By Scientia Professor Vlado Perkovic

Journal articles

Perkovic V; Craig JC; Chailimpamontree W; Fox CS; Garcia-Garcia G; Benghanem Gharbi M; Jardine MJ; Okpechi IG; Pannu N; Stengel B; Tuttle KR; Uhlig K; Levey AS, 2017, 'Action plan for optimizing the design of clinical trials in chronic kidney disease', Kidney International Supplements, 7, pp. 138 - 144, http://dx.doi.org/10.1016/j.kisu.2017.07.009

Jardine MJ; Kasiske B; Adu D; Alrukhaimi M; Ashuntantang GE; Basnet S; Chailimpamontree W; Craig JC; O'Donoghue DJ; Perkovic V; Powe NR; Roberts CJ; Suzuki Y; Tanaka T; Uhlig K, 2017, 'Closing the gap between evidence and practice in chronic kidney disease', Kidney International Supplements, 7, pp. 114 - 121, http://dx.doi.org/10.1016/j.kisu.2017.07.006

Ren S; Wang Y; Xian L; Toyama T; Jardine M; Li G; Perkovic V; Hong D, 2017, 'Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis', PLoS ONE, 12, pp. e0184398, http://dx.doi.org/10.1371/journal.pone.0184398

Marx N; McGuire DK; Perkovic V; Woerle HJ; Broedl UC; Von Eynatten M; George JT; Rosenstock J, 2017, 'Composite primary end points in cardiovascular outcomes trials involving type 2 diabetes patients: Should unstable angina be included in the primary end point?', Diabetes Care, 40, pp. 1144 - 1151, http://dx.doi.org/10.2337/dc17-0068

Webb DJ; Coll B; Heerspink HJL; Andress D; Pritchett Y; Brennan JJ; Houser M; Correa-Rotter R; Kohan D; Makino H; Perkovic V; Remuzzi G; Tobe SW; Toto R; Busch R; Pergola P; Parving HH; de Zeeuw D, 2017, 'Longitudinal Assessment of the Effect of Atrasentan on Thoracic Bioimpedance in Diabetic Nephropathy: A Randomized, Double-Blind, Placebo-Controlled Trial', Drugs in R and D, 17, pp. 441 - 448, http://dx.doi.org/10.1007/s40268-017-0201-0

Matsushita K; Ballew SH; Coresh J; Arima H; Ärnlöv J; Cirillo M; Ebert N; Hiramoto JS; Kimm H; Shlipak MG; Visseren FLJ; Gansevoort RT; Kovesdy CP; Shalev V; Woodward M; Kronenberg F; Chalmers J; Perkovic V; Grams ME; Sang Y; Schaeffner E; Martus P; Levin A; Djurdjev O; Tang M; Heine G; Seiler S; Zawada A; Emrich I; Sarnak M; Katz R; Brenner H; Schöttker B; Rothenbacher D; Saum KU; Köttgen A; Schneider M; Eckardt KU; Green J; Kirchner HL; Chang AR; Black C; Marks A; Prescott G; Clark L; Fluck N; Jee SH; Mok Y; Chodick G; Wetzels JFM; Blankestijn PJ; van Zuilen AD; Bots M; Peralta C; Hiromoto J; Bottinger E; Nadkarni GN; Ellis SB; Nadukuru R; Kenealy T; Elley CR; Collins JF; Drury PL; Bakker SJ; Heerspink HJL; Jassal SK; Bergstrom J; Ix JH; Barrett-Connor E; Kalantar-Zadeh K; Carrero JJ; Gasparini A; Qureshi AR; Barany P; Algra A; van der Graaf Y; Evans M; Segelmark M; Stendahl M; Schön S; Tangri N; Sud M; Naimark D; Lannfelt L; Larsson A; Hallan S; Levey AS; Chen J; Kwak L, 2017, 'Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data', The Lancet Diabetes and Endocrinology, 5, pp. 718 - 728, http://dx.doi.org/10.1016/S2213-8587(17)30183-3

