By Scientia Professor Vlado Perkovic

Book Chapters

Rahimi K; Perkovic V, 2018, 'Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists' Collaboration', in Hypertension: A Companion to Braunwald's Heart Disease, pp. 433 - 441, http://dx.doi.org/10.1016/B978-0-323-42973-3.00047-0

Rahimi K; Perkovic V, 2018, '47 Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists’ Collaboration', in Hypertension: A Companion to Braunwald's Heart Disease, Elsevier, pp. 433 - 441, http://dx.doi.org/10.1016/b978-0-323-42973-3.00047-0

Jun M; Perkovic V, 2015, 'Fibrates: risk-benefits and role in treating dyslipidemias', in Dyslipidemias Pathophysiology, Evaluation and Management, Humana Press

Wang AY; Jardine M; Perkovic V, 2014, 'Kidney Disease in Diabetes', in Managing Cardiovascular Complications in Diabetes, pp. 58 - 86, http://dx.doi.org/10.1002/9781118337967.ch3

Wang Y; Perkovic V; Jardine M, 2014, 'kidney disease in diabetes', in Managing Cardiovascular Complications in Diabetes, John Wiley & Sons

Wang Y; Ivany JN; Perkovic V; Gallagher MP; Jardine MJ, 2012, 'Anticoagulants and antiplatelet agents for preventing central venous haemodialysis catheter malfunction in patients with end-stage kidney disease', in Wang Y (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd009631

Gangadharan Komala M; Pianta TJ; Jardine MJ; Webster AC; Perkovic V, 2011, 'Interventions for preventing intradialytic hypotension in haemodialysis patients', in Gangadharan Komala M (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd009459

Jun M; Perkovic V; Cass A, 2011, 'Intensive glycemic control and renal outcome', in Diabetes and the Kidney, Karger Medical and Scientific Publishers

Razavian M; Di Micco L; Palmer SC; Craig JC; Perkovic V; Zoungas S; Webster AC; Jardine MJ; Strippoli GFM, 2010, 'Antiplatelet agents for chronic kidney disease', in Palmer SC (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd008834

Badve SV; Beller E; Cass A; Francis DP; Hawley C; Macdougall IC; Perkovic V; Johnson DW, 2010, 'Interventions for erythropoietin-resistant anaemia in dialysis patients', in Badve SV (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd006861.pub2

Perkovic V; Venkataraman V; Cooper B; Zoungas S; Webster AC, 2009, 'Antioxidants for chronic kidney disease', in Perkovic V (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd008176

Gallagher M; Perkovic V; Jardine M; Cass A, 2009, 'Lipid lowering in chronic kidney disease', in Therapeutic Strategies in Lipid Disorders

Perkovic V; Craig JC; Masterson R; Webster A, 2004, 'HMG CoA reductase inhibitors (statins) for kidney transplant recipients', in Perkovic V (ed.), , John Wiley & Sons, Ltd, http://dx.doi.org/10.1002/14651858.cd005019

Journal articles

Patel SM; Kang YM; Im K; Neuen BL; Anker SD; Bhatt DL; Butler J; Cherney DZI; Claggett BL; Fletcher RA; Herrington WG; Inzucchi SE; Jardine MJ; Mahaffey KW; McGuire DK; McMurray JJV; Neal B; Packer M; Perkovic V; Solomon SD; Staplin N; Vaduganathan M; Wanner C; Wheeler DC; Zannad F; Zhao Y; Heerspink HJL; Sabatine MS; Wiviott SD, 2024, 'Sodium Glucose Co-transporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis.', Circulation, http://dx.doi.org/10.1161/CIRCULATIONAHA.124.069568

Trachtman H; Radhakrishnan J; Rheault MN; Alpers CE; Barratt J; Heerspink HJL; Noronha IL; Perkovic V; Rovin B; Trimarchi H; Wong MG; Mercer A; Inrig J; Rote W; Murphy E; Bedard PW; Roth S; Bieler S; Komers R, 2024, 'Focal Segmental Glomerulosclerosis Patient Baseline Characteristics in the Sparsentan Phase 3 DUPLEX Study', Kidney International Reports, 9, pp. 1020 - 1030, http://dx.doi.org/10.1016/j.ekir.2024.01.032

