By Scientia Professor Matthew Colm Kiernan

Preprints

Zussa ZN; Smith AN; van Vugt JJFA; O’Shaughnessy DS; Grima N; Chan Moi Fat S; Blair IP; Rowe DB; Pamphlett R; Nicholson GA; Kiernan MCK; van Rheenen W; Veldink J; Williams KL; Henden L, 2026, Characterising the motif composition and allele length distribution of ZFHX3 GGC repeat expansions in amyotrophic lateral sclerosis, http://dx.doi.org/10.64898/2026.03.09.26347973

Wang X; Barnett M; Boonstra F; Barnett Y; Cabezas M; D'Souza A; Kiernan MC; Kyle K; Law M; Masters L; Tang Z; Tisch S; Tu S; Van Der Walt A; Wang D; Calamante F; Cai W; Wang C, 2025, From Promise to Practical Reality: Transforming Diffusion MRI Analysis with Fast Deep Learning Enhancement, http://dx.doi.org/10.48550/arxiv.2508.10950

Willemse SW; Roes KCB; Damme PV; Hardiman O; Ingre C; Povedano M; Wray N; Gijzen M; de Pagter M; Demaegd K; Janse AFC; Vink R; Sleutjes BTHM; Chiò A; Corcia P; Reviers E; Al-Chalabi A; Kiernan M; Berg LVD; Es MV; Eijk RPAV, 2022, Lithium carbonate in Amyotrophic Lateral Sclerosis patients homozygous for the C-allele at SNP rs12608932 in UNC13A; protocol for a confirmatory, randomized, group-sequential, event-driven, double-blind, placebo-controlled trial., http://dx.doi.org/10.21203/rs.3.rs-2125381/v1

Gold J; Rowe DB; Kiernan MC; Vucic S; Mathers S; van Eijk RP; Nath A; Montojo MG; Norato G; Santamaria UA; Rogers M-L; Malaspina A; Lombardi V; Mehta PR; Westeneng H-J; van den Berg LH; Al-Chalabi A, 2019, Safety and Tolerability of Triumeq in Amyotrophic Lateral Sclerosis: The Lighthouse Trial, http://dx.doi.org/10.2139/ssrn.3347916

Project MinE ALS Sequencing Consortium , 2018, The Project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public, http://dx.doi.org/10.1101/377911

Ribeiro FL; Zhu X; Ye X; Tu S; Ngo ST; Henderson RD; Steyn FJ; Kiernan MC; Barth M; Bollmann S; Shaw TB, An Annotated Multi-Site and Multi-Contrast Magnetic Resonance Imaging Dataset for the study of the Human Tongue Musculature, http://dx.doi.org/10.1101/2024.12.09.24318591

van Rheenen W; van der Spek RAA; Bakker MK; van Vugt JJFA; Hop PJ; Zwamborn RAJ; de Klein N; Westra H-J; Bakker OB; Deelen P; Shireby G; Hannon E; Moisse M; Baird D; Restuadi R; Dolzhenko E; Dekker AM; Gawor K; Westeneng H-J; Tazelaar GHP; van Eijk KR; Kooyman M; Byrne RP; Doherty M; Heverin M; Al Khleifat A; Iacoangeli A; Shatunov A; Ticozzi N; Cooper-Knock J; Smith BN; Gromicho M; Chandran S; Pal S; Morrison KE; Shaw PJ; Hardy J; Orrell RW; Sendtner M; Meyer T; Başak N; van der Kooi AJ; Ratti A; Fogh I; Gellera C; Pinter GL; Corti S; Cereda C; Sproviero D; D’Alfonso S; Sorarù G; Siciliano G; Filosto M; Padovani A; Chiò A; Calvo A; Moglia C; Brunetti M; Canosa A; Grassano M; Beghi E; Pupillo E; Logroscino G; Nefussy B; Osmanovic A; Nordin A; Lerner Y; Zabari M; Gotkine M; Baloh RH; Bell S; Vourc’h P; Corcia P; Couratier P; Millecamps S; Meininger V; Salachas F; Pardina JSM; Assialioui A; Rojas-García R; Dion P; Ross JP; Ludolph AC; Weishaupt JH; Brenner D; Freischmidt A; Bensimon G; Brice A; Dürr A; Payan CAM; Saker-Delye S; Wood N; Topp S; Rademakers R; Tittmann L; Lieb W; Franke A; Ripke S; Braun A; Kraft J; Whiteman DC; Olsen CM; Uitterlinden AG; Hofman A; Rietschel M; Cichon S; Nöthen MM; Amouyel P; Consortium S; Consortium P; Consortium S; Consortium S; Traynor B; Singleton AB; Neto MM; Cauchi RJ; Ophoff RA; Wiedau-Pazos M; Lomen-Hoerth C; van Deerlin VM; Grosskreutz J; Rödiger A; Gaur N; Jörk A; Barthel T; Theele E; Ilse B; Stubendorff B; Witte OW; Steinbach R; Hübner CA; Graff C; Brylev L; Fominykh V; Demeshonok V; Ataulina A; Rogelj B; Koritnik B; Zidar J; Ravnik-Glavač M; Glavač D; Stević Z; Drory V; Povedano M; Blair IP; Kiernan MC; Benyamin B; Henderson RD; Furlong S; Mathers S; McCombe PA; Needham M; Ngo ST; Nicholson GA; Pamphlett R; Rowe DB; Steyn FJ; Williams KL; Mather K; Sachdev PS; Henders AK; Wallace L; de Carvalho M; Pinto S; Petri S; Osmanovic A; Weber M; Rouleau GA; Silani V; Curtis C; Breen G; Glass J; Brown RH; Landers JE; Shaw CE; Andersen PM; Groen EJN; van Es MA; Pasterkamp RJ; Fan D; Garton FC; McRae AF; Smith GD; Gaunt TR; Eberle MA; Mill J; McLaughlin RL; Hardiman O; Kenna KP; Wray NR; Tsai E; Runz H; Franke L; Al-Chalabi A; Van Damme P; van den Berg LH; Veldink JH, Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, http://dx.doi.org/10.1101/2021.03.12.21253159

