Select Publications

Journal articles

Gadde S; Kleynhans A; Holien JK; Bhadbhade M; Nguyen PLD; Mittra R; Yu TT; Carter DR; Parker MW; Marshall GM; Cheung BB; Kumar N, 2023, 'Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma', Bioorganic Chemistry, 136,

Massudi H; Luo JS; Holien JK; Gadde S; Krishan S; Herath M; Koach J; Stevenson BW; Gorman MA; Venkat P; Mayoh C; Luo XQ; Parker MW; Cheung BB; Marshall GM, 2023, 'Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface', Cancers, 15, pp. 1822 - 1822,

Yuan X; Seneviratne JA; Du S; Xu Y; Chen Y; Jin Q; Jin X; Balachandran A; Huang S; Xu Y; Zhai Y; Lu L; Tang M; Dong Y; Cheung BB; Marshall GM; Shi W; Carter DR; Zhang C, 2022, 'Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory', Cell Reports, 41,

Xiao L; Karsa M; Ronca E; Bongers A; Kosciolek A; El-Ayoubi A; Revalde JL; Seneviratne JA; Cheung BB; Cheung LC; Kotecha RS; Newbold A; Bjelosevic S; Arndt GM; Lock RB; Johnstone RW; Gudkov AV; Gurova KV; Haber M; Norris MD; Henderson MJ; Somers K, 2022, 'The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression', Frontiers in Oncology, 12,

Seneviratne JA; Carter DR; Mittra R; Gifford A; Kim PY; Luo JS; Mayoh C; Salib A; Rahmanto AS; Murray J; Cheng NC; Nagy Z; Wang Q; Kleynhans A; Tan O; Sutton SK; Xue C; Chung SA; Zhang Y; Sun C; Zhang L; Haber M; Norris MD; Fletcher JI; Liu T; Dilda PJ; Hogg PJ; Cheung BB; Marshall GM, 2022, 'Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma', International Journal of Cancer,

Nagy Z; Seneviratne JA; Kanikevich M; Chang W; Mayoh C; Venkat P; Du Y; Jiang C; Salib A; Koach J; Carter DR; Mittra R; Liu T; Parker MW; Cheung BB; Marshall GM, 2021, 'An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability', Nature Communications, 12,

Van Thillo Q; De Bie J; Seneviratne JA; Demeyer S; Omari S; Balachandran A; Zhai V; Tam WL; Sweron B; Geerdens E; Gielen O; Provost S; Segers H; Boeckx N; Marshall GM; Cheung BB; Isobe K; Kato I; Takita J; Amos TG; Deveson IW; McCalmont H; Lock RB; Oxley EP; Garwood MM; Dickins RA; Uyttebroeck A; Carter DR; Cools J; de Bock CE, 2021, 'Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia', Nature Communications, 12, pp. 4164,

De Wyn J; Zimmerman MW; Weichert‐leahey N; Nunes C; Cheung BB; Abraham BJ; Beckers A; Volders PJ; Decaesteker B; Carter DR; Look AT; De Preter K; Van Loocke W; Marshall GM; Durbin AD; Speleman F; Durinck K, 2021, 'Meis2 is an adrenergic core regulatory transcription factor involved in early initiation of th‐mycn‐driven neuroblastoma formation', Cancers, 13,

Bingul M; Arndt GM; Marshall GM; Black DS; Cheung BB; Kumar N, 2021, 'Synthesis and characterisation of novel tricyclic and tetracyclic furoindoles: Biological evaluation as SAHA enhancer against neuroblastoma and breast cancer cells', Molecules, 26,

Cheung BB; Kleynhans A; Mittra R; Kim PY; Holien JK; Nagy Z; Ciampa OC; Seneviratne JA; Mayoh C; Raipuria M; Gadde S; Massudi H; Wong IPL; Tan O; Gong A; Suryano A; Diakiw SM; Liu B; Arndt GM; Liu T; Kumar N; Sangfelt O; Zhu S; Norris MD; Haber M; Carter DR; Parker MW; Marshall GM, 2021, 'A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma', Oncogene, 40, pp. 2367 - 2381,

Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, 27, pp. 1438 - 1451,

Gadde S; Leung YC; Bhadbade M; Cheung BB; Black DSC; Kumar N, 2020, 'Synthesis of a Novel Library of 1-Substituted Pyrido[1,2- a ]benzimidazoles', Australian Journal of Chemistry, 73, pp. 1208 - 1218,

Nagy Z; Cheung BB; Tsang W; Tan O; Herath M; Ciampa OC; Shadma F; Carter DR; Marshall GM, 2020, 'Withaferin A activates TRIM16 for its anti-cancer activity in melanoma', Scientific Reports, 10,

Stevenson BW; Gorman MA; Koach J; Cheung BB; Marshall GM; Parker MW; Holien JK, 2020, 'A structural view of PA2G4 isoforms with opposing functions in cancer', Journal of Biological Chemistry, 295, pp. 16100 - 16112,

