Researcher

Associate Professor Luke Hunter

My Expertise

Organic chemistry, Fluorine chemistry, Natural products and Peptides

Biography

I completed my PhD at The University of Sydney in 2005. I then undertook a series of postdoctoral positions at The University of Melbourne, The University of St Andrews (UK) and UNSW. In 2009, my independent career commenced with the award of a University of Sydney Postdoctoral Research Fellowship. In 2011, I was appointed as a Lecturer in Chemistry at UNSW, and since then I have been promoted to Senior Lecturer (2014) and Associate Professor...view more

I completed my PhD at The University of Sydney in 2005. I then undertook a series of postdoctoral positions at The University of Melbourne, The University of St Andrews (UK) and UNSW. In 2009, my independent career commenced with the award of a University of Sydney Postdoctoral Research Fellowship. In 2011, I was appointed as a Lecturer in Chemistry at UNSW, and since then I have been promoted to Senior Lecturer (2014) and Associate Professor (2019). My research interests are broadly in the areas of organic synthesis and medicinal chemistry, with a frequent focus on fluorinated target molecules.


My Grants

RESEARCH GRANTS:

  • Cooperative Research Centres Projects (CRC-P) (2020–2022): $3,000,000
  • ARC Discovery Project (2018–2020): $416,584
  • ARC Discovery Project (2014–2016): $345,000
  • ARC Discovery Early Career Research Award (2012–2014): $375,000
  • UNSW Major Research Equipment Grant (2013): $90,000
  • UNSW Faculty Research Grant Program (2018): $20,000
  • UNSW Faculty Research Grant Program (2016): $20,000
  • UNSW Faculty of Science Interdisciplinary Research Grant (2013): $3,000
  • University of Sydney Postdoctoral Research Fellowship (2009–2011): $300,00

TEACHING GRANTS:

  • ARC Industrial Transformation Training Centre (2018–2023): $3,279,502
  • UNSW Learning & Teaching Strategic Development and Enhancement Funding (2018–2019): $200,000
  • UNSW Learning & Teaching Strategic Development and Enhancement Funding (2014–2015): $200,000
  • UNSW Learning & Teaching Innovation Grant (2015): $20,000
  • UNSW Learning & Teaching Innovation Grant (2014): $25,000

My Qualifications

  • Bachelor of Advanced Science (Honours Class 1 and University Medal), The University of Sydney, 1997-2000
  • Ph.D. in Chemistry, The University of Sydney, 2001-2004.
  • Graduate Certificate in University Learning and Teaching, UNSW, 2012-2013

My Awards

  • 2018 Vice-Chancellor's Award for Teaching Excellence
  • 2016 Vice-Chancellor's Award for Teaching Excellence
  • 2017 Fellow of the UNSW Scientia Education Academy (5-year term)
  • 2015 Tasmanian Alkaloids Lectureship
  • 2012 ARC Discovery Early Career Researcher Award (DECRA)
  • 2009 University of Sydney Postdoctoral Research Fellowship
  • 2000 University Medal

My Research Activities

Research in the Hunter group focuses on natural products chemistry, peptidomimetics, bioactive molecules and synthetic methodology. A strong theme of organofluorine chemistry underpins several of these research areas. 

Fluorine is a small element that packs a big punch. When fluorine atoms are incorporated into organic molecules, they can have a dramatic impact on the substances' physical and chemical properties, and this leads to a wealth of applications in pharmaceuticals, agrochemicals, liquid crystals and polymers. In the Hunter group we are particularly interested in developing new methods to synthesise organofluorine compounds, and in using fluorine atoms to control molecular conformation (a kind of "molecular origami"). The highly polarised C-F bond tends to align in very particular ways with adjacent functional groups, due to a variety of subtle stereoelectronic effects. In our lab, we harness these effects to produce novel bioactive molecules that are constrained into optimal 3D shapes, controlled by the precise positioning of fluorine atoms. The research is interdisciplinary in nature, and we collaborate extensively to analyse the biological properties of the molecules that we create.

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Location

Dalton building (F12), room 221

Contact

54474
56141