Rheenen WV; Spek RVD; Bakker M; Berg LVD; Veldink J; Vugt JV; Hop P; Zwamborn R; de Klein N; Westra H-J; Bakker O; Deelen P; Shireby G; Hannon E; Moisse M; Baird D; Restuadi R; Dolzhenko E; Dekker A; Gawor K; Westeneng H-J; Tazelaar G; Eijk KV; Kooyman M; Byrne R; Doherty M; Heverin M; Khleifat AA; Iacoangeli A; Shatunov A; Ticozzi N; Cooper-Knock J; Smith B; Gromicho M; Chandran S; Pal S; Morrison K; Shaw P; Hardy J; Orrell R; Sendtner M; Meyer T; Basak N; Kooi AVD; Ratti A; Fogh I; Gellera C; Pinter GL; Corti S; Cereda C; Sproviero D; D'Alfonso S; Soraru G; Siciliano G; Filosto M; Padovani A; Chio A; Calvo A; Moglia C; Brunetti M; Canosa A; Grassano M; Beghi E; Pupillo E; Logroscino G; Nefussy B; Osmanovic A; Nordin A; Lerner Y; Zabari M; Gotkine M; Baloh R; Bell S; Vourc'h P; Corcia P; Couratier P; Millecamps S; Meininger V; Salachas F; Pardina JM; Assialioui A; Rojas-García R; Dion P; Ross J; Ludolph A; Weishaupt J; Brenner D; Freischmidt A; Bensimon G; Brice A; Durr A; Payan C; Saker-Delye S; Wood N; Topp S; Rademakers R; Tittmann L; Lieb W; Franke A; Ripke S; Braun A; Kraft J; Whiteman D; Olsen C; Uitterlinden A; Hofman A; Rietschel M; Cichon S; Nöthen M; Amouyel P; Traynor B; Singleton A; Neto MM; Cauchi R; Ophoff R; Wiedau-Pazos M; Lomen-Hoerth C; Deerlin VV; Grosskreutz J; Rödiger A; Jörk A; Barthel T; Theele E; Ilse B; Stubendorff B; Witte O; Steinbach R; Hübner C; Graff C; Brylev L; Fominykh V; Demeshonok V; Ataulina A; Rogelj B; Koritnik B; Zidar J; Ravnik-Glavač M; Glavač D; Stević Z; Drory V; Povedano M; Blair I; Kiernan M; Benyamin B; Henderson R; Furlong S; Mathers S; McCombe P; Needham M; Ngo S; Nicholson G; Pamphlett R; Rowe D; Steyn F; Williams K; Mather K; Sachdev P; Henders A; Wallace L; de Carvalho M; Pinto S; Petri S; Weber M; Rouleau G; Silani V; Curtis C; Breen G; Glass J; Brown R; Landers J; Shaw C; Andersen P; Groen E; Es MV; Pasterkamp J; Fan D; Garton F; McRae A; Smith GD; Gaunt T; Eberle M; Mill J; McLaughlin R; Hardiman O; Kenna K; Wray N; Tsai E; Runz H; Franke L; Al-Chalabi A; Damme PV; Gaur N, Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, http://dx.doi.org/10.21203/rs.3.rs-322430/v1