Neal B; Perkovic V; Mahaffey KW; De Zeeuw D; Fulcher G; Erondu N; Shaw W; Law G; Desai M; Matthews DR, 2017, 'Canagliflozin and cardiovascular and renal events in type 2 diabetes', New England Journal of Medicine, 377, pp. 644 - 657, http://dx.doi.org/10.1056/NEJMoa1611925

Lv J; Zhang H; Wong MG; Jardine MJ; Hladunewich M; Jha V; Monaghan H; Zhao M; Barbour S; Reich H; Cattran D; Glassock R; Levin A; Wheeler D; Woodward M; Billot L; Chan TM; Liu ZH; Johnson DW; Cass A; Feehally J; Floege J; Remuzzi G; Wu Y; Agarwal R; Wang HY; Perkovic V, 2017, 'Effect of oral methylprednisolone on clinical outcomes in patients with IgA nephropathy: The TESTING randomized clinical trial', JAMA - Journal of the American Medical Association, 318, pp. 432 - 442, http://dx.doi.org/10.1001/jama.2017.9362

Patel A; Pieper K; Myburgh JA; Perkovic V; Finfer S; Yang Q; Li Q; Billot L, 2017, 'Reanalysis of the crystalloid versus hydroxyethyl starch trial (CHEST)', New England Journal of Medicine, 377, pp. 298 - 300, http://dx.doi.org/10.1056/NEJMc1703337

Yu J; Zhou Z; McEvoy RD; Anderson CS; Rodgers A; Perkovic V; Neal B, 2017, 'Association of positive airway pressure with cardiovascular events and death in adults with sleep apnea: A systematic review and meta-analysis', JAMA - Journal of the American Medical Association, 318, pp. 156 - 166, http://dx.doi.org/10.1001/jama.2017.7967

Gummer J; Trengove R; Pascoe EM; Badve SV; Cass A; Clarke P; McDonald SP; Morrish AT; Pedagogos E; Perkovic V; Reidlinger D; Scaria A; Walker R; Vergara LA; Hawley CM; Johnson DW; Olynyk JK; Ferrari P, 2017, 'Association between serum hepcidin-25 and primary resistance to erythropoiesis-stimulating agents in chronic kidney disease: a secondary analysis of the HERO trial', Nephrology, 22, pp. 548 - 554, http://dx.doi.org/10.1111/nep.12815

Neal B; Perkovic V; Mahaffey KW; Fulcher G; Erondu N; Desai M; Shaw W; Law G; Walton MK; Rosenthal N; de Zeeuw D; Matthews DR, 2017, 'Optimizing the analysis strategy for the CANVAS Program: A prespecified plan for the integrated analyses of the CANVAS and CANVAS-R trials', Diabetes, Obesity and Metabolism, 19, pp. 926 - 935, http://dx.doi.org/10.1111/dom.12924

Jardine MJ; Zuo L; Gray NA; De Zoysa JR; Chan CT; Gallagher MP; Monaghan H; Grieve SM; Puranik R; Lin H; Eris JM; Zhang L; Xu J; Howard K; Lo S; Cass A; Perkovic V, 2017, 'A trial of extending hemodialysis hours and quality of life', Journal of the American Society of Nephrology, 28, pp. 1898 - 1911, http://dx.doi.org/10.1681/ASN.2015111225

Liyanage T; Ninomiya T; Perkovic V; Woodward M; Stirnadel-Farrant H; Matsushita K; Iseki K; Seong HL; Monaghan H; Jha V, 2017, 'Chronic kidney disease in Asia: Protocol for a collaborative overview', Nephrology, 22, pp. 456 - 462, http://dx.doi.org/10.1111/nep.12821

Jun M; James MT; Ma Z; Zhang J; Tonelli M; McAlister FA; Manns BJ; Ravani P; Quinn RR; Wiebe N; Perkovic V; Wilton SB; Winkelmayer WC; Hemmelgarn BR, 2017, 'Warfarin Initiation, Atrial Fibrillation, and Kidney Function: Comparative Effectiveness and Safety of Warfarin in Older Adults With Newly Diagnosed Atrial Fibrillation', American Journal of Kidney Diseases, 69, pp. 734 - 743, http://dx.doi.org/10.1053/j.ajkd.2016.10.018

