By Assistant Professor Paul Ekert

Journal articles

Marsden VS; Ekert PG; Van Delft M; Vaux DL; Adams JM; Strasser A, 2004, 'Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9', Journal of Cell Biology, 165, pp. 775 - 780, http://dx.doi.org/10.1083/jcb.200312030

Knight MJ; Riffkin CD; Ekert PG; Ashley DM; Hawkins CJ, 2004, 'Caspase-8 Levels Affect Necessity for Mitochondrial Amplification in Death Ligand-Induced Glioma Cell Apoptosis', Molecular Carcinogenesis, 39, pp. 173 - 182, http://dx.doi.org/10.1002/mc.20011

Silke J; Kratina T; Ekert PG; Pakusch M; Vaux DL, 2004, 'Unlike Diablo/smac, Grim Promotes Global Ubiquitination and Specific Degradation of X Chromosome-linked Inhibitor of Apoptosis (XIAP) and Neither Cause Apoptosis', Journal of Biological Chemistry, 279, pp. 4313 - 4321, http://dx.doi.org/10.1074/jbc.M305661200

Hennel SJ; Ekert PG; Volpe JJ; Inder TE, 2003, 'Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti', Pediatric Neurology, 29, pp. 148 - 150, http://dx.doi.org/10.1016/S0887-8994(03)00150-4

Read SH; Baliga BC; Ekert PG; Vaux DL; Kumar S, 2002, 'A novel Apaf-1-independent putative caspase-2 activation complex', Journal of Cell Biology, 159, pp. 739 - 745, http://dx.doi.org/10.1083/jcb.200209004

Jabbour AM; Ekert PG; Coulson EJ; Knight MJ; Ashley DM; Hawkins CJ, 2002, 'The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects againts apoptosis', Cell Death and Differentiation, 9, pp. 1311 - 1320, http://dx.doi.org/10.1038/sj.cdd.4401135

Marsden VS; O’Connor L; O’Reilly LA; Silke J; Metcalf D; Ekert PG; Huang DCS; Cecconi F; Kuida K; Tomaselli KJ; Roy S; Nicholson DW; Vaux DL; Bouillet P; Adams JM; Strasser A, 2002, 'Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome', Nature, 419, pp. 634 - 637, http://dx.doi.org/10.1038/nature01101

Silke J; Hawkins CJ; Ekert PG; Chew J; Day CL; Pakusch M; Verhagen AM; Vaux DL, 2002, 'The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites', Journal of Cell Biology, 157, pp. 115 - 124, http://dx.doi.org/10.1083/jcb.200108085

Verhagen AM; Silke J; Ekert PG; Pakusch M; Kaufmann H; Connolly LM; Day CL; Tikoo A; Burke R; Wrobel C; Moritz RL; Simpson RJ; Vaux DL, 2002, 'HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins', Journal of Biological Chemistry, 277, pp. 445 - 454, http://dx.doi.org/10.1074/jbc.M109891200

O’Reilly LA; Ekert P; Harvey N; Marsden V; Cullen L; Vaux DL; Hacker G; Magnusson C; Pakusch M; Cecconi F; Kuida K; Strasser A; Huang DCS; Kumar S, 2002, 'Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9', Cell Death and Differentiation, 9, pp. 832 - 841, http://dx.doi.org/10.1038/sj.cdd.4401033

Hawkins CJ; Silke J; Verhagen AM; Foster R; Ekert PG; Ashley DM, 2001, 'Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism', Apoptosis, 6, pp. 331 - 338, http://dx.doi.org/10.1023/A:1011329917895

Ekert PG; Silke J, 2001, 'Till death do us part', Cell Death and Differentiation, 8, pp. 662 - 664, http://dx.doi.org/10.1038/sj.cdd.4400895

Silke J; Ekert PG; Day CL; Hawkins CJ; Baca M; Chew J; Pakusch M; Verhagen AM; Vaux DL, 2001, 'Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP', EMBO Journal, 20, pp. 3114 - 3123, http://dx.doi.org/10.1093/emboj/20.12.3114

Ekert PG; Silke J; Hawkins CJ; Verhagen AM; Vaux DL, 2001, 'DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9', Journal of Cell Biology, 153, pp. 483 - 490, http://dx.doi.org/10.1083/jcb.152.3.483

