By Associate Professor John Zaunders

Book Chapters

Zaunders J; Estaquier J; Corbeil J, 2005, 'Elevated apoptosis of CD8+ T lymphocytes during HIV-1 infection', in Cell Death During HIV Infection, pp. 229 - 251

Journal articles

Farrell R; Zaunders J; Poynten IM; Anderson L; Evans L, 2024, 'Concurrent nonavalent human papillomavirus (HPV) vaccination and immune stimulation with imiquimod to treat recalcitrant HPV-associated high grade vaginal intra-epithelial neoplasia', Gynecologic Oncology Reports, 52, http://dx.doi.org/10.1016/j.gore.2024.101350

Gao X; Shen Q; Roco JA; Dalton B; Frith K; Mee Ling Munier C; Ballard FD; Wang K; Kelly HG; Nekrasov M; He JS; Jaeger R; Carreira P; Ellyard JI; Beattie L; Enders A; Cook MC; Zaunders JJ; Cockburn IA, 2024, 'Zeb2 drives the formation of CD11c⁺ atypical B cells to sustain germinal centers that control persistent infection', Science Immunology, 9, http://dx.doi.org/10.1126/sciimmunol.adj4748

Dyer WB; Suzuki K; Levert A; Starr M; Lloyd AR; Zaunders JJ, 2024, 'Preservation of functionality, immunophenotype, and recovery of HIV RNA from PBMCs cryopreserved for more than 20 years', Frontiers in Immunology, 15, http://dx.doi.org/10.3389/fimmu.2024.1382711

Pathmanandavel K; Le S; Xie S; Alves M; Foley E; Kelleher A; Zaunders J; Carr A; Tong W; Breit S; Sewell W; Kane A, 2024, 'Novel clinical applications of functional assays to measure antigen-specific cellular immunity', Pathology, 56, pp. S27 - S27, http://dx.doi.org/10.1016/j.pathol.2023.12.101

Cook L; Zaunders J; Seddiki N; van Bockel D; Kelleher AD; Munier CML, 2023, 'Parallel analysis of multiple human memory CD4⁺ T-cell subsets within antigen-specific responses using cell proliferation dyes', Immunology and Cell Biology, 101, pp. 171 - 178, http://dx.doi.org/10.1111/imcb.12606

Khoo WH; Jackson K; Phetsouphanh C; Zaunders JJ; Alquicira-Hernandez J; Yazar S; Ruiz-Diaz S; Singh M; Dhenni R; Kyaw W; Tea F; Merheb V; Lee FXZ; Burrell R; Howard-Jones A; Koirala A; Zhou L; Yuksel A; Catchpoole DR; Lai CL; Vitagliano TL; Rouet R; Christ D; Tang B; West NP; George S; Gerrard J; Croucher PI; Kelleher AD; Goodnow CG; Sprent JD; Powell JE; Brilot F; Nanan R; Hsu PS; Deenick EK; Britton PN; Phan TG, 2023, 'Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19', Clinical Immunology, 246, http://dx.doi.org/10.1016/j.clim.2022.109209

Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks ML; Law H; Danwilai T; Starr M; Munier CML; Christ D; Singh M; Croucher PI; Brilot-Turville F; Turville S; Phan TG; Dore GJ; Darley D; Cunningham P; Matthews GV; Kelleher AD; Zaunders JJ, 2022, 'High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1032911

Suzuki K; Zaunders J; Gates TM; Levert A; Butterly S; Liu Z; Ishida T; Palmer S; Rae CD; Jugé L; Cysique LA; Brew BJ, 2022, 'Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury', Proceedings of the National Academy of Sciences of the United States of America, 119, pp. 1 - 11, http://dx.doi.org/10.1073/pnas.2210584119

Massey J; Jackson K; Singh M; Hughes B; Withers B; Ford C; Khoo M; Hendrawan K; Zaunders J; Charmeteau-De Muylder B; Cheynier R; Luciani F; Ma D; Moore J; Sutton I, 2022, 'Haematopoietic Stem Cell Transplantation Results in Extensive Remodelling of the Clonal T Cell Repertoire in Multiple Sclerosis', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.798300

Visweswaran M; Hendrawan K; Massey JC; Khoo ML; Ford CD; Zaunders JJ; Withers B; Sutton IJ; Ma DDF; Moore JJ, 2022, 'Sustained immunotolerance in multiple sclerosis after stem cell transplant', Annals of Clinical and Translational Neurology, 9, pp. 206 - 220, http://dx.doi.org/10.1002/acn3.51510