Perkovic V; Levin A; Wheeler D; Koitka-Weber A; Mattheus M; George J; von Eynatten M; Wanner C, 2017, 'SO019EFFECTS OF EMPAGLIFLOZIN ON CARDIOVASCULAR OUTCOMES ACROSS KDIGO RISK CATEGORIES: RESULTS FROM THE EMPA-REG OUTCOME® TRIAL', Nephrology Dialysis Transplantation, 32, pp. iii12 - iii12, http://dx.doi.org/10.1093/ndt/gfx103

Wanner C; Levin A; Perkovic V; Koitka-Weber A; Mattheus M; von Eynatten M; Wheeler D, 2017, 'SP259EFFECTS OF EMPAGLIFLOZIN ON RENAL OUTCOMES ACROSS KDIGO RISK CATEGORIES: RESULTS FROM THE EMPA-REG OUTCOME® TRIAL', Nephrology Dialysis Transplantation, 32, pp. iii193 - iii194, http://dx.doi.org/10.1093/ndt/gfx145.sp259

Pena MJ; de Zeeuw D; Andress D; Brennan JJ; Correa-Rotter R; Coll B; Kohan DE; Makino H; Perkovic V; Remuzzi G; Tobe SW; Toto R; Parving HH; Sharma S; Corringham T; Sharma K; Heerspink HJL, 2017, 'The effects of atrasentan on urinary metabolites in patients with type 2 diabetes and nephropathy', Diabetes, Obesity and Metabolism, 19, pp. 749 - 753, http://dx.doi.org/10.1111/dom.12864

Heerspink HJL; Makino H; Andress D; Brennan JJ; Correa-Rotter R; Coll B; Davis JW; Idler K; Kohan DE; Liu M; Perkovic V; Remuzzi G; Tobe SW; Toto R; Parving HH; de Zeeuw D, 2017, 'Comparison of exposure response relationship of atrasentan between North American and Asian populations', Diabetes, Obesity and Metabolism, 19, pp. 545 - 552, http://dx.doi.org/10.1111/dom.12851

Neal B; Perkovic V; Matthews DR; Mahaffey KW; Fulcher G; Meininger G; Erondu N; Desai M; Shaw W; Vercruysse F; Yee J; Deng H; de Zeeuw D, 2017, 'Rationale, design and baseline characteristics of the CANagliflozin cardioVascular Assessment Study–Renal (CANVAS-R): A randomized, placebo-controlled trial', Diabetes, Obesity and Metabolism, 19, pp. 387 - 393, http://dx.doi.org/10.1111/dom.12829

Lo C; Jun M; Badve SV; Pilmore H; White SL; Hawley C; Cass A; Perkovic V; Zoungas S, 2017, 'Glucose-lowering agents for treating pre-existing and new-onset diabetes in kidney transplant recipients', Cochrane Database of Systematic Reviews, 2017, http://dx.doi.org/10.1002/14651858.CD009966.pub2

Heerspink HJL; Desai M; Jardine M; Balis D; Meininger G; Perkovic V, 2017, 'Canagliflozin slows progression of renal function decline independently of glycemic effects', Journal of the American Society of Nephrology, 28, pp. 368 - 375, http://dx.doi.org/10.1681/ASN.2016030278

Neuen BL; Chadban SJ; Demaio AR; Johnson DW; Perkovic V, 2017, 'Chronic kidney disease and the global NCDs agenda', BMJ Global Health, 2, http://dx.doi.org/10.1136/bmjgh-2017-000380

Su X; Xie X; Liu L; Lv J; Song F; Perkovic V; Zhang H, 2017, 'Comparative Effectiveness of 12 Treatment Strategies for Preventing Contrast-Induced Acute Kidney Injury: A Systematic Review and Bayesian Network Meta-analysis', American Journal of Kidney Diseases, 69, pp. 69 - 77, http://dx.doi.org/10.1053/j.ajkd.2016.07.033