Haidar M; Viden A; Cuic B; Wang T; Rosier M; Tomas D; Mills SA; Govier-Cole A; Djouma E; Luikinga S; Rytova V; Barton SK; Gonsalvez DG; Palmer LM; McLean C; Kiernan MC; Vucic S; Turner BJ, Cortical hyperexcitability drives dying forward ALS symptoms and pathology in mice, http://dx.doi.org/10.1101/2021.08.13.456320

Byrne RP; van Rheenen W; Consortium PMAG; van den Berg LH; Veldink JH; McLaughlin RL, Dutch population structure across space, time and GWAS design, http://dx.doi.org/10.1101/2020.01.01.892513

Hop PJ; Zwamborn RAJ; Hannon E; Shireby GL; Nabais MF; Walker EM; van Rheenen W; van Vugt JJFA; Dekker AM; Westeneng H-J; Tazelaar GHP; van Eijk KR; Moisse M; Baird D; Al Khleifat A; Iacoangeli A; Ticozzi N; Ratti A; Cooper-Knock J; Morrison KE; Shaw PJ; Basak AN; Chiò A; Calvo A; Moglia C; Canosa A; Brunetti M; Grassano M; Gotkine M; Lerner Y; Zabari M; Vourc’h P; Corcia P; Couratier P; Pardina JSM; Salas T; Dion P; Ross JP; Henderson RD; Mathers S; McCombe PA; Needham M; Nicholson G; Rowe DB; Pamphlett R; Mather KA; Sachdev PS; Furlong S; Garton FC; Henders AK; Lin T; Ngo ST; Steyn FJ; Wallace L; Williams KL; Consortium B; Consortium BM; Neto MM; Cauchi RJ; Blair IP; Kiernan MC; Drory V; Povedano M; de Carvalho M; Pinto S; Weber M; Rouleau G; Silani V; Landers JE; Shaw CE; Andersen PM; McRae AF; van Es MA; Pasterkamp RJ; Wray NR; McLaughlin RL; Hardiman O; Kenna KP; Tsai E; Runz H; Al-Chalabi A; van den Berg LH; Van Damme P; Mill J; Veldink JH, Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways, http://dx.doi.org/10.1101/2021.03.12.21253115

Eftekhari Z; Tu S; Ballard T; Eckstein K; Strasser B; Niess F; Hingerl L; Bogner W; Kiernan MC; Henderson RD; Barth M; Shaw TB, Glutamine and NAA dissociate in ALS across somatotopically defined motor regions using 7T MRSI, http://dx.doi.org/10.64898/2026.07.09.26357702

Henden L; Twine NA; Szul P; McCann EP; Nicholson GA; Rowe DB; Kiernan MC; Bauer DC; Blair IP; Williams KL, IBD analysis of Australian amyotrophic lateral sclerosis SOD1-mutation carriers identifies five founder events and links sporadic cases to existing ALS families, http://dx.doi.org/10.1101/685925

Krishnan D; Talbot D-L; Ashhurst JF; Park SB; Vucic S; Timmins HC; Kiernan MC, Longitudinal Assessment of Cortical Motor Function in Amyotrophic Lateral Sclerosis, http://dx.doi.org/10.21203/rs.3.rs-5816527/v1

Li T; Timmins HC; Horvath LG; Harrison M; Grimison P; Friedlander M; Marx G; Boyle F; Wyld D; Henderson R; King T; Baron-Hay S; Kiernan MC; Barnes EH; Goldstein D; Park SB, Peripheral Neuropathy in Cancer Patients- Multifactorial Contributors to Dose Limiting and Chronic Toxicity, http://dx.doi.org/10.1101/2024.07.24.24310956

Shaw TB; Ribeiro FL; Zhu X; Aiken P; Bollmann S; Bollmann S; Chang J; Chidley K; Dempsey-Jones H; Eftekhari Z; Gillespie J; Henderson RD; Kiernan MC; Ktena I; McCombe PA; Ngo ST; Taubert ST; Whelan B-M; Ye X; Steyn FJ; Tu S; Barth M, Segmentation of the Human Tongue Musculature Using MRI: Field Guide and Validation in Motor Neuron Disease, http://dx.doi.org/10.1101/2024.12.12.24318964

Eisen A; Kiernan M, The Neonatal Microbiome: Implications for Amyotrophic Lateral Sclerosis, http://dx.doi.org/10.20944/preprints202501.1027.v1

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