Select Publications
Conference Papers
, 2017, 'Solution structure of the Mitoxantrone-DNA complex: A NMR and molecular modelling study', in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, SPRINGER, SCOTLAND, British Biophys Soc, Edinburgh, pp. S228 - S228, presented at
, 2010, 'Insights into the cellular responses against different DNA-binding agents', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, GERMANY, Berlin, pp. 105 - 105, presented at
, 2008, 'Bisintercalating threading agents as cytotoxic inhibitors of transcription', in EJC Supplements, Pergamon-Elsevier Science Ltd, Kidlington, Oxford, England, pp. 83 - 84, presented at
, 2008, 'Poisoning of human topoisomerase II alpha by acridinecarboxamides and related cytotoxins', in EJC Supplements, Pergamon-Elsevier Science Ltd, Kidlington, Oxford, England, pp. 28 - 28, presented at
, 2006, 'Cycometallated platinum and palladium complexes as anticancer agents: Everything old is new again', in Australia and New Zealand Symposium on Organometallic Chemistry OZOM3, Monash university, Gippsland, Australia, pp. 47 - 47, presented at
, 2005, 'DNA Intercalation by bix(phenazinecarboxamides): Structural Insights Into Anticancer Activity', in Apte S; Kable S; Baker AT (eds.), Connect 2005 - Chemical Challenges for the 21st Century, Sydney, Convention Centre, Darling Harbour, Sydney, pp. M017 PO Bi - -, presented at
, 2005, 'Mutations within the alpha4 helix of human DNA topoisomerase IIalpha confer differential sensitivities to topoisomerase poisons.', in Proceedings of the American Association for Cancer Research vol 46, American Association for Cancer Research, Philadelphia, USA, pp. 2401 - 2401, presented at
, 2003, 'Effects of bisintercalating DNA threading agents on transcription in human leukemic CCRF-CEM cells studied by microarray analysis', in CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MASSACHUSETTS, BOSTON, pp. 6082S - 6082S, presented at
, 2002, 'CRYSTAL STRUCTURES OF ACRIDINE-4-CARBOXAMIDES COMPLEXED WITH THE DNA HEXANUCLEOTIDE d(CGTACG)2', in ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, INT UNION CRYSTALLOGRAPHY, pp. C55 - C55, http://dx.doi.org/10.1107/S0108767302087317
, 2001, 'Characterisation of the DNA complex of an antitumour-active bifunctional polybenzamide alkylating agent using electrospray and MALDI-TOF mass spectrometry.', in Clinical Cancer Research vol 7, AMER ASSOC CANCER RESEARCH, PO BOX 11806, BIRMINGHAM, AL 35202 USA, Birmingham, USA., pp. 3796S - 3796S, presented at
, 2001, 'Crystal structure of 9-amino[N-(2-morpholino)ethyl]acridine-4-carboxamide bound to d(CGTACG)2: A DNA complex of a biologically inactive derivative of the acridinecarboxamide topoisomerase poisons.', in Clinical Cancer Research vol 7, AMER ASSOC CANCER RESEARCH, PO BOX 11806, BIRMINGHAM, AL 35202 USA, Birmingham, USA., pp. 3798S - 3798S, presented at
, 2000, 'Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)-acridine-4-carboxamides.', in Clinical Cancer Research vol 6, AMER ASSOC CANCER RESEARCH, PO BOX 11806, BIRMINGHAM, AL 35202 USA, Birmingham, USA, pp. 4531S - 4531S, presented at
, 1999, 'Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2.', in Clinical Cancer Research vol 5, AMER ASSOC CANCER RESEARCH, PO BOX 11806, BIRMINGHAM, AL 35202 USA, Birmingham, USA., pp. 3854S - 3854S, presented at
, 1990, 'CONFORMATIONAL DISTORTIONS INDUCED IN DNA UPON BINDING OF CISPLATIN AND INTERCALATING ANALOGS', in European Journal of Pharmacology Vol 183, Elsevier, Amsterdam, Netherlands, pp. 191 - 192, http://dx.doi.org/10.1016/0014-2999(90)93025-L
, 1984, 'Cytotoxicity of DNA intercalating platinum (II) complexes.', in Medical and Pediatric Oncology vol 13, WILEY-LISS, DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012, New York, USA, pp. 137 - 138, presented at
, 1984, 'Kinetics of the interaction between 9-aminoacridinecarboxamides and DNA.', in Medical and Pediatric Oncology vol 13, WILEY-LISS, DIV JOHN WILEY & SONS INC 605 THIRD AVE, NEW YORK, NY 10158-0012, New York, USA, pp. 134 - 135, presented at
, 1984, 'Cytotoxicity of DNA intercalating platinum (II) complexes.', in Proceedings of the Australian Biochemical Society 1984, PROC AUST BIOCHEMICAL SOC, MONASH UNIV DEPT BIOCHEMISTRY, CLAYTON VICTORIA 3168, AUSTRALIA, Clayton, Victoria, Australia, pp. S44 - S44, presented at
, 1984, 'Interaction of diacridines and diquinolines with adrenoceptors.', in Proceedings of the Australian Biochemical Society vol 16, PROC AUST BIOCHEMICAL SOC, MONASH UNIV DEPT BIOCHEMISTRY, CLAYTON VICTORIA 3168, AUSTRALIA, Clayton, Victoria, Australia, pp. S87 - S87, presented at
, 1984, 'Interaction of diacridines with intracellular DNA.', in Proceedings of the Australian Biochemical Society Vol 16, PROC AUST BIOCHEMICAL SOC, MONASH UNIV DEPT BIOCHEMISTRY, CLAYTON VICTORIA 3168, AUSTR, Clayton, Victoria, Australia, pp. S19 - S19, presented at
, 1983, 'The interaction of diacridines with cellular DNA.', in Medical and Pediatric Oncology vol 12, WILEY-LISS, DIV JOHN WILEY & SONS INC, 605 THIRD AVE, NEW YORK, NY 10158-0012, New York, USA, pp. 278 - 278, presented at