Journal articles
McGahan W; Gough M; Liu C; Hoyte S; Gill AJ; Cavallucci D; Cooper C; Butler N; Yeung S; Kryza T; Gulhane B; Latter MJ; Waddell N; Samra JS; Simpson F; Pajic M; Thomas PA; O'Rourke T; Hooper JD, 2024, 'Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT', Gastroenterology, 167, pp. 1217 - 1220, http://dx.doi.org/10.1053/j.gastro.2024.06.033
Tyma V; Liew Y-F; Tran A; Howell A; Ritchie S; Pancreatic Cancer Matrix Atlas AA; Genome Initiative AP; Cox T; Pajic M; Herrmann D; Pereira B; Timpson P; Gordon K, 2024, 'Abstract A067: Identifying and targeting FOLFIRINOX resistance mechanisms to improve outcomes in pancreatic cancer', Cancer Research, 84, pp. A067 - A067, http://dx.doi.org/10.1158/1538-7445.pancreatic24-a067
Colino-Sanguino Y; Rodriguez de la Fuente L; Gloss B; Law AMK; Handler K; Pajic M; Salomon R; Gallego-Ortega D; Valdes-Mora F, 2024, 'Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues', Heliyon, 10, http://dx.doi.org/10.1016/j.heliyon.2024.e37185
Pereira BA; Ritchie S; Chambers CR; Gordon KA; Magenau A; Murphy KJ; Nobis M; Tyma VM; Liew YF; Lucas MC; Naeini MM; Barkauskas DS; Chacon-Fajardo D; Howell AE; Parker AL; Warren SC; Reed DA; Lee V; Metcalf XL; Lee YK; O'Regan LP; Zhu J; Trpceski M; Fontaine ARM; Stoehr J; Rouet R; Lin X; Chitty JL; Porazinski S; Wu SZ; Filipe EC; Cadell AL; Holliday H; Yang J; Papanicolaou M; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Vennin C; Yin J; Dew AB; McMillan PJ; Goldstein LD; Deveson IW; Croucher DR; Samuel MS; Sim HW; Batten M; Chantrill L; Grimmond SM; Gill AJ; Samra J; Jeffry Evans TR; Sasaki T; Phan TG; Swarbrick A; Sansom OJ; Morton JP; Pajic M; Parker BL; Herrmann D; Cox TR; Timpson P, 2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197
Upton D; Fajardo DC; Omari S; Porazinski S; McLean B; Schuhmacher D; Istadi A; Kothari V; Finkelstein D; Machajewski T; Rock F; Turner S; Pajic M, 2024, 'Abstract 6575: Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response', Cancer Research, 84, pp. 6575 - 6575, http://dx.doi.org/10.1158/1538-7445.am2024-6575
Pajic M; McLean B; Fajardo DC; Porazinski S; Upton DH; Schuhmacher D; Istadi A; Cox T; Timpson P; Wilcock DJ; Anderson KJ; Mason H; Guisot NE; Jones CD; Phillips C; Armer R, 2024, 'Abstract 720: Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer', Cancer Research, 84, pp. 720 - 720, http://dx.doi.org/10.1158/1538-7445.am2024-720
Istadi A; Porazinski S; Pajic M, 2024, 'Cancer variant modeling in vivo', Nature Biotechnology, 42, pp. 383 - 385, http://dx.doi.org/10.1038/s41587-023-02080-4
Pitiyarachchi O; Lin FP; Spooner A; Sharbeen G; Barker HP; Thornton K; Collignon E; Ballinger ML; Thomas DM; Magenau A; Porazinski S; Raina A; Sjoquist KM; Chantrill LA; Gebski V; Sowmya A; Timpson P; Pajic M; Goldstein D; Phillips PA, 2024, '1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', Annals of Oncology, 35, pp. S925 - S925, http://dx.doi.org/10.1016/j.annonc.2024.08.1576