Law H; Mach M; Howe A; Obeid S; Milner B; Carey C; Elfis M; Fsadni B; Ognenovska K; Phan TG; Carey D; Xu Y; Venturi V; Zaunders J; Kelleher AD; Munier CML, 2022, 'Early expansion of CD38+ICOS+ GC Tfh in draining lymph nodes during influenza vaccination immune response', iScience, 25, pp. 103656, http://dx.doi.org/10.1016/j.isci.2021.103656

Petitdemange C; Funderburg N; Zaunders J; Corbeau P, 2021, 'Editorial: Infectious Agent-Induced Chronic Immune Activation: Causes, Phenotypes, and Consequences', Frontiers in Immunology, 12, pp. 740556, http://dx.doi.org/10.3389/fimmu.2021.740556

Suzuki K; Levert A; Yeung J; Starr M; Cameron J; Williams R; Rismanto N; Stark T; Druery D; Prasad S; Ferrarini C; Hanafi I; McNally LP; Cunningham P; Liu Z; Ishida T; Huang CS; Oswald V; Evans L; Symonds G; Brew BJ; Zaunders J, 2021, 'HIV-1 viral blips are associated with repeated and increasingly high levels of cell-associated HIV-1 RNA transcriptional activity', AIDS, 35, pp. 2095 - 2103, http://dx.doi.org/10.1097/QAD.0000000000003001

Mak G; Zaunders JJ; Bailey M; Seddiki N; Rogers G; Leong L; Phan TG; Kelleher AD; Koelsch KK; Boyd MA; Danta M, 2021, 'Preservation of Gastrointestinal Mucosal Barrier Function and Microbiome in Patients With Controlled HIV Infection', Frontiers in Immunology, 12, pp. 688886, http://dx.doi.org/10.3389/fimmu.2021.688886

Frith K; Munier CML; Hastings L; Mowat D; Wilson M; Seddiki N; Macintosh R; Kelleher AD; Gray P; Zaunders JJ, 2021, 'The role of zeb2 in human cd8 t lymphocytes: Clinical and cellular immune profiling in mowat–wilson syndrome', International Journal of Molecular Sciences, 22, pp. 5324, http://dx.doi.org/10.3390/ijms22105324

Murray DD; Zaunders J; Milliken ST; Mee Ling Munier C; Ford C; Orla Morrissey C; Visweswaran M; Avery S; Sasadeusz J; Kwan J; Desai S; Law M; Koelsch KK; Lewin SR; Moore J; Kelleher AD; Polizzotto MN; Munier ML; Law M, 2021, 'Altered Immune Reconstitution in Allogeneic Stem Cell Transplant Recipients with Human Immunodeficiency Virus (HIV)', Clinical Infectious Diseases, 72, pp. 1141 - 1146, http://dx.doi.org/10.1093/cid/ciaa748

Zaunders J; Phetsouphanh C, 2021, 'Long-term and short-term immunity to SARS-CoV-2: Why it matters', Microbiology Australia, 42, pp. 34 - 38, http://dx.doi.org/10.1071/MA21010

Seddiki N; Zaunders J; Phetsouphanh C; Brezar V; Xu Y; McGuire HM; Bailey M; McBride K; Hey-Cunningham W; Munier CML; Cook L; Kent S; Lloyd A; Cameron B; De St Groth BF; Koelsch K; Danta M; Hocini H; Levy Y; Kelleher AD, 2021, 'CD73⁺ CD127^high long-term memory CD4 T cells are highly proliferative in response to recall antigens and are early targets in hiv-1 infection', International Journal of Molecular Sciences, 22, pp. 1 - 28, http://dx.doi.org/10.3390/ijms22020912

Sasson SC; Zaunders JJ; Nahar K; Munier CML; Fairfax BP; Olsson-Brown A; Jolly C; Read SA; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Payne MJ; Cheung VTF; Gupta T; Klenerman P; Long GV; Brain O; Menzies AM; Kelleher AD, 2020, 'Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis', Clinical and Experimental Immunology, 202, pp. 335 - 352, http://dx.doi.org/10.1111/cei.13502

Zaunders J; Mee Ling Munier C; McGuire HM; Law H; Howe A; Xu Y; De St Groth BF; Schofield P; Christ D; Milner B; Obeid S; Dyer WB; Saksena NK; Kelleher AD; Munier ML, 2020, 'Mapping the extent of heterogeneity of human CCR5R CD4R T cells in peripheral blood and lymph nodes', AIDS, 34, pp. 833 - 848, http://dx.doi.org/10.1097/QAD.0000000000002503