Atkins ER; Hirakawa Y; Salam A; Woodward M; Cooper M; Hamet P; Harrap S; Lees K; Liu L; Mancia G; Marre M; Perkovic V; Poulter N; Williams B; Chalmers J; Rodgers A, 2017, 'Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: An analysis of the PROGRESS and ADVANCEtrials', Journal of Hypertension, 35, pp. 1318 - 1325, http://dx.doi.org/10.1097/HJH.0000000000001287

Perkovic V, 2016, 'Commentary', Annals of Internal Medicine, 165, pp. JC71, http://dx.doi.org/10.7326/ACPJC-2016-165-12-071

Perkovic V; Agarwal R; Fioretto P; Hemmelgarn BR; Levin A; Thomas MC; Wanner C; Kasiske BL; Wheeler DC; Groop PH; Bakris GL; Cooper ME; Chae DW; Davidson MH; de Boer IH; de Zeeuw D; Fornoni A; Gnudi L; Herzog CA; Hung AM; Jafar TH; Jardine M; Jha V; Ji L; Kahn SE; Langham RG; Lerma EV; Ma RCW; Makino H; Marre M; Mauer M; Metsärinne K; Nelson RG; Pecoits-Filho R; Pollock CA; Rajapurkar M; Rossing P; Rychlík I; Sharma K; Stanton RC; Tesař V; Tikkanen I; Tomson CRV; Toto RD; Tsukamoto Y; Tuttle KR; Wada T; Williams WW; Zhang H; Zoungas S, 2016, 'Management of patients with diabetes and CKD: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference', Kidney International, 90, pp. 1175 - 1183, http://dx.doi.org/10.1016/j.kint.2016.09.010

Olsen MH; Angell SY; Asma S; Boutouyrie P; Burger D; Chirinos JA; Damasceno A; Delles C; Gimenez-Roqueplo AP; Hering D; López-Jaramillo P; Martinez F; Perkovic V; Rietzschel ER; Schillaci G; Schutte AE; Scuteri A; Sharman JE; Wachtell K; Wang JG, 2016, 'A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension', The Lancet, 388, pp. 2665 - 2712, http://dx.doi.org/10.1016/S0140-6736(16)31134-5

Wong MG; Perkovic V, 2016, 'Knowing what we do not know: statin therapy in advanced chronic kidney disease', The Lancet Diabetes and Endocrinology, 4, pp. 801 - 803, http://dx.doi.org/10.1016/S2213-8587(16)30192-9

Quach K; Lvtvyn L; Baigent C; Bueti J; Garg AX; Hawley C; Haynes R; Manns B; Perkovic V; Rabbat CG; Wald R; Walsh M, 2016, 'The Safety and Efficacy of Mineralocorticoid Receptor Antagonists in Patients Who Require Dialysis: A Systematic Review and Meta-analysis', American Journal of Kidney Diseases, 68, pp. 591 - 598, http://dx.doi.org/10.1053/j.ajkd.2016.04.011

Badve SV; Palmer SC; Strippoli GFM; Roberts MA; Teixeira-Pinto A; Boudville N; Cass A; Hawley CM; Hiremath SS; Pascoe EM; Perkovic V; Whalley GA; Craig JC; Johnson DW, 2016, 'The Validity of Left Ventricular Mass as a Surrogate End Point for All-Cause and Cardiovascular Mortality Outcomes in People With CKD: A Systematic Review and Meta-analysis', American Journal of Kidney Diseases, 68, pp. 554 - 563, http://dx.doi.org/10.1053/j.ajkd.2016.03.418

Patel MR; Armstrong PW; Bhatt DL; Braunwald E; Camm AJ; Fox KAA; Harrington RA; Hiatt WR; James SK; Kirtane AJ; Leon MB; Lincoff AM; Mahaffey KW; Mauri L; Mehran R; Mehta SR; Montalescot G; Nicholls SJ; Perkovic V; Peterson ED; Pocock SJ; Roe MT; Sabatine MS; Sekeres M; Solomon SD; Steg G; Stone GW; Van De Werf F; Wallentin L; White HD; Gibson CM, 2016, 'Sharing data from cardiovascular clinical trials \- a proposal', New England Journal of Medicine, 375, pp. 407 - 409, http://dx.doi.org/10.1056/NEJMp1605260