Chitty JL; Yam M; Perryman L; Parker AL; Skhinas JN; Setargew YFI; Mok ETY; Tran E; Grant RD; Latham SL; Pereira BA; Ritchie SC; Murphy KJ; Trpceski M; Findlay AD; Melenec P; Filipe EC; Nadalini A; Velayuthar S; Major G; Wyllie K; Papanicolaou M; Ratnaseelan S; Phillips PA; Sharbeen G; Youkhana J; Russo A; Blackwell A; Hastings JF; Lucas MC; Chambers CR; Reed DA; Stoehr J; Vennin C; Pidsley R; Zaratzian A; Da Silva AM; Tayao M; Charlton B; Herrmann D; Nobis M; Clark SJ; Biankin AV; Johns AL; Croucher DR; Nagrial A; Gill AJ; Grimmond SM; Chantrill LA; Chou A; Dwarte T; Metcalf XL; Jeong G; Kenyon L; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeo D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J, 2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y
Rodriguez-Martin B; Alvarez EG; Baez-Ortega A; Zamora J; Supek F; Demeulemeester J; Santamarina M; Temes J; Garcia-Souto D; Detering H; Li Y; Rodriguez-Castro J; Dueso-Barroso A; Bruzos AL; Dentro SC; Blanco MG; Contino G; Ardeljan D; Tojo M; Roberts ND; Zumalave S; Edwards PA; Weischenfeldt J; Puiggròs M; Chong Z; Chen K; Lee EA; Wala JA; Raine KM; Butler A; Waszak SM; Navarro FCP; Schumacher SE; Monlong J; Maura F; Bolli N; Gerstein M; Park PJ; Wedge DC; Beroukhim R; Torrents D; Korbel JO; Martincorena I; Fitzgerald RC; Van Loo P; Kazazian HH; Burns KH; Akdemir KC; Boutros PC; Bowtell DDL; Brors B; Campbell PJ; Chan K; Chen K; Cortés-Ciriano I; Dunford AJ; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gordenin DA; Haan D; Haber JE; Hess JM; Hutter B; Imielinski M; Jones DTW; Ju YS; Kazanov MD; Klimczak LJ; Koh Y; Kumar K; Lee JJK; Lynch AG; Macintyre G; Markowetz F; Martinez-Fundichely A; Meyerson M; Miyano S; Nakagawa H; Navarro FCP; Ossowski S; Pearson JV; Rippe K; Roberts SA, 2023, 'Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (Nature Genetics, (2020), 52, 3, (306-319), 10.1038/s41588-019-0562-0)', Nature Genetics, 55, pp. 1080, http://dx.doi.org/10.1038/s41588-023-01319-9
Yakneen S; Waszak SM; Aminou B; Bartolome J; Boroevich KA; Boyce R; Brooks AN; Buchanan A; Buchhalter I; Butler AP; Byrne NJ; Cafferkey A; Campbell PJ; Chen Z; Cho S; Choi W; Clapham P; Davis-Dusenbery BN; De La Vega FM; Demeulemeester J; Dow MT; Dursi LJ; Eils J; Eils R; Ellrott K; Farcas C; Favero F; Fayzullaev N; Ferretti V; Flicek P; Fonseca NA; Gelpi JL; Getz G; Gibson B; Grossman RL; Harismendy O; Heath AP; Heinold MC; Hess JM; Hofmann O; Hong JH; Hudson TJ; Hutter B; Hutter CM; Hübschmann D; Imoto S; Ivkovic S; Jeon SH; Jiao W; Jung J; Kabbe R; Kahles A; Kerssemakers JNA; Kim HL; Kim H; Kim J; Kim Y; Kleinheinz K; Koscher M; Koures A; Kovacevic M; Lawerenz C; Leshchiner I; Liu J; Livitz D; Mihaiescu GL; Mijalkovic S; Mijalkovic Lazic A; Miyano S; Miyoshi N; Nahal-Bose HK; Nakagawa H; Nastic M; Newhouse SJ; Nicholson J; O’Connor BD; Ocana D; Ohi K; Ohno-Machado L; Omberg L; Ouellette BFF; Paramasivam N; Perry MD; Pihl TD; Prinz M; Puiggròs M; Radovic P; Raine KM; Rheinbay E; Rosenberg M; Royo R; Rätsch G; Saksena G; Schlesner M; Shorser SI; Short C; Sofia HJ; Spring J; Stein LD; Struck AJ, 2023, 'Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes (Nature Biotechnology, (2020), 38, 3, (288-292), 10.1038/s41587-019-0360-3)', Nature Biotechnology, 41, pp. 577, http://dx.doi.org/10.1038/s41587-022-01554-1
