By Scientia Professor Matthew Colm Kiernan

Journal articles

Tu S; Li T; Carroll AS; Mahoney CJ; Huynh W; Park SB; Henderson R; Vucic S; Kiernan MC; Lin CSY, 2024, 'Central neurodegeneration in Kennedy’s disease accompanies peripheral motor dysfunction', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-69393-5

van den Bos MAJ; Menon P; Pavey N; Higashihara M; Kiernan MC; Vucic S, 2024, 'Direct interrogation of cortical interneuron circuits in amyotrophic lateral sclerosis.', Brain, http://dx.doi.org/10.1093/brain/awae317

Timmins HC; Thompson AE; Kiernan MC, 2024, 'Diagnostic criteria for amyotrophic lateral sclerosis', Current Opinion in Neurology, 37, pp. 570 - 576, http://dx.doi.org/10.1097/WCO.0000000000001302

Kiernan MC; Kaji R, 2024, 'Emerging concepts and therapies for amyotrophic lateral sclerosis', Current Opinion in Neurology, 37, pp. 558 - 559, http://dx.doi.org/10.1097/WCO.0000000000001308

Tu S; Vucic S; Kiernan MC, 2024, 'Pathological insights derived from neuroimaging in amyotrophic lateral sclerosis: Emerging clinical applications', Current Opinion in Neurology, 37, pp. 577 - 584, http://dx.doi.org/10.1097/WCO.0000000000001295

Devenney EM; Anh N Nguyen Q; Tse NY; Kiernan MC; Tan RH, 2024, 'A scoping review of the unique landscape and challenges associated with dementia in the Western Pacific region', The Lancet Regional Health - Western Pacific, 50, http://dx.doi.org/10.1016/j.lanwpc.2024.101192

Timmins HC; Mok VCT; Kim SH; Shahrizaila N; Sung JY; Sobue G; Agustini S; Ward S; Anstey KJ; Talbot DL; Mazumder S; Tu S; Tan RH; Shin-Yi Lin C; O'Callaghan C; Michaelian JC; Jeon YH; Foxe D; Naismith SL; Piguet O; Ahmed R; Devenney E; Park SB; Kiernan MC, 2024, 'Regional health priorities for dementia: a roadmap for the Western Pacific', The Lancet Regional Health - Western Pacific, 50, http://dx.doi.org/10.1016/j.lanwpc.2024.101179

Clarke AJ; Brodtmann A; Irish M; Mowszowski L; Radford K; Naismith SL; Mok VCT; Kiernan MC; Halliday GM; Ahmed RM, 2024, 'Risk factors for the neurodegenerative dementias in the Western Pacific region', The Lancet Regional Health - Western Pacific, 50, http://dx.doi.org/10.1016/j.lanwpc.2024.101051

Li T; Timmins HC; Mahfouz FM; Trinh T; Mizrahi D; Horvath LG; Harrison M; Grimison P; Friedlander M; Marx G; Boyle F; Wyld D; Henderson R; King T; Baron-Hay S; Kiernan MC; Rutherford C; Goldstein D; Park SB, 2024, 'Validity of Patient-Reported Outcome Measures in Evaluating Nerve Damage Following Chemotherapy', JAMA Network Open, 7, pp. e2424139, http://dx.doi.org/10.1001/jamanetworkopen.2024.24139

Rahiman K J, 2024, 'Chemotherapy-Induced Neurotoxicity', International Journal of Science and Research (IJSR), 13, pp. 1250 - 1254, http://dx.doi.org/10.21275/sr24820170848

Pavey NA; Menon P; Peterchev AV; Kiernan MC; Vucic S, 2024, 'Abnormalities of cortical stimulation strength-duration time constant in amyotrophic lateral sclerosis', Clinical Neurophysiology, 164, pp. 161 - 167, http://dx.doi.org/10.1016/j.clinph.2024.05.014

Pavey N; Hannaford A; Van Den Bos M; Kiernan MC; Menon P; Vucic S, 2024, 'Distinct neuronal circuits mediate cortical hyperexcitability in amyotrophic lateral sclerosis', Brain, 147, pp. 2344 - 2356, http://dx.doi.org/10.1093/brain/awae049

Gray E; Menadue C; Piper A; Wong K; Yee B; Kiernan M, 2024, 'Hypercapnia is not excluded by normoxia in neuromuscular disease patients: implications for oximetry', ERJ Open Research, 10, http://dx.doi.org/10.1183/23120541.00927-2023