Cook L; Munier CML; Seddiki N; Hardy MY; Anderson RP; Zaunders J; Tye-Din JA; Kelleher AD; van Bockel D, 2020, 'Circulating gluten-specific, but not CMV-specific, CD39⁺ regulatory T cells have an oligoclonal TCR repertoire', Clinical and Translational Immunology, 9, pp. e1096, http://dx.doi.org/10.1002/cti2.1096

Moore JJ; Massey JC; Ford CD; Khoo ML; Zaunders JJ; Hendrawan K; Barnett Y; Barnett MH; Kyle KA; Zivadinov R; Ma KC; Milliken ST; Sutton IJ; Ma DDF, 2019, 'Prospective phase II clinical trial of autologous haematopoietic stem cell transplant for treatment refractory multiple sclerosis', Journal of Neurology, Neurosurgery and Psychiatry, 90, pp. 514 - 521, http://dx.doi.org/10.1136/jnnp-2018-319446

Zaunders J; Dyer WB; Churchill M; Munier CML; Cunningham PH; Suzuki K; McBride K; Hey-Nguyen W; Koelsch K; Wang B; Hiener B; Palmer S; Gorry PR; Bailey M; Xu Y; Danta M; Seddiki N; Cooper DA; Saksena NK; Sullivan JS; Riminton S; Learmont J; Kelleher AD, 2019, 'Possible clearance of transfusion-acquired nef/LTR-deleted attenuated HIV-1 infection by an elite controller with CCR5 Delta 32 heterozygous and HLA-B57 genotype', JOURNAL OF VIRUS ERADICATION, 5, pp. 73 - 83, http://dx.doi.org/10.1016/s2055-6640(20)30056-x

Zaunders J, 2019, 'Intersection of immune checkpoints and CD8⁺ T cell noncytolytic suppression of HIV-1 infection: Putting on the brakes versus the nuclear option', AIDS, 33, pp. 581 - 583, http://dx.doi.org/10.1097/QAD.0000000000002069

Moso MA; Anderson JL; Adikari S; Gray LR; Khoury G; Chang JJ; Jacobson JC; Ellett AM; Cheng WJ; Saleh S; Zaunders JJ; Purcell DFJ; Cameron PU; Churchill MJ; Lewin SR; Lu HK, 2019, 'HIV latency can be established in proliferating and nonproliferating resting CD4 T cells in vitro: Implications for latency reversal', AIDS, 33, pp. 199 - 209, http://dx.doi.org/10.1097/qad.0000000000002075

Hey-Nguyen WJ; Bailey M; Xu Y; Suzuki K; Van Bockel D; Finlayson R; Leigh Brown A; Carr A; Cooper DA; Kelleher AD; Koelsch KK; Zaunders JJ, 2019, 'HIV-1 DNA Is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure', AIDS Research and Human Retroviruses, 35, pp. 112 - 120, http://dx.doi.org/10.1089/aid.2018.0235

Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, '1303P Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', Annals of Oncology, 30, pp. v530, http://dx.doi.org/10.1093/annonc/mdz253.128

Moran I; Nguyen A; Khoo WH; Butt D; Bourne K; Young C; Hermes JR; Biro M; Gracie G; Ma CS; Munier CML; Luciani F; Zaunders J; Parker A; Kelleher AD; Tangye SG; Croucher PI; Brink R; Read MN; Phan TG, 2018, 'Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes', Nature Communications, 9, pp. 3372, http://dx.doi.org/10.1038/s41467-018-05772-7

Cook L; Munier CML; Seddiki N; van Bockel D; Ontiveros N; Hardy MY; Gillies JK; Levings MK; Reid HH; Petersen J; Rossjohn J; Anderson RP; Zaunders JJ; Tye-Din JA; Kelleher AD, 2017, 'Circulating gluten-specific FOXP3⁺CD39⁺ regulatory T cells have impaired suppressive function in patients with celiac disease', Journal of Allergy and Clinical Immunology, 140, pp. 1592 - 1603.e8, http://dx.doi.org/10.1016/j.jaci.2017.02.015

Murray JM; Zaunders J; Emery S; Cooper DA; Hey-Nguyen WJ; Koelsch KK; Kelleher AD, 2017, 'HIV dynamics linked to memory CD4+ T cell homeostasis', PLoS ONE, 12, pp. e0186101, http://dx.doi.org/10.1371/journal.pone.0186101