Rheinbay E; Nielsen MM; Abascal F; Wala JA; Shapira O; Tiao G; Hornshøj H; Hess JM; Juul RI; Lin Z; Feuerbach L; Sabarinathan R; Madsen T; Kim J; Mularoni L; Shuai S; Lanzós A; Herrmann C; Maruvka YE; Shen C; Amin SB; Bandopadhayay P; Bertl J; Boroevich KA; Busanovich J; Carlevaro-Fita J; Chakravarty D; Chan CWY; Craft D; Dhingra P; Diamanti K; Fonseca NA; Gonzalez-Perez A; Guo Q; Hamilton MP; Haradhvala NJ; Hong C; Isaev K; Johnson TA; Juul M; Kahles A; Kahraman A; Kim Y; Komorowski J; Kumar K; Kumar S; Lee D; Lehmann KV; Li Y; Liu EM; Lochovsky L; Park K; Pich O; Roberts ND; Saksena G; Schumacher SE; Sidiropoulos N; Sieverling L; Sinnott-Armstrong N; Stewart C; Tamborero D; Umer HM; Uusküla-Reimand L; Wadelius C; Wadi L; Yao X; Zhang CZ; Zhang J; Haber JE; Hobolth A; Imielinski M; Kellis M; Lawrence MS; von Mering C; Nakagawa H; Raphael BJ; Rubin MA; Sander C; Stein LD; Stuart JM; Tsunoda T; Wheeler DA; Johnson R; Reimand J; Gerstein M; Khurana E; Campbell PJ; López-Bigas N; Bader GD; Barenboim J; Beroukhim R; Brunak S; Campbell PJ, 2023, 'Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (Nature, (2020), 578, 7793, (102-111), 10.1038/s41586-020-1965-x)', Nature, 614, pp. E40, http://dx.doi.org/10.1038/s41586-022-05599-9
Calabrese C; Davidson NR; Demircioğlu D; Fonseca NA; He Y; Kahles A; Lehmann KV; Liu F; Shiraishi Y; Soulette CM; Urban L; Greger L; Li S; Liu D; Perry MD; Xiang Q; Zhang F; Zhang J; Bailey P; Erkek S; Hoadley KA; Hou Y; Huska MR; Kilpinen H; Korbel JO; Marin MG; Markowski J; Nandi T; Pan-Hammarström Q; Pedamallu CS; Siebert R; Stark SG; Su H; Tan P; Waszak SM; Yung C; Zhu S; Awadalla P; Creighton CJ; Meyerson M; Ouellette BFF; Wu K; Yang H; Amin SB; Bailey P; Chateigner A; Cortés-Ciriano I; Craft B; Frenkel-Morgenstern M; Goldman M; Khurana E; Lamaze FC; Li C; Li X; Li X; Liu X; Nielsen MM; Ojesina AI; Park PJ; Pedersen JS, 2023, 'Author Correction: Genomic basis for RNA alterations in cancer (Nature, (2020), 578, 7793, (129-136), 10.1038/s41586-020-1970-0)', Nature, 614, pp. E37, http://dx.doi.org/10.1038/s41586-022-05596-y
Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MRR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A; Bailey MH; Bailey PJ; Balasundaram M; Balu S; Bandopadhayay P; Banks RE; Barbi S; Barbour AP; Barenboim J; Barnholtz-Sloan J; Barr H; Barrera E; Bartlett J; Bartolome J; Bassi C; Bathe OF; Baumhoer D; Bavi P; Baylin SB; Bazant W; Beardsmore D; Beck TA; Behjati S; Behren A; Niu B; Bell C; Beltran S; Benz C; Berchuck A; Bergmann AK; Bergstrom EN; Berman BP; Berney DM; Bernhart SH; Beroukhim R; Berrios M; Bersani S; Bertl J; Betancourt M; Bhandari V; Bhosle SG; Biankin AV; Bieg M; Bigner D; Binder H; Birney E; Birrer M; Biswas NK; Bjerkehagen B; Bodenheimer T; Boice L; Bonizzato G; De Bono JS, 2023, 'Author Correction: Pan-cancer analysis of whole genomes (Nature, (2020), 578, 7793, (82-93), 10.1038/s41586-020-1969-6)', Nature, 614, pp. E39, http://dx.doi.org/10.1038/s41586-022-05598-w
Li Y; Roberts ND; Wala JA; Shapira O; Schumacher SE; Kumar K; Khurana E; Waszak S; Korbel JO; Haber JE; Imielinski M; Akdemir KC; Alvarez EG; Baez-Ortega A; Beroukhim R; Boutros PC; Bowtell DDL; Brors B; Burns KH; Campbell PJ; Chan K; Chen K; Cortés-Ciriano I; Dueso-Barroso A; Dunford AJ; Edwards PA; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gerstein M; Gordenin DA; Haan D; Hess JM; Hutter B; Jones DTW; Ju YS; Kazanov MD; Klimczak LJ; Koh Y; Lee EA; Lee JJK; Lynch AG; Macintyre G; Markowetz F; Martincorena I; Martinez-Fundichely A; Meyerson M; Miyano S; Nakagawa H; Navarro FCP; Ossowski S; Park PJ; Pearson JV; Puiggròs M; Rippe K; Roberts SA; Rodriguez-Martin B; Scully R; Shackleton M; Sidiropoulos N; Sieverling L; Stewart C; Torrents D; Tubio JMC; Villasante I; Waddell N; Weischenfeldt J; Yang L; Yao X; Yoon SS; Zamora J; Zhang CZ; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M, 2023, 'Author Correction: Patterns of somatic structural variation in human cancer genomes (Nature, (2020), 578, 7793, (112-121), 10.1038/s41586-019-1913-9)', Nature, 614, pp. E38, http://dx.doi.org/10.1038/s41586-022-05597-x
