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Researcher

Professor Jake Baum

My Expertise

I am an expert in cell biology and infectious disease, having spent more than 20 years working on the parasite that causes malaria. I have pioneered fundamental discovery research through to applied research on the malaria parasite, with major career contributions to drug discovery, diagnostics and vaccines.

My core areas of expertise include:

  • The rational design and testing of malaria vaccines
  • Imaging-based high throughput drug discovery screens
  • Development of point-of-care infection diagnostics
  • Interdisciplinary research at the interface between fields including cell biology with physics, chemistry, structural biology or mathematics (including machine learning)
  • Industry-academic partnerships
  • Evolutionary biology and host-pathogen coevolution

Keywords

Fields of Research (FoR)

Biochemistry and cell biology, Infectious diseases, Medical parasitology, Cellular immunology, Medical biotechnology diagnostics (incl. biosensors), Other biomedical and clinical sciences not elsewhere classified

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Biography

I am a parasitologist, cell biologist and medical science innovator. Following Bachelors’ and Masters’ degrees at Oxford, and PhD in London (LSHTM, 2002) I moved to the Walter + Eliza Hall Institute in Melbourne, Australia to work on the molecular and cellular biology of the malaria parasite. I started my own independent lab at the WEHI in 2010 (www.baumlab.com). In 2013, I returned to the UK to Imperial College London, and was later...view more

I am a parasitologist, cell biologist and medical science innovator. Following Bachelors’ and Masters’ degrees at Oxford, and PhD in London (LSHTM, 2002) I moved to the Walter + Eliza Hall Institute in Melbourne, Australia to work on the molecular and cellular biology of the malaria parasite. I started my own independent lab at the WEHI in 2010 (www.baumlab.com). In 2013, I returned to the UK to Imperial College London, and was later appointed Professor of Cell Biology and Infectious Diseases (2017). In 2020 I helped found the Imperial College Institute of Infection, a new Institute charged with representing the entire interdisciplinary research portfolio of infection research across the University. In 2022, I was recruited back to Australia to take up a tenured Professorship and position as Head of School of Medical Sciences at UNSW, Sydney. My lab (www.baumlab.com) has had a diverse range of interests, across cell biology, drug discovery, novel diagnostics, and vaccine technologies, often working together with industry partnerships. I have mentored to completion 13 PhD students, 20+ postdocs and supported >100 researchers through my lab. 5 former lab members are now independent PIs, 1 is a Journal Editor and 2 have started their own spin-out companies. Throughout my career I’ve been passionate about supporting early career researchers advance their careers in science.

Career highlights include:


My Grants

Current funding for the Baum lab comes from:

  • The Wellcome Trust (UK)
  • The Bill & Melinda Gates Foundation (US)
  • NIH (US)
  • The RoseTrees Trust (UK)

My Qualifications

  • Ph.D. in Infectious & Tropical Diseases. Co-evolution of Genetic Diversity in Malaria and Humans. London School of Hygiene & Tropical Medicine (University of London), UK (1999-2002; awarded 31-08-2002).
  • M.Sc. Human Biology. University of Oxford, Magdalen College, UK (1997-1998).
  • B.A. Hons (M.A. Oxon). Biological Sciences. University of Oxford, St. Catherine’s College, UK (1993-1996).

My Awards

  • 2020 Imperial College London President's Awards for Excellence in Societal Engagement.
  • 2017, 2018 and 2019 Nomination Best Teaching Award. 2018 Nominated and Short-listed for Best Feedback Award by Imperial College Union Student Academic Choice Awards.
  • 2013 Merck Millipore Research Medal from the Australian Society for Biochemistry and Molecular Biology (ASBMB).
  • 2011 Walter + Eliza Hall Institute Burnet Prize.
  • 2009 Victorian/Tasmania Young Tall Poppy Science Award Winner.
  • 2007 ARC/NHMRC Australian Parasitological Society Early Career Researcher award

My Research Activities

  • Development of novel, multi-epitope malaria vaccines
  • Dissection-independent isolation of malaria parasite sporozoites
  • Cell free protein translation by in vitro translation (IVT) using Plasmodium cell lysate
  • Digital point-of-care diagnostics for malaria and other infectious diseases
  • High throughput drug screening for antimalarials
  • Cell biology - with a core focus on malaria parasite cell motility and general cell biology

My Research Supervision


Supervision keywords

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Location

Level 2 West
Wallace Wurth Building (C27)
UNSW, Kensington Campus

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Contact

+61-2-9065 7439