Tee AE; Ciampa OC; Wong M; Fletcher JI; Kamili A; Chen J; Ho N; Sun Y; Carter DR; Cheung BB; Marshall GM; Liu PY; Liu T, 2020, 'Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma', International Journal of Cancer, 147, pp. 1928 - 1938,

Ni J; Cheung BB; Beretov J; Duan W; Bucci J; Malouf D; Graham P; Li Y, 2020, 'CD44 variant 6 is associated with prostate cancer growth and chemo-/radiotherapy response in vivo', Experimental Cell Research, 388, pp. 111850 - 111850,

Bingul M; Arndt GM; Marshall GM; Cheung BB; Kumar N; Black DSC, 2020, 'Synthesis, characterization and biological evaluation of novel dihydropyranoindoles improving the anticancer effects of HDAC inhibitors', Molecules, 25,

Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, 10, pp. 3319,

Liu PY; Tee AE; Milazzo G; Hannan KM; Maag J; Mondal S; Atmadibrata B; Bartonicek N; Peng H; Ho N; Mayoh C; Ciaccio R; Sun Y; Henderson MJ; Gao J; Everaert C; Hulme AJ; Wong M; Lan Q; Cheung BB; Shi L; Wang JY; Simon T; Fischer M; Zhang XD; Marshall GM; Norris MD; Haber M; Vandesompele J; Li J; Mestdagh P; Hannan RD; Dinger ME; Perini G; Liu T, 2019, 'The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35', Nature Communications, 10, pp. 5026,

Koach J; Holien JK; Massudi H; Carter DR; Ciampa OC; Herath M; Lim T; Seneviratne JA; Milazzo G; Murray JE; McCarroll JA; Liu B; Mayoh C; Keenan B; Stevenson BW; Gorman MA; Bell JL; Doughty L; Hüttelmaier S; Oberthuer A; Fischer M; Gifford AJ; Liu T; Zhang X; Zhu S; Gustafson WC; Haber M; Norris MD; Fletcher JI; Perini G; Parker MW; Cheung BB; Marshall GM, 2019, 'Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface', Cancer Research, 79, pp. 5652 - 5667,

Holien JK; Parker MW; Cheung B; Marshall G, 2019, 'Drugging the Undruggable: Inhibiting MYCN Signalling', The 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, 22, pp. 98 - 98,

Sutton SK; Cheung BB; Massudi H; Tan O; Koach J; Mayoh C; Carter DR; Marshall GM, 2019, 'Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis', Journal of Cancer Research and Clinical Oncology, 145, pp. 2241 - 2250,

Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, 11,

Hu X; Zheng W; Zhu Q; Gu L; Du Y; Han Z; Zhang X; Carter DR; Cheung BB; Qiu A; Jiang C, 2019, 'Increase in DNA damage by MYCN knockdown through regulating nucleosome organization and chromatin state in neuroblastoma', Frontiers in Genetics, 10,

Ooi CY; Carter DR; Liu B; Mayoh C; Beckers A; Lalwani A; Nagy Z; De Brouwer S; Decaesteker B; Hung TT; Norris MD; Haber M; Liu T; De Preter K; Speleman F; Cheung BB; Marshall GM, 2018, 'Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN', Cancer Research, 78, pp. 3122 - 3134,

Tang Y; Cheung BB; Atmadibrata B; Marshall GM; Dinger ME; Liu PY; Liu T, 2017, 'The regulatory role of long noncoding RNAs in cancer', Cancer Letters, 391, pp. 12 - 19,

Sutton SK; Carter DR; Kim P; Tan O; Arndt GM; Zhang XD; Baell J; Noll BD; Wang S; Kumar N; McArthur GA; Cheung BB; Marshall GM, 2016, 'A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner', Oncotarget, 7, pp. 52166 - 52178,

Bingul M; Tan O; Gardner CR; Sutton SK; Arndt GM; Marshall GM; Cheung BB; Kumar N; Black DSC, 2016, 'Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety', Molecules, 21,

Carter DR; Sutton SK; Pajic M; Murray J; Sekyere EO; Fletcher J; Beckers A; De Preter K; Speleman F; George RE; Haber M; Norris MD; Cheung BB; Marshall GM, 2016, 'Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis', Molecular Oncology, 10, pp. 866 - 878,

Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, 374, pp. 315 - 323,

Fabian J; Opitz D; Althoff K; Lodrini M; Hero B; Volland R; Beckers A; Preter KD; Decock A; Patil N; Abba M; Kopp-Schneider A; Astrahantseff K; Wünschel J; Pfeil S; Ercu M; Künkele A; Hu J; Thole T; Schweizer L; Mechtersheimer G; Carter D; Cheung BB; Popanda O; Deimling AV; Koster J; Versteeg R; Schwab M; Marshall GM; Speleman F; Erb U; Zoeller M; Allgayer H; Simon T; Fischer M; Kulozik AE; Eggert A; Witt O; Schulte JH; Deubzer HE, 2016, 'MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma', Oncotarget, 7, pp. 66344 - 66359,