Dharmadasa T; Pavey N; Tu S; Menon P; Huynh W; Mahoney CJ; Timmins HC; Higashihara M; van den Bos M; Shibuya K; Kuwabara S; Grosskreutz J; Kiernan MC; Vucic S, 2024, 'Novel approaches to assessing upper motor neuron dysfunction in motor neuron disease/amyotrophic lateral sclerosis: IFCN handbook chapter', Clinical Neurophysiology, 163, pp. 68 - 89, http://dx.doi.org/10.1016/j.clinph.2024.04.010

Higashihara M; Pavey N; Menon P; van den Bos M; Shibuya K; Kuwabara S; Kiernan MC; Koinuma M; Vucic S, 2024, 'Reduction in short interval intracortical inhibition from the early stage reflects the pathophysiology in amyotrophic lateral sclerosis: A meta-analysis study', European Journal of Neurology, 31, http://dx.doi.org/10.1111/ene.16281

Besomi M; Devecchi V; Falla D; McGill K; Kiernan MC; Merletti R; van Dieën JH; Tucker K; Clancy EA; Søgaard K; Hug F; Carson RG; Perreault E; Gandevia S; Besier T; Rothwell JC; Enoka RM; Holobar A; Disselhorst-Klug C; Wrigley T; Lowery M; Farina D; Hodges PW, 2024, 'Consensus for experimental design in electromyography (CEDE) project: Checklist for reporting and critically appraising studies using EMG (CEDE-Check)', Journal of Electromyography and Kinesiology, 76, http://dx.doi.org/10.1016/j.jelekin.2024.102874

Li T; Timmins HC; Mahfouz FM; Mizrahi D; Horvath L; Harrison ML; Grimison PS; Friedlander M; Marx GM; Boyle FM; Wyld D; Henderson R; King T; Baron-Hay SE; Kiernan MC; Rutherford C; Goldstein D; Park SB, 2024, 'Identifying optimized assessment of nerve damage during chemotherapy.', Journal of Clinical Oncology, 42, pp. 12016 - 12016, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.12016

Li T; Trinh T; Bosco A; Kiernan MC; Goldstein D; Park SB, 2024, 'Characterising vincristine-induced peripheral neuropathy in adults: symptom development and long-term persistent outcomes', Supportive Care in Cancer, 32, http://dx.doi.org/10.1007/s00520-024-08484-5

Eisen A; Pioro EP; Goutman SA; Kiernan MC, 2024, 'Nanoplastics and Neurodegeneration in ALS', Brain Sciences, 14, http://dx.doi.org/10.3390/brainsci14050471

Silsby M; Yiannikas C; Fois AF; Kennerson ML; Kiernan MC; Fung VSC; Vucic S, 2024, 'Upper and lower limb tremor in Charcot–Marie–Tooth neuropathy type 1A and the implications for standing balance', Journal of Neurology, 271, pp. 1776 - 1786, http://dx.doi.org/10.1007/s00415-023-12124-z

Carroll AS; Park SB; Lin CSY; Taylor MS; Kwok F; Simon NG; Reilly MM; Kiernan MC; Vucic S, 2024, 'Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis', Clinical Neurophysiology, 159, pp. 81 - 95, http://dx.doi.org/10.1016/j.clinph.2024.01.006

Eisen A; Nedergaard M; Gray E; Kiernan MC, 2024, 'The glymphatic system and Amyotrophic lateral sclerosis', Progress in Neurobiology, 234, http://dx.doi.org/10.1016/j.pneurobio.2024.102571

Silsby M; Yiannikas C; Fois AF; Kiernan MC; Fung VSC; Vucic S, 2024, 'Upper and lower limb tremor in inflammatory neuropathies', Clinical Neurophysiology, 158, pp. 69 - 78, http://dx.doi.org/10.1016/j.clinph.2023.12.005

Ziser L; van Eijk RPA; Kiernan MC; McRae A; Henderson RD; Schultz D; Needham M; Mathers S; McCombe P; Talman P; Vucic S, 2024, 'Amyotrophic lateral sclerosis established as a multistep process across phenotypes', European Journal of Neurology, http://dx.doi.org/10.1111/ene.16532

Eisen A; Vucic S; Kiernan MC, 2024, 'Amyotrophic lateral sclerosis represents corticomotoneuronal system failure', Muscle and Nerve, http://dx.doi.org/10.1002/mus.28290