Gerstung M; Jolly C; Leshchiner I; Dentro SC; Gonzalez S; Rosebrock D; Mitchell TJ; Rubanova Y; Anur P; Yu K; Tarabichi M; Deshwar A; Wintersinger J; Kleinheinz K; Vázquez-García I; Haase K; Jerman L; Sengupta S; Macintyre G; Malikic S; Donmez N; Livitz DG; Cmero M; Demeulemeester J; Schumacher S; Fan Y; Yao X; Lee J; Schlesner M; Boutros PC; Bowtell DDL; Zhu H; Getz G; Imielinski M; Beroukhim R; Sahinalp SC; Ji Y; Peifer M; Markowetz F; Mustonen V; Yuan K; Wang W; Morris QD; Adams DJ; Campbell PJ; Cao S; Christie EL; Cun Y; Dawson KJ; Drews RM; Fittall M; Garsed DW; Ha G; Lee-Six H; Martincorena I; Oesper L; Peto M; Raphael BJ; Salcedo A; Shi R; Shin SJ; Spiro O; Stein LD; Vembu S, 2023, 'Author Correction: The evolutionary history of 2,658 cancers (Nature, (2020), 578, 7793, (122-128), 10.1038/s41586-019-1907-7)', Nature, 614, pp. E42, http://dx.doi.org/10.1038/s41586-022-05601-4
Alexandrov LB; Kim J; Haradhvala NJ; Huang MN; Tian Ng AW; Wu Y; Boot A; Covington KR; Gordenin DA; Bergstrom EN; Islam SMA; Lopez-Bigas N; Klimczak LJ; McPherson JR; Morganella S; Sabarinathan R; Wheeler DA; Mustonen V; Boutros P; Chan K; Fujimoto A; Getz G; Kazanov M; Lawrence M; Martincorena I; Nakagawa H; Polak P; Prokopec S; Roberts SA; Rozen SG; Saini N; Shibata T; Shiraishi Y; Stratton MR; Teh BT; Vázquez-García I; Yousif F; Yu W; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MRR, 2023, 'Author Correction: The repertoire of mutational signatures in human cancer (Nature, (2020), 578, 7793, (94-101), 10.1038/s41586-020-1943-3)', Nature, 614, pp. E41, http://dx.doi.org/10.1038/s41586-022-05600-5
Poh AR; O'Brien M; Chisanga D; He H; Baloyan D; Traichel J; Dijkstra C; Chopin M; Nutt S; Whitehead L; Boon L; Parkin A; Lowell C; Pajic M; Shi W; Nikfarjam M; Ernst M, 2022, 'Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis', Cell Reports, 41, http://dx.doi.org/10.1016/j.celrep.2022.111479
Khan T; Lyons NJ; Gough M; Kwah KKX; Cuda TJ; Snell CE; Tse BW; Sokolowski KA; Pearce LA; Adams TE; Rose SE; Puttick S; Pajic M; Adams MN; He Y; Hooper JD; Kryza T, 2022, 'CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy', Theranostics, 12, pp. 6915 - 6930, http://dx.doi.org/10.7150/thno.78171
Dreyer SB; Upstill-Goddard R; Legrini A; Biankin AV; Allison S; Beraldi D; Cameron E; Chang DK; Cooke SL; Cunningham R; Grimwood P; Kelly S; Marshall J; McDade B; Musgrove EA; Ramsay D; Evers L; Rebus S; Rahib L; Serrels B; Jamieson NB; McKay CJ; Westwood P; Williams N; Duthie F; Shen W; Pea A; Johns AL; Gill AJ; Chantrill LA; Timpson P; Chou A; Pajic M; Dwarte T; Herrmann D; Vennin C; Cox TR; Pereira B; Ritchiee S; Reed DA; Chambers CR; Metcalf X; Nobis M; Jeong G; Kenyon L; Lyons RJ; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O'Rourke TJ; Fawcett JW, 2022, 'Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence', Gastroenterology, 162, pp. 320 - 324.e4, http://dx.doi.org/10.1053/j.gastro.2021.09.022
