By Scientia Professor Gary David Housley

Journal articles

Pinyon JL; von Jonquieres G; Crawford EN; Abed AA; Power JM; Klugmann M; Browne CJ; Housley DM; Wise AK; Fallon JB; Shepherd RK; Lin JY; McMahon C; McAlpine D; Birman CS; Lai W; Enke YL; Carter PM; Patrick JF; Gay RD; Marie C; Scherman D; Lovell NH; Housley GD, 2024, 'Gene Electrotransfer via Conductivity-Clamped Electric Field Focusing Pivots Sensori-Motor DNA Therapeutics: “A Spoonful of Sugar Helps the Medicine Go Down”', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202401392

Parmar J; von Jonquieres G; Gorlamandala N; Chung B; Craig AJ; Pinyon JL; Birnbaumer L; Klugmann M; Moorhouse AJ; Power JM; Housley GD, 2024, 'TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca²⁺ Dysregulation Leading to Secondary Brain Injury in the Mouse Model', Translational Stroke Research, 15, pp. 844 - 858, http://dx.doi.org/10.1007/s12975-023-01173-1

Achanta LB; Thomas DS; Housley GD; Rae CD, 2024, 'AMP-activated protein kinase activators have compound and concentration-specific effects on brain metabolism', Journal of Neurochemistry, 168, pp. 677 - 692, http://dx.doi.org/10.1111/jnc.15815

Vlajkovic SM; Housley GD; Thorne PR, 2024, 'Auckland hearing science discovery and translation in purinergic signaling and inner ear therapeutics', Journal of the Royal Society of New Zealand, http://dx.doi.org/10.1080/03036758.2024.2359945

Pinyon JL; von Jonquieres G; Mow SL; Abed AA; Lai KY; Manoharan M; Crawford EN; Xue SH; Smith-Moore S; Caproni LJ; Milsom S; Klugmann M; Lovell NH; Housley GD, 2024, 'Vector-Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity-Clamped Gene Electrotransfer', Advanced Science, http://dx.doi.org/10.1002/advs.202406545

, 2024, 'Gene Electrotransfer via Conductivity‐Clamped Electric Field Focusing Pivots Sensori‐Motor DNA Therapeutics: “A Spoonful of Sugar Helps the Medicine Go Down” (Adv. Sci. 30/2024)', Advanced Science, 11

Housley GD; Nadar Ponniah PT; von Wegner F; Cederholm JM, 2023, 'Mouse models reveal P2X2 receptor-mediated hearing adaptation is an indicator of noise-induced hearing loss vulnerability', The Journal of the Acoustical Society of America, 154, pp. A298 - A298, http://dx.doi.org/10.1121/10.0023588

Kalotay E; Klugmann M; Housley GD; Fröhlich D, 2023, 'Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models', Frontiers in Neuroscience, 17, http://dx.doi.org/10.3389/fnins.2023.1182845

Kalotay E; Klugmann M; Housley GD; Fröhlich D, 2023, 'Recessive aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models', Frontiers in Neuroscience, 17, http://dx.doi.org/10.3389/fnins.2023.1182874

Klugmann M; Suchowerska AK; Housley GD; Fröhlich D, 2023, 'Histological and biochemical methods to assess aminoacyl-tRNA synthetase expression in human post-mortem brain tissue', Rare Disease and Orphan Drugs Journal, 2, pp. 8 - 8, http://dx.doi.org/10.20517/rdodj.2023.05

Fröhlich D; Kalotay E; von Jonquieres G; Bongers A; Lee B; Suchowerska AK; Housley GD; Klugmann M, 2022, 'Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice', Frontiers in Molecular Neuroscience, 15, http://dx.doi.org/10.3389/fnmol.2022.1061257

Cederholm JME; Parley KE; Perera CJ; von Jonquieres G; Pinyon JL; Julien JP; Ryugo DK; Ryan AF; Housley GD, 2022, 'Noise-induced hearing loss vulnerability in type III intermediate filament peripherin gene knockout mice', Frontiers in Neurology, 13, http://dx.doi.org/10.3389/fneur.2022.962227

Housley DM; Irani D; Housley GD; Ten Cate WJF, 2022, 'Audiological and Surgical Correlates of Myringoplasty Associated with Ethnography in the Bay of Plenty, New Zealand', Audiology and Neurotology, 27, pp. 406 - 417, http://dx.doi.org/10.1159/000524312