Devenney EM; Tse NY; O’Callaghan C; Kumfor F; Ahmed RM; Caga J; Hazelton JL; Carrick J; Halliday GM; Piguet O; Kiernan MC; Hodges JR, 2024, 'An attentional and working memory theory of hallucination vulnerability in frontotemporal dementia', Brain Communications, 6, http://dx.doi.org/10.1093/braincomms/fcae123

J M Dick T; Tucker K; Hug F; Besomi M; van Dieën JH; Enoka RM; Besier T; Carson RG; Clancy EA; Disselhorst-Klug C; Falla D; Farina D; Gandevia S; Holobar A; Kiernan MC; Lowery M; McGill K; Merletti R; Perreault E; Rothwell JC; Søgaard K; Wrigley T; Hodges PW, 2024, 'Consensus for experimental design in electromyography (CEDE) project: Application of EMG to estimate muscle force', Journal of Electromyography and Kinesiology, pp. 102910, http://dx.doi.org/10.1016/j.jelekin.2024.102910

Carroll AS; Razvi Y; O’Donnell L; Veleva E; Heslegrave A; Zetterberg H; Vucic S; Kiernan MC; Rossor AM; Gillmore JD; Reilly MM, 2024, 'Serum neurofilament light chain in hereditary transthyretin amyloidosis: validation in real-life practice', Amyloid, 31, pp. 95 - 104, http://dx.doi.org/10.1080/13506129.2024.2313218

Henden L; Fearnley LG; Southwood D; Smith A; Rowe DB; Kiernan MC; Pamphlett R; Bahlo M; Blair IP; Williams KL, 2024, 'Short tandem repeat expansions in LRP12 are absent in cohorts of familial and sporadic amyotrophic lateral sclerosis patients of European ancestry', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 25, pp. 644 - 647, http://dx.doi.org/10.1080/21678421.2024.2348636

Kiernan MC; Davis SM, 2024, 'Stroke is not optional for neurologists', Practical Neurology, http://dx.doi.org/10.1136/pn-2024-004230

Kiernan M, 2024, 'Re: "The Knot Releasing Sutures".', Ophthalmic Plast Reconstr Surg, 40, pp. 111 - 112, http://dx.doi.org/10.1097/IOP.0000000000002577

Tan RH; McCann H; Shepherd CE; Pinkerton M; Mazumder S; Devenney EM; Adler GL; Rowe DB; Kril J; Halliday GM; Kiernan MC, 2023, 'Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis', Acta Neuropathologica Communications, 11, http://dx.doi.org/10.1186/s40478-023-01670-2

Kiernan MC; Halliday GM; Rowe DB; Tan RH, 2023, 'The importance of patient-centred drug development for amyotrophic lateral sclerosis', Neuropathology and Applied Neurobiology, 49, http://dx.doi.org/10.1111/nan.12944

Pavey N; Hannaford A; Higashihara M; van den Bos M; Kiernan MC; Menon P; Vucic S, 2023, 'Utility of split hand index with different motor unit number estimation techniques in ALS', Clinical Neurophysiology, 156, pp. 175 - 182, http://dx.doi.org/10.1016/j.clinph.2023.09.018

Kiernan MC; Farrar MA, 2023, 'Emerging role for sphingolipids in the genetics of amyotrophic lateral sclerosis', Journal of Neurology, Neurosurgery and Psychiatry, 95, pp. 101 - 102, http://dx.doi.org/10.1136/jnnp-2023-332719

Li T; Kandula T; Cohn RJ; Kiernan MC; Park SB; Farrar MA, 2023, 'Prospective assessment of vincristine-induced peripheral neuropathy in paediatric acute lymphoblastic leukemia', Clinical Neurophysiology, 154, pp. 157 - 168, http://dx.doi.org/10.1016/j.clinph.2023.08.002

Silsby M; Yiannikas C; Fois AF; Ng K; Kiernan MC; Fung VSC; Vucic S, 2023, 'Imbalance and lower limb tremor in chronic inflammatory demyelinating polyradiculoneuropathy', Journal of the Peripheral Nervous System, 28, pp. 415 - 424, http://dx.doi.org/10.1111/jns.12574