McLean B; Istadi A; Clack T; Vankan M; Schramek D; Neely GG; Pajic M, 2022, 'A CRISPR Path to Finding Vulnerabilities and Solving Drug Resistance: Targeting the Diverse Cancer Landscape and Its Ecosystem.', Adv Genet (Hoboken), 3, pp. 2200014, http://dx.doi.org/10.1002/ggn2.202200014
Lakis V; Lawlor RT; Newell F; Patch AM; Mafficini A; Sadanandam A; Koufariotis LT; Johnston RL; Leonard C; Wood S; Rusev B; Corbo V; Luchini C; Cingarlini S; Landoni L; Salvia R; Milella M; Chang D; Bailey P; Jamieson NB; Duthie F; Gingras MC; Muzny DM; Wheeler DA; Gibbs RA; Milione M; Chantrill LA; Timpson P; Chou A; Pajic M; Murphy A; Dwarte T; Hermann D; Vennin C; Cox TR; Pereira B; Ritchie S; Reed DA; Chambers CR; Metcalf X; Nobis M; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Xu Q; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Ballal M; Fletcher DR; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Dixon J; Scardoni M; Bassi C; Grimaldi S; Cantù C; Bonizzato G; Bersani S; Biankin A; Johns A; Herrmann D, 2021, 'DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association', Communications Biology, 4, pp. 155, http://dx.doi.org/10.1038/s42003-020-01469-0
Liu D; Sharbeen G; Phillips P; Johns AL; Gill AJ; Chantrill LA; Timpson P; Chou A; Pajic M; Dwarte T; Herrmann D; Vennin C; Cox TR; Pereira B; Ritchie S; Reed DA; Chambers CR; Metcalf X; Nobis M; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Scarpa A; Lawlor RT; Corbo V; Bassi C; Biankin AV; Jamieson NB; Chang DK; Dreyer SB; Ford CE, 2021, 'ROR1 and ROR2 expression in pancreatic cancer', BMC Cancer, 21, http://dx.doi.org/10.1186/s12885-021-08952-9
Satgunaseelan L; Porazinski S; Strbenac D; Istadi A; Willet C; Chew T; Sadsad R; Palme CE; Lee JH; Boyer M; Yang JYH; Clark JR; Pajic M; Gupta R, 2021, 'Oral Squamous Cell Carcinoma in Young Patients Show Higher Rates of EGFR Amplification: Implications for Novel Personalized Therapy', Frontiers in Oncology, 11, http://dx.doi.org/10.3389/fonc.2021.750852
Lundy J; Gearing LJ; Gao H; West AC; McLeod L; Deswaerte V; Yu L; Porazinski S; Pajic M; Hertzog PJ; Croagh D; Jenkins BJ, 2021, 'TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma', Oncogene, 40, pp. 6007 - 6022, http://dx.doi.org/10.1038/s41388-021-01992-2
Murphy KJ; Reed DA; Vennin C; Conway JRW; Nobis M; Yin JX; Chambers CR; Pereira BA; Lee V; Filipe EC; Trpceski M; Ritchie S; Lucas MC; Warren SC; Skhinas JN; Magenau A; Metcalf XL; Stoehr J; Major G; Parkin A; Bidanel R; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Abdulkhalek L; Gill AJ; Johns AL; Biankin AV; Samra J; Grimmond SM; Chou A; Goetz JG; Samuel MS; Lyons JG; Burgess A; Caldon CE; Horvath LG; Daly RJ; Gadegaard N; Wang Y; Sansom OJ; Morton JP; Cox TR; Pajic M; Herrmann D; Timpson P, 2021, 'Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abh0363
Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
Kryza T; Khan T; Lovell S; Harrington BS; Yin J; Porazinski S; Pajic M; Koistinen H; Rantala JK; Dreyer T; Magdolen V; Reuning U; He Y; Tate EW; Hooper JD, 2021, 'Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1', Nature Chemical Biology, 17, pp. 776 - 783, http://dx.doi.org/10.1038/s41589-021-00783-w
Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z, 2021, 'Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma', FASEB Journal, 35, http://dx.doi.org/10.1096/fj.202002279R
Dreyer SB; Upstill-Goddard R; Paulus-Hock V; Paris C; Lampraki EM; Dray E; Serrels B; Caligiuri G; Rebus S; Plenker D; Galluzzo Z; Brunton H; Cunningham R; Tesson M; Nourse C; Bailey UM; Jones MD; Moran-Jones K; Wright DW; Duthie F; Oien K; Evers L; McKay CJ; McGregor GA; Gulati A; Brough R; Bajrami I; Pettitt S; Dziubinski ML; Candido J; Balkwill F; Barry ST; Grützmann R; Rahib L; Allison S; Bailey PJ; Biankin AV; Beraldi D; Cameron E; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; Martin S; McDade B; McElroy D; Musgrove EA; Ramsay D; Wright D; Hair J; Jamieson NB; Westwood P; Williams N; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Biankin A; Toon CCW; Pavey D; Merrett N; asghari R; Chang D; Pereira B, 2021, 'Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer', Gastroenterology, 160, pp. 362 - 377.e13, http://dx.doi.org/10.1053/j.gastro.2020.09.043
Li CH; Prokopec SD; Sun RX; Yousif F; Schmitz N; Al-Shahrour F; Atwal G; Bailey PJ; Biankin AV; Boutros PC; Campbell PJ; Chang DK; Cooke SL; Deshpande V; Faltas BM; Faquin WC; Garraway L; Getz G; Grimmond SM; Haider S; Hoadley KA; Jiao W; Kaiser VB; Karlić R; Kato M; Kübler K; Lazar AJ; Louis DN; Margolin A; Martin S; Nahal-Bose HK; Nielsen GP; Nik-Zainal S; Omberg L; P’ng C; Perry MD; Polak P; Rheinbay E; Rubin MA; Semple CA; Sgroi DC; Shibata T; Siebert R; Smith J; Stein LD; Stobbe MD; Thai K; Wright DW; Wu CL; Yuan K; Zhang J; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Aukema S; Auman JT; Aure MR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A; Pajic M; Merrett N; Pinese M; Lau L; Gill A; Toon CCW; Chou A; Johns A, 2020, 'Sex differences in oncogenic mutational processes', Nature Communications, 11, pp. 4330, http://dx.doi.org/10.1038/s41467-020-17359-2
Man J; Pajic M; Joshua AM, 2020, 'Fats and mets, KRAS-driven lipid dysregulation affects metastatic potential in pancreatic cancer', Cancer Research, 80, pp. 4886 - 4887, http://dx.doi.org/10.1158/0008-5472.CAN-20-3082
Dreyer SB; Pinese M; Jamieson NB; Scarlett CJ; Colvin EK; Pajic M; Johns AL; Humphris JL; Wu J; Cowley MJ; Chou A; Nagrial AM; Chantrill L; Chin VT; Jones MD; Moran-Jones K; Carter CR; Dickson EJ; Samra JS; Merrett ND; Gill AJ; Kench JG; Duthie F; Miller DK; Cooke S; Aust D; Knösel T; Rümmele P; Grützmann R; Pilarsky C; Nguyen NQ; Musgrove EA; Bailey PJ; McKay CJ; Biankin AV; Chang DK, 2020, 'Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer', Annals of Surgery, 272, pp. 366 - 376, http://dx.doi.org/10.1097/SLA.0000000000003143
Brunton H; Caligiuri G; Cunningham R; Upstill-Goddard R; Bailey UM; Garner IM; Nourse C; Dreyer S; Jones M; Moran-Jones K; Wright DW; Paulus-Hock V; Nixon C; Thomson G; Jamieson NB; McGregor GA; Evers L; McKay CJ; Gulati A; Brough R; Bajrami I; Pettitt SJ; Dziubinski ML; Barry ST; Grützmann R; Brown R; Curry E; Allison S; Biankin AV; Chang DK; Cooke SL; Grimwood P; Kelly S; Marshall J; McDade B; McElroy D; Ramsay D; Rebus S; Hair J; Westwood P; Williams N; Duthie F; Johns AL; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Martyn-Smith M; Thomas MT; Chantrill LA; Chin VT; Chou A; Cowley MJ; Humphris JL; Mead RS; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Grimmond SM; Waddell N; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Harliwong I; Idrisoglu S; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Newell F; Pearson JV; Quinn M, 2020, 'HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer', Cell Reports, 31, http://dx.doi.org/10.1016/j.celrep.2020.107625