Klugmann M; Kalotay E; Delerue F; Ittner LM; Bongers A; Yu J; Morris MJ; Housley GD; Fröhlich D, 2022, 'Correction to: Developmental delay and late onset HBSL pathology in hypomorphic Dars1 ^M256L mice (Neurochemical Research, (2022), 47, 7, (1972-1984), 10.1007/s11064-022-03582-4)', Neurochemical Research, 47, pp. 1985 - 1990, http://dx.doi.org/10.1007/s11064-022-03602-3

Klugmann M; Kalotay E; Delerue F; Ittner LM; Bongers A; Yu J; Morris MJ; Housley GD; Fröhlich D, 2022, 'Developmental delay and late onset HBSL pathology in hypomorphic Dars1 ^M256L mice', Neurochemical Research, 47, pp. 1972 - 1984, http://dx.doi.org/10.1007/s11064-022-03582-4

von Jonquieres G; Rae CD; Housley GD, 2021, 'Emerging Concepts in Vector Development for Glial Gene Therapy: Implications for Leukodystrophies', Frontiers in Cellular Neuroscience, 15, pp. 661857, http://dx.doi.org/10.3389/fncel.2021.661857

Muthiah A; Housley GD; Klugmann M; Fröhlich D, 2021, 'The Leukodystrophies HBSL and LBSL—Correlates and Distinctions', Frontiers in Cellular Neuroscience, 14, http://dx.doi.org/10.3389/fncel.2020.626610

Fröhlich D; Mendes MI; Kueh AJ; Bongers A; Herold MJ; Salomons GS; Housley GD; Klugmann M, 2021, 'A Hypomorphic Dars1^D367Y Model Recapitulates Key Aspects of the Leukodystrophy HBSL', Frontiers in Cellular Neuroscience, 14, http://dx.doi.org/10.3389/fncel.2020.625879

Housley GD; von Jonquieres G; Pinyon JL; Matheson JAT; Pearson LJ; Salthouse TP; Cederholm JM, 2020, 'Cochlear homeostasis: a molecular physiological perspective on maintenance of sound transduction and auditory neurotransmission with noise and ageing', Current Opinion in Physiology, 18, pp. 106 - 115, http://dx.doi.org/10.1016/j.cophys.2020.09.012

Das A; Fröhlich D; Achanta LB; Rowlands BD; Housley GD; Klugmann M; Rae CD, 2020, 'Correction to: L-Aspartate, L-Ornithine and L-Ornithine-L-Aspartate (LOLA) and Their Impact on Brain Energy Metabolism (Neurochemical Research, (2020), 45, 6, (1438-1450), 10.1007/s11064-020-03044-9)', Neurochemical Research, 45, pp. 2527, http://dx.doi.org/10.1007/s11064-020-03087-y

Das A; Fröhlich D; Achanta LB; Rowlands BD; Housley GD; Klugmann M; Rae CD; Froehlich D, 2020, 'L-Aspartate, L-Ornithine and L-Ornithine-L-Aspartate (LOLA) and Their Impact on Brain Energy Metabolism', Neurochemical Research, 45, pp. 1438 - 1450, http://dx.doi.org/10.1007/s11064-020-03044-9

Przybyla M; Van Eersel J; Van Hummel A; Van Der Hoven J; Sabale M; Harasta A; Müller J; Gajwani M; Prikas E; Mueller T; Stevens CH; Power J; Housley GD; Karl T; Kassiou M; Ke YD; Ittner A; Ittner LM, 2020, 'Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature', Brain, 143, pp. 1889 - 1904, http://dx.doi.org/10.1093/brain/awaa133

Housley DM; Pinyon JL; Von Jonquieres G; Perera CJ; Smout M; Liddell MJ; Jennings EA; Wilson D; Housley GD, 2020, 'Australian scorpion Hormurus waigiensis venom fractions show broad bioactivity through modulation of bio-impedance and cytosolic calcium', Biomolecules, 10, http://dx.doi.org/10.3390/biom10040617

Pinyon JL; von Jonquieres G; Crawford EN; Duxbury M; Al Abed A; Lovell NH; Klugmann M; Wise AK; Fallon JB; Shepherd RK; Birman CS; Lai W; McAlpine D; McMahon C; Carter PM; Enke YL; Patrick JF; Schilder AGM; Marie C; Scherman D; Housley GD, 2019, 'Neurotrophin gene augmentation by electrotransfer to improve cochlear implant hearing outcomes', Hearing Research, 380, pp. 137 - 149, http://dx.doi.org/10.1016/j.heares.2019.06.002

