harvey RP, 2008, 'BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4', Genes and Development, 22, pp. 3037 - 3049

Xu B; Qu X; Gu S; Doughman Y; Watanabe M; Dunwoodie SL; Yang Y, 2008, 'Cited2 is required for fetal lung maturation', Developmental Biology, 317, pp. 95 - 105, http://dx.doi.org/10.1016/j.ydbio.2008.02.019

Chen Y; Doughman Y; Gu S; Jarrell A; Aota S; Cvekl A; Watanabe M; Dunwoodie SL; Johnson R; van Heyningen V; Kleinjan D; Beebe D; Yang Y, 2008, 'Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis', Development (Cambridge), 135, pp. 2939 - 2948

Sparrow DB; Guillen-Navarro E; Fatkin D; Dunwoodie SL, 2008, 'Mutation of HAIRY-AND-ENHANCER-OF-SPLIT-7 in humans causes spondylocostal dysostosis', Human Molecular Genetics, 17, pp. 3761 - 3766

Blewitt M; Gendrel A; Pang Z; Sparrow DB; Whitelaw N; Apedaile A; Hilton DJ; Dunwoodie SL; Brockdorff N; Kay G; Whitelaw E, 2008, 'SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation', Nature Genetics, 40, pp. 663 - 669, http://dx.doi.org/10.1038/ng.142

Coman D; Bacic S; Boys A; Sparrow DB; Dunwoodie SL; Savarirayan R; Amor D, 2008, 'Spondylocostal dysostosis in a pregnancy complicated by confined placental mosaicism for tetrasomy 9p', American Journal of Medical Genetics Part A, 146A, pp. 1972 - 1976

Geffers I; Serth K; Chapman G; Jaekel R; Schuster-Gossler K; Cordes R; Sparrow DB; Kremmer E; Dunwoodie SL; Klein T; Gossler A, 2007, 'Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo', The Journal of Experimental Medicine, 204, pp. i20 - i20, http://dx.doi.org/10.1084/jem2048oia20

Turnpenny PD; Alman B; Cornier A; Giampietro P; Offiah A; Tassy O; Pourquie O; Kusumi K; Dunwoodie SL, 2007, 'Abnormal vertebral segmentation and the notch signaling pathway in man', Developmental Dynamics, 236, pp. 1456 - 1474

Qu XJ; Lam E; Doughman Y; Chen Y; Chou Y; Lam MK; Turakhia M; Dunwoodie SL; Watanabe M; Xu B; Duncan S; Yang YW, 2007, 'Cited2, a coactivator of HNF4a, is essential for liver development', European Molecular Biology Organization, 26, pp. 4445 - 4456

Dunwoodie SL, 2007, 'Combinatorial signaling in the heart orchestrates cardiac induction, lineage specification and chamber formation', Seminars in Cell and Developmental Biology, 18, pp. 54 - 66

Loomes K; Stevens S; O Brien ML; Gonzalez D; Ryan MJ; Segalov M; Dormans N; Mimoto M; Gibson G; Schaffer A; Nah H; Rappaport E; Pratt S; Dunwoodie SL; Kusumi K, 2007, 'D113 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects', Developmental Dynamics, 236, pp. 2943 - 2951

Sparrow DB; Chapman G; Turnpenny PD; Dunwoodie SL, 2007, 'Disruption of the somitic molecular clock causes abnormal vertebral segmentation', Birth Defects Research Part C: Embryo Today: Reviews, 81 (2), pp. 93 - 110

Geffers I; Serth K; Chapman G; Jaekel R; Schuster-Gossler K; Cordes R; Sparrow DB; Kremmer E; Dunwoodie SL; Klein T; Gossler A, 2007, 'Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo', Journal of Cell Biology, 178, pp. 465 - 476

Loomes K; Stevens S; O Brien M; Gonzalez D; Ryan MJ; Segalov M; Dormans N; Mimoto M; Gibson J; Schaffer A; Nah H; Rappaport E; Pratt S; Dunwoodie SL; Kusumi K, 2007, 'Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects', Developmental Dynamics, 236, pp. 2943 - 2951

Dunwoodie SL; Sparrow DB; Chapman G, 2007, 'The Yin and Yang of Notch signalling; trans-activation and cis-inhibition fine-tune Notch signalling', Developmental Biology, 306, pp. 335 - 335

Elliott DA; Solloway MJ; Wise N; Biben C; Costa M; Furtado MB; Lange M; Dunwoodie SL; Harvey RP, 2006, 'A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery', Development (Cambridge), 133, pp. 1311 - 1322

Preis JI; Wise N; Solloway MJ; Harvey RP; Sparrow DB; Dunwoodie SL, 2006, 'Generation of conditional Cited2 null alleles', Genesis, 44, pp. 579 - 583

Withington SL; Scott AN; Saunders DN; Floro KL; Preis JI; Michalicek J; Maclean K; Sparrow DB; Barbera JP; Dunwoodie SL, 2006, 'Loss of Cited2 affects trophoblast and vascularization of the mouse placenta', Developmental Biology, 294, pp. 67 - 82

Sparrow DB; Chapman G; Wouters MA; Whittock N; Ellard S; Fatkin D; Turnpenny PD; Kusumi K; Sillence D; Dunwoodie SL, 2006, 'Mutation of the LUNATIC FRINGE Gene in Humans Causes Spondylocostal Dysostosis with a Severe Vertebral Phenotype', American Journal of Human Genetics, 78, pp. 25 - 34