Liyanage T; Ninomiya T; Wang A; Neal B; Jun M; Wong MG; Jardine M; Hillis GS; Perkovic V; Jun M; Wang Y, 2016, 'Effects of the mediterranean diet on cardiovascular outcomes-a systematic review and meta-analysis', PLoS ONE, 11, pp. e0159252, http://dx.doi.org/10.1371/journal.pone.0159252

Gabb GM; Mangoni A; Anderson CS; Cowley D; Dowden JS; Golledge J; Hankey GJ; Howes FS; Leckie L; Perkovic V; Schlaich M; Zwar NA; Medley TL; Arnolda L, 2016, 'Guideline for the diagnosis and management of hypertension in adults — 2016', Medical Journal of Australia, 205, pp. 85 - 89, http://dx.doi.org/10.5694/mja16.00526

Chan KE; Giugliano RP; Patel MR; Abramson S; Jardine M; Zhao S; Perkovic V; Maddux FW; Piccini JP, 2016, 'Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF', Journal of the American College of Cardiology, 67, pp. 2888 - 2899, http://dx.doi.org/10.1016/j.jacc.2016.02.082

Rodgers A; Perkovic V, 2016, 'A randomized trial of intensive versus standard blood-pressure control [10]', New England Journal of Medicine, 374, pp. 2295, http://dx.doi.org/10.1056/NEJMc1602668

Roberts MA; Pilmore HL; Ierino FL; Badve SV; Cass A; Garg AX; Isbel NM; Krum H; Pascoe EM; Perkovic V; Scaria A; Tonkin AM; Vergara LA; Hawley CM; Levin A; Hare D; Martin A; Wheeler DC; Fulcher G; Brown H; Colquhoun D; Korczyk D; Mather A; Wong A; Bisscheroux P; Gillies A; Garvey L; Tan KS; Lennan E; Pitkin M; Ahearn K; Carroll RP; Scott E; Cooper B; Pearse J; Snelling P; Burman J; Hand S; Pedagogos E; Karschimkus C; Pilmore A; Walker R; Ellis G; Marshall MR; Paul C; Johnson D; Helyar J; Morrish A; Paul-Brent PA; Reidlinger D; Zhang L, 2016, 'The β-Blocker to Lower Cardiovascular Dialysis Events (BLOCADE) feasibility study: A randomized controlled trial', American Journal of Kidney Diseases, 67, pp. 902 - 911, http://dx.doi.org/10.1053/j.ajkd.2015.10.029

Nigwekar SU; Kang A; Zoungas S; Cass A; Gallagher MP; Kulshrestha S; Navaneethan SD; Perkovic V; Strippoli GFM; Jardine MJ, 2016, 'Interventions for lowering plasma homocysteine levels in dialysis patients', Cochrane Database of Systematic Reviews, 2016, http://dx.doi.org/10.1002/14651858.CD004683.pub4

Wu JHY; Foote C; Blomster J; Toyama T; Perkovic V; Sundström J; Neal B, 2016, 'Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: A systematic review and meta-analysis', The Lancet Diabetes and Endocrinology, 4, pp. 411 - 419, http://dx.doi.org/10.1016/S2213-8587(16)00052-8

Wong MG; Perkovic V; Chalmers J; Woodward M; Li Q; Cooper ME; Hamet P; Harrap S; Heller S; Macmahon S; Mancia G; Marre M; Matthews D; Neal B; Poulter N; Rodgers A; Williams B; Zoungas S, 2016, 'Long-term benefits of intensive glucose Control for preventing end-stage kidney disease: ADVANCE-ON', Diabetes Care, 39, pp. 694 - 700, http://dx.doi.org/10.2337/dc15-2322