Cederholm JME; Ryan AF; Housley GD, 2019, 'Onset kinetics of noise-induced purinergic adaptation of the ‘cochlear amplifier’', Purinergic Signalling, 15, pp. 343 - 355, http://dx.doi.org/10.1007/s11302-019-09648-3

Al Abed A; Pinyon JL; Foster E; Crous F; Cowin GJ; Housley GD; Lovell NH, 2019, 'Computational Simulation Expands Understanding of Electrotransfer-Based Gene Augmentation for Enhancement of Neural Interfaces', Frontiers in Neuroscience, 13, pp. 691, http://dx.doi.org/10.3389/fnins.2019.00691

Cederholm JME; Kim Y; von Jonquieres G; Housley GD, 2019, 'Human Brain Region-Specific Alternative Splicing of TRPC3, the Type 3 Canonical Transient Receptor Potential Non-Selective Cation Channel', Cerebellum, 18, pp. 536 - 543, http://dx.doi.org/10.1007/s12311-019-01026-4

Lin SCY; Thorne PR; Housley GD; Vlajkovic SM, 2019, 'Purinergic signaling and aminoglycoside ototoxicity: The opposing roles of P1 (adenosine) and P2 (ATP) receptors on cochlear hair cell survival', Frontiers in Cellular Neuroscience, 13, http://dx.doi.org/10.3389/fncel.2019.00207

Pinyon JL; Klugmann M; Lovell NH; Housley GD, 2019, 'Dual-Plasmid Bionic Array-Directed Gene Electrotransfer in HEK293 Cells and Cochlear Mesenchymal Cells Probes Transgene Expression and Cell Fate', Human Gene Therapy, 30, pp. 211 - 224, http://dx.doi.org/10.1089/hum.2018.062

Gorlamandala N; Parmar J; Craig AJ; Power JM; Moorhouse AJ; Krishnan AV; Housley GD, 2018, 'Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model', Translational Stroke Research, 9, pp. 643 - 653, http://dx.doi.org/10.1007/s12975-018-0615-1

Lin SCY; Thorne PR; Housley GD; Vlajkovic SM, 2018, 'Resistance to neomycin ototoxicity in the extreme basal (hook) region of the mouse cochlea', Histochemistry and Cell Biology, 150, pp. 281 - 289, http://dx.doi.org/10.1007/s00418-018-1683-8

Fröhlich D; Suchowerska AK; Voss C; He R; Wolvetang E; Von Jonquieres G; Simons C; Fath T; Housley GD; Klugmann M; Froehlich D, 2018, 'Expression pattern of the aspartyl-tRNA synthetase DARS in the human brain', Frontiers in Molecular Neuroscience, 11, pp. 81, http://dx.doi.org/10.3389/fnmol.2018.00081

Palmer JC; Lord MS; Pinyon JL; Wise AK; Lovell NH; Carter PM; Enke YL; Housley GD; Green RA; Palmer J, 2018, 'Comparing perilymph proteomes across species', Laryngoscope, 128, pp. E47 - E52, http://dx.doi.org/10.1002/lary.26885

von Jonquieres G; Spencer ZHT; Rowlands BD; Klugmann CB; Bongers A; Harasta AE; Parley KE; Cederholm J; Teahan O; Pickford R; Delerue F; Ittner LM; Fröhlich D; McLean CA; Don AS; Schneider M; Housley GD; Rae CD; Klugmann M; Froehlich D, 2018, 'Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy', Acta Neuropathologica, 135, pp. 95 - 113, http://dx.doi.org/10.1007/s00401-017-1784-9

Yamasaki A; Hoehle LP; Phillips KM; Feng AL; Campbell AP; Caradonna DS; Gray ST; Sedaghat AR, 2018, 'Association between systemic antibiotic and corticosteroid use for chronic rhinosinusitis and quality of life.', Laryngoscope, 128, pp. 37 - 42, http://dx.doi.org/10.1002/lary.26778

Goulton CS; Watanabe M; Cheung DL; Wang KW; Oba T; Khoshaba A; Lai D; Inada H; Eto K; Nakamura K; Power JM; Lewis TM; Housley GD; Wake H; Nabekura J; Moorhouse AJ, 2018, 'Conditional Upregulation of KCC2 selectively enhances neuronal inhibition during seizures', , http://dx.doi.org/10.1101/253831