Kokkinos J; Ignacio RMC; Sharbeen G; Boyer C; Gonzales-Aloy E; Goldstein D; McCarroll JA; Phillips PA, 2020, 'Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs', Biomaterials, 240, http://dx.doi.org/10.1016/j.biomaterials.2019.119742
Cipponi A; Goode DL; Bedo J; McCabe MJ; Pajic M; Croucher DR; Rajal AG; Junankar SR; Saunders DN; Lobachevsky P; Papenfuss AT; Nessem D; Nobis M; Warren SC; Timpson P; Cowley M; Vargas AC; Qiu MR; Generali DG; Keerthikumar S; Nguyen U; Corcoran NM; Long GV; Blay J-Y; Thomas DM; McCabe M, 2020, 'MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer', Science
Thejer BM; Adhikary PP; Kaur A; Teakel SL; Van Oosterum A; Seth I; Pajic M; Hannan KM; Pavy M; Poh P; Jazayeri JA; Zaw T; Pascovici D; Ludescher M; Pawlak M; Cassano JC; Turnbull L; Jazayeri M; James AC; Coorey CP; Roberts TL; Kinder SJ; Hannan RD; Patrick E; Molloy MP; New EJ; Fehm TN; Neubauer H; Goldys EM; Weston LA; Cahill MA, 2020, 'PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth', BMC Molecular and Cell Biology, 21, pp. 24, http://dx.doi.org/10.1186/s12860-020-00256-3
Chou A; Brown IS; Kumarasinghe MP; Perren A; Riley D; Kim Y; Pajic M; Steinmann A; Rathi V; Jamieson NB; Verheij J; van Roessel S; Nahm CB; Mittal A; Samra J; Gill AJ, 2020, 'RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas', Modern Pathology, 33, pp. 657 - 664, http://dx.doi.org/10.1038/s41379-019-0373-y
Castillo L; Young AIJ; Mawson A; Schafranek P; Steinmann AM; Nessem D; Parkin A; Johns A; Chou A; Law AMK; Lucas MC; Murphy KJ; Deng N; Gallego-Ortega D; Caldon CE; Timpson P; Pajic M; Ormandy CJ; Oakes SR, 2020, 'MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma', Oncogene, 39, pp. 1821 - 1829, http://dx.doi.org/10.1038/s41388-019-1091-0
Lau MT; Ghazanfar S; Parkin A; Chou A; Rouaen JR; Littleboy JB; Nessem D; Khuong TM; Nevoltris D; Schofield P; Langley D; Christ D; Yang J; Pajic M; Neely GG, 2020, 'Systematic functional identification of cancer multi-drug resistance genes', Genome Biology, 21, http://dx.doi.org/10.1186/s13059-020-1940-8
Campbell PJ; Getz G; Korbel JO; Stuart JM; Jennings JL; Stein LD; Perry MD; Nahal-Bose HK; Ouellette BFF; Li CH; Rheinbay E; Nielsen GP; Sgroi DC; Wu CL; Faquin WC; Deshpande V; Boutros PC; Lazar AJ; Hoadley KA; Louis DN; Dursi LJ; Yung CK; Bailey MH; Saksena G; Raine KM; Buchhalter I; Kleinheinz K; Schlesner M; Zhang J; Wang W; Wheeler DA; Ding L; Simpson JT; O’Connor BD; Yakneen S; Ellrott K; Miyoshi N; Butler AP; Royo R; Shorser SI; Vazquez M; Rausch T; Tiao G; Waszak SM; Rodriguez-Martin B; Shringarpure S; Wu DY; Demidov GM; Delaneau O; Hayashi S; Imoto S; Habermann N; Segre AV; Garrison E; Cafferkey A; Alvarez EG; Heredia-Genestar JM; Muyas F; Drechsel O; Bruzos AL; Temes J; Zamora J; Baez-Ortega A; Kim HL; Mashl RJ; Ye K; DiBiase A; Huang KL; Letunic I; McLellan MD; Newhouse SJ; Shmaya T; Kumar S; Wedge DC; Wright MH; Yellapantula