Kim D; Perkovic V; Kotwal S, 2024, 'Barriers to Care: New Medications and CKD', Kidney International Reports, 9, pp. 504 - 507, http://dx.doi.org/10.1016/j.ekir.2023.12.012

Tobe SW; Mavrakanas TA; Bajaj HS; Levin A; Tangri N; Slee A; Neuen BL; Perkovic V; Mahaffey KW; Rapattoni W; Ang FG, 2024, 'Impact of Canagliflozin on Kidney and Cardiovascular Outcomes by Type 2 Diabetes Duration: A Pooled Analysis of the CANVAS Program and CREDENCE Trials', Diabetes Care, 47, pp. 501 - 507, http://dx.doi.org/10.2337/dc23-1450

Ha JT; Freedman SB; Kelly DM; Neuen BL; Perkovic V; Jun M; Badve SV, 2024, 'Kidney Function, Albuminuria, and Risk of Incident Atrial Fibrillation: A Systematic Review and Meta-Analysis', American Journal of Kidney Diseases, 83, pp. 350 - 359.e1, http://dx.doi.org/10.1053/j.ajkd.2023.07.023

Cheung CK; Barratt J; Carroll K; Lafayette RA; Liew A; Suzuki Y; Tesař V; Trimarchi H; Wong MG; Zhang H; Perkovic V; Rizk DV, 2024, 'Targeting APRIL in the Treatment of IgA Nephropathy', Clinical Journal of the American Society of Nephrology, 19, pp. 394 - 398, http://dx.doi.org/10.2215/CJN.0000000000000338

Tangri N; Mathur VS; Bushinsky DA; Klaerner G; Li E; Parsell D; Stasiv Y; Walker M; Wesson DE; Wheeler DC; Perkovic V; Inker LA, 2024, 'VALOR-CKD: A Multicenter, Randomized, Double-Blind Placebo-Controlled Trial Evaluating Veverimer in Slowing Progression of CKD in Patients with Metabolic Acidosis', Journal of the American Society of Nephrology, 35, pp. 311 - 320, http://dx.doi.org/10.1681/ASN.0000000000000292

Cunningham JW; Claggett BL; Lopes RD; McMurray JJV; Perkovic V; Carroll K; Hiemstra T; Khavandi K; Lukas MA; Ranganathan P; Shannon J; van Adelsberg J; Singh AK; Solomon SD, 2024, 'Daprodustat and Heart Failure in CKD.', J Am Soc Nephrol, http://dx.doi.org/10.1681/ASN.0000000000000321

Heerspink HJL; Stack AG; Terkeltaub R; Jongs N; Inker LA; Bjursell M; Maklad N; Perl S; Eklund O; Rikte T; Sjöström CD; Perkovic V; SAPPHIRE Investigators , 2024, 'Combination Treatment with Verinurad and Allopurinol in CKD: A Randomized Placebo and Active Controlled Trial.', J Am Soc Nephrol, http://dx.doi.org/10.1681/ASN.0000000000000326

Marx N; Kolkailah AA; Rosenstock J; Johansen OE; Cooper ME; Alexander JH; Toto RD; Wanner C; Espeland MA; Mattheus M; Schnaidt S; Perkovic V; Gollop ND; McGuire DK, 2024, 'Hypoglycemia and Cardiovascular Outcomes in the CARMELINA and CAROLINA Trials of Linagliptin A Secondary Analysis of Randomized Clinical Trials', JAMA Cardiology, 9, pp. 134 - 143, http://dx.doi.org/10.1001/jamacardio.2023.4602