Shi G; Boyle S; Sparrow DB; Dunwoodie SL; Shioda T; de Caestecker M, 2006, 'The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner', The Journal of Biological Chemistry, 281, pp. 27426 - 27435

Maclean K; Lopes-Floro K; Sparrow D; Winlaw D; Dunwoodie SL, 2005, 'Assessing the role of Cited2 in human congenital heart disease (CHD)', MECHANISMS OF DEVELOPMENT, 122, pp. S54 - S54, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100198&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Floro LK; Preis J; Sparrow DB; Dunwoodie SD, 2005, 'Cited2 is essential for the establishment of the left-right axis', MECHANISMS OF DEVELOPMENT, 122, pp. S104 - S104, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100390&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dunwoodie SL; Floro LK; Mohun T, 2005, 'Cited2 is required for normal cardiovascular development', MECHANISMS OF DEVELOPMENT, 122, pp. S93 - S93, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100348&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sparrow DB; Chapman G; Whittock N; Sillence D; Ellard S; Turnpenny PD; Dunwoodie SL, 2005, 'Mutation of the LUNATIC FRINGE gene causes spondylocostal dysostosis in humans', MECHANISMS OF DEVELOPMENT, 122, pp. S152 - S153, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100576&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Stennard FA; Costa MW; Lai D; Biben C; Solloway MJ; Preis J; Dunwoodie S; Prall OWJ; Harvey RP, 2005, 'T-box transcription factor Tbx20 is an important transcriptional repressor in vivo and is essential for murine embryonic heart development', MECHANISMS OF DEVELOPMENT, 122, pp. S58 - S59, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100214&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Woolford M; Prall O; Tam PPL; Harvey RP; Dunwoodie SL, 2005, 'The expression profile of the germ layers and primitive streak in 7.5 dpc mouse embryos', MECHANISMS OF DEVELOPMENT, 122, pp. S147 - S147, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100555&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Preis J; Sparrow D; Wise N; Lopes-Floro K; Harvey RP; Dunwoodie SL, 2005, 'Understanding the various roles that Cited2 plays during mouse development', MECHANISMS OF DEVELOPMENT, 122, pp. S67 - S68, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000207524100249&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Plisov S; Tsang M; Shi G; Boyle S; Yoshino K; Dunwoodie SL; Dawid I; Shioda T; Perantoni A; de Caestecker MP, 2005, 'Cited1 Is a bifunctional transcriptional cofactor that regulates early nephronic patterning', Journal of the American Society of Nephrology, 16, pp. 1632 - 1644

Weninger WJ; Floro KL; Bennett MB; Withington SL; Preis JI; Barbera JP; Mohun T; Dunwoodie SL, 2005, 'Cited2 is required both for heart mophogenesis and establishment of the left-right axis in mouse development', Development (Cambridge), 132, pp. 1337 - 1348

Dunwoodie SL; Floro K; Weninger W; Preis J; Mohun T, 2005, 'Cited2 is required for heart morphogenesis and establishment of the left-right axis in mouse', Developmental Biology, 283, pp. 677 - 677

Wouters MA; Rigoutsos I; Chu CK; Feng L; Sparrow DB; Dunwoodie SL, 2005, 'Evolution of distinct EGF domains with specific functions', Protein Science, 14, pp. 1091 - 1103

Stennard FA; Costa M; Lai D; Biden C; Furtado MB; Solloway MJ; McCulley D; Leimena C; Preis JI; Dunwoodie SL; Elliott D; Prall OW; Black B; Fatkin D; Harvey RJ, 2005, 'Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaption', Development (Cambridge), 132, pp. 2451 - 2462

Saunders DN; Hird SL; Withington SL; Dunwoodie SL; Henderson MJ; Biben C; Sutherland RL; Ormandy CJ; Watts CKW, 2004, 'Erratum: Edd, the murine ortholog of the hyperplastic discs (hyd) gene, is essential for yolk sac vascularization and chorioallantoic fusion (Molecular and Cellular Biology (2004) 24: 16 (7225-7234))', Molecular and Cellular Biology, 24, pp. 9262, http://dx.doi.org/10.1128/MCB.24.20.9262.2004

Kusumi K; Mimoto MS; Covello KL; Beddington RSP; Krumlauf R; Dunwoodie SL, 2004, 'Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes', Genesis (United States), 39, pp. 115 - 121, http://dx.doi.org/10.1002/gene.20034

Dunwoodie SL; Withington SL; Sparrow DB; Scott AN; Preis JI; Michalicek J, 2004, '016.Role of cited genes in placental morphogenesis: studies in null mutant mice', Reproduction, Fertility and Development, 16, pp. 16 - 16, http://dx.doi.org/10.1071/srb04abs016

Maclean K; Dunwoodie SL, 2004, 'Breaking symmetry: a clinical overview of left-right patterning', Clinical Geriatrics, 65, pp. 441 - 457

Rodriguez TA; Sparrow DB; Scott AN; Withington SL; Preis J; Michalicek J; Clements M; Tsang T; Shioda T; Beddington RS; Dunwoodie SL, 2004, 'Cited1 is required in trophoblasts for placental development and for embryo growth and survival', Molecular and Cellular Biology, 24, pp. 228 - 244, http://dx.doi.org/10.1128/MCB.24.1.228-244.2004

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