Mills JF; Dargaville PA; Coleman LT; Rosenfeld JV; Ekert PG, 2001, 'Upper cervical spinal cord injury in neonates: The use of magnetic resonance imaging', Journal of Pediatrics, 138, pp. 105 - 108, http://dx.doi.org/10.1067/mpd.2001.109195

Silke J; Verhagen AM; Ekert PG; Vaux DL, 2000, 'Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and Hid? [3]', Cell Death and Differentiation, 7, pp. 1275, http://dx.doi.org/10.1038/sj.cdd.4400790

Verhagen AM; Ekert PG; Pakusch M; Silke J; Connolly LM; Reid GE; Moritz RL; Simpson RJ; Vaux DL, 2000, 'Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins', Cell, 102, pp. 43 - 53, http://dx.doi.org/10.1016/S0092-8674(00)00009-X

Ekert PA; Bucher DJ, 1999, 'Winter Use of Large-leafed Privet Ligustrum lucidum (Family: Oleaceae) by Birds in Suburban Lismore, New South Wales', Proceedings of the Linnean Society of New South Wales, 1999, pp. 29 - 38

Soilu-Hänninen M; Ekert P; Bucci T; Syroid D; Bartlett PF; Kilpatrick TJ, 1999, 'Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway', Journal of Neuroscience, 19, pp. 4828 - 4838, http://dx.doi.org/10.1523/jneurosci.19-12-04828.1999

Ekert PG; Silke J; Vaux DL, 1999, 'Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: Optimal caspase substrates are not necessarily optimal inhibitors', EMBO Journal, 18, pp. 330 - 338, http://dx.doi.org/10.1093/emboj/18.2.330

Ekert PG; Silke J; Vaux DL, 1999, 'Caspase inhibitors', Cell Death and Differentiation, 6, pp. 1081 - 1086, http://dx.doi.org/10.1038/sj.cdd.4400594

Hawkins CJ; Ekert PG; Uren AG; Holmgreen SP; Vaux DL, 1998, 'Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells', Cell Death and Differentiation, 5, pp. 569 - 576, http://dx.doi.org/10.1038/sj.cdd.4400389

Ekert P; Mougenot JF; De Lagausie P; Gerardin M; Le Bourgeois M; Munck A; Aigrain Y; Navarro J, 1998, 'Intussusception and appendiceal mucocele in a child with cystic fibrosis', Archives de Pediatrie, 5, pp. 400 - 403, http://dx.doi.org/10.1016/S0929-693X(98)80027-4

Raju NV; Ekert P; Kumar A; Perlman M, 1998, 'Base Deficit (BD) in Babies with Post-asphyxial Hypoxic Ischemic Encephalopathy (PA-HIE) and relationship to Outcome 1107', Pediatric Research, 43, pp. 190 - 190, http://dx.doi.org/10.1203/00006450-199804001-01128

Ekert PG; Huang D; Vaux DL, 1998, 'Cloning and testing new genes to block specific caspase family members.† 998', Pediatric Research, 43, pp. 172 - 172, http://dx.doi.org/10.1203/00006450-199804001-01019

Ekert P; Perlman M; Steinlin M; Hao Y, 1998, 'Predicting the Outcome of Postasphyxial Hypoxic-Ischemic Encephalopathy Within 4 Hours of Birth', Obstetrical & Gynecological Survey, 53, pp. 409 - 410, http://dx.doi.org/10.1097/00006254-199807000-00011

Barnett CP; Perlman M; Ekert PG, 1997, 'Clinicopathological correlations in postasphyxial organ damage: A donor organ perspective', Pediatrics, 99, pp. 797 - 799, http://dx.doi.org/10.1542/peds.99.6.797

Ekert P; MacLusky N; Luo XP; Lehotay DC; Smith B; Post M; Tanswell AK, 1997, 'Dexamethasone prevents apoptosis in a neonatal rat model of hypoxic-ischemic encephalopathy (HIE) by a reactive oxygen species-independent mechanism', Brain Research, 747, pp. 9 - 17, http://dx.doi.org/10.1016/S0006-8993(96)01201-2

Vaux DL; Hawkins CJ; Uren AG; Ekert PG, 1997, 'Motor neurone disease and the life of motor neurones', MEDICAL JOURNAL OF AUSTRALIA, 166, pp. 109 - 109, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WE11200025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ekert PG; Vaux DL, 1997, 'Apoptosis and the immune system', British Medical Bulletin, 53, pp. 591 - 603, http://dx.doi.org/10.1093/oxfordjournals.bmb.a011632