Neuen BL; Heerspink HJL; Vart P; Claggett BL; Fletcher RA; Arnott C; de Oliveira Costa J; Falster MO; Pearson SA; Mahaffey KW; Neal B; Agarwal R; Bakris G; Perkovic V; Solomon SD; Vaduganathan M, 2024, 'Estimated Lifetime Cardiovascular, Kidney, and Mortality Benefits of Combination Treatment With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Nonsteroidal MRA Compared With Conventional Care in Patients With Type 2 Diabetes and Albuminuria', Circulation, 149, pp. 450 - 462, http://dx.doi.org/10.1161/CIRCULATIONAHA.123.067584

Sharma A; Razaghizad A; Joury A; Levin A; Bajaj HS; Mancini GBJ; Wong NC; Slee A; Ang FG; Rapattoni W; Neuen BL; Arnott C; Perkovic V; Mahaffey KW, 2024, 'Primary and Secondary Cardiovascular and Kidney Prevention With Canagliflozin: Insights From the CANVAS Program and CREDENCE Trial', Journal of the American Heart Association, 13, http://dx.doi.org/10.1161/JAHA.123.031586

Neuen BL; Jun M; Wick J; Kotwal S; Badve SV; Jardine MJ; Gallagher M; Chalmers J; Nallaiah K; Perkovic V; Peiris D; Rodgers A; Woodward M; Ronksley PE, 2024, 'Estimating the population-level impacts of improved uptake of SGLT2 inhibitors in patients with chronic kidney disease: a cross-sectional observational study using routinely collected Australian primary care data', The Lancet Regional Health - Western Pacific, 43, http://dx.doi.org/10.1016/j.lanwpc.2023.100988

Jun M; Wick J; Neuen BL; Kotwal S; Badve SV; Woodward M; Chalmers J; Peiris D; Rodgers A; Nallaiah K; Jardine MJ; Perkovic V; Gallagher M; Ronksley PE, 2024, 'The Prevalence of CKD in Australian Primary Care: Analysis of a National General Practice Dataset', Kidney International Reports, 9, pp. 312 - 322, http://dx.doi.org/10.1016/j.ekir.2023.11.022

Sharma A; Marques P; Neuen BL; Fletcher RA; Slee A; Rapattoni W; Ang FG; Arnott C; Levin A; Verma S; Perkovic V; Mahaffey KW, 2024, 'Timing of statistical benefit of canagliflozin in patients with type 2 diabetes for cardiovascular and heart failure outcomes: Insights from the CANVAS Program and CREDENCE trial', Diabetes, Obesity and Metabolism, 26, pp. 758 - 762, http://dx.doi.org/10.1111/dom.15340

Kotwal S; Perkovic E; Perkovic V, 2024, 'Combination therapy with kidney protective therapies: Optimizing the benefits?', Current Opinion in Nephrology and Hypertension, 33, pp. 136 - 143, http://dx.doi.org/10.1097/MNH.0000000000000929

Zhang H; Rizk DV; Perkovic V; Maes B; Kashihara N; Rovin B; Trimarchi H; Sprangers B; Meier M; Kollins D; Papachristofi O; Milojevic J; Junge G; Nidamarthy PK; Charney A; Barratt J, 2024, 'Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy', Kidney International, 105, pp. 189 - 199, http://dx.doi.org/10.1016/j.kint.2023.09.027

Talbot B; Davies S; Burman J; Ritchie A; Snelling P; Lynch S; Park Y; Jones B; Garvey V; Jaure A; Jardine M; Perkovic V; Gallagher M; Brandwood A; Kaur N; Knight J, 2024, 'The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system', Peritoneal Dialysis International, http://dx.doi.org/10.1177/08968608231209850

Barratt J; Rovin B; Murphy E; Komers R; Trimarchi H; Perkovic V, 2024, 'WCN24-847 SPARSENTAN VS IRBESARTAN IN PATIENTS WITH IMMUNOGLOBULIN A NEPHROPATHY (IgAN): SUBGROUP ANALYSES OF 2-YEAR RESULTS FROM THE PIVOTAL PHASE 3 PROTECT TRIAL', Kidney International Reports, 9, pp. S505 - S506, http://dx.doi.org/10.1016/j.ekir.2024.02.1413