Schievink B; De Zeeuw D; Smink PA; Andress D; Brennan JJ; Coll B; Correa-Rotter R; Hou FF; Kohan D; Kitzman DW; Makino H; Parving HH; Perkovic V; Remuzzi G; Tobe S; Toto R; Hoekman J; Lambers Heerspink HJ, 2016, 'Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers', European Journal of Preventive Cardiology, 23, pp. 758 - 768, http://dx.doi.org/10.1177/2047487315598709

Xie X; Liu Y; Perkovic V; Li X; Ninomiya T; Hou W; Zhao N; Liu L; Lv J; Zhang H; Wang H, 2016, 'Renin-Angiotensin System Inhibitors and Kidney and Cardiovascular Outcomes in Patients with CKD: A Bayesian Network Meta-analysis of Randomized Clinical Trials', American Journal of Kidney Diseases, 67, pp. 728 - 741, http://dx.doi.org/10.1053/j.ajkd.2015.10.011

Wang Y; Ivany JN; Perkovic V; Gallagher MP; Woodward M; Jardine MJ, 2016, 'Anticoagulants and antiplatelet agents for preventing central venous haemodialysis catheter malfunction in patients with end-stage kidney disease', Cochrane Database of Systematic Reviews, 2016, http://dx.doi.org/10.1002/14651858.CD009631.pub2

Gallagher M; Wong MG; Perkovic V, 2016, 'ALTITUDE: Defining a ceiling for blockade of the renin-angiotensin system?', The Lancet Diabetes and Endocrinology, 4, pp. 289 - 290, http://dx.doi.org/10.1016/S2213-8587(15)00518-5

Knight J; Perkovic V, 2016, 'The Affordable Dialysis Prize steams ahead', The Lancet, 387, pp. 1040, http://dx.doi.org/10.1016/S0140-6736(16)00657-7

Dal-Ré R; Jha V; Lv J; Chaudhury RR; Wang Y; Perkovic V, 2016, 'International trials in middle-income countries: different local scenarios require different ethical approaches', Journal of the Royal Society of Medicine, 109, pp. 47 - 51, http://dx.doi.org/10.1177/0141076815608854

Xie X; Atkins E; Lv J; Bennett A; Neal B; Ninomiya T; Woodward M; MacMahon S; Turnbull F; Hillis GS; Chalmers J; Mant J; Salam A; Rahimi K; Perkovic V; Rodgers A, 2016, 'Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: Updated systematic review and meta-analysis', The Lancet, 387, pp. 435 - 443, http://dx.doi.org/10.1016/S0140-6736(15)00805-3

Zhang L; Coombes J; Pascoe EM; Badve SV; Dalziel K; Cass A; Clarke P; Ferrari P; McDonald SP; Morrish AT; Pedagogos E; Perkovic V; Reidlinger D; Scaria A; Walker R; Vergara LA; Hawley CM; Johnson DW, 2016, 'The effect of pentoxifylline on oxidative stress in chronic kidney disease patients with erythropoiesis-stimulating agent hyporesponsiveness: Sub-study of the HERO trial', Redox Report, 21, pp. 14 - 23, http://dx.doi.org/10.1179/1351000215Y.0000000022

Sukkar L; Hong D; Wong MG; Badve SV; Rogers K; Perkovic V; Walsh M; Yu X; Hillis GS; Gallagher M; Jardine M, 2016, 'Effects of ischaemic conditioning on major clinical outcomes in people undergoing invasive procedures: Systematic review and meta-analysis', BMJ (Online), 355, http://dx.doi.org/10.1136/bmj.i5599

Fulcher G; Matthews DR; Perkovic V; de Zeeuw D; Mahaffey KW; Mathieu C; Woo V; Wysham C; Capuano G; Desai M; Shaw W; Vercruysse F; Meininger G; Neal B; Home P; Anderson J; Campbell I; Lachin J; Scharfstein D; Solomon S; Uzzo R; Amerena J; Chow C; Figtree G; French G; Hillis J; Jenkins B; Lindley R; McGrath B; Street A; Watson J, 2016, 'Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes', Diabetes, Obesity and Metabolism, 18, pp. 82 - 91, http://dx.doi.org/10.1111/dom.12589

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