Housley DM; Housley GD; Liddell MJ; Jennings EA, 2017, 'Scorpion toxin peptide action at the ion channel subunit level', Neuropharmacology, 127, pp. 46 - 78, http://dx.doi.org/10.1016/j.neuropharm.2016.10.004

Bi M; Gladbach A; Van Eersel J; Ittner A; Przybyla M; Van Hummel A; Chua SW; Hoven JVD; Lee WS; Müller J; Parmar J; Jonquieres GV; Stefen H; Guccione E; Fath T; Housley GD; Klugmann M; Ke YD; Ittner LM, 2017, 'Tau exacerbates excitotoxic brain damage in an animal model of stroke', Nature Communications, 8, http://dx.doi.org/10.1038/s41467-017-00618-0

Kurabi A; Keithley EM; Housley GD; Ryan AF; Wong ACY, 2017, 'Cellular mechanisms of noise-induced hearing loss', Hearing Research, 349, pp. 129 - 137, http://dx.doi.org/10.1016/j.heares.2016.11.013

Achanta LB; Rowlands BD; Thomas DS; Housley GD; Rae CD, 2017, 'β-Hydroxybutyrate Boosts Mitochondrial and Neuronal Metabolism but is not Preferred Over Glucose Under Activated Conditions', Neurochemical Research, 42, pp. 1710 - 1723, http://dx.doi.org/10.1007/s11064-017-2228-6

Vlajkovic SM; Ambepitiya K; Barclay M; Boison D; Housley GD; Thorne PR, 2017, 'Adenosine receptors regulate susceptibility to noise-induced neural injury in the mouse cochlea and hearing loss', Hearing Research, 345, pp. 43 - 51, http://dx.doi.org/10.1016/j.heares.2016.12.015

Fröhlich D; Suchowerska AK; Spencer ZHT; von Jonquieres G; Klugmann CB; Bongers A; Delerue F; Stefen H; Ittner LM; Fath T; Housley GD; Klugmann M, 2017, 'In vivo characterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL', Neurobiology of Disease, 97, pp. 24 - 35, http://dx.doi.org/10.1016/j.nbd.2016.10.008

Przybyla M; Stevens CH; van der Hoven J; Harasta A; Bi M; Ittner A; van Hummel A; Hodges JR; Piguet O; Karl T; Kassiou M; Housley GD; Ke YD; Ittner LM; Eersel JV, 2016, 'Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia', Neuroscience Letters, 631, pp. 24 - 29, http://dx.doi.org/10.1016/j.neulet.2016.08.007

Craig AJ; Housley GD, 2016, 'Evaluation of gene therapy as an intervention strategy to treat brain injury from stroke', Frontiers in Molecular Neuroscience, 9, pp. 34, http://dx.doi.org/10.3389/fnmol.2016.00034

Browne CJ; Pinyon JL; Housley DM; Crawford EN; Lovell NH; Klugmann M; Housley GD, 2016, 'Mapping of bionic array electric field focusing in plasmid DNA-based gene electrotransfer', Gene Therapy, 23, pp. 369 - 379, http://dx.doi.org/10.1038/gt.2016.8

Housley GD, 2016, 'Keeping the noise down', Australasian Science, pp. 36 - 38

Morton-Jones RT; Vlajkovic SM; Thorne PR; Cockayne DA; Ryan AF; Housley GD, 2015, 'Properties of ATP-gated ion channels assembled from P2X2 subunits in mouse cochlear Reissner’s membrane epithelial cells', Purinergic Signalling, 11, pp. 551 - 560, http://dx.doi.org/10.1007/s11302-015-9473-4

Harasta AE; Power JM; Von Jonquieres G; Karl T; Drucker DJ; Housley GD; Schneider M; Klugmann M, 2015, 'Septal glucagon-like peptide 1 receptor expression determines suppression of cocaine-induced behavior', Neuropsychopharmacology, 40, pp. 1969 - 1978, http://dx.doi.org/10.1038/npp.2015.47

Canales CP; Wong ACY; Gunning PW; Housley GD; Hardeman EC; Palmer SJ, 2015, 'The role of GTF2IRD1 in the auditory pathology of Williams-Beuren Syndrome', European Journal of Human Genetics, 23, pp. 774 - 780, http://dx.doi.org/10.1038/ejhg.2014.188

Froud KE; Wong ACY; Cederholm JME; Klugmann M; Sandow SL; Julien J-P; Ryan AF; Housley GD, 2015, 'Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier', Nature Communications, 6, pp. 7115, http://dx.doi.org/10.1038/ncomms8115

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