Heerspink HJL; Jongs N; Schloemer P; Little DJ; Brinker M; Tasto C; Karpefors M; Wheeler DC; Bakris G; Perkovic V; Nkulikiyinka R; Rossert J; Gasparyan SB, 2023, 'Development and Validation of a New Hierarchical Composite End Point for Clinical Trials of Kidney Disease Progression', Journal of the American Society of Nephrology, 34, pp. 2025 - 2038, http://dx.doi.org/10.1681/ASN.0000000000000243

Fletcher RA; Jongs N; Chertow GM; McMurray JJV; Arnott C; Jardine MJ; Mahaffey KW; Perkovic V; Rockenschaub P; Rossing P; Correa-Rotter R; Toto RD; Vaduganathan M; Wheeler DC; Heerspink HJL; Neuen BL, 2023, 'Effect of SGLT2 Inhibitors on Discontinuation of Renin–angiotensin System Blockade: A Joint Analysis of the CREDENCE and DAPA-CKD Trials', Journal of the American Society of Nephrology, 34, pp. 1965 - 1975, http://dx.doi.org/10.1681/ASN.0000000000000248

Yu J; Sweeting AN; Gianacas C; Houston L; Lee V; Fletcher RA; Perkovic V; Li Q; Neuen BL; Berwanger O; Heerspink HJL; de Zeeuw D; Arnott C, 2023, 'The effects of canagliflozin in type 2 diabetes in subgroups defined by population-specific body mass index: Insights from the CANVAS Program and CREDENCE trial', Diabetes, Obesity and Metabolism, 25, pp. 3724 - 3735, http://dx.doi.org/10.1111/dom.15267

Marx N; Deanfield JE; Gerward S; Hovingh GK; Plunde O; Pratley RE; Staerk-Ostergaard J; Perkovic V, 2023, 'Prevalence of systemic inflammation in individuals with atherosclerotic cardiovascular disease: baseline characteristics from the SELECT, SOUL and FLOW phase 3 trials of semaglutide', European Heart Journal, 44, http://dx.doi.org/10.1093/eurheartj/ehad655.2751

Neuen BL; Perkovic V; Bakris GL; Lambers Heerspink H; Vaduganathan M, 2023, 'Abstract 17437: Estimated Lifetime Benefits of Combination Therapy With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Non-Steroidal MRAs in Patients With Type 2 Diabetes and Albuminuria', Circulation, 148, http://dx.doi.org/10.1161/circ.148.suppl_1.17437

Heerspink HJL; Vart P; Jongs N; Neuen BL; Bakris G; Claggett B; Vaduganathan M; McCausland F; Docherty KF; Jhund PS; Solomon SD; Perkovic V; McMurray JJV, 2023, 'Estimated lifetime benefit of novel pharmacological therapies in patients with type 2 diabetes and chronic kidney disease: A joint analysis of randomized controlled clinical trials', Diabetes, Obesity and Metabolism, 25, pp. 3327 - 3336, http://dx.doi.org/10.1111/dom.15232

Rossing P; Baeres FMM; Bakris G; Bosch-Traberg H; Gislum M; Gough SCL; Idorn T; Lawson J; Mahaffey KW; Mann JFE; Mersebach H; Perkovic V; Tuttle K; Pratley R, 2023, 'The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease', Nephrology Dialysis Transplantation, 38, pp. 2041 - 2051, http://dx.doi.org/10.1093/ndt/gfad009

Januzzi JL; Mohebi R; Liu Y; Sattar N; Heerspink HJL; Tefera E; Vaduganathan M; Butler J; Yavin Y; Li J; Pollock CA; Perkovic V; Neal B; Hansen MK, 2023, 'Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial', Circulation, 148, pp. 651 - 660, http://dx.doi.org/10.1161/CIRCULATIONAHA.123.065251