Ekert PG; Vaux DL, 1997, 'Apoptosis, haemopoiesis and leukaemogenesis', Bailliere's Clinical Haematology, 10, pp. 561 - 576, http://dx.doi.org/10.1016/S0950-3536(97)80026-1

Ekert PG; Taylor MJ; Keenan NK; Boulton JE; Whyte HE, 1997, 'Early Somatosensory Evoked Potentials in Preterm Infants: Their Prognostic Utility', Neonatology, 71, pp. 83 - 91, http://dx.doi.org/10.1159/000244401

Ekert P; Perlman M; Steinlin M; Hao Y, 1997, 'Predicting the outcome of postasphyxial hypoxic-ischemic encephalopathy within 4 hours of birth', Journal of Pediatrics, 131, pp. 613 - 617, http://dx.doi.org/10.1016/S0022-3476(97)70072-6

Ekert PG; Keenan NK; Whyte HE; Boulton J; Taylor MJ, 1997, 'Visual evoked potentials for prediction of neurodevelopmental outcome in preterm infants', Neonatology, 71, pp. 148 - 155, http://dx.doi.org/10.1159/000244410

Taylor MJ; Boor R; Ekert PG, 1996, 'Preterm maturation of the somatosensory evoked potential', Electroencephalography and Clinical Neurophysiology - Evoked Potentials, 100, pp. 448 - 452, http://dx.doi.org/10.1016/0168-5597(96)95218-1

Ekert PG; MacLusky N; Becker L; Post M; Tanswell AK, 1996, 'DEXAMETHASONE NEUROPROTECTION IS ASSOCIATED WITH PRESERVED EXPRESSION OF BCL-2 AND SUPPRESSION OF GLIAL FIBRILLARY ACID PROTEIN (GFAP). ▴ 1226', Pediatric Research, 39, pp. 207 - 207, http://dx.doi.org/10.1203/00006450-199604001-01248

Ekert PG; MacLusky N; Ping X; Lahotay D; Post M; Tanswell AK, 1996, 'DEXAMETHASONE PREVENTS APOPTOSIS IN A RAT MODEL OF NEONATAL HYPOXIC-ISCHEMIC ENCEPHALOPATHY (HIE) BY A FREE RADICAL INDEPENDENT MECHANISM. ▴ 1227', Pediatric Research, 39, pp. 207 - 207, http://dx.doi.org/10.1203/00006450-199604001-01249

Barnett CP; Ekert PG; Perlman M, 1996, 'SERUM TRANSAMINASE MEASUREMENTS IN POST-ASPHYXIAL (PA) HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE). 1743', Pediatric Research, 39, pp. 293 - 293, http://dx.doi.org/10.1203/00006450-199604001-01767

Kalidasan V; Ekert P; Beasley SW, 1994, 'Associations of urachal abnormalities: Does patency of the urachus occur because of distal urinary tract obstruction?', Pediatric Surgery International, 9, pp. 381 - 382, http://dx.doi.org/10.1007/BF01686007

Steinlin M; Ekert PG; Blaser S; Otsubo H; Taylor MJ; Whyte HE; Perlman M, 1994, 'Prediction of severe adverse outcome after moderate or severe birth asphyxia', Pediatric Neurology, 11, pp. 81 - 81, http://dx.doi.org/10.1016/0887-8994(94)90146-5

Ekert P; Metreau JM; Zafrani ES; Fabre M; Buffet C; Etienne JP; Dhumeaux D, 1991, 'Hepatic cholesterol ester storage disease: Two new cases diagnosed in adults', Gastroenterologie Clinique et Biologique, 15, pp. 441 - 444

GARGOT D; CADRANEL JF; EKERT P; NOVELLO P; ZYLBERBERG H; BENHAMOU Y, 1990, 'CHRONIC-PANCREATITIS', GAZETTE MEDICALE, 97, pp. 41 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1990EA70500008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dewan PA; Ekert P; Keogh EJ; Solomon JR, 1989, 'Epithelial bridging on burn patients following primary excision and grafting', Burns, 15, pp. 129 - 131, http://dx.doi.org/10.1016/0305-4179(89)90145-9

EKERT P; TIBBALLS J; GORMAN D, 1988, 'Three patients with carbon monoxide poisoning treated with hyperbaric oxygen therapy', Journal of Paediatrics and Child Health, 24, pp. 194 - 196, http://dx.doi.org/10.1111/j.1440-1754.1988.tb00324.x

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