Farrar MA; Kiernan MC; Kariyawasam DS, 2023, 'Presymptomatic spinal muscular atrophy: a cautionary approach to the proposed new terminology', Brain, 146, pp. E65 - E66, http://dx.doi.org/10.1093/brain/awad061

Pinkerton M; Lourenco G; Pacheco MT; Halliday GM; Kiernan MC; Tan RH, 2023, 'Survival in sporadic ALS is associated with lower p62 burden in the spinal cord', Journal of Neuropathology and Experimental Neurology, 82, pp. 769 - 773, http://dx.doi.org/10.1093/jnen/nlad051

Timmins HC; Vucic S; Kiernan MC, 2023, 'Cortical hyperexcitability in amyotrophic lateral sclerosis: from pathogenesis to diagnosis', Current Opinion in Neurology, 36, pp. 353 - 359, http://dx.doi.org/10.1097/WCO.0000000000001162

Kiernan MC; Park SB, 2023, 'Hyperexcitability, neurodegeneration, and disease progression in amyotrophic lateral sclerosis', Muscle and Nerve, 68, pp. 103 - 105, http://dx.doi.org/10.1002/mus.27843

Yang Y; Rowe D; McCann H; Shepherd CE; Kril JJ; Kiernan MC; Halliday GM; Tan RH, 2023, 'Treatment with the copper compound CuATSM has no significant effect on motor neuronal pathology in patients with ALS', Neuropathology and Applied Neurobiology, 49, http://dx.doi.org/10.1111/nan.12919

Willemse SW; Harley P; Van Eijk RPA; Demaegd KC; Zelina P; Pasterkamp RJ; Van Damme P; Ingre C; Van Rheenen W; Veldink JH; Kiernan MC; Al-Chalabi A; Van Den Berg LH; Fratta P; Van Es MA, 2023, 'UNC13A in amyotrophic lateral sclerosis: From genetic association to therapeutic target', Journal of Neurology, Neurosurgery and Psychiatry, 94, pp. 649 - 656, http://dx.doi.org/10.1136/jnnp-2022-330504

Barshak MB; Pineda R, 2023, 'Case 14-2023: A Man with Redness of the Right Eye. Reply.', N Engl J Med, 389, pp. 383 - 384, http://dx.doi.org/10.1056/NEJMc2307114

Kiernan MF; Gillmore JD; Gupta T, 2023, 'Slowly progressive descending facial nerve paralysis indicates hereditary gelsolin amyloidosis.', Lancet, 401, pp. 2072, http://dx.doi.org/10.1016/S0140-6736(23)01063-2

Vucic S; Stanley Chen KH; Kiernan MC; Hallett M; Benninger DH; Di Lazzaro V; Rossini PM; Benussi A; Berardelli A; Currà A; Krieg SM; Lefaucheur JP; Long Lo Y; Macdonell RA; Massimini M; Rosanova M; Picht T; Stinear CM; Paulus W; Ugawa Y; Ziemann U; Chen R, 2023, 'Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee', Clinical Neurophysiology, 150, pp. 131 - 175, http://dx.doi.org/10.1016/j.clinph.2023.03.010

Menon P; Pavey N; Aberra AS; van den Bos MAJ; Wang R; Kiernan MC; Peterchev AV; Vucic S, 2023, 'Dependence of cortical neuronal strength-duration properties on TMS pulse shape', Clinical Neurophysiology, 150, pp. 106 - 118, http://dx.doi.org/10.1016/j.clinph.2023.03.012

Vucic S; Menon P; Huynh W; Mahoney C; Ho KS; Hartford A; Rynders A; Evan J; Evan J; Ligozio S; Glanzman R; Hotchkin MT; Kiernan MC, 2023, 'Efficacy and safety of CNM-Au8 in amyotrophic lateral sclerosis (RESCUE-ALS study): a phase 2, randomised, double-blind, placebo-controlled trial and open label extension', eClinicalMedicine, 60, http://dx.doi.org/10.1016/j.eclinm.2023.102036

Shimatani Y; Lin CSY; Matamala JM; Kiernan MC, 2023, 'Strength-duration properties and excitability of motor and sensory axons across different target thresholds', Journal of Neurophysiology, 129, pp. 1434 - 1446, http://dx.doi.org/10.1152/jn.00456.2022

Kiernan MC; Burke D; Tan RH, 2023, 'The lower motor neuron homunculus: function matters', Brain, 146, pp. E34 - E35, http://dx.doi.org/10.1093/brain/awad021

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