Singh AK; Mccausland FR; Claggett BL; Wanner C; Wiecek A; Atkins MB; Carroll K; Perkovic V; Mcmurray JJV; Wittes J; Snapinn S; Blackorby A; Meadowcroft A; Barker T; Dimino T; Mallett S; Cobitz AR; Solomon SD, 2023, 'Analysis of on-treatment cancer safety events with daprodustat versus conventional erythropoiesis-stimulating agents - post hoc analyses of the ASCEND-ND and ASCEND-D trials', Nephrology Dialysis Transplantation, 38, pp. 1890 - 1897, http://dx.doi.org/10.1093/ndt/gfac342

Sridhar VS; Neuen BL; Fletcher RA; Slee A; Ang FG; Rapattoni W; Arnott C; Cherney DZ; Perkovic V; Wheeler DC; Levin A, 2023, 'Kidney protection with canagliflozin: A combined analysis of the randomized CANVAS program and CREDENCE trials', Diabetes, Obesity and Metabolism, 25, pp. 2331 - 2339, http://dx.doi.org/10.1111/dom.15112

Kang A; Smyth B; Neuen BL; Heerspink HJL; Di Tanna GL; Zhang H; Arnott C; Hockham C; Agarwal R; Bakris G; Charytan DM; de Zeeuw D; Greene T; Levin A; Pollock C; Wheeler DC; Mahaffey KW; Perkovic V; Jardine MJ, 2023, 'The sodium-glucose cotransporter-2 inhibitor canagliflozin does not increase risk of non-genital skin and soft tissue infections in people with type 2 diabetes mellitus: A pooled post hoc analysis from the CANVAS Program and CREDENCE randomized double-blind trials', Diabetes, Obesity and Metabolism, 25, pp. 2151 - 2162, http://dx.doi.org/10.1111/dom.15091

Fletcher RA; Arnott C; Rockenschaub P; Schutte AE; Carpenter L; Vaduganathan M; Agarwal R; Bakris G; Chang TI; Heerspink HJL; Jardine MJ; Mahaffey KW; Neal B; Pollock C; Jun M; Rodgers A; Perkovic V; Neuen BL, 2023, 'Canagliflozin, Blood Pressure Variability, and Risk of Cardiovascular, Kidney, and Mortality Outcomes: Pooled Individual Participant Data From the CANVAS and CREDENCE Trials', Journal of the American Heart Association, 12, pp. e028516, http://dx.doi.org/10.1161/JAHA.122.028516

Inker LA; Collier W; Greene T; Miao S; Chaudhari J; Appel GB; Badve SV; Caravaca-Fontán F; Del Vecchio L; Floege J; Goicoechea M; Haaland B; Herrington WG; Imai E; Jafar TH; Lewis JB; Li PKT; Maes BD; Neuen BL; Perrone RD; Remuzzi G; Schena FP; Wanner C; Wetzels JFM; Woodward M; Heerspink HJL; Estacio RO; Hanratty R; Chalmers J; Canetta P; Barrett B; Neal B; Perkovic V; Mahaffey KW; Johnson D; Jardine M; von Eynatten M; Verde E; Verdalles U; Arroyo D; Chapman A; Torres V; Yu A; Brosnahan G; Hannedouche T; Chow KM; Szeto CC; Leung CB; Xie D; Hou FF; Dwyer J; Pohl MA; Raz I; Hunsicker LG; Vanacker A; Malfait T; Maschio G; Locatelli F; Blankestijn PJ; van Zuilen A; Kobayashi F; Makino H; Chan JCN; Andrulli S; Pozzi C; Casartelli D; Praga M; Trujillo H; Cavero T; Sevillano A; Ruggenenti P; Perna A; Carrara F; Keane WF; Manno C; Haynes R; Herrington WG; Baigent C; Landray M; Rauen T; Seikrit C; Wied S; Toto RD; de Jong PE; Saddelli M, 2023, 'A meta-analysis of GFR slope as a surrogate endpoint for kidney failure', Nature Medicine, 29, pp. 1867 - 1876, http://dx.doi.org/10.1038/s41591-023-02418-0