VD; Gerstein M; Khurana E; Marques-Bonet T; Navarro A; Bustamante CD; Siebert R; Nakagawa H; Easton DF; Ossowski S; Tubio JMC; De La Vega FM; Estivill X; Yuen D; Mihaiescu GL; Omberg L; Ferretti V; Sabarinathan R; Pich O; Gonzalez-Perez A; Taylor-Weiner A; Fittall MW; Demeulemeester J; Tarabichi M; Roberts ND; Merrett N; Biankin A; Bowtell D; Chantrill L; Pajic M; Pinese M; Lau L; Kakavand H; Gill A; Chou A; Toon CCW; Johns A, 2020, 'Pan-cancer analysis of whole genomes', Nature, 578, pp. 82 - 93, http://dx.doi.org/10.1038/s41586-020-1969-6
Vennin C; Rath N; Pajic M; Olson MF; Timpson P, 2020, 'Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy', Small GTPases, 11, pp. 45 - 52, http://dx.doi.org/10.1080/21541248.2017.1345712
Kryza T; Khan T; Puttick S; Li C; Sokolowski KA; Tse BWC; Cuda T; Lyons N; Gough M; Yin J; Parkin A; Deryugina EI; Quigley JP; Law RHP; Whisstock JC; Riddell AD; Barbour AP; Wyld DK; Thomas PA; Rose S; Snell CE; Pajic M; He Y; Hooper JD, 2020, 'Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma', Theranostics, 10, pp. 4116 - 4133, http://dx.doi.org/10.7150/thno.43589
Porazinski S; Parkin A; Pajic M, 2020, 'Rho-ROCK Signaling in Normal Physiology and as a Key Player in Shaping the Tumor Microenvironment', , 1223, pp. 99 - 127, http://dx.doi.org/10.1007/978-3-030-35582-1_6
Vennin C; Mélénec P; Rouet R; Nobis M; Cazet AS; Murphy KJ; Herrmann D; Reed DA; Lucas MC; Warren SC; Elgundi Z; Pinese M; Kalna G; Roden D; Samuel M; Zaratzian A; Grey ST; Da Silva A; Leung W; Johns AL; Chantrill LA; Chou A; Steinmann A; Arshi M; Dwarte T; Froio D; Pereira B; Ritchie S; Chambers CR; Metcalf X; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Christ A; Bruxner T; Samra JS; Pavlakis N; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Cooper CL; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Zeps N; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C; Christ D; Cox T; Timpson P; Phillips P; Whitelock J; Pajic M; Gill A; Croucher D, 2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6
Parkin A; Man J; Timpson P; Pajic M, 2019, 'Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy', FEBS Journal, 286, pp. 3510 - 3539, http://dx.doi.org/10.1111/febs.15011
Wang K; Huynh N; Wang X; Pajic M; Parkin A; Man J; Baldwin GS; Nikfarjam M; He H, 2019, 'PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines', American Journal of Translational Research, 11, pp. 3353 - 3364, https://www.ncbi.nlm.nih.gov/pubmed/31312349
Chou A; Pajic M; Gill A, 2019, 'Gene-rearrangement is frequent in pancreatic acinar cell carcinoma', Pathology, 51, pp. S7 - S7, http://dx.doi.org/10.1016/j.pathol.2018.12.010
Blatter S; Pajic M; Guyader C; Gonggrijp M; Kersbergen A; Küçükosmanoğlu A; Sol W; Drost R; Jonkers J; Borst P; Rottenberg S, 2019, 'Targeting drug tolerance of residual BRCA1-mutated mouse mammary tumours', Journal of Comparative Pathology, 166, pp. 101 - 101, http://dx.doi.org/10.1016/j.jcpa.2018.10.008
Chou A; Itchins M; de Reuver PR; Arena J; Clarkson A; Sheen A; Sioson L; Cheung V; Perren A; Nahm C; Mittal A; Samra JS; Pajic M; Gill AJ, 2018, 'ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumors', Human Pathology, 82, pp. 249 - 257, http://dx.doi.org/10.1016/j.humpath.2018.07.032
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