Xue C; Yu DMT; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Valli E; Russell AJ; London WB; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4', Oncotarget, 7, pp. 54937 - 54951,

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, 7, pp. 79217 - 79232,

Tee AE; Liu B; Song R; Li J; Pasquier E; Cheung BB; Jiang C; Marshall GM; Haber M; Norris MD; Fletcher JI; Dinger ME; Liu T, 2016, 'The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression', Oncotarget, 7, pp. 8663 - 8675,

Koach J; Murray JE; McCarroll J; Milazzo G; Perini G; Haber M; Norris MD; Fletcher JI; Cheung BB; Marshall GM, 2016, 'Proffered Paper: Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma', European Journal of Cancer, 61, pp. S7 - S7,

Cheung BB, 2015, 'Combination therapies improve the anticancer activities of retinoids in neuroblastoma', World Journal of Clinical Oncology, 6, pp. 212 - 215,

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, 7,

Beckers A; Van Peer G; Carter DR; Gartlgruber M; Herrmann C; Agarwal S; Helsmoortel HH; Althoff K; Molenaar JJ; Cheung BB; Schulte JH; Benoit Y; Shohet JM; Westermann F; Marshall GM; Vandesompele J; De Preter K; Speleman F, 2015, 'MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma', Cancer Letters, 366, pp. 123 - 132,

Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, 9, pp. 1484 - 1500,

Lambertz I; Kumps C; Claeys S; Lindner S; Beckers A; Janssens E; Carter DR; Cazes A; Cheung BB; De Mariano M; De Bondt A; De Brouwer S; Delattre O; Gibbons J; Janoueix-Lerosey I; Laureys G; Liang C; Marchall GM; Porcu M; Takita J; Trujillo DC; Van Den Wyngaert I; Van Roy N; Van Goethem A; Van Maerken T; Zabrocki P; Cools J; Schulte JH; Vialard J; Speleman F; De Preter K, 2015, 'Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma: Implications for targeted treatment', Clinical Cancer Research, 21, pp. 3327 - 3339,

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2015, 'Erratum: Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression (Journal of the National Cancer Institute (2014) 106:7 (dju113) DOI: 10.1093/jnci/dju113)', Journal of the National Cancer Institute, 107,

Beckers A; Peer GV; Carter DR; Mets E; Althoff K; Cheung BB; Schulte JH; Mestdagh P; Vandesompele J; Marshall GM; De Preter KD; Speleman F, 2015, 'MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formation', Oncotarget, 6, pp. 5204 - 5216,

Bingul M; Cheung BB; Kumar N; Black DS, 2015, 'ChemInform Abstract: Synthesis of Symmetrical and Unsymmetrical Diindolylmethanes via Acid-Catalyzed Electrophilic Substitution Reactions.', ChemInform, 46, pp. no - no,

Fabian J; Opitz D; Althoff K; Lodrini M; Astrahantseff K; Hero B; Volland R; Beckers A; Preter K; Patil NS; Abba ML; Thole TM; Wünschel J; Künkele A; Hu J; Schweizer L; Mechtersheimer G; Carter DR; Cheung BB; Popanda O; Deimling A; Henrich K-O; Westermann F; Schwab M; Koster J; Versteeg R; Marshall GM; Speleman F; Zoeller M; Allgayer H; Fischer M; Berthold F; Kulozik AE; Witt O; Eggert A; Schulte JH; Deubzer HE, 2015, 'MYCN transcriptionally represses CD9 to trigger an invasion-metastasis cascade in neuroblastoma', Molecular and Cellular Pediatrics, 2, pp. A13 - A13,

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2014, 'Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression', Journal of the National Cancer Institute, 106,

Tee EL; Ling D; Nelson C; Atmadibrata B; Dinger M; XU N; Mizukami T; Liu PY; Liu B; Cheung B; Pasquier E; Haber M; Norris MD; Suzuki T; Marshall GM; Liu T, 2014, 'The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1', Oncotarget, 5, pp. 1793 - 1804,

Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, 96, pp. 1 - 12,

Bingul M; Cheung BB; Kumar N; Black DSC, 2014, 'Synthesis of symmetrical and unsymmetrical diindolylmethanes via acid-catalysed electrophilic substitution reactions', Tetrahedron, 70, pp. 7363 - 7369,

Marshall GM; Carter DR; Cheung BB; Liu T; Mateos MK; Meyerowitz JG; Weiss WA, 2014, 'The prenatal origins of cancer', Nature Reviews Cancer, 14, pp. 277 - 289,

Sutton SK; Koach J; Tan O; Liu B; Carter DR; Wilmott JS; Yosufi B; Haydu LE; Mann GJ; Thompson JF; Long GV; Liu T; McArthur G; Zhang XD; Scolyer RA; Cheung BB; Marshall GM, 2014, 'TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells', Oncotarget, 5, pp. 10127 - 10139,

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