Phetsouphanh C; Xu Y; Munier ML; Zaunders JJ; Kelleher AD, 2017, 'Single-cell profiling of lineage determining transcription factors in antigen-specific CD4⁺ T cells reveals unexpected complexity in recall responses during immune reconstitution', Immunology and Cell Biology, 95, pp. 640 - 646, http://dx.doi.org/10.1038/icb.2017.28

Koelsch KK; Rasmussen TA; Hey-Nguyen WJ; Pearson C; Xu Y; Bailey M; Marks KH; Sasson SC; Taylor MS; Tantau R; Obeid S; Milner B; Morrissey O; Pinto AN; Suzuki K; Busch MP; Keating SM; Kaiser P; Yukl S; Wong JK; Hiener BM; Palmer S; Zaunders J; Post JJ; Chan DJ; Avery S; Milliken ST; Kelleher AD; Lewin SR; Cooper DA; Cooper D, 2017, 'Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals', Journal of Acquired Immune Deficiency Syndromes, 75, pp. 328 - 337, http://dx.doi.org/10.1097/QAI.0000000000001381

Hey-Nguyen WJ; Xu Y; Pearson CF; Bailey M; Suzuki K; Tantau R; Obeid S; Milner B; Field A; Carr A; Bloch M; Cooper DA; Kelleher AD; Zaunders JJ; Koelsch KK, 2017, 'Quantification of Residual Germinal Center Activity and HIV-1 DNA and RNA Levels Using Fine Needle Biopsies of Lymph Nodes during Antiretroviral Therapy', AIDS Research and Human Retroviruses, 33, pp. 648 - 657, http://dx.doi.org/10.1089/aid.2016.0171

Zaunders J; Xu Y; Kent SJ; Koelsch KK; Kelleher AD, 2017, 'Divergent expression of CXCR5 and CCR5 on CD4⁺ T cells and the paradoxical accumulation of T follicular helper cells during HIV infection', Frontiers in Immunology, 8, pp. 495, http://dx.doi.org/10.3389/fimmu.2017.00495

Xu Y; Phetsouphanh C; Suzuki K; Aggrawal A; Graff-Dubois S; Roche M; Bailey M; Alcantara S; Cashin K; Sivasubramaniam R; Koelsch KK; Autran B; Harvey R; Gorry PR; Moris A; Cooper DA; Turville S; Kent SJ; Kelleher AD; Zaunders J; Aggarwal A, 2017, 'HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells', Frontiers in Immunology, 8, pp. 376, http://dx.doi.org/10.3389/fimmu.2017.00376

Juno JA; Bockel DV; Kent SJ; Kelleher AD; Zaunders JJ; Munier CML, 2017, 'Cytotoxic CD4 T cells-friend or foe during viral infection?', Frontiers in Immunology, 8, http://dx.doi.org/10.3389/fimmu.2017.00019

Zaunders J; Howe A; Ledger S; Kelleher A; Murray J; Symonds G, 2017, '23 Knockdown of CCR5 expression in antigen-specific cytotoxic CD4 T cells', Journal of Virus Eradication, 3, pp. 14 - 15, http://dx.doi.org/10.1016/s2055-6640(20)30728-7

Keoshkerian E; Hunter M; Cameron B; Nguyen N; Sugden P; Bull R; Zekry A; Maher L; Seddiki N; Zaunders J; Kelleher A; Lloyd AR; Dolan K; Haber P; Rawlinson W; Treloar C; Dore G; Luciani F, 2016, 'Hepatitis C-specific effector and regulatory CD4 T-cell responses are associated with the outcomes of primary infection', Journal of Viral Hepatitis, 23, pp. 985 - 993, http://dx.doi.org/10.1111/jvh.12576

Zaunders J; Danta M; Bailey M; Mak G; Marks K; Seddiki N; Xu Y; Templeton DJ; Cooper DA; Boyd MA; Kelleher AD; Koelsch KK, 2016, 'CD4⁺ T follicular helper and IgA⁺ B cell numbers in gut biopsies from HIV-infected subjects on antiretroviral therapy are similar to HIV-uninfected individuals', Frontiers in Immunology, 7, pp. 438, http://dx.doi.org/10.3389/fimmu.2016.00438

Munier CML; van Bockel D; Bailey M; Ip S; Xu Y; Alcantara S; Liu SM; Denyer G; Kaplan W; Suzuki K; Croft N; Purcell A; Tscharke D; Cooper DA; Kent SJ; Zaunders JJ; Kelleher AD, 2016, 'The primary immune response to Vaccinia virus vaccination includes cells with a distinct cytotoxic effector CD4 T-cell phenotype', Vaccine, 34, pp. 5251 - 5261, http://dx.doi.org/10.1016/j.vaccine.2016.09.009

