Select Publications
Journal articles
, 2021, 'The DNA binding properties of 9-aminoacridine carboxamide Pt complexes', Bioorganic and Medicinal Chemistry, 40, http://dx.doi.org/10.1016/j.bmc.2021.116191
, 2017, 'Analysis of Alternative Strategies for the Teaching of Difficult Threshold Concepts in Large Undergraduate Medicine and Science Classes', Medical Science Educator, 27, pp. 673 - 684, http://dx.doi.org/10.1007/s40670-017-0453-x
, 2014, 'Enhanced DNA repair of bleomycin-induced 3'-phosphoglycolate termini at the transcription start sites of actively transcribed genes in human cells', Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 769, pp. 93 - 99, http://dx.doi.org/10.1016/j.mrfmmm.2014.06.006
, 2014, 'Characterising the atypical 5′-CG DNA sequence specificity of 9-aminoacridine carboxamide Pt complexes', Journal of Biological Inorganic Chemistry, 19, pp. 997 - 1007, http://dx.doi.org/10.1007/s00775-014-1144-3
, 2014, 'The anti-tumor drug bleomycin preferentially cleaves at the transcription start sites of actively transcribed genes in human cells', Cellular and Molecular Life Sciences, 71, pp. 1505 - 1512, http://dx.doi.org/10.1007/s00018-013-1456-4
, 2014, 'The potential of acridine carboxamide Pt complexes as anti-cancer agents: A review', Anti-Cancer Agents in Medicinal Chemistry, 14, pp. 695 - 705, http://dx.doi.org/10.2174/18715206113136660361
, 2013, 'The interaction of cisplatin with a human telomeric DNA sequence containing seventeen tandem repeats', Bioorganic and Medicinal Chemistry Letters, 23, pp. 1041 - 1045, http://dx.doi.org/10.1016/j.bmcl.2012.12.021
, 2012, 'Controlling the size of lipid droplets: Lipid and protein factors', Current Opinion in Cell Biology, 24, pp. 509 - 516, http://dx.doi.org/10.1016/j.ceb.2012.05.012
, 2012, 'Gene expression profiling of the cancer chemotherapeutic agent, Cisplatin, compared with its ineffective isomer, Transplatin.', Journal of Computer Science and Systems Biology, 5, pp. 37, http://dx.doi.org/10.4172/0974-7230.S1.02
, 2010, 'Cholesterol as an evolutionary response to living with oxygen.', Evolution, 64, pp. 2179 - 2183
, 2009, 'Special relationship between sterols and oxygen: Were sterols an adaptation to aerobic life?', Free Radical Biology and Medicine, 47, pp. 880 - 889
, 2008, 'The anti-tumour agent, Cisplatin, and its clinically ineffective isomer, Transplatin, produce unique gene expression profiles in human cells', Cancer Informatics, 6, pp. 315 - 355
, 2002, 'The interaction of cisplatin and analogues with DNA in reconstituted chromatin', Biochimica et Biophysica Acta - Gene Structure and Expression, 1579, pp. 142 - 152, http://dx.doi.org/10.1016/S0167-4781(02)00535-3
, 2002, 'Cisplatin preferentially targets the linker region of the nucleosome', Biochim Biophys ACTA, 1579, pp. 142 - 152
Conference Papers
, 2009, 'The Unique Gene Expression Profile of the Anti-tumour Agent, Cisplatin, Compared with its Clinically Ineffective Isomer, Transplatin.', in Proceedings of the 2nd International Conference on Biomedical and Pharmaceutical Engineering, IEEE, Singapore, presented at
, 2002, 'Investigating the effect of cisplatin on human gene expression using cDNA microarrays', in Takayama K (ed.), School of Biotechnology and Biomolecular Sciences 1st Annual Symposium, Sydney, presented at
, 2002, 'The Interaction of cisplatin with DNA in reconstituted chromatin', in Genome Conference 2001: 22nd Annual Conference on the Organisation and Expression of the Genome, Lorne, Victoria, pp. 44 - 44, presented at
, 2002, 'Gene expression profiling of human tumour cells using cDNA microarrays: a model test system for anti-tumour drug development', in 2nd Australian Microarray Meeting, Sth Stradbroke Island, Australia, presented at
, 2002, 'The interaction of anti-tumour agents with nucleosomal core DNA in reconstituted chromatin', in ComBio Conference, Sydney, presented at
Theses / Dissertations
, 2006, Investigating the mechanism of action of the chemotherapeutic agent, cisplatin: drug-DNA interactions in reconstituted chromatin and human gene expression profiling.