Yi TW; Wong MMY; Neuen BL; Arnott C; Poirier P; Seufert J; Slee A; Rapattoni W; Ang FG; Wheeler DC; Mahaffey KW; Perkovic V; Levin A, 2023, 'Effects of canagliflozin on cardiovascular and kidney events in patients with chronic kidney disease with and without peripheral arterial disease: Integrated analysis from the CANVAS Program and CREDENCE trial', Diabetes, Obesity and Metabolism, 25, pp. 2043 - 2047, http://dx.doi.org/10.1111/dom.15065

Heerspink HJL; Jongs N; Neuen BL; Schloemer P; Vaduganathan M; Inker LA; Fletcher RA; Wheeler DC; Bakris G; Greene T; Chertow GM; Perkovic V, 2023, 'Effects of newer kidney protective agents on kidney endpoints provide implications for future clinical trials', Kidney International, 104, pp. 181 - 188, http://dx.doi.org/10.1016/j.kint.2023.03.037

Yi TW; Smyth B; Di Tanna GL; Arnott C; Cardoza K; Kang A; Pollock C; Agarwal R; Bakris G; Charytan DM; de Zeeuw D; Heerspink HJL; Neal B; Wheeler DC; Cannon CP; Zhang H; Zinman B; Perkovic V; Levin A; Mahaffey KW; Jardine M; Brenner BM; Greene T; Jardine MJ; Meininger G; Li N; Kolesnyk I; Aizenberg D; Pecoits-Filho R; Cherney D; Obrador G; Chertow G; Chang T; Hawley C; Ji L; Wada T; Jha V; Lim SK; Lim-Abrahan MA; Santos F; Chae DW; Hwang SJ; Vazelov E; Rychlík I; Hadjadj S; Krane V; Rosivall L; De Nicola L; Dreval A; Nowicki M; Schiller A; Distiller L; Górriz JL; Kolesnyk M; David ; Wheeler C; Guerrero RAA; Albisu JP; Alvarisqueta A; Bartolacci I; Berli MA; Bordonava A; Calella P; Cantero MC; Cartasegna LR; Cercos E; Coloma GC; Colombo H; Commendatore V; Cuadrado J; Cuneo CA; Cusumano AM; Douthat WG; Dran RD; Farias E; Fernandez MF; Finkelstein H; Fragale G; Fretes JO; Garcia NH; Gastaldi A; Gelersztein E; Glenny JA; Gonzalez JP; Colaso PDCG; Goycoa C; Greloni GC; Guinsburg A; Hermida S; Juncos LI; Klyver MI; Kraft F; Krynski F; Lanchiotti PV; Leon de la Fuente RA; Marchetta N; Mele P; Nicolai S; Novoa PA; Orio SI, 2023, 'Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial', American Journal of Kidney Diseases, 82, pp. 84 - 96.e1, http://dx.doi.org/10.1053/j.ajkd.2022.12.015

Singh AK; Claggett BL; Perkovic V; Hiemstra T; Khavandi K; Lukas MA; Ranganathan P; Shannon JB; van Adelsberg J; Solomon S, 2023, '#3807 HEART FAILURE IN ASCEND-ND AND ASCEND-D', Nephrology Dialysis Transplantation, 38, http://dx.doi.org/10.1093/ndt/gfad063c_3807

Perkovic V; Barratt J; Radhakrishnan J; Rizk D; Trimarchi H; Khawaja Z; Leiske J; Sorensen B; King A; Jones-Burton C; Campbell K, 2023, '#4333 A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF BION-1301 IN ADULTS WITH IGA NEPHROPATHY', Nephrology Dialysis Transplantation, 38, http://dx.doi.org/10.1093/ndt/gfad063c_4333

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