Cook L; Zaunders JJ; Kelleher AD, 2016, 'Comment on "A cytokine- independent approach to identify antigen-specific human germinal center T follicular helper cells and rare antigen-specific CD41 T cells in blood', Journal of Immunology, 197, pp. 2557 - 2558, http://dx.doi.org/10.4049/jimmunol.1601311

Mak G; Zaunders JJ; Bailey M; Seddiki N; Xu Y; Cooper D; Boyd M; Kelleher A; Danta M; Koelsch KK, 2016, 'Gut integrity, CD4+T follicular helper cells, and IgA plus B cells in gastrointestinal-associated lymphoid tissue following ART', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31, pp. 6 - 6, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384664700008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Li J; Hardy K; Phetsouphanh C; Tu WJ; Sutcliffe EL; McCuaig R; Sutton CR; Zafar A; Mee Ling Munier C; Zaunders JJ; Xu Y; Theodoratos A; Tan A; SiewLim P; Knaute T; Masch A; Zerweck J; Brezar V; Milburn PJ; Dunn J; Casarotto MG; Turner SJ; Seddiki N; Kelleher AD; Rao S; Munier ML, 2016, 'Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4⁺T cells through p65 and H2B phosphorylation', Journal of Cell Science, 129, pp. 2448 - 2461, http://dx.doi.org/10.1242/jcs.181248

Zaunders J; Jing J; Leipold M; Maecker H; Kelleher AD; Koch I, 2016, 'Computationally efficient multidimensional analysis of complex flow cytometry data using second order polynomial histograms', Cytometry Part A, 89, pp. 44 - 58, http://dx.doi.org/10.1002/cyto.a.22704

Phetsouphanh C; Zaunders JJ; Kelleher AD, 2015, 'Detecting antigen-specific T cell responses: From bulk populations to single cells', International Journal of Molecular Sciences, 16, pp. 18878 - 18893, http://dx.doi.org/10.3390/ijms160818878

Hey-Cunningham WJ; Murray JM; Natarajan V; Amin J; Moore CL; Emery S; Cooper DA; Zaunders J; Kelleher AD; Koelsch KK; PINT study team ; Danta M, 2015, 'Early antiretroviral therapy with raltegravir generates sustained reductions in HIV reservoirs but not lower T-cell activation levels.', AIDS, 29, pp. 911 - 919, http://dx.doi.org/10.1097/QAD.0000000000000625

Tong WWY; Shepherd K; Garland S; Meagher A; Templeton DJ; Fairley CK; Jin F; Poynten IM; Zaunders J; Hillman RJ; Grulich AE; Kelleher AD; Carr A; Acraman B; Fraissard E; Law C; McGrath P; Mellor R; Norris R; O'Dwyer M; Seeds D; Thompson K; Varma R; Adams M; Biro C; Cornall A; Crampton L; Ekman D; Ellard J; Farnsworth A; Feeney L; Howard K; Hyne S; Law M; Machalek D; McCaffery K; McDonald R; Pendlebury S; Petoumenos K; Phillips S; Prestage G; Richards A; Roberts J; Schema L; Segelov E; Tabrizi S; Thurloe J; Bailey M; Cunningham P; Fsadni B; Grassi K; Ip S; Lograsso M; McBride K; Merlin K; Munier M-L; Piperias M; Xu Y, 2015, 'Human Papillomavirus 16-Specific T-Cell Responses and Spontaneous Regression of Anal High-Grade Squamous Intraepithelial Lesions', Journal of Infectious Diseases, 211, pp. 405 - 415, http://dx.doi.org/10.1093/infdis/jiu461

Phetsouphanh C; Xu Y; Zaunders J, 2015, 'CD4 T cells mediate both positive and negative regulation of the immune response to HIV infection: Complex role of T follicular helper cells and regulatory T cells in pathogenesis', Frontiers in Immunology, 6, http://dx.doi.org/10.3389/fimmu.2014.00681

Zaunders J; Jing J; Leipold M; Maecker H; Kelleher AD; Koch I, 2015, 'Computationally efficient multidimensional analysis of complex flow cytometry data using second order polynomial histograms', Cytometry Part A, 89, pp. 44 - 58, http://dx.doi.org/10.1